Details of the Drug Reposition

General Information of This Drug (ID: DMQKZDT)

Drug Name
Talnetant   DMQKZDT
Synonyms
Talnetant [INN]; SB 223412; SB-223412; N-((S)-alpha-Ethylbenzyl)-3-hydroxy-2-phenylcinchoninamide;N-(alpha-Ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide; 3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
1 Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Schizophrenia DISSRV2N 6A20 Phase 2 [1]
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2 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Schizoaffective disorder DISLBW6B 6A21 Discontinued in Phase 2 [2]
Irritable bowel syndrome DIS27206 DD91.0 Discontinued in Phase 2 [2]
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References

1 ClinicalTrials.gov (NCT00300963) Effect Of Talnetant Versus Risperidone Versus Placebo On Psychotic Symptoms In Schizophrenic Patients in GlaxoSmithKline.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2132).