Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMX8CVY)

Drug Name
Pivampicillin Drug Info
Synonyms
Pivaloylampicillin; Pivampicilina; Pivampicilline; Pivampicillinum; Pondocillin; Ampicillin Pivaloyl Ester; Ampicillin pivaloyloxymethyl ester; Pivaloyloxymethyl ampicillinate; Pivampicillin Monohydrochloride; MK 191; Pivampicilina [INN-Spanish]; Pivampicillin (INN); Pivampicillin [INN:BAN]; Pivampicilline [INN-French]; Pivampicillinum [INN-Latin]; Pondocillin (TN); [(2,2-dimethylpropanoyl)oxy]methyl 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylate; 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Therapeutic ClassAntibiotics
Cross-matching ID
PubChem CID
33478
ChEBI ID
CHEMBL8255
CAS Number
CAS 33817-20-8
TTD Drug ID
D04KAQ

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Oxidative phosphorylation 2.07 0.00e+0 93/133 (69.92%) NDUFB8;ATP6V1F;COX17;...
Proteasome 1.93 1.96e-2 44/46 (95.65%) PSMD2;PSMB3;PSMA4;...
Cardiac muscle contraction 1.92 1.57e-2 64/87 (73.56%) TPM2;TPM3;ATP1B3;...
RNA polymerase 1.79 1.96e-2 23/31 (74.19%) POLR2H;POLR1D;POLR2I;...
Huntington disease 1.74 3.76e-2 233/306 (76.14%) POLR2H;PSMD2;NDUFB8;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H