| Hedgehog signaling pathway |
1.81 |
8.15e-2 |
43/56 (76.79%) |
SCUBE2;GAS1;GRK3;...
|
| Notch signaling pathway |
1.72 |
1.26e-1 |
49/59 (83.05%) |
NOTCH2;DVL1;KAT2A;...
|
| Spliceosome |
1.58 |
3.75e-1 |
101/150 (67.33%) |
HNRNPA1;LSM5;HSPA1A;...
|
| One carbon pool by folate |
1.57 |
3.01e-1 |
15/20 (75%) |
MTR;MTHFD1;SHMT1;...
|
| RNA degradation |
1.55 |
2.72e-1 |
53/79 (67.09%) |
EXOSC10;LSM5;ENO3;...
|
| Ribosome biogenesis in eukaryotes |
1.55 |
2.32e-1 |
52/108 (48.15%) |
NVL;HEATR1;GNL2;...
|
| Legionellosis |
1.54 |
2.18e-1 |
51/57 (89.47%) |
CXCL2;CXCL3;EEF1A2;...
|
| Ubiquitin mediated proteolysis |
1.51 |
2.49e-1 |
87/140 (62.14%) |
STUB1;CDC16;PRPF19;...
|
| Viral protein interaction with cytokine and cytokine re... |
1.45 |
3.67e-1 |
84/100 (84%) |
CXCL2;CXCL14;CXCL3;...
|
| Homologous recombination |
1.42 |
4.15e-1 |
35/41 (85.37%) |
RAD54L;POLD1;POLD2;...
|
| RNA transport |
1.41 |
4.07e-1 |
128/186 (68.82%) |
ELAC2;TARDBP;EIF3B;...
|
| Cysteine and methionine metabolism |
1.40 |
3.98e-1 |
43/50 (86%) |
SRM;MAT2A;MTR;...
|
| Thyroid hormone signaling pathway |
1.38 |
4.13e-1 |
112/121 (92.56%) |
ESR1;NOTCH2;KAT2A;...
|
| AMPK signaling pathway |
1.36 |
4.31e-1 |
106/120 (88.33%) |
IGF1;FASN;IGF1R;...
|
| Breast cancer |
1.33 |
5.01e-1 |
119/147 (80.95%) |
IGF1;ESR1;FZD10;...
|
| Cell cycle |
1.32 |
5.11e-1 |
110/124 (88.71%) |
CDC16;SMC1A;TGFB3;...
|
| Aminoacyl-tRNA biosynthesis |
1.32 |
4.87e-1 |
15/66 (22.73%) |
CARS2;FARSA;LARS2;...
|
| Non-homologous end-joining |
1.31 |
4.75e-1 |
11/13 (84.62%) |
PRKDC;FEN1;POLM
|
| Protein digestion and absorption |
1.31 |
4.67e-1 |
78/103 (75.73%) |
COL16A1;SLC7A8;COL9A2;...
|
| Rheumatoid arthritis |
1.30 |
4.61e-1 |
78/93 (83.87%) |
CXCL2;CXCL3;HLA-DQA1;...
|
| Fanconi anemia pathway |
1.29 |
4.79e-1 |
36/54 (66.67%) |
MUS81;FAAP100;RAD51C;...
|
| Arginine and proline metabolism |
1.28 |
4.85e-1 |
39/50 (78%) |
SRM;ARG2;MAOA;...
|
| NOD-like receptor signaling pathway |
1.27 |
4.82e-1 |
145/181 (80.11%) |
CXCL2;OAS1;CXCL3;...
|
| Insulin signaling pathway |
1.26 |
5.11e-1 |
121/137 (88.32%) |
FASN;EXOC7;TSC2;...
|
| Prostate cancer |
1.25 |
5.07e-1 |
93/97 (95.88%) |
IGF1;KLK3;IGF1R;...
|
| Kaposi sarcoma-associated herpesvirus infection |
1.24 |
5.25e-1 |
172/193 (89.12%) |
CXCL2;CXCL3;ITPR3;...
|
| mRNA surveillance pathway |
1.23 |
5.48e-1 |
71/98 (72.45%) |
TARDBP;CPSF7;NXF1;...
|
| Herpes simplex virus 1 infection |
1.23 |
5.29e-1 |
165/498 (33.13%) |
BST2;OAS1;HLA-DQA1;...
|
| Amoebiasis |
1.22 |
5.28e-1 |
99/102 (97.06%) |
CXCL2;CXCL3;ARG2;...
|
| HIF-1 signaling pathway |
1.22 |
5.17e-1 |
105/109 (96.33%) |
IGF1;TIMP1;ENO3;...
|
| Fc gamma R-mediated phagocytosis |
-1.42 |
2.21e-1 |
79/97 (81.44%) |
HCK;ARPC2;GSN;...
|
| Parkinson disease |
-1.42 |
2.22e-1 |
176/249 (70.68%) |
COX5B;NDUFA4;NDUFA8;...
|
| Melanogenesis |
-1.42 |
2.21e-1 |
74/101 (73.27%) |
EDN1;FZD7;TCF7L2;...
|
| Gastric acid secretion |
-1.47 |
1.97e-1 |
63/76 (82.89%) |
ADCY2;ADCY6;GNAS;...
|
| Nitrogen metabolism |
-1.47 |
2.00e-1 |
16/17 (94.12%) |
CA9;GLUD1;CA4;...
|
| GABAergic synapse |
-1.47 |
2.08e-1 |
76/89 (85.39%) |
GNG10;GNG11;GAD1;...
|
| Pancreatic secretion |
-1.47 |
2.10e-1 |
87/102 (85.29%) |
CPB1;CHRM3;RAP1B;...
|
| Tight junction |
-1.48 |
2.11e-1 |
130/169 (76.92%) |
MYL6;HCLS1;RAP2C;...
|
| Glutathione metabolism |
-1.48 |
2.04e-1 |
43/57 (75.44%) |
RRM2;G6PD;GPX1;...
|
| Fluid shear stress and atherosclerosis |
-1.49 |
2.04e-1 |
123/139 (88.49%) |
MAP2K5;GSTM4;PRKAA1;...
|
| Steroid hormone biosynthesis |
-1.51 |
1.76e-1 |
43/61 (70.49%) |
HSD3B1;HSD17B3;SRD5A3;...
|
| Drug metabolism |
-1.52 |
1.72e-1 |
78/151 (51.66%) |
CYP3A4;HPRT1;NME7;...
|
| Steroid biosynthesis |
-1.55 |
1.38e-1 |
19/20 (95%) |
CYP24A1;LIPA;DHCR7;...
|
| Porphyrin and chlorophyll metabolism |
-1.58 |
1.11e-1 |
23/43 (53.49%) |
CP;COX15;UGT2B28;...
|
| Tyrosine metabolism |
-1.61 |
9.38e-2 |
30/36 (83.33%) |
AOX1;MAOB;GSTZ1;...
|
| Oxidative phosphorylation |
-1.62 |
8.64e-2 |
93/133 (69.92%) |
ATP6V0E1;ATP5MF;ATP6V1B1;...
|
| Nicotine addiction |
-1.62 |
9.09e-2 |
32/40 (80%) |
GRIA1;SLC17A7;GABRB1;...
|
| Renin secretion |
-1.62 |
8.83e-2 |
61/69 (88.41%) |
EDN1;PPP3R1;EDN3;...
|
| Proximal tubule bicarbonate reclamation |
-1.63 |
9.28e-2 |
21/23 (91.3%) |
GLUD1;CA4;PCK1;...
|
| Platelet activation |
-1.63 |
1.01e-1 |
106/124 (85.48%) |
RAP1B;SRC;PPP1CA;...
|
| Ferroptosis |
-1.64 |
9.78e-2 |
36/41 (87.8%) |
FTL;ACSL4;GCLM;...
|
| Pathogenic Escherichia coli infection |
-1.68 |
7.20e-2 |
152/197 (77.16%) |
CLDN16;MYO1D;MAP3K7;...
|
| Gap junction |
-1.69 |
7.67e-2 |
72/88 (81.82%) |
CDK1;PDGFC;ADCY3;...
|
| Metabolism of xenobiotics by cytochrome P450 |
-1.69 |
8.61e-2 |
49/77 (63.64%) |
CYP2F1;CYP3A4;EPHX1;...
|
| Staphylococcus aureus infection |
-1.70 |
8.53e-2 |
72/95 (75.79%) |
C1QA;FPR1;HLA-DQB1;...
|
| Estrogen signaling pathway |
-1.71 |
9.32e-2 |
119/137 (86.86%) |
PRKCD;SHC1;HSP90AB1;...
|
| Neutrophil extracellular trap formation |
-1.71 |
1.11e-1 |
101/189 (53.44%) |
ATG7;PADI4;MAP3K7;...
|
| Collecting duct acid secretion |
-1.72 |
1.40e-1 |
22/27 (81.48%) |
ATP6V0E1;ATP6V1B1;SLC12A7;...
|
| Leukocyte transendothelial migration |
-1.80 |
5.12e-2 |
90/114 (78.95%) |
PLCG2;RAPGEF4;CLDN18;...
|
| Retinol metabolism |
-1.83 |
6.82e-2 |
41/68 (60.29%) |
UGT2B28;AOX1;UGT2A3;...
|
