| Graft-versus-host disease |
1.71 |
2.19e-1 |
32/42 (76.19%) |
HLA-DQA1;IL1A;HLA-DOB;...
|
| Inflammatory bowel disease |
1.58 |
3.52e-1 |
58/65 (89.23%) |
HLA-DQA1;IL1A;GATA3;...
|
| Asthma |
1.55 |
3.06e-1 |
25/31 (80.65%) |
HLA-DQA1;FCER1A;PRG2;...
|
| Systemic lupus erythematosus |
1.49 |
4.14e-1 |
45/135 (33.33%) |
HLA-DQA1;ELANE;HLA-DOB;...
|
| Ribosome |
1.45 |
4.46e-1 |
113/158 (71.52%) |
RPS25;RPS5;MRPL15;...
|
| Ovarian steroidogenesis |
1.44 |
4.06e-1 |
41/51 (80.39%) |
AKR1C3;CYP1B1;CYP2J2;...
|
| Allograft rejection |
1.43 |
3.84e-1 |
32/38 (84.21%) |
HLA-DQA1;HLA-DOB;HLA-B;...
|
| Ubiquinone and other terpenoid-quinone biosynthesis |
1.43 |
3.38e-1 |
9/11 (81.82%) |
GGCX;TAT;COQ6;...
|
| Steroid hormone biosynthesis |
1.42 |
3.18e-1 |
43/61 (70.49%) |
AKR1C3;CYP1B1;HSD17B8;...
|
| Antigen processing and presentation |
1.41 |
3.15e-1 |
60/78 (76.92%) |
HLA-DQA1;HSPA2;CD74;...
|
| Protein digestion and absorption |
1.40 |
3.17e-1 |
78/103 (75.73%) |
COL3A1;DPP4;ELN;...
|
| Staphylococcus aureus infection |
1.37 |
3.65e-1 |
72/95 (75.79%) |
HLA-DQA1;CAMP;CFI;...
|
| Type I diabetes mellitus |
1.34 |
4.09e-1 |
38/43 (88.37%) |
HLA-DQA1;IL1A;HLA-DOB;...
|
| Arachidonic acid metabolism |
1.31 |
4.62e-1 |
48/61 (78.69%) |
AKR1C3;CYP2J2;GPX7;...
|
| Neomycin, kanamycin and gentamicin biosynthesis |
1.29 |
5.07e-1 |
5/5 (100%) |
HK2
|
| Coronavirus disease |
1.29 |
4.86e-1 |
215/232 (92.67%) |
IL6R;CYBB;RPS25;...
|
| p53 signaling pathway |
1.28 |
4.78e-1 |
63/73 (86.3%) |
SERPINB5;CCNE2;EI24;...
|
| Intestinal immune network for IgA production |
1.28 |
4.56e-1 |
38/48 (79.17%) |
HLA-DQA1;CXCR4;HLA-DOB;...
|
| Focal adhesion |
1.28 |
4.40e-1 |
180/201 (89.55%) |
TNC;LAMB3;SHC1;...
|
| Glycolysis / Gluconeogenesis |
1.27 |
4.25e-1 |
56/67 (83.58%) |
PKM;FBP1;HK2;...
|
| Pentose phosphate pathway |
1.25 |
4.91e-1 |
25/30 (83.33%) |
RPIA;FBP1;ALDOC
|
| Viral myocarditis |
1.22 |
5.60e-1 |
53/60 (88.33%) |
HLA-DQA1;HLA-DOB;CXADR;...
|
| RNA degradation |
1.21 |
5.75e-1 |
53/79 (67.09%) |
EXOSC4;BTG2;ENO1;...
|
| Fructose and mannose metabolism |
1.19 |
6.05e-1 |
30/33 (90.91%) |
FBP1;HK2;AKR1B10;...
|
| Tryptophan metabolism |
1.17 |
6.52e-1 |
35/42 (83.33%) |
CYP1B1;ACAT2;KYNU;...
|
| Starch and sucrose metabolism |
1.17 |
6.47e-1 |
25/36 (69.44%) |
HK2;MGAM;GBE1;...
|
| Relaxin signaling pathway |
1.17 |
6.35e-1 |
114/129 (88.37%) |
SHC1;COL3A1;EDN1;...
|
| Phagosome |
1.15 |
6.53e-1 |
118/152 (77.63%) |
HLA-DQA1;TUBA1A;COLEC12;...
|
| Carbohydrate digestion and absorption |
1.14 |
6.53e-1 |
37/47 (78.72%) |
SLC2A5;SLC37A4;HK2;...
|
| AGE-RAGE signaling pathway in diabetic complications |
1.13 |
6.54e-1 |
97/100 (97%) |
COL3A1;CDC42;CYBB;...
|
| Gastric cancer |
-1.28 |
4.16e-1 |
122/149 (81.88%) |
CTNNA3;CDH1;LRP5;...
|
| Thyroid cancer |
-1.28 |
4.17e-1 |
36/37 (97.3%) |
RET;MAPK1;DDB2;...
|
| PD-L1 expression and PD-1 checkpoint pathway in cancer |
-1.32 |
4.18e-1 |
79/89 (88.76%) |
CD3D;RAF1;MAPK13;...
|
| Pentose and glucuronate interconversions |
-1.33 |
4.09e-1 |
17/34 (50%) |
UGDH;UGT2B15;UGT2B17;...
|
| Thyroid hormone signaling pathway |
-1.33 |
4.18e-1 |
112/121 (92.56%) |
KRAS;ESR1;TSC2;...
|
| Hepatocellular carcinoma |
-1.35 |
4.24e-1 |
135/168 (80.36%) |
LRP5;RAF1;SMAD3;...
|
| Diabetic cardiomyopathy |
-1.36 |
4.23e-1 |
162/203 (79.8%) |
CD36;RYR2;PLCB3;...
|
| TNF signaling pathway |
-1.41 |
4.12e-1 |
103/112 (91.96%) |
MAPK13;IRF1;FAS;...
|
| mTOR signaling pathway |
-1.42 |
3.84e-1 |
114/154 (74.03%) |
LRP5;RAF1;SKP2;...
|
| Non-small cell lung cancer |
-1.43 |
3.92e-1 |
70/72 (97.22%) |
CDK6;STK4;RET;...
|
| Oxidative phosphorylation |
-1.48 |
2.60e-1 |
93/133 (69.92%) |
LHPP;NDUFS7;ATP6V1E1;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
-1.48 |
2.72e-1 |
62/70 (88.57%) |
MAPK13;ATP6V1E1;NFKBIA;...
|
| Neutrophil extracellular trap formation |
-1.52 |
1.88e-1 |
101/189 (53.44%) |
GP1BA;PLCB3;RAF1;...
|
| Maturity onset diabetes of the young |
-1.53 |
1.88e-1 |
21/26 (80.77%) |
NKX6-1;IAPP;SLC2A2;...
|
| Acute myeloid leukemia |
-1.53 |
1.95e-1 |
66/67 (98.51%) |
NFKB1;CSF1R;MAPK1;...
|
| GnRH secretion |
-1.53 |
1.95e-1 |
60/64 (93.75%) |
CACNA1D;GPER1;TRPC4;...
|
| Ascorbate and aldarate metabolism |
-1.54 |
2.05e-1 |
15/30 (50%) |
AKR1A1;ALDH2;UGDH;...
|
| Signaling pathways regulating pluripotency of stem cell... |
-1.55 |
1.98e-1 |
110/143 (76.92%) |
KRAS;ID2;FZD2;...
|
| Inositol phosphate metabolism |
-1.59 |
1.70e-1 |
66/73 (90.41%) |
MINPP1;PLCB3;MTMR2;...
|
| Collecting duct acid secretion |
-1.60 |
1.70e-1 |
22/27 (81.48%) |
ATP6V1A;ATP6V1B2;ATP6V0E2;...
|
| Valine, leucine and isoleucine degradation |
-1.61 |
1.67e-1 |
42/48 (87.5%) |
HMGCS2;ACADM;PCCA;...
|
| Phosphatidylinositol signaling system |
-1.64 |
1.37e-1 |
82/97 (84.54%) |
CALML5;CALML4;PLCB3;...
|
| Citrate cycle (TCA cycle) |
-1.66 |
1.25e-1 |
30/30 (100%) |
ACO2;IDH2;OGDHL;...
|
| beta-Alanine metabolism |
-1.67 |
1.33e-1 |
25/30 (83.33%) |
ECHS1;GAD2;ALDH6A1;...
|
| Pancreatic secretion |
-1.69 |
1.34e-1 |
87/102 (85.29%) |
RAB8A;CTRL;RYR2;...
|
| Alanine, aspartate and glutamate metabolism |
-1.71 |
1.44e-1 |
27/37 (72.97%) |
GOT1;NIT2;AGXT;...
|
| Pyrimidine metabolism |
-1.73 |
1.55e-1 |
40/56 (71.43%) |
CTPS2;ENTPD3;CTPS1;...
|
| Cysteine and methionine metabolism |
-1.74 |
1.93e-1 |
43/50 (86%) |
MTR;SMS;MPST;...
|
| Chronic myeloid leukemia |
-1.74 |
2.90e-1 |
72/76 (94.74%) |
RB1;MECOM;STAT5B;...
|
| Vibrio cholerae infection |
-1.89 |
5.65e-2 |
44/50 (88%) |
ACTB;ATP6V0B;ARF1;...
|
