Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMTOUY9)

Drug Name
Suramin Drug Info
Synonyms
Antrypol; Belganyl; Farma; Fourneau; Germanin; Moranyl; Naganil; Naganin; Naganine; Naganol; Naphuride; SVR; Suramine; SURAMIN SODIUM; Sodium suramin; Suramine sodium; Farma 939; Naganol 6 Na; Germanin (TN); SGCTO-001
Therapeutic ClassAntinematodal Agents
Cross-matching ID
PubChem CID
5361
ChEBI ID
CHEMBL45906
CAS Number
CAS 145-63-1
TTD Drug ID
D0H2UB

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Nitrogen metabolism -1.79 3.35e-2 16/17 (94.12%) CA8;CA4;CA12;...
Other glycan degradation -1.82 3.14e-2 13/18 (72.22%) NEU1;FUCA1;MAN2C1;...
Collecting duct acid secretion -1.85 2.79e-2 22/27 (81.48%) ATP6V1A;ATP6V1B2;ATP6V1F;...
Synaptic vesicle cycle -2.01 5.24e-3 63/78 (80.77%) AP2M1;ATP6V1A;ATP6V0B;...
Porphyrin and chlorophyll metabolism -2.04 1.05e-2 23/43 (53.49%) HCCS;UGT2B15;BLVRB;...
×

Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast
Nasopharyngeal carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
FIBRNPC CVCL_UK07 Homo sapiens 10uM 6H, 24H
Liver
Hepatocellular carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HuH-7 CVCL_0336 Homo sapiens 2.5uM 72H