Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMYISTE)

• Drug Name: EPZ005687 Drug Info
• Synonyms: EPZ-005687; EPZ 005687
• Cross-matching ID:
  PubChem CID: 60160561
  ChEBI ID: CHEMBL3360855
  CAS Number: CAS 1396772-26-1
  TTD Drug ID: D02BBA

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Steroid biosynthesis	1.97	0.00e+0	19/20 (95%)	FDFT1;SQLE;MSMO1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	6.66uM	6H	Hide ▲

Lung

Lung adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A549	CVCL_0023	Homo sapiens	6.66uM	6H	Hide ▲

Pancreas

Pancreatic carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
YAPC	CVCL_1791	Homo sapiens	6.66uM	6H	Show ▼

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	6.66uM	6H	Show ▼

Skin

Melanoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A-375	CVCL_0132	Homo sapiens	6.66uM	6H	Show ▼