Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMYZFXN)

Drug Name
Lornoxicam Drug Info
Synonyms CTX; Chlortenoxicam; Lorcam; Safem; Telos; Xefo; Xefo Rapid; HN-10000; TS-110; Ro-13-9297
Cross-matching ID
PubChem CID
54690031
ChEBI ID
CHEMBL31783
CAS Number
CAS 70374-39-9
TTD Drug ID
D0UL2L
INTEDE Drug ID
DR0981

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
TNF signaling pathway 2.04 0.00e+0 103/112 (91.96%) CXCL2;CXCL1;CXCL3;...
Viral protein interaction with cytokine and cytokine re... 1.98 0.00e+0 84/100 (84%) CXCL2;CXCL1;CXCL3;...
IL-17 signaling pathway 1.95 4.70e-3 84/94 (89.36%) CXCL2;CXCL1;CXCL3;...
Chemokine signaling pathway 1.92 1.06e-2 163/192 (84.9%) CXCL2;CXCL1;CXCL3;...
Amoebiasis 1.82 3.67e-2 99/102 (97.06%) CXCL2;CXCL1;CXCL3;...
Legionellosis 1.81 4.00e-2 51/57 (89.47%) CXCL2;CXCL1;CXCL3;...
Rheumatoid arthritis 1.79 4.63e-2 78/93 (83.87%) CXCL2;CXCL1;CXCL3;...
Type II diabetes mellitus 1.77 4.41e-2 42/46 (91.3%) SOCS2;PIK3R1;TNF;...
ErbB signaling pathway 1.74 4.74e-2 79/85 (92.94%) NCK1;CRKL;PIK3R1;...
Human cytomegalovirus infection 1.73 4.82e-2 201/225 (89.33%) CXCR4;ROCK2;CRKL;...
Spliceosome 1.72 4.66e-2 101/150 (67.33%) LSM5;DDX42;PRPF18;...
Riboflavin metabolism -1.80 3.84e-2 7/8 (87.5%) ENPP1;BLVRB;ACP5
Nucleotide excision repair -1.83 3.84e-2 40/47 (85.11%) LIG1;CCNH;ERCC4;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Bone
Ewing sarcoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
SK-ES-1 CVCL_0627 Homo sapiens 1.11uM - 10uM 24H
Brain
Glioma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
GI-1 CVCL_1230 Homo sapiens 1.11uM - 10uM 24H
Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MDA-MB-468 CVCL_0419 Homo sapiens 1.11uM - 10uM 24H
Breast ductal carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
T-47D CVCL_0553 Homo sapiens 1.11uM - 10uM 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
SNU-407 CVCL_5004 Homo sapiens 1.11uM - 10uM 24H
Endometrium
Endometrial adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HEC-108 CVCL_2926 Homo sapiens 1.11uM - 10uM 24H
HEC-1-A CVCL_0293 Homo sapiens 1.11uM - 10uM 24H
HEC-251 CVCL_2928 Homo sapiens 1.11uM - 10uM 24H
HEC-265 CVCL_2929 Homo sapiens 1.11uM - 10uM 24H
Hematopoietic system
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
CJM CVCL_U797 Homo sapiens 1.11uM - 10uM 24H
Liver
Hepatocellular carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
JHH-5 CVCL_1320 Homo sapiens 1.11uM - 10uM 24H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
NCI-H1573 CVCL_1483 Homo sapiens 1.11uM - 10uM 24H
NCI-H838 CVCL_1594 Homo sapiens 1.11uM - 10uM 24H
Lung squamous cell carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
BEN CVCL_1081 Homo sapiens 1.11uM - 10uM 24H
HCC95 CVCL_1276 Homo sapiens 1.11uM - 10uM 24H
Muscle
Rhabdomyosarcoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-204 CVCL_0134 Homo sapiens 1.11uM - 10uM 24H
Ovary
Ovarian clear cell carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
OVTOKO CVCL_3114 Homo sapiens 1.11uM - 10uM 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
22Rv1 CVCL_1045 Homo sapiens 1.11uM - 10uM 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
IGR-37 CVCL_1303 Homo sapiens 1.11uM - 10uM 24H
Mel-HO CVCL_1402 Homo sapiens 1.11uM - 10uM 24H
SH-4 CVCL_1692 Homo sapiens 1.11uM - 10uM 24H
Urinary bladder
Bladder carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
BC-3C CVCL_1079 Homo sapiens 1.11uM - 10uM 24H
Bladder transitional cell carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
CAL-29 CVCL_1109 Homo sapiens 1.11uM - 10uM 24H