Details of the Drug Reposition

General Information of This Drug (ID: DM0FB1J)

Drug Name
Sertraline   DM0FB1J
Synonyms
Lustral; SRE; Sertralina; Sertralinum; Sertralina [Spanish]; Sertraline [Zoloft]; Sertralinum [Latin]; CP 51974; Cp 51974; Apo-Sertraline; Lustral (TN); Sertraline (INN); Sertraline (Zoloft); Sertraline [INN:BAN]; Zoloft (TN); (+)-Sertraline; (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine; (1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine; (1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine
Therapeutic Class
Antidepressants
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
6 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Depression DIS3XJ69 6A70-6A7Z Approved [1]
Panic disorder DISD3VNY 6B01 Approved [2]
Obsessive compulsive disorder DIS1ZMM2 6B20 Approved [2]
Post-traumatic stress disorder DISHL1EY 6B40 Approved [2]
Epilepsy DISBB28L 8A60-8A68 Approved [2]
Coronary heart disease DIS5OIP1 BA80.Z Approved [2]
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⏷ Show the Full List of 6 Indications(s)
1 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Social phobia DISQGN78 6B04 Discontinued in Phase 2 [3]
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4798).
2 Sertraline FDA Label
3 A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer