Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMU6FOG)

Drug Name
Clorsulon Drug Info
Synonyms
CLORSULON; 60200-06-8; Curatrem; Clorsulonum [Latin]; Clorsulone [French]; Clorsulon [Spanish]; UNII-EG1ZDO6LRD; EG1ZDO6LRD; EINECS 262-100-2; MK 401; MK-401; BRN 2821757; 4-amino-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide; 4-Amino-6-(trichlorovinyl)-m-benzenedisulfonamide; L 631529; L-631,529; 4-Amino-6-(trichlorovinyl)-1,3-benzenedisulfonamide; 4-Amino-6-(trichloroethenyl)-1,3-benzenedisulfonamide; 1,3-Benzenedisulfonamide, 4-amino-6-(trichloroethenyl)-; NCGC00016893-01; NCGC00182084-01
Cross-matching ID
PubChem CID
43231
ChEBI ID
CHEMBL94811
CAS Number
CAS 60200-06-8
TTD Drug ID
D0V6EH

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
IL-17 signaling pathway 2.48 0.00e+0 84/94 (89.36%) CXCL1;CCL20;CXCL8;...
TNF signaling pathway 2.42 0.00e+0 103/112 (91.96%) CXCL1;CCL20;CXCL5;...
NF-kappa B signaling pathway 2.29 0.00e+0 90/104 (86.54%) CXCL1;CXCL8;BCL2A1;...
Rheumatoid arthritis 2.21 0.00e+0 78/93 (83.87%) CXCL1;CCL20;CXCL8;...
Legionellosis 1.96 0.00e+0 51/57 (89.47%) CXCL1;CXCL8;CXCL3;...
Epithelial cell signaling in Helicobacter pylori infect... 1.74 3.58e-2 62/70 (88.57%) CXCL1;CXCL8;CXCL3;...
Hematopoietic cell lineage 1.73 3.46e-2 90/99 (90.91%) IL1R1;IL1R2;KIT;...
Proximal tubule bicarbonate reclamation -1.84 1.76e-2 21/23 (91.3%) PCK2;PCK1;CA2;...
Complement and coagulation cascades -2.13 0.00e+0 76/85 (89.41%) CFHR2;PLAUR;C8B;...
Mineral absorption -2.16 0.00e+0 48/60 (80%) SLC39A4;HEPH;HMOX2;...
×

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H