| Aminoacyl-tRNA biosynthesis |
1.82 |
1.03e-1 |
15/66 (22.73%) |
QRSL1;IARS2;WARS2;...
|
| Cysteine and methionine metabolism |
1.74 |
1.11e-1 |
43/50 (86%) |
ENOPH1;SMS;LDHB;...
|
| Hypertrophic cardiomyopathy |
1.70 |
1.27e-1 |
81/90 (90%) |
SGCB;CACNA2D2;DES;...
|
| Cardiac muscle contraction |
1.61 |
2.56e-1 |
64/87 (73.56%) |
CACNA2D2;ACTC1;TNNC1;...
|
| beta-Alanine metabolism |
1.52 |
4.52e-1 |
25/30 (83.33%) |
ALDH3A1;HIBCH;GAD1;...
|
| Tyrosine metabolism |
1.50 |
4.40e-1 |
30/36 (83.33%) |
ALDH3A1;TPO;FAH;...
|
| Dilated cardiomyopathy |
1.49 |
4.05e-1 |
86/96 (89.58%) |
SGCB;CACNA2D2;PLN;...
|
| Selenocompound metabolism |
1.47 |
4.20e-1 |
11/17 (64.71%) |
PAPSS1;KYAT3;CTH
|
| Valine, leucine and isoleucine degradation |
1.45 |
4.09e-1 |
42/48 (87.5%) |
ACAA2;DLD;ACAT1;...
|
| alpha-Linolenic acid metabolism |
1.44 |
4.21e-1 |
17/25 (68%) |
PLA2G4C;ACAA1;PLAAT3;...
|
| Legionellosis |
1.44 |
3.87e-1 |
51/57 (89.47%) |
CXCL1;HSPA8;TLR4;...
|
| Glycosaminoglycan degradation |
1.43 |
3.63e-1 |
19/19 (100%) |
HYAL2;GLB1;HYAL1;...
|
| Fatty acid elongation |
1.41 |
3.74e-1 |
19/27 (70.37%) |
ELOVL5;ACAA2;HSD17B12;...
|
| Biosynthesis of unsaturated fatty acids |
1.40 |
3.68e-1 |
21/27 (77.78%) |
ELOVL5;HSD17B12;ACAA1;...
|
| Prion disease |
1.40 |
3.58e-1 |
209/273 (76.56%) |
HSPA8;EGR1;C7;...
|
| Nicotinate and nicotinamide metabolism |
1.35 |
5.04e-1 |
25/35 (71.43%) |
NNMT;NNT;SIRT5;...
|
| Pyruvate metabolism |
1.34 |
4.81e-1 |
41/47 (87.23%) |
DLD;ACAT1;PCK2;...
|
| Tryptophan metabolism |
1.33 |
4.86e-1 |
35/42 (83.33%) |
IDO1;DLD;ACAT1;...
|
| Glycolysis / Gluconeogenesis |
1.33 |
4.76e-1 |
56/67 (83.58%) |
ENO3;DLD;GPI;...
|
| B cell receptor signaling pathway |
1.33 |
4.63e-1 |
71/81 (87.65%) |
CD81;MALT1;RASGRP3;...
|
| Glyoxylate and dicarboxylate metabolism |
1.33 |
4.41e-1 |
23/30 (76.67%) |
DLD;ACAT1;GLUL;...
|
| Primary bile acid biosynthesis |
1.32 |
4.29e-1 |
15/17 (88.24%) |
CYP39A1;CH25H;AMACR;...
|
| Arrhythmogenic right ventricular cardiomyopathy |
1.31 |
4.46e-1 |
70/77 (90.91%) |
SGCB;CACNA2D2;DES;...
|
| Rheumatoid arthritis |
1.30 |
4.59e-1 |
78/93 (83.87%) |
CXCL1;CXCL6;TLR4;...
|
| Folate biosynthesis |
1.29 |
4.75e-1 |
23/26 (88.46%) |
AKR1B1;FPGS;PAH;...
|
| Butanoate metabolism |
1.27 |
5.00e-1 |
23/28 (82.14%) |
ACAT1;BDH1;GAD1;...
|
| Malaria |
1.27 |
4.91e-1 |
44/50 (88%) |
CD81;TLR4;KLRK1;...
|
| Purine metabolism |
1.26 |
5.11e-1 |
102/129 (79.07%) |
ENPP4;GMPR2;NME3;...
|
| Glycosaminoglycan biosynthesis |
1.25 |
5.28e-1 |
40/58 (68.97%) |
HS2ST1;HS3ST2;EXTL2;...
|
| Ether lipid metabolism |
1.23 |
5.30e-1 |
32/49 (65.31%) |
PLA2G4C;PLPP3;PLPP1;...
|
| Lysine degradation |
-1.31 |
4.45e-1 |
51/63 (80.95%) |
COLGALT1;EZH2;SETDB1;...
|
| Regulation of lipolysis in adipocytes |
-1.32 |
4.48e-1 |
52/55 (94.55%) |
AKT3;NPR1;PDE3B;...
|
| Autophagy |
-1.34 |
4.49e-1 |
113/169 (66.86%) |
ATG7;RPS6KB2;STX17;...
|
| Vitamin digestion and absorption |
-1.34 |
4.49e-1 |
17/24 (70.83%) |
APOA4;SLC5A6;APOB;...
|
| Long-term depression |
-1.35 |
4.38e-1 |
55/60 (91.67%) |
GRIA3;GNAQ;GNA12;...
|
| Adherens junction |
-1.35 |
4.51e-1 |
63/71 (88.73%) |
FGFR1;CTNNA1;ACTB;...
|
| Neomycin, kanamycin and gentamicin biosynthesis |
-1.37 |
4.06e-1 |
5/5 (100%) |
HK1;HK3;HK2
|
| Thyroid cancer |
-1.40 |
3.40e-1 |
36/37 (97.3%) |
TP53;RXRA;NCOA4;...
|
| Tight junction |
-1.40 |
3.56e-1 |
130/169 (76.92%) |
RUNX1;ARPC5;MYH14;...
|
| Nitrogen metabolism |
-1.41 |
3.62e-1 |
16/17 (94.12%) |
CA5B;CA4;GLUD1;...
|
| Mitophagy |
-1.42 |
3.53e-1 |
56/68 (82.35%) |
ATG9A;E2F1;CSNK2A1;...
|
| Adipocytokine signaling pathway |
-1.42 |
3.60e-1 |
64/69 (92.75%) |
CD36;AKT3;ACSL5;...
|
| AMPK signaling pathway |
-1.44 |
3.41e-1 |
106/120 (88.33%) |
PPP2R2A;RPS6KB2;HNF4A;...
|
| mTOR signaling pathway |
-1.45 |
3.40e-1 |
114/154 (74.03%) |
AKT3;ULK1;EIF4EBP1;...
|
| Fatty acid biosynthesis |
-1.45 |
3.55e-1 |
16/18 (88.89%) |
CBR4;ACSL5;OXSM;...
|
| Collecting duct acid secretion |
-1.46 |
3.44e-1 |
22/27 (81.48%) |
ATP6V1A;ATP6V0E1;ATP6V0E2;...
|
| Phosphatidylinositol signaling system |
-1.49 |
2.80e-1 |
82/97 (84.54%) |
PIK3CD;PIK3CB;ITPKB;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
-1.49 |
2.91e-1 |
49/53 (92.45%) |
AP2M1;DNM3;DNM1;...
|
| Asthma |
-1.51 |
2.77e-1 |
25/31 (80.65%) |
HLA-DPB1;HLA-DPA1;EPX;...
|
| Ovarian steroidogenesis |
-1.52 |
2.75e-1 |
41/51 (80.39%) |
HSD17B2;BMP6;PLA2G4A;...
|
| PPAR signaling pathway |
-1.52 |
2.98e-1 |
66/74 (89.19%) |
PLTP;CD36;ACSL5;...
|
| Type II diabetes mellitus |
-1.53 |
3.21e-1 |
42/46 (91.3%) |
PIK3CD;PIK3CB;PRKCD;...
|
| Aldosterone-regulated sodium reabsorption |
-1.57 |
2.42e-1 |
34/37 (91.89%) |
SFN;PDPK1;PIK3CA;...
|
| Herpes simplex virus 1 infection |
-1.60 |
2.16e-1 |
165/498 (33.13%) |
HLA-DPB1;NECTIN2;SRSF5;...
|
| Vibrio cholerae infection |
-1.63 |
2.04e-1 |
44/50 (88%) |
ATP6V1A;KDELR3;SEC61B;...
|
| Carbohydrate digestion and absorption |
-1.65 |
2.11e-1 |
37/47 (78.72%) |
PIK3CD;PIK3CB;LCT;...
|
| Steroid biosynthesis |
-1.65 |
2.60e-1 |
19/20 (95%) |
LBR;LSS;CYP27B1;...
|
| Chemical carcinogenesis |
-1.66 |
3.11e-1 |
186/281 (66.19%) |
RPS6KB1;PIK3CD;PIK3CB;...
|
| Porphyrin and chlorophyll metabolism |
-1.72 |
2.18e-1 |
23/43 (53.49%) |
GUSB;UGT2B4;BLVRA;...
|
| Ferroptosis |
-1.82 |
1.45e-1 |
36/41 (87.8%) |
LPCAT3;ACSL5;SLC7A11;...
|
