Details of the Drug Reposition | DrugMAP

General Information of This Drug (ID: DMQMV1B)

Drug Name	Adalimumab DMQMV1B
Synonyms	Humira; Adalimumab (genetical recombination); Humira (TN); Adalimumab (USAN/INN); Adalimumab (genetical recombination) (JAN)
Therapeutic Class	Antirheumatic Agents
Drug Type	Antibody

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)

8 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Coronavirus Disease 2019 (COVID-19)	DISM7GNX	1D6Y	Approved	[1]
Sarcoidosis	DISE5B8Z	4B20.5	Approved	[2]
Mucositis	DIS3FXDI	CA00	Approved	[3]
Crohn disease	DIS2C5Q8	DD70	Approved	[4]
Ulcerative colitis	DIS8K27O	DD71	Approved	[5]
Pyoderma gangrenosum	DIS8QVTT	EB21	Approved	[6]
Hidradenitis suppurativa	DIS3ZNAK	ED92.0	Approved	[7]
Psoriatic arthritis	DISLWTG2	FA21	Approved	[8]
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⏷ Show the Full List of 8 Indications(s)

3 Discontinued in Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Rheumatoid arthritis	DISTSB4J	FA20	Discontinued in Phase 2	[9]
Juvenile idiopathic arthritis	DISQZGBV	FA24	Discontinued in Phase 2	[10]
Ankylosing spondylitis	DISRC6IR	FA92.0	Discontinued in Phase 2	[11]
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References

1	Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed. Lancet. 2020 May 2;395(10234):1407-1409.
2	Sarcoidosis-associated acro-osteolysis. BMJ Case Rep. 2021 Mar 2;14(3):e240828.
3	Identification of potential molecular mechanisms and candidate drugs for radiotherapy- and chemotherapy-induced mucositis. Support Care Cancer. 2023 Mar 20;31(4):223.
4	Management of inflammatory bowel disease. Med J Aust. 2018 Sep 1;209(7):318-323.
5	First- and Second-Line Pharmacotherapies for Patients With Moderate to Severely Active Ulcerative Colitis: An Updated Network Meta-Analysis. Clin Gastroenterol Hepatol. 2020 Sep;18(10):2179-2191.e6.
6	An update on adalimumab for pyoderma gangrenosum. Drugs Today (Barc). 2021 Sep;57(9):535-542.
7	Hidradenitis Suppurativa: Advances in Diagnosis and Treatment. JAMA. 2017 Nov 28;318(20):2019-2032.
8	Trial of Upadacitinib and Adalimumab for Psoriatic Arthritis. N Engl J Med. 2021 Apr 1;384(13):1227-1239.
9	Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment Strategy
10	A Phase 1-2, XIAP Antisense AEG35156 With Gemcitabine in Patients With Advanced Pancreatic Cancer
11	Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor