Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMOQK8Z)

Drug Name
Arbidol Drug Info
Synonyms Umifenovir; Arbidole; MC-101
Cross-matching ID
PubChem CID
131411
ChEBI ID
CHEMBL134730
CAS Number
CAS 131707-25-0
TTD Drug ID
D02VIT

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Steroid biosynthesis 2.12 0.00e+0 19/20 (95%) DHCR24;DHCR7;FDFT1;...
Protein digestion and absorption 1.97 1.50e-2 78/103 (75.73%) COL16A1;COL5A2;COL10A1;...
Apelin signaling pathway -1.74 4.05e-2 117/137 (85.4%) ADCY2;GABARAPL1;PPARGC1A;...
Oxytocin signaling pathway -1.75 4.09e-2 128/154 (83.12%) CAMK2A;CACNB4;ADCY2;...
Hematopoietic cell lineage -1.76 4.31e-2 90/99 (90.91%) CD2;CSF2RA;IL1R2;...
Alcoholism -1.77 4.61e-2 86/186 (46.24%) SLC6A3;CREB3;PRKACA;...
Fc gamma R-mediated phagocytosis -1.79 2.77e-2 79/97 (81.44%) RAF1;PIP5K1B;CFL1;...
Long-term depression -1.82 2.52e-2 55/60 (91.67%) HRAS;MAPK3;MAPK1;...
Adherens junction -1.83 2.94e-2 63/71 (88.73%) PTPRJ;TGFBR1;MAPK3;...
Renin secretion -1.90 6.29e-3 61/69 (88.41%) NPR1;PLCB4;GUCY1A1;...
Bacterial invasion of epithelial cells -2.29 0.00e+0 59/77 (76.62%) DNM2;ARHGAP10;GAB1;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 0.04uM - 10uM 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 0.04uM - 10uM 24H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 0.04uM - 10uM 24H
Peripheral blood
T-cell acute lymphoblastic leukemia
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Jurkat CVCL_0367 Homo sapiens 0.04uM - 10uM 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 0.04uM - 10uM 24H