Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMQXLF3)

• Drug Name: Cefsulodin Drug Info
• Synonyms: cefsulodin; (6R,7R)-3-{[4-(aminocarbonyl)pyridinium-1-yl]methyl}-8-oxo-7-{[phenyl(sulfo)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; AC1NR4MP; SCHEMBL65524; DTXSID6022769; Cefsulodin free acid (SCE-129), Antibiotic for Culture Media Use Only
• Cross-matching ID:
  PubChem CID: 656575
  ChEBI ID: CHEMBL3351077
  CAS Number: CAS 62587-73-9
  TTD Drug ID: D0XQ0Q
  VARIDT Drug ID: DR00704

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Glycerolipid metabolism	-1.77	4.92e-2	44/61 (72.13%)	GLA;ALDH9A1;DGKG;...
IL-17 signaling pathway	-1.79	4.10e-2	84/94 (89.36%)	IFNG;S100A7;MMP1;...
Mineral absorption	-2.08	0.00e+0	48/60 (80%)	ATP1B3;ATP1A2;ATP1A1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Hide ▲