Details of the Drug Reposition

General Information of This Drug (ID: DMFNH7L)

• Drug Name: Pentobarbital (DMFNH7L)
• Synonyms: Aethaminalum; Dorsital; Etaminal; Ethaminal; Mebubarbital; Mebumal; Nebralin; Nembutal; Neodorm; Pentabarbital; Pentabarbitone; Pentobarbitale; Pentobarbitalum; Pentobarbitone; Pentobarbiturate; Rivadorm; Pentobarbital calcium; Pentobarbital suppository dosage form; Pentobarbitale [DCIT]; Pentobarbituric acid; Ethyl-propylmethylcarbinylbarbituric acid; Nembutal (TN); Nembutal (VAN); Neodorm (VAN); Neodorm (new); Pentobarbital (VAN); Pentobarbital [USP:INN]; Pentobarbital, Monosodium Salt; Pentobarbitalum [INN-Latin]; Pentobarbitone (VAN); Pentobarbital (USP/INN); (+-)-5-Ethyl-5-(1-methylbutyl)barbituric acid; 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-(1-methylbutyl)barbituric acid; 5-Ethyl-5-(1-methylbutyl)malonylurea; 5-Ethyl-5-(sec-pentyl)barbituric acid; 5-ethyl-2-hydroxy-5-(1-methylbutyl)pyrimidine-4,6(1H,5H)-dione; 5-ethyl-5-(pentan-2-yl)pyrimidine-2,4,6(1H,3H,5H)-trione;5-ethyl-5-pentan-2-yl-1,3-diazinane-2,4,6-trione
• Therapeutic Class: Hypnotics and Sedatives
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

3 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Insomnia	DIS0AFR7	7A00-7A0Z	Approved	[1]
Epilepsy	DISBB28L	8A60-8A68	Approved	[2]
Brain ischaemia	DIS9Q4RT	8B1Z	Approved	[2]

1 Discontinued in Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Status epilepticus seizure	DISY3BIC	8A66.1Y	Discontinued in Phase 2	[3]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5480).
• [2] Pentobarbital FDA Label
• [3] Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease