Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMU6ZMX)

Drug Name
Carmoxirole Drug Info
Synonyms Carmoxirole hydrochloride; EMD-45609
Cross-matching ID
PubChem CID
57364
ChEBI ID
CHEMBL64200
CAS Number
CAS 98323-83-2
TTD Drug ID
D0K2PS

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Cell cycle 1.87 1.36e-2 110/124 (88.71%) SMC1A;STAG2;ABL1;...
Circadian rhythm 1.81 2.04e-2 26/31 (83.87%) SKP1;RBX1;PRKAG1;...
Cocaine addiction -1.85 2.31e-2 42/49 (85.71%) SLC6A3;GNAI2;ATF4;...
Valine, leucine and isoleucine degradation -1.86 3.47e-2 42/48 (87.5%) HMGCL;ACADS;AOX1;...
Ascorbate and aldarate metabolism -2.03 0.00e+0 15/30 (50%) ALDH1B1;AKR1A1;UGT2B4;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H
Hematopoietic system
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
ASC CVCL_U602 Homo sapiens 10uM 24H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H, 24H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 10uM 6H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Non-small cell lung carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HCC515 CVCL_5134 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H