| Citrate cycle (TCA cycle) |
1.79 |
2.15e-1 |
30/30 (100%) |
IDH2;PC;SUCLG1;...
|
| Proteasome |
1.76 |
2.02e-1 |
44/46 (95.65%) |
PSMB8;PSMA7;PSMB9;...
|
| ECM-receptor interaction |
1.71 |
2.07e-1 |
80/88 (90.91%) |
FN1;TNC;THBS1;...
|
| Measles |
1.68 |
1.96e-1 |
133/139 (95.68%) |
OAS1;MX2;MX1;...
|
| Pyruvate metabolism |
1.65 |
2.28e-1 |
41/47 (87.23%) |
ADH1B;LDHA;ADH5;...
|
| Parkinson disease |
1.65 |
1.92e-1 |
176/249 (70.68%) |
GNAS;MAOB;PSMA7;...
|
| Retinol metabolism |
1.65 |
1.66e-1 |
41/68 (60.29%) |
ALDH1A2;ALDH1A3;ADH1B;...
|
| Vascular smooth muscle contraction |
1.63 |
1.66e-1 |
113/133 (84.96%) |
GNAS;ACTG2;RAMP1;...
|
| Dilated cardiomyopathy |
1.63 |
1.50e-1 |
86/96 (89.58%) |
GNAS;IGF1;SGCG;...
|
| Morphine addiction |
1.62 |
1.39e-1 |
80/91 (87.91%) |
GNAS;GABRP;GABRE;...
|
| DNA replication |
1.62 |
1.26e-1 |
34/36 (94.44%) |
MCM6;MCM3;RPA1;...
|
| Hypertrophic cardiomyopathy |
1.61 |
1.32e-1 |
81/90 (90%) |
IGF1;SGCG;DES;...
|
| Regulation of lipolysis in adipocytes |
1.56 |
1.92e-1 |
52/55 (94.55%) |
GNAS;PTGS2;PLIN1;...
|
| Complement and coagulation cascades |
1.55 |
1.85e-1 |
76/85 (89.41%) |
SERPING1;CFB;F8;...
|
| Prion disease |
1.54 |
1.85e-1 |
209/273 (76.56%) |
PSMA7;ATP5F1E;COX5A;...
|
| Base excision repair |
1.54 |
1.74e-1 |
29/33 (87.88%) |
PCNA;POLE2;HMGB1;...
|
| PPAR signaling pathway |
1.54 |
1.75e-1 |
66/74 (89.19%) |
LPL;SCD5;ADIPOQ;...
|
| Focal adhesion |
1.53 |
1.76e-1 |
180/201 (89.55%) |
FN1;TNC;PDGFC;...
|
| Human papillomavirus infection |
1.50 |
2.12e-1 |
284/331 (85.8%) |
GNAS;PTGS2;FN1;...
|
| RIG-I-like receptor signaling pathway |
1.47 |
2.62e-1 |
64/70 (91.43%) |
ISG15;RNF125;CASP10;...
|
| Progesterone-mediated oocyte maturation |
1.46 |
2.60e-1 |
75/100 (75%) |
IGF1;CCNA2;ADCY7;...
|
| Thermogenesis |
1.46 |
2.57e-1 |
173/232 (74.57%) |
GNAS;PLIN1;ATP5F1E;...
|
| Cardiac muscle contraction |
1.45 |
2.58e-1 |
64/87 (73.56%) |
ATP1A2;CASQ2;COX5A;...
|
| Gap junction |
1.42 |
3.22e-1 |
72/88 (81.82%) |
GNAS;LPAR1;PDGFC;...
|
| Alzheimer disease |
1.42 |
3.11e-1 |
279/369 (75.61%) |
DKK1;LPL;PTGS2;...
|
| Tyrosine metabolism |
1.40 |
3.26e-1 |
30/36 (83.33%) |
ADH1B;ADH5;MAOB;...
|
| HIF-1 signaling pathway |
1.29 |
3.67e-1 |
105/109 (96.33%) |
ANGPT1;LDHA;IGF1;...
|
| Proximal tubule bicarbonate reclamation |
1.29 |
3.60e-1 |
21/23 (91.3%) |
ATP1A2;GLS;AQP1;...
|
| RNA transport |
1.29 |
3.56e-1 |
128/186 (68.82%) |
NUP85;NUP62;NUP93;...
|
| Taurine and hypotaurine metabolism |
1.28 |
3.65e-1 |
8/11 (72.73%) |
CDO1
|
| Lipid and atherosclerosis |
-1.03 |
7.44e-1 |
190/215 (88.37%) |
BID;CXCL1;CASP9;...
|
| Glycine, serine and threonine metabolism |
-1.03 |
7.48e-1 |
31/40 (77.5%) |
AMT;GATM;CBS;...
|
| MAPK signaling pathway |
-1.04 |
7.50e-1 |
272/294 (92.52%) |
GADD45A;PGF;NR4A1;...
|
| Neurotrophin signaling pathway |
-1.17 |
7.34e-1 |
107/119 (89.92%) |
MAP2K5;PDPK1;NFKBIE;...
|
| Pancreatic cancer |
-1.17 |
7.33e-1 |
75/76 (98.68%) |
MAP2K1;BAX;MAPK1;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
-1.17 |
7.50e-1 |
62/70 (88.57%) |
IKBKB;CXCR2;ATP6V0C;...
|
| African trypanosomiasis |
-1.20 |
7.26e-1 |
32/37 (86.49%) |
SELE;VCAM1;IL18;...
|
| Lysosome |
-1.20 |
7.47e-1 |
115/128 (89.84%) |
CLN5;MANBA;FUCA1;...
|
| B cell receptor signaling pathway |
-1.22 |
7.18e-1 |
71/81 (87.65%) |
NFKBIE;PTPN6;MAP2K1;...
|
| Valine, leucine and isoleucine degradation |
-1.22 |
7.50e-1 |
42/48 (87.5%) |
ALDH3A2;BCKDHA;ACAD8;...
|
| ErbB signaling pathway |
-1.24 |
7.00e-1 |
79/85 (92.94%) |
NCK1;JUN;RPS6KB2;...
|
| Ferroptosis |
-1.27 |
5.99e-1 |
36/41 (87.8%) |
SLC11A2;ATG7;ACSL1;...
|
| Autophagy |
-1.28 |
6.23e-1 |
113/169 (66.86%) |
SNAP29;BCL2L1;MTMR3;...
|
| Nitrogen metabolism |
-1.28 |
6.20e-1 |
16/17 (94.12%) |
CA12;CA2
|
| Phosphatidylinositol signaling system |
-1.29 |
6.46e-1 |
82/97 (84.54%) |
PIP5K1B;PLCB1;MTMR3;...
|
| Inositol phosphate metabolism |
-1.31 |
5.83e-1 |
66/73 (90.41%) |
INPP5J;PIP5K1B;PLCB1;...
|
| Rheumatoid arthritis |
-1.32 |
5.66e-1 |
78/93 (83.87%) |
TNFRSF11A;HLA-DMB;ATP6V0C;...
|
| Steroid hormone biosynthesis |
-1.33 |
5.95e-1 |
43/61 (70.49%) |
HSD17B8;CYP21A2;HSD3B2;...
|
| Estrogen signaling pathway |
-1.33 |
6.15e-1 |
119/137 (86.86%) |
ITPR1;JUN;MMP9;...
|
| Renal cell carcinoma |
-1.36 |
5.52e-1 |
68/69 (98.55%) |
PAK3;PAK5;PIK3CA;...
|
| Phototransduction |
-1.36 |
5.90e-1 |
21/29 (72.41%) |
CALML4;CALML3;CALML5
|
| Aldosterone-regulated sodium reabsorption |
-1.38 |
5.58e-1 |
34/37 (91.89%) |
NEDD4L;SGK1;INSR;...
|
| Colorectal cancer |
-1.38 |
6.17e-1 |
84/86 (97.67%) |
BAK1;GADD45B;BCL2L11;...
|
| Histidine metabolism |
-1.39 |
6.60e-1 |
16/22 (72.73%) |
ALDH3A1;AOC1;HAL;...
|
| Synaptic vesicle cycle |
-1.42 |
5.61e-1 |
63/78 (80.77%) |
RAB3A;STX3;ATP6V0C;...
|
| Ascorbate and aldarate metabolism |
-1.42 |
6.46e-1 |
15/30 (50%) |
UGT2B15;UGT2B17;UGT2A3;...
|
| SNARE interactions in vesicular transport |
-1.44 |
6.99e-1 |
19/33 (57.58%) |
STX8;SNAP29;STX11;...
|
| Sphingolipid metabolism |
-1.47 |
6.94e-1 |
32/49 (65.31%) |
CERS6;SMPD2;SGPP1;...
|
| Folate biosynthesis |
-1.79 |
7.33e-2 |
23/26 (88.46%) |
GGH;ALPL;PAH;...
|
| Collecting duct acid secretion |
-1.82 |
1.03e-1 |
22/27 (81.48%) |
ATP6V0A4;ATP6V1C1;ATP6V1B1;...
|
