Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMUB0EJ)

Drug Name
Pyrazolo[1,5-a]pyrimidine 3G Drug Info
Synonyms KDR/Flk-1 kinase inhibitor IV; pyrazolo[1,5-a]pyrimidine 3g
Cross-matching ID
PubChem CID
5329468
ChEBI ID
CHEMBL92461
CAS Number
CAS 216661-57-3
TTD Drug ID
D09LKM

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Systemic lupus erythematosus 2.08 2.12e-2 45/135 (33.33%) HLA-DQA1;CTSG;HLA-DRA;...
Phenylalanine metabolism 1.95 2.65e-2 14/17 (82.35%) MAOB;HPD;MAOA;...
Protein digestion and absorption -1.96 1.89e-2 78/103 (75.73%) CELA3B;SLC16A10;MEP1A;...
×

Pharmacogenomic Perturbation Across Diseases and Tissues

Bone
Osteosarcoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
U-2 OS CVCL_0042 Homo sapiens 10uM 6H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H, 24H
Lung
Non-small cell lung carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HCC515 CVCL_5134 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H