| Steroid biosynthesis |
1.78 |
1.91e-1 |
19/20 (95%) |
EBP;CYP27B1;TM7SF2;...
|
| Tyrosine metabolism |
1.74 |
1.31e-1 |
30/36 (83.33%) |
ADH1B;ALDH3A1;AOC3;...
|
| ECM-receptor interaction |
1.72 |
1.19e-1 |
80/88 (90.91%) |
VWF;COL6A3;AGRN;...
|
| Protein digestion and absorption |
1.62 |
1.97e-1 |
78/103 (75.73%) |
COL6A3;COL15A1;KCNN4;...
|
| Pancreatic secretion |
1.62 |
1.58e-1 |
87/102 (85.29%) |
PLCB3;SLC12A2;FXYD2;...
|
| Synthesis and degradation of ketone bodies |
1.59 |
1.74e-1 |
9/10 (90%) |
HMGCS1;ACAT2;BDH2;...
|
| Ether lipid metabolism |
1.58 |
1.78e-1 |
32/49 (65.31%) |
LPCAT1;PAFAH1B3;PLA2G1B;...
|
| Adherens junction |
1.57 |
1.74e-1 |
63/71 (88.73%) |
SRC;TGFBR2;SORBS1;...
|
| Bacterial invasion of epithelial cells |
1.55 |
1.70e-1 |
59/77 (76.62%) |
SRC;CAV1;CAV2;...
|
| Proximal tubule bicarbonate reclamation |
1.55 |
1.55e-1 |
21/23 (91.3%) |
FXYD2;ATP1A2;PCK2;...
|
| Aldosterone-regulated sodium reabsorption |
1.55 |
1.53e-1 |
34/37 (91.89%) |
IRS1;NR3C2;SCNN1A;...
|
| Metabolism of xenobiotics by cytochrome P450 |
1.52 |
1.78e-1 |
49/77 (63.64%) |
ADH1B;ALDH3A1;HSD11B1;...
|
| Sulfur relay system |
1.52 |
1.71e-1 |
5/8 (62.5%) |
TST;MOCS2;MPST
|
| Phenylalanine metabolism |
1.51 |
1.68e-1 |
14/17 (82.35%) |
ALDH3A1;AOC3;MAOA;...
|
| PPAR signaling pathway |
1.51 |
1.68e-1 |
66/74 (89.19%) |
SCD;FABP4;SORBS1;...
|
| Sulfur metabolism |
1.48 |
1.89e-1 |
9/10 (90%) |
TST;ETHE1;PAPSS2;...
|
| Base excision repair |
1.46 |
2.02e-1 |
29/33 (87.88%) |
PARP2;HMGB1;PCNA;...
|
| Mineral absorption |
1.45 |
2.23e-1 |
48/60 (80%) |
MT1H;MT1E;MT1HL1;...
|
| Glutathione metabolism |
1.44 |
2.15e-1 |
43/57 (75.44%) |
GPX4;GPX1;GSTM2;...
|
| Glycerolipid metabolism |
1.44 |
2.12e-1 |
44/61 (72.13%) |
DGKD;AKR1B10;LPL;...
|
| Focal adhesion |
1.41 |
2.40e-1 |
180/201 (89.55%) |
SRC;VWF;CAV1;...
|
| Salivary secretion |
1.40 |
2.47e-1 |
76/93 (81.72%) |
LYZ;KCNN4;PLCB3;...
|
| Basal cell carcinoma |
1.40 |
2.40e-1 |
41/63 (65.08%) |
BAX;TP53;DDB2;...
|
| alpha-Linolenic acid metabolism |
1.38 |
2.63e-1 |
17/25 (68%) |
PLA2G1B;PLA2G6;PLAAT3;...
|
| Tight junction |
1.38 |
2.62e-1 |
130/169 (76.92%) |
SRC;MYH11;SYNPO;...
|
| AMPK signaling pathway |
1.37 |
2.67e-1 |
106/120 (88.33%) |
SCD;CPT1A;IRS1;...
|
| Glycosphingolipid biosynthesis |
1.32 |
3.60e-1 |
37/57 (64.91%) |
ST3GAL5;ST3GAL1;B3GNT3;...
|
| Drug metabolism |
1.30 |
3.87e-1 |
78/151 (51.66%) |
ADH1B;ALDH3A1;FMO2;...
|
| Fatty acid degradation |
1.29 |
3.94e-1 |
40/43 (93.02%) |
ADH1B;CPT1A;ALDH9A1;...
|
| Fluid shear stress and atherosclerosis |
1.29 |
3.81e-1 |
123/139 (88.49%) |
SRC;CAV1;CAV2;...
|
| Malaria |
-1.41 |
2.37e-1 |
44/50 (88%) |
MET;SDC2;TLR2;...
|
| Nicotine addiction |
-1.41 |
2.24e-1 |
32/40 (80%) |
GABRA2;GABRA1;GABRP;...
|
| Kaposi sarcoma-associated herpesvirus infection |
-1.42 |
2.27e-1 |
172/193 (89.12%) |
CASP3;MAPK1;GSK3B;...
|
| Alcoholism |
-1.43 |
2.22e-1 |
86/186 (46.24%) |
HDAC2;BRAF;SLC18A1;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
-1.43 |
2.24e-1 |
62/70 (88.57%) |
CASP3;NFKBIA;ATP6V0A1;...
|
| Cytokine-cytokine receptor interaction |
-1.43 |
2.27e-1 |
246/295 (83.39%) |
CCL27;IL11;BMPR2;...
|
| Chemokine signaling pathway |
-1.44 |
2.31e-1 |
163/192 (84.9%) |
PIK3CA;CX3CR1;CXCR6;...
|
| Arginine biosynthesis |
-1.44 |
2.37e-1 |
17/22 (77.27%) |
GLUL;ARG2;GLUD2;...
|
| Leukocyte transendothelial migration |
-1.45 |
2.40e-1 |
90/114 (78.95%) |
ITGB2;PIK3CA;CXCL12;...
|
| Alanine, aspartate and glutamate metabolism |
-1.46 |
2.17e-1 |
27/37 (72.97%) |
ASL;GLS;ALDH4A1;...
|
| Neomycin, kanamycin and gentamicin biosynthesis |
-1.47 |
2.21e-1 |
5/5 (100%) |
HK1;HK2;HK3
|
| NOD-like receptor signaling pathway |
-1.47 |
2.33e-1 |
145/181 (80.11%) |
MAPK9;CASP4;RHOA;...
|
| Selenocompound metabolism |
-1.49 |
2.10e-1 |
11/17 (64.71%) |
CTH;TXNRD1;PAPSS1;...
|
| HIF-1 signaling pathway |
-1.49 |
2.15e-1 |
105/109 (96.33%) |
PIK3CA;HK1;MAPK1;...
|
| Lipid and atherosclerosis |
-1.50 |
2.16e-1 |
190/215 (88.37%) |
CASP3;MAPK1;GSK3B;...
|
| Protein export |
-1.53 |
1.78e-1 |
17/23 (73.91%) |
SEC61A1;SRP9;SEC63;...
|
| Neutrophil extracellular trap formation |
-1.56 |
1.42e-1 |
101/189 (53.44%) |
C5;HDAC9;HDAC1;...
|
| Toll-like receptor signaling pathway |
-1.57 |
1.47e-1 |
94/104 (90.38%) |
MAPK1;NFKBIA;MAP2K6;...
|
| Rheumatoid arthritis |
-1.61 |
1.02e-1 |
78/93 (83.87%) |
IL11;CSF1;TNFSF13;...
|
| TNF signaling pathway |
-1.61 |
1.04e-1 |
103/112 (91.96%) |
CASP3;MAPK1;NFKBIA;...
|
| NF-kappa B signaling pathway |
-1.62 |
1.11e-1 |
90/104 (86.54%) |
LYN;TICAM1;LY96;...
|
| Amoebiasis |
-1.62 |
1.18e-1 |
99/102 (97.06%) |
CXCL2;PRKACB;ITGB2;...
|
| Staphylococcus aureus infection |
-1.63 |
1.22e-1 |
72/95 (75.79%) |
C3AR1;C1R;KRT33B;...
|
| Protein processing in endoplasmic reticulum |
-1.64 |
1.34e-1 |
127/171 (74.27%) |
SSR1;HSPA1A;HSP90AA1;...
|
| Natural killer cell mediated cytotoxicity |
-1.67 |
1.13e-1 |
99/131 (75.57%) |
KIR2DL1;BRAF;KRAS;...
|
| Fc epsilon RI signaling pathway |
-1.67 |
1.31e-1 |
57/68 (83.82%) |
SOS1;PIK3CB;IL13;...
|
| T cell receptor signaling pathway |
-1.72 |
8.51e-2 |
93/104 (89.42%) |
PIK3CA;CD28;MAPK1;...
|
| IL-17 signaling pathway |
-1.75 |
6.48e-2 |
84/94 (89.36%) |
CASP3;MAPK1;GSK3B;...
|
| Pertussis |
-1.80 |
6.08e-2 |
64/76 (84.21%) |
C1R;ITGB2;CASP3;...
|
| Legionellosis |
-1.83 |
7.29e-2 |
51/57 (89.47%) |
TLR2;PYCARD;HSPA8;...
|
