Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMUFGAY)

• Drug Name: Betazole Drug Info
• Synonyms: Ametazole; Betazol; Betazolo; Betazolum; Betazole [INN]; Betazolo [DCIT]; Lilly 96791; Betazol [INN-Spanish]; Betazolum [INN-Latin]; 1H-Pyrazole-3-ethanamine; 2-(1H-Pyrazol-3-yl)ethanamine; 2-(1H-pyrazol-5-yl)ethanamine; 2-(3-Pyrazolyl)ethylamine; 3-(2-Aminoethyl)pyrazole; 3-(beta-aminoethyl)pyrazole
• Therapeutic Class: Antihistamines
• Cross-matching ID:
  PubChem CID: 7741
  ChEBI ID: CHEMBL59170
  CAS Number: CAS 105-20-4
  TTD Drug ID: D01OUE

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
PPAR signaling pathway	2.21	0.00e+0	66/74 (89.19%)	CD36;FABP1;FABP4;...
Retinol metabolism	1.97	1.33e-2	41/68 (60.29%)	ADH1B;AOX1;UGT2B4;...
Fat digestion and absorption	1.93	8.89e-3	35/43 (81.4%)	PLA2G2A;CD36;FABP1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Kidney

Normal (Transformed)

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HEK293T	CVCL_0063	Homo sapiens	0.125uM - 10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	24H	Show ▼

Skin

Melanoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A-375	CVCL_0132	Homo sapiens	0.125uM - 10uM	6H, 24H	Show ▼