| Nitrogen metabolism |
1.62 |
6.74e-1 |
16/17 (94.12%) |
CA12;CA2;GLUD1;...
|
| Proximal tubule bicarbonate reclamation |
1.58 |
4.68e-1 |
21/23 (91.3%) |
CA2;AQP1;FXYD2;...
|
| AGE-RAGE signaling pathway in diabetic complications |
1.55 |
3.92e-1 |
97/100 (97%) |
VCAM1;MAPK13;THBD;...
|
| Glycolysis / Gluconeogenesis |
1.49 |
5.07e-1 |
56/67 (83.58%) |
PGAM1;ENO2;FBP1;...
|
| Ubiquinone and other terpenoid-quinone biosynthesis |
1.48 |
4.42e-1 |
9/11 (81.82%) |
HPD;COQ3;COQ7;...
|
| Phenylalanine metabolism |
1.41 |
6.94e-1 |
14/17 (82.35%) |
GOT2;GLYAT;HPD;...
|
| Renal cell carcinoma |
1.40 |
6.51e-1 |
68/69 (98.55%) |
PAK6;CRK;TGFA;...
|
| Arginine and proline metabolism |
1.39 |
5.87e-1 |
39/50 (78%) |
GOT2;PRODH;CKB;...
|
| Central carbon metabolism in cancer |
1.39 |
5.38e-1 |
67/70 (95.71%) |
PGAM1;SIRT3;PFKP;...
|
| Tyrosine metabolism |
1.37 |
5.44e-1 |
30/36 (83.33%) |
ADH7;GOT2;DCT;...
|
| D-Glutamine and D-glutamate metabolism |
1.36 |
5.32e-1 |
5/5 (100%) |
GLUD1;GLUD2;GLS2;...
|
| Fructose and mannose metabolism |
1.30 |
7.13e-1 |
30/33 (90.91%) |
FBP1;PFKP;TPI1;...
|
| TGF-beta signaling pathway |
1.29 |
7.01e-1 |
81/94 (86.17%) |
BMP2;ID3;E2F5;...
|
| mRNA surveillance pathway |
1.02 |
9.86e-1 |
71/98 (72.45%) |
GSPT1;RNPS1;MAGOHB;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
0.90 |
9.90e-1 |
49/53 (92.45%) |
FXYD2;KL;ADCY9;...
|
| Tight junction |
0.87 |
9.88e-1 |
130/169 (76.92%) |
CLDN10;MYH10;SYNPO;...
|
| B cell receptor signaling pathway |
0.85 |
9.86e-1 |
71/81 (87.65%) |
NFATC3;IFITM1;NFKBIB;...
|
| Mismatch repair |
0.85 |
9.86e-1 |
22/23 (95.65%) |
RFC5;EXO1;POLD2;...
|
| Platelet activation |
0.85 |
9.77e-1 |
106/124 (85.48%) |
MAPK13;GUCY1B1;NOS3;...
|
| Endocytosis |
0.83 |
9.82e-1 |
198/252 (78.57%) |
FOLR1;EHD2;RAB11FIP5;...
|
| Carbohydrate digestion and absorption |
0.83 |
9.80e-1 |
37/47 (78.72%) |
FXYD2;HK2;LCT;...
|
| GnRH signaling pathway |
0.83 |
9.72e-1 |
80/93 (86.02%) |
MAPK13;EGR1;CALML3;...
|
| Cytokine-cytokine receptor interaction |
0.82 |
9.69e-1 |
246/295 (83.39%) |
CXCL14;BMP2;CXCL6;...
|
| Calcium signaling pathway |
0.82 |
9.61e-1 |
213/240 (88.75%) |
NTRK2;EDNRB;CALML3;...
|
| Protein export |
0.81 |
9.77e-1 |
17/23 (73.91%) |
SPCS3;SRP14;SRP72;...
|
| Cellular senescence |
0.79 |
9.89e-1 |
139/156 (89.1%) |
MAPK13;CHEK1;NFATC3;...
|
| Intestinal immune network for IgA production |
0.78 |
9.91e-1 |
38/48 (79.17%) |
CD40;CXCL12;TGFB1;...
|
| Thermogenesis |
0.78 |
9.91e-1 |
173/232 (74.57%) |
NDUFA4L2;MAPK13;CREB1;...
|
| Insulin resistance |
0.77 |
9.87e-1 |
96/108 (88.89%) |
PPP1R3C;NOS3;CREB1;...
|
| Fanconi anemia pathway |
0.75 |
9.90e-1 |
36/54 (66.67%) |
BRIP1;HES1;CENPX;...
|
| Metabolism of xenobiotics by cytochrome P450 |
-1.36 |
3.45e-1 |
49/77 (63.64%) |
GSTT1;GSTM3;UGT2B4;...
|
| Viral myocarditis |
-1.38 |
3.38e-1 |
53/60 (88.33%) |
DAG1;ABL1;FYN;...
|
| Influenza A |
-1.38 |
3.44e-1 |
156/172 (90.7%) |
IRF7;TLR7;MAVS;...
|
| Peroxisome |
-1.38 |
3.45e-1 |
72/82 (87.8%) |
BAAT;CROT;ABCD4;...
|
| Thiamine metabolism |
-1.39 |
3.45e-1 |
12/15 (80%) |
ALPG;ACP1;AK4;...
|
| Herpes simplex virus 1 infection |
-1.40 |
3.37e-1 |
165/498 (33.13%) |
PPP1CB;IFNA6;IRF9;...
|
| Necroptosis |
-1.41 |
3.21e-1 |
113/159 (71.07%) |
JAK1;CHMP7;VDAC1;...
|
| Ovarian steroidogenesis |
-1.41 |
3.30e-1 |
41/51 (80.39%) |
ADCY8;HSD17B1;HSD3B2;...
|
| Folate biosynthesis |
-1.42 |
3.22e-1 |
23/26 (88.46%) |
SPR;GCH1;ALPG;...
|
| Ascorbate and aldarate metabolism |
-1.43 |
3.14e-1 |
15/30 (50%) |
GUSB;ALDH2;UGT2B4;...
|
| Glycosaminoglycan degradation |
-1.43 |
3.19e-1 |
19/19 (100%) |
IDS;HYAL4;HEXA;...
|
| Biosynthesis of unsaturated fatty acids |
-1.43 |
3.24e-1 |
21/27 (77.78%) |
HACD2;ELOVL4;BAAT;...
|
| Hematopoietic cell lineage |
-1.44 |
3.25e-1 |
90/99 (90.91%) |
HLA-DQB1;KIT;CSF2RA;...
|
| Sulfur relay system |
-1.45 |
3.18e-1 |
5/8 (62.5%) |
MPST;TST
|
| Regulation of lipolysis in adipocytes |
-1.46 |
2.94e-1 |
52/55 (94.55%) |
ADORA1;PTGER3;GNAI1;...
|
| Ribosome |
-1.47 |
3.05e-1 |
113/158 (71.52%) |
RPL10L;RPS4X;RPL31;...
|
| Legionellosis |
-1.48 |
2.92e-1 |
51/57 (89.47%) |
HSPA1L;RELA;TLR5;...
|
| Melanoma |
-1.48 |
3.11e-1 |
68/72 (94.44%) |
ARAF;PDGFB;AKT1;...
|
| Neutrophil extracellular trap formation |
-1.49 |
3.07e-1 |
101/189 (53.44%) |
PLCG1;CLCN4;RAC1;...
|
| Chemical carcinogenesis |
-1.50 |
3.21e-1 |
186/281 (66.19%) |
HSP90AA1;CYP2C18;AKT1;...
|
| SNARE interactions in vesicular transport |
-1.54 |
2.38e-1 |
19/33 (57.58%) |
SNAP23;STX16;STX11;...
|
| Acute myeloid leukemia |
-1.54 |
2.57e-1 |
66/67 (98.51%) |
ARAF;AKT1;MAPK1;...
|
| Porphyrin and chlorophyll metabolism |
-1.55 |
2.67e-1 |
23/43 (53.49%) |
ALAD;CP;GUSB;...
|
| Ferroptosis |
-1.55 |
2.87e-1 |
36/41 (87.8%) |
PCBP1;GCLM;ACSL6;...
|
| Fat digestion and absorption |
-1.56 |
2.85e-1 |
35/43 (81.4%) |
ACAT2;PLA2G2D;DGAT1;...
|
| Drug metabolism |
-1.57 |
2.93e-1 |
78/151 (51.66%) |
CMPK1;MAOA;GSTT1;...
|
| Pentose and glucuronate interconversions |
-1.58 |
3.33e-1 |
17/34 (50%) |
GUSB;UGT2B4;UGDH;...
|
| Mineral absorption |
-1.65 |
3.24e-1 |
48/60 (80%) |
VDR;SLC26A6;MT1HL1;...
|
| Glycerolipid metabolism |
-1.72 |
2.73e-1 |
44/61 (72.13%) |
DGAT1;LIPF;AGPAT2;...
|
| Other glycan degradation |
-1.83 |
2.13e-1 |
13/18 (72.22%) |
NEU1;MANBA;MAN2B2;...
|
