Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMU6OFP)

• Drug Name: Dyclonine Drug Info
• Synonyms: Diclonia; Diclonina; Dyclocaine; Dyclocainum; Dyclonin; Dycloninum; Dyclothane; Tanaclone; Diclonina [INN-Spanish]; Dyclonine (INN); Dyclonine [INN:BAN]; Dycloninum [INN-Latin]; 1-(4-Butoxy-phenyl)-3-piperidin-1-yl-propan-1-one; 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone; 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one; 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one; 1-Propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)-(9CI); 2-(1-piperidyl)ethyl p-butoxyphenyl ketone; 3-Piperidino-4'-butoxypropiophenone; 4'-Butoxy-3-piperidinopropiophenone; 4-butoxy-beta-piperidinopropiophenone; 4-n-butoxy-beta-(1-piperidyl)propiophenone
• Therapeutic Class: Anesthetics
• Cross-matching ID:
  PubChem CID: 3180
  ChEBI ID: CHEMBL1201217
  CAS Number: CAS 586-60-7
  TTD Drug ID: D04QLR

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Measles	-1.82	3.30e-2	133/139 (95.68%)	IRAK4;MYD88;TP53;...
Rheumatoid arthritis	-1.82	4.96e-2	78/93 (83.87%)	TNFSF11;ATP6V1F;ANGPT1;...
NF-kappa B signaling pathway	-1.95	0.00e+0	90/104 (86.54%)	NFKBIA;TNFSF14;TNFSF11;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	24H	Hide ▲