| Tyrosine metabolism |
2.27 |
0.00e+0 |
30/36 (83.33%) |
HGD;MAOA;ADH1B;...
|
| Tryptophan metabolism |
2.25 |
0.00e+0 |
35/42 (83.33%) |
ACAT1;MAOA;HADH;...
|
| Peroxisome |
2.14 |
0.00e+0 |
72/82 (87.8%) |
MPV17;IDH1;ACSL4;...
|
| Fatty acid degradation |
2.13 |
0.00e+0 |
40/43 (93.02%) |
ACAT1;ADH1B;HADH;...
|
| Steroid hormone biosynthesis |
2.13 |
0.00e+0 |
43/61 (70.49%) |
AKR1C3;UGT2B28;AKR1C1;...
|
| Oxidative phosphorylation |
2.08 |
0.00e+0 |
93/133 (69.92%) |
PPA1;PPA2;ATP6V0E2;...
|
| Citrate cycle (TCA cycle) |
2.08 |
0.00e+0 |
30/30 (100%) |
IDH1;OGDH;IDH3A;...
|
| Valine, leucine and isoleucine degradation |
2.07 |
0.00e+0 |
42/48 (87.5%) |
HMGCS1;ACAT1;HADH;...
|
| Terpenoid backbone biosynthesis |
2.05 |
1.05e-3 |
18/22 (81.82%) |
HMGCS1;IDI1;ACAT1;...
|
| Drug metabolism |
2.04 |
9.43e-4 |
78/151 (51.66%) |
UGT2B28;MAOA;ADH1B;...
|
| Complement and coagulation cascades |
2.03 |
8.57e-4 |
76/85 (89.41%) |
CLU;FGG;CFB;...
|
| Fatty acid biosynthesis |
2.02 |
1.57e-3 |
16/18 (88.89%) |
FASN;ACSL4;ACSL3;...
|
| Pyruvate metabolism |
2.01 |
1.45e-3 |
41/47 (87.23%) |
ACAT1;ADH1B;ACAT2;...
|
| Pentose and glucuronate interconversions |
2.00 |
1.35e-3 |
17/34 (50%) |
AKR1B10;UGT2B28;UGT2B4;...
|
| DNA replication |
1.99 |
1.26e-3 |
34/36 (94.44%) |
RPA2;RFC5;RNASEH2B;...
|
| Ascorbate and aldarate metabolism |
1.99 |
1.18e-3 |
15/30 (50%) |
UGT2B28;UGT2B4;UGT2B15;...
|
| Metabolism of xenobiotics by cytochrome P450 |
1.98 |
1.11e-3 |
49/77 (63.64%) |
UGT2B28;AKR1C1;ADH1B;...
|
| Arachidonic acid metabolism |
1.98 |
1.05e-3 |
48/61 (78.69%) |
GPX3;AKR1C3;PTGS2;...
|
| Mismatch repair |
1.97 |
9.93e-4 |
22/23 (95.65%) |
RPA2;RFC5;POLD1;...
|
| Synthesis and degradation of ketone bodies |
1.96 |
9.43e-4 |
9/10 (90%) |
HMGCS1;ACAT1;BDH1;...
|
| Steroid biosynthesis |
1.94 |
1.35e-3 |
19/20 (95%) |
DHCR7;MSMO1;FDFT1;...
|
| Glutathione metabolism |
1.93 |
1.29e-3 |
43/57 (75.44%) |
GPX3;G6PD;ODC1;...
|
| Butanoate metabolism |
1.92 |
1.23e-3 |
23/28 (82.14%) |
HMGCS1;ACAT1;BDH1;...
|
| Glyoxylate and dicarboxylate metabolism |
1.90 |
1.96e-3 |
23/30 (76.67%) |
ACAT1;SHMT1;ACAT2;...
|
| Folate biosynthesis |
1.88 |
2.26e-3 |
23/26 (88.46%) |
AKR1B10;AKR1C3;GCH1;...
|
| Porphyrin and chlorophyll metabolism |
1.88 |
2.18e-3 |
23/43 (53.49%) |
CP;UGT2B28;BLVRA;...
|
| Propanoate metabolism |
1.86 |
2.10e-3 |
30/34 (88.24%) |
ACAT1;ACAT2;ACSS3;...
|
| Ovarian steroidogenesis |
1.84 |
2.36e-3 |
41/51 (80.39%) |
AKR1C3;PRKACB;IGF1;...
|
| Biosynthesis of unsaturated fatty acids |
1.81 |
2.93e-3 |
21/27 (77.78%) |
SCD;FADS1;ELOVL6;...
|
| Vitamin digestion and absorption |
1.71 |
1.40e-2 |
17/24 (70.83%) |
SCARB1;APOB;TCN2;...
|
| Human papillomavirus infection |
-1.65 |
3.82e-2 |
284/331 (85.8%) |
HLA-E;GNAS;UBE3A;...
|
| Hypertrophic cardiomyopathy |
-1.66 |
4.03e-2 |
81/90 (90%) |
ITGB6;LAMA2;ITGA8;...
|
| PI3K-Akt signaling pathway |
-1.67 |
3.83e-2 |
317/354 (89.55%) |
FGF17;LAMA2;ITGA8;...
|
| Transcriptional misregulation in cancer |
-1.69 |
3.13e-2 |
158/192 (82.29%) |
REL;MPO;NSD2;...
|
| Arrhythmogenic right ventricular cardiomyopathy |
-1.70 |
2.84e-2 |
70/77 (90.91%) |
ITGB6;LAMA2;ITGA8;...
|
| Phospholipase D signaling pathway |
-1.74 |
2.06e-2 |
134/148 (90.54%) |
DNM2;TSC2;RAF1;...
|
| Proteoglycans in cancer |
-1.75 |
1.89e-2 |
172/205 (83.9%) |
RAF1;RRAS;KRAS;...
|
| AGE-RAGE signaling pathway in diabetic complications |
-1.76 |
1.78e-2 |
97/100 (97%) |
STAT3;MAPK8;DIAPH1;...
|
| Adherens junction |
-1.77 |
1.55e-2 |
63/71 (88.73%) |
NLK;LMO7;LEF1;...
|
| Relaxin signaling pathway |
-1.79 |
1.28e-2 |
114/129 (88.37%) |
GNAS;MAPK8;SOS2;...
|
| Prostate cancer |
-1.82 |
5.92e-3 |
93/97 (95.88%) |
LEF1;TCF7L2;HSP90AA1;...
|
| Rap1 signaling pathway |
-1.82 |
6.66e-3 |
184/210 (87.62%) |
KRIT1;RAF1;RRAS;...
|
| Protein digestion and absorption |
-1.84 |
4.57e-3 |
78/103 (75.73%) |
KCNK5;COL13A1;PRSS1;...
|
| TGF-beta signaling pathway |
-1.89 |
3.55e-3 |
81/94 (86.17%) |
PITX2;SKP1;BMP4;...
|
| MicroRNAs in cancer |
-1.92 |
4.26e-3 |
146/310 (47.1%) |
MDM2;PIM1;RAF1;...
|
| Notch signaling pathway |
-1.95 |
2.67e-3 |
49/59 (83.05%) |
HEY2;DVL3;NUMB;...
|
| ECM-receptor interaction |
-2.02 |
3.55e-3 |
80/88 (90.91%) |
HMMR;ITGB6;LAMA2;...
|
| Focal adhesion |
-2.09 |
5.33e-3 |
180/201 (89.55%) |
ITGB5;MAPK8;MYL9;...
|
| Regulation of actin cytoskeleton |
-2.09 |
1.07e-2 |
185/218 (84.86%) |
MYL10;RAF1;ITGAX;...
|
