Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMTAJP7)

• Drug Name: Butanoic Acid Drug Info
• Synonyms: butyric acid; butanoic acid; n-Butyric acid; 107-92-6; n-Butanoic acid; propylformic acid; ethylacetic acid; 1-propanecarboxylic acid; Butanic acid; butyrate; 1-Butyric acid; Buttersaeure; butanoate; Kyselina maselna; Butyric acid (natural); Propanecarboxylic acid; Buttersaeure [German]; 1-butanoic acid; FEMA Number 2221; Kyselina maselna [Czech]; FEMA No. 2221; CCRIS 6552; HSDB 940; butoic acid; Ethyacetic Acid; 2-butanoate; NSC 8415; UNII-40UIR9Q29H; UN2820; AI3-15306; EINECS 203-532-3; BRN 0906770; CH3-[CH2]2-COOH; 40UIR9Q29H
• Cross-matching ID:
  PubChem CID: 264
  ChEBI ID: CHEMBL14227
  CAS Number: CAS 107-92-6
  TTD Drug ID: D0T4JQ
  VARIDT Drug ID: DR01475

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Mineral absorption	-1.82	4.54e-2	48/60 (80%)	ATP2B1;SLC5A1;MT2A;...
PPAR signaling pathway	-2.03	0.00e+0	66/74 (89.19%)	PLIN1;PLTP;CD36;...
Steroid biosynthesis	-2.10	0.00e+0	19/20 (95%)	SQLE;CYP27B1;HSD17B7;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	0.04uM - 10uM	24H	Hide ▲

Colon

Colorectal adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HT-29	CVCL_0320	Homo sapiens	0.37uM - 50uM	2H, 24H	Hide ▲

Peripheral blood

Acute myeloid leukemia

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HL-60	CVCL_0002	Homo sapiens	0.37uM - 50uM	2H, 24H	Show ▼