Details of the Drug Reposition

General Information of This Drug (ID: DMZ5RGV)

Drug Name
Naproxen   DMZ5RGV
Synonyms
NAPROXEN; 22204-53-1; (S)-Naproxen; Naproxene; Naprosyn; (+)-Naproxen; Equiproxen; Laraflex; Naproxenum; Naproxeno; d-Naproxen; (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid; (S)-(+)-Naproxen; Calosen; Nycopren; Naprosyne; Bonyl; Reuxen; Naixan; Axer; (+)-(S)-Naproxen; Ec-Naprosyn; (S)-2-(6-methoxynaphthalen-2-yl)propanoic acid; Flexipen; Clinosyn; Artrixen; Anexopen; Acusprain; Novonaprox; Arthrisil; Leniartil; Danaprox; Bipronyl; Artroxen; Napren; Naposin; Napflam; Genoxen; Daprox; Atiflan; Artagen; Apronax; Naprius; Nalyxan; Lefaine; Congex
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
7 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Migraine disorder DISFCQTG N.A. Approved [1]
Bursitis DISCF7Y9 N.A. Approved [1]
Headache DISK4TGU 8A80-8A84 Approved [1]
Osteoarthritis DIS05URM FA00-FA05 Approved [2]
Gout DISHC0U7 FA25 Approved [1]
Dysmenorrhea DISMYBW9 GA34.3 Approved [1]
Fever DISJGEAQ MG26 Approved [1]
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⏷ Show the Full List of 7 Indications(s)
1 Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Pain DIS4RWOW MG30-MG3Z Phase 2 [3]
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1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Fibromyalgia DISZJDS2 MG30.01 Withdrawn [4]
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2 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Tendinitis DISS7ANY N.A. Discontinued in Phase 3 [5]
Ankylosing spondylitis DISRC6IR FA92.0 Discontinued in Phase 3 [6]
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1 Discontinued in Phase 1 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Rheumatoid arthritis DISTSB4J FA20 Discontinued in Phase 1 [7]
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1 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Endometriosis DISX1AG8 GA10 Investigative [8]
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References

1 Naproxen FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5230).
4 Opioids for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease
5 Study of Inhaled Nitric Oxide (iNO) and Respiratory Outcomes in Late Preterm Infants
6 Calfactant for Direct Acute Respiratory Distress Syndrome
7 Sirolimus for Eosinophil-Associated Gastrointestinal Disorders
8 New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202.