Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMY3T0L)

• Drug Name: DS-1211 Drug Info
• Synonyms: N-Acetyl-D-leucine; 19764-30-8; Ac-D-Leu-OH; D-leucine, N-acetyl-; N-Acetyl-R-leucine; (2R)-2-acetamido-4-methylpentanoic acid; Acetylleucine, D-; Acetylleucine, (R)-; (R)-2-acetamido-4-methylpentanoic acid; Leucine, N-acetyl-, D-; acetyl-d-leucine; 91WU82GA22; MFCD00066069; 2,N-Acetyl-D-leucine; D-acetylleucine; UNII-91WU82GA22; (R)-acetylleucine; N-acetyl-D-Leu; NCGC00094935-01; N-acetyl-(D)-leucine; SCHEMBL714003; CHEMBL174357; CHEBI:94479; DTXSID50361310; CHEBI:146296; WXNXCEHXYPACJF-SSDOTTSWSA-N; HY-Y1080; s4514; AKOS016842336; AKOS025117328; CCG-266380; CS-W020713; DS-1211; FD21901; NCGC00094935-02; AC-22376; A0713; AM20090137; A-1455; A20910; EN300-321381; Q-100200; BRD-K05831461-001-01-8; Z851793110
• Cross-matching ID:
  PubChem CID: 1241420
  TTD Drug ID: D29GPF

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Peroxisome	-1.83	4.76e-2	72/82 (87.8%)	PECR;ECI2;AGPS;...
Protein digestion and absorption	-1.95	3.30e-2	78/103 (75.73%)	CELA2B;COL4A5;SLC7A7;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Hide ▲