Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMP4DLV)

• Drug Name: 1,2,3,4-Tetrahydro-naphthalen-2-ylamine Drug Info
• Synonyms: 1,2,3,4-tetrahydronaphthalen-2-amine; 2954-50-9; 1,2,3,4-Tetrahydro-2-naphthylamine; 2-Aminotetralin; 2-Naphthalenamine, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydro-2-naphthalenamine; CHEMBL30294; LCGFVWKNXLRFIF-UHFFFAOYSA-N; 617700-25-1; 2-1,2,3,4-tetrahydronaphthylamine; 2-amino-tetralin; tetralin-2-amine; ACMC-20ac6z; AC1Q53DS; AC1L1S2C; SCHEMBL42952; .beta.-tetrahydronaphthylamine; BDBM23981; Tetrahydronaphthalen-2-amine, 3a; MolPort-001-779-767
• Cross-matching ID:
  PubChem CID: 34677
  ChEBI ID: CHEMBL30294
  CAS Number: CAS 2954-50-9
  TTD Drug ID: D08HOJ

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Primary immunodeficiency	2.07	0.00e+0	33/38 (86.84%)	CD8A;IL2RG;CD3D;...
Viral protein interaction with cytokine and cytokine re...	1.98	1.02e-2	84/100 (84%)	CXCL13;CXCL9;CCL19;...
Complement and coagulation cascades	-1.86	2.61e-2	76/85 (89.41%)	A2M;C2;PLG;...
Vibrio cholerae infection	-1.94	9.78e-3	44/50 (88%)	SEC61B;SEC61A1;SEC61G;...
Folate biosynthesis	-2.06	0.00e+0	23/26 (88.46%)	DHFR;FPGS;TH;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast

Nasopharyngeal carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
FIBRNPC	CVCL_UK07	Homo sapiens	10uM	6H, 24H	Hide ▲