Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMZGCEQ)

Drug Name
1,2,3,4-tetrahydroisoquinoline Drug Info
Synonyms
1,2,3,4-Tetrahydroisoquinoline; 91-21-4; Tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-isoquinoline; ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-; 1,2,3,4-Tetrahydro isoquinoline; EINECS 202-050-0; NSC 15312; 1,2,3,4-Tetrahydro-2-isoquinoline; 1,2,3,4-Tetrahydro-2-azanaphthalene; BRN 0116156; UNII-56W89FBX3E; CHEMBL14346; AI3-15931; 56W89FBX3E; UWYZHKAOTLEWKK-UHFFFAOYSA-N; MFCD00006896; 1,2,3,4-Tetrahydroisoquinoline, 95%; 3,4-dihydro-1H-isoquinoline; tetrahydroisoquinolin; tetrahyroisoquinoline; tetrahydro-isoquinoline; PubChem7253; AC1L1NVS
Cross-matching ID
PubChem CID
7046
ChEBI ID
CHEMBL14346
CAS Number
CAS 91-21-4
TTD Drug ID
D03EPY

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Staphylococcus aureus infection 2.19 0.00e+0 72/95 (75.79%) C3;C1S;CFI;...
IL-17 signaling pathway 2.16 0.00e+0 84/94 (89.36%) S100A9;S100A8;CXCL1;...
Systemic lupus erythematosus 2.01 3.38e-3 45/135 (33.33%) C3;C1S;C7;...
Pertussis 1.85 2.03e-2 64/76 (84.21%) C3;C1S;C1R;...
Complement and coagulation cascades 1.83 2.03e-2 76/85 (89.41%) C3;C1S;C7;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast
Nasopharyngeal carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
FIBRNPC CVCL_UK07 Homo sapiens 10uM 6H, 24H