Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMUOQZD)

Drug Name
Arachidonic Acid Drug Info
Synonyms
arachidonic acid; 506-32-1; arachidonate; (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid; Immunocytophyte; (all-Z)-5,8,11,14-Eicosatetraenoic acid; cis-5,8,11,14-Eicosatetraenoic acid; 5,8,11,14-Eicosatetraenoic acid, (all-Z)-; 5Z,8Z,11Z,14Z-eicosatetraenoic acid; UNII-27YG812J1I; all-cis-5,8,11,14-eicosatetraenoic acid; Arachidonic Acid, 99%; CHEMBL15594; CHEBI:15843; YZXBAPSDXZZRGB-DOFZRALJSA-N; 27YG812J1I; cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic acid; (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid
Cross-matching ID
PubChem CID
444899
ChEBI ID
CHEMBL15594
CAS Number
CAS 506-32-1
TTD Drug ID
D0HD9P
INTEDE Drug ID
DR0129

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Cell cycle 2.01 2.33e-2 110/124 (88.71%) CCNA2;PCNA;CCNB1;...
Amino sugar and nucleotide sugar metabolism -1.72 4.38e-2 38/48 (79.17%) GALE;HEXB;GALK1;...
Pentose and glucuronate interconversions -1.74 3.63e-2 17/34 (50%) UGP2;CRYL1;KL;...
Butanoate metabolism -1.77 3.23e-2 23/28 (82.14%) HMGCS2;ALDH5A1;ECHS1;...
Other glycan degradation -1.80 2.82e-2 13/18 (72.22%) HEXB;MAN2C1;AGA;...
Fructose and mannose metabolism -1.82 2.69e-2 30/33 (90.91%) ALDOA;MPI;PMM2;...
Protein digestion and absorption -1.96 1.61e-2 78/103 (75.73%) COL9A3;COL2A1;ATP1B2;...
Protein processing in endoplasmic reticulum -2.01 1.61e-2 127/171 (74.27%) VCP;DNAJB2;PRKCSH;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Bone
Osteosarcoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
U-2 OS CVCL_0042 Homo sapiens 1.11uM 6H