Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMNU65W)

• Drug Name: Khellin Drug Info
• Synonyms: khellin; 82-02-0; Visammin; Methafrone; Amicardine; Coronin; Medekellin; Ammivisnagen; Corafurone; Amikellin; Viscardan; Benecardin; Gynokhellan; Ammipuran; Kelourin; Rykellin; Interkhellin; Interkellin; Visammimix; Khellinorm; Khellanals; Khellamine; Kalangin; Deltoside; Ammispasmin; Visnagalin; Khelangin; Kelincor; Kelicorin; Norkel; Kelamin; Simeskellina; Khelloyd; Khelfren; Visnagen; Vasokellina; Kellosal; Mefurina; Lynamine; Khelisem; Kelicor; Chellin; Amiptan; Kellin; Ammivin; Keloid; Kellina; Eskel; Cardio-khellin; Ammi-khellin; Bi-Kellina
• Cross-matching ID:
  PubChem CID: 3828
  ChEBI ID: CHEMBL44746
  CAS Number: CAS 82-02-0
  TTD Drug ID: D0G4KG

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Staphylococcus aureus infection	1.94	7.89e-3	72/95 (75.79%)	KRT17;KRT14;KRT15;...
African trypanosomiasis	-1.88	2.38e-2	32/37 (86.49%)	HPR;PRKCA;IFNG;...
Adrenergic signaling in cardiomyocytes	-1.90	2.38e-2	130/150 (86.67%)	PPP1CB;MYL3;TPM4;...
Cardiac muscle contraction	-2.17	0.00e+0	64/87 (73.56%)	ATP1B4;COX8A;COX4I1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	24H	Hide ▲