Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMSHW2E)

• Drug Name: [3H]thiamine Drug Info
• Synonyms: thiamin; Aneurin; Antiberiberi factor; Thiadoxine; Betaxin; thiaminium; Vitaneuron; Biamine; Bequin; Bewon; Thiamine ion; thiamine(1+) ion; thiamine(1+); Clotiamina; Bethiazine; Vinothiam; Tiaminal; Thiaminal; Metabolin; Eskaphen; Bithiamin; Tiamidon; Thiavit; Benerva; Begiolan; Thiamol; Bivatin; Bevitine; Beatine; Slowten; Eskapen; Bevitex; Biuno; Berin; Bivita; Beuion; Bedome; Hybee; Apate drops; Lixa-beta; Vetalin S; Thiamin dichloride; [3H]-thiamine; [3H]vitamin B1
• Cross-matching ID:
  PubChem CID: 1130
  ChEBI ID: CHEMBL1547
  CAS Number: CAS 70-16-6
  TTD Drug ID: D07TYL
  VARIDT Drug ID: DR01129

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Ribosome	1.95	1.74e-2	113/158 (71.52%)	MRPS16;RPL26L1;RPL36;...
Protein digestion and absorption	-1.98	2.21e-2	78/103 (75.73%)	SLC1A1;COL9A1;XPNPEP2;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Hide ▲