Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMSDH3A)

• Drug Name: CCT244747 Drug Info
• Synonyms: compound 26 [PMID 23082860]
• Cross-matching ID:
  PubChem CID: 54758482
  ChEBI ID: CHEMBL2203843
  TTD Drug ID: D0Z8PT

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
p53 signaling pathway	1.97	1.12e-2	63/73 (86.3%)	DDB2;CDKN1A;SERPINB5;...
Oxidative phosphorylation	1.97	5.58e-3	93/133 (69.92%)	NDUFB1;ATP5F1E;NDUFA4;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	1.11uM - 10uM	24H	Hide ▲

Skin

Melanoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A-375	CVCL_0132	Homo sapiens	1.11uM - 10uM	24H	Hide ▲