| Thiamine metabolism |
1.77 |
1.33e-1 |
12/15 (80%) |
AK1;AK4;TPK1;...
|
| Glutathione metabolism |
1.76 |
8.45e-2 |
43/57 (75.44%) |
GSTT1;CHAC1;GSTP1;...
|
| Salivary secretion |
1.74 |
7.71e-2 |
76/93 (81.72%) |
STATH;FXYD2;CALML3;...
|
| Mineral absorption |
1.70 |
9.12e-2 |
48/60 (80%) |
MT1F;MT1M;MT1E;...
|
| Pancreatic secretion |
1.67 |
1.07e-1 |
87/102 (85.29%) |
CA2;ATP2A3;FXYD2;...
|
| Base excision repair |
1.67 |
9.04e-2 |
29/33 (87.88%) |
POLE3;POLE2;FEN1;...
|
| Nitrogen metabolism |
1.62 |
1.27e-1 |
16/17 (94.12%) |
CA2;CPS1;CA12;...
|
| Arachidonic acid metabolism |
1.58 |
1.59e-1 |
48/61 (78.69%) |
PTGIS;GPX1;PLAAT3;...
|
| PPAR signaling pathway |
1.53 |
2.27e-1 |
66/74 (89.19%) |
FABP4;PLIN1;ADIPOQ;...
|
| Glycerolipid metabolism |
1.43 |
4.47e-1 |
44/61 (72.13%) |
PLPP3;AKR1A1;MGLL;...
|
| Primary bile acid biosynthesis |
1.41 |
4.63e-1 |
15/17 (88.24%) |
CYP27A1;SLC27A5;ACOX2;...
|
| Amino sugar and nucleotide sugar metabolism |
1.41 |
4.27e-1 |
38/48 (79.17%) |
PMM2;CYB5R2;UGP2;...
|
| Linoleic acid metabolism |
1.41 |
4.01e-1 |
21/29 (72.41%) |
PLAAT3;PLA2G4A;PLA2G12A;...
|
| Mannose type O-glycan biosynthesis |
1.41 |
3.74e-1 |
14/23 (60.87%) |
RXYLT1;B4GAT1;B4GALT3;...
|
| Carbohydrate digestion and absorption |
1.39 |
3.93e-1 |
37/47 (78.72%) |
FXYD2;ATP1A2;CACNA1D;...
|
| Proximal tubule bicarbonate reclamation |
1.39 |
3.77e-1 |
21/23 (91.3%) |
CA2;FXYD2;ATP1A2;...
|
| Protein export |
1.39 |
3.60e-1 |
17/23 (73.91%) |
OXA1L;HSPA5;SRPRB;...
|
| Fanconi anemia pathway |
1.38 |
3.66e-1 |
36/54 (66.67%) |
FANCI;RAD51;POLI;...
|
| Neutrophil extracellular trap formation |
1.37 |
3.73e-1 |
101/189 (53.44%) |
TLR4;MAPK13;CLCN3;...
|
| Arginine biosynthesis |
1.35 |
4.10e-1 |
17/22 (77.27%) |
CPS1;ASS1;ASL;...
|
| Gastric acid secretion |
1.32 |
4.72e-1 |
63/76 (82.89%) |
CA2;CALML3;ATP1A2;...
|
| Purine metabolism |
1.32 |
4.70e-1 |
102/129 (79.07%) |
PDE4B;AK1;AK4;...
|
| Synthesis and degradation of ketone bodies |
1.31 |
4.65e-1 |
9/10 (90%) |
HMGCS2;BDH1;BDH2;...
|
| Regulation of lipolysis in adipocytes |
1.31 |
4.60e-1 |
52/55 (94.55%) |
IRS2;FABP4;PLIN1;...
|
| DNA replication |
1.29 |
5.13e-1 |
34/36 (94.44%) |
POLE3;POLE2;MCM2;...
|
| Drug metabolism |
1.28 |
5.05e-1 |
78/151 (51.66%) |
GSTT1;GSTP1;CES2;...
|
| Pyrimidine metabolism |
1.26 |
5.12e-1 |
40/56 (71.43%) |
TYMP;CANT1;UMPS;...
|
| Ether lipid metabolism |
1.26 |
5.12e-1 |
32/49 (65.31%) |
PLPP3;PLA2G7;ENPP2;...
|
| Morphine addiction |
1.26 |
5.04e-1 |
80/91 (87.91%) |
PDE4B;CACNA1A;PDE2A;...
|
| Serotonergic synapse |
1.24 |
5.12e-1 |
97/114 (85.09%) |
CACNA1A;GNAQ;CACNA1D;...
|
| Hepatocellular carcinoma |
-1.34 |
3.73e-1 |
135/168 (80.36%) |
NRAS;SMARCC2;PTEN;...
|
| Small cell lung cancer |
-1.35 |
3.66e-1 |
90/92 (97.83%) |
PIK3CB;MAX;CKS2;...
|
| Steroid hormone biosynthesis |
-1.36 |
3.52e-1 |
43/61 (70.49%) |
CYP3A7;HSD17B1;CYP3A5;...
|
| Renal cell carcinoma |
-1.37 |
3.44e-1 |
68/69 (98.55%) |
EPAS1;FH;HIF1A;...
|
| Regulation of actin cytoskeleton |
-1.37 |
3.56e-1 |
185/218 (84.86%) |
ITGA8;PPP1R12B;PIKFYVE;...
|
| Chronic myeloid leukemia |
-1.37 |
3.69e-1 |
72/76 (94.74%) |
GADD45B;BAD;RELA;...
|
| Bacterial invasion of epithelial cells |
-1.38 |
3.54e-1 |
59/77 (76.62%) |
CTNNA1;DNM2;CLTC;...
|
| TNF signaling pathway |
-1.38 |
3.65e-1 |
103/112 (91.96%) |
NOD2;MAP3K7;EDN1;...
|
| Huntington disease |
-1.39 |
3.47e-1 |
233/306 (76.14%) |
ATG2B;ATP5PB;CREB5;...
|
| Salmonella infection |
-1.41 |
3.30e-1 |
198/249 (79.52%) |
DYNC1LI1;AHNAK2;MAPK14;...
|
| Parkinson disease |
-1.41 |
3.44e-1 |
176/249 (70.68%) |
ITPR3;MAPK10;COX7A2L;...
|
| Hippo signaling pathway |
-1.41 |
3.47e-1 |
120/186 (64.52%) |
ID1;PPP2R2D;BMPR2;...
|
| Proteoglycans in cancer |
-1.42 |
3.51e-1 |
172/205 (83.9%) |
MAP2K2;SOS2;KDR;...
|
| Ubiquinone and other terpenoid-quinone biosynthesis |
-1.43 |
3.42e-1 |
9/11 (81.82%) |
GGCX;HPD;COQ6;...
|
| Diabetic cardiomyopathy |
-1.43 |
3.46e-1 |
162/203 (79.8%) |
NDUFA4L2;COX6C;NDUFA1;...
|
| Folate biosynthesis |
-1.43 |
3.61e-1 |
23/26 (88.46%) |
GPHN;GCH1;GGH;...
|
| Relaxin signaling pathway |
-1.45 |
3.31e-1 |
114/129 (88.37%) |
PRKACA;GNG7;GNG11;...
|
| AGE-RAGE signaling pathway in diabetic complications |
-1.49 |
2.60e-1 |
97/100 (97%) |
RELA;CCND1;HRAS;...
|
| Proteasome |
-1.50 |
2.61e-1 |
44/46 (95.65%) |
PSMC1;PSMB2;PSMA6;...
|
| Amoebiasis |
-1.51 |
2.60e-1 |
99/102 (97.06%) |
SERPINB3;CXCL1;COL4A4;...
|
| Non-small cell lung cancer |
-1.52 |
2.67e-1 |
70/72 (97.22%) |
RARB;GADD45B;MET;...
|
| Complement and coagulation cascades |
-1.52 |
2.94e-1 |
76/85 (89.41%) |
CFB;PLAT;SERPINC1;...
|
| Legionellosis |
-1.53 |
2.92e-1 |
51/57 (89.47%) |
HSPA6;CASP3;HSPD1;...
|
| Prion disease |
-1.54 |
3.01e-1 |
209/273 (76.56%) |
NDUFS4;CAV3;PIK3CB;...
|
| Colorectal cancer |
-1.54 |
3.42e-1 |
84/86 (97.67%) |
CASP3;RALA;AKT3;...
|
| Bladder cancer |
-1.64 |
1.73e-1 |
40/41 (97.56%) |
DAPK1;NRAS;MAP2K2;...
|
| Focal adhesion |
-1.64 |
1.92e-1 |
180/201 (89.55%) |
COL4A2;PAK6;PPP1CC;...
|
| Melanoma |
-1.67 |
1.71e-1 |
68/72 (94.44%) |
GADD45B;MET;BAD;...
|
| Breast cancer |
-1.68 |
2.24e-1 |
119/147 (80.95%) |
NRAS;PTEN;JAG2;...
|
| Circadian rhythm |
-1.72 |
1.88e-1 |
26/31 (83.87%) |
RORA;CSNK1E;RORB;...
|
