Details of the Drug Reposition

General Information of This Drug (ID: DMCV109)

• Drug Name: Etanercept (DMCV109)
• Synonyms: Etanercept (sciatica); Etanercept (sciatica), BioAssets Development; Etanercept (sciatica), Cephalon
• Drug Type: Monoclonal antibody

Information on Drug Reposition of This Drug

2 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Arthritis	DIST1YEL	FA20	Approved	[1]
Psoriatic arthritis	DISLWTG2	FA21	Approved	[2]

1 Phase 3 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Sciatica	DISFGDES	ME84.3	Phase 3	[3]

1 Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Pemphigus vulgaris	DISENR62	EB40	Phase 2	[4]

1 Discontinued in Phase 3 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Juvenile idiopathic arthritis	DISQZGBV	FA24	Discontinued in Phase 3	[5]

1 Discontinued in Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Ankylosing spondylitis	DISRC6IR	FA92.0	Discontinued in Phase 2	[6]

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
• [2] Etanercept and Methotrexate as Monotherapy or in Combination for Psoriatic Arthritis: Primary Results From a Randomized, Controlled Phase III Trial. Arthritis Rheumatol. 2019 Jul;71(7):1112-1124.
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6789).
• [4] ClinicalTrials.gov (NCT00135720) Study of Etanercept (Enbrel) in the Treatment of Pemphigus Vulgaris
• [5] A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy
• [6] Effect of Local Anesthesia in Patients With Marginal Periodontitis Undergoing Scaling and Root Planning