Details of the Drug Reposition

General Information of This Drug (ID: DMZOLBI)

• Drug Name: Carbamazepine (DMZOLBI)
• Synonyms: Carbamazepine (iv, epilepsy); Carbamazepine (iv, epilepsy), Lundbeck; Carbamazepine (iv, epilepsy), Ovation Pharmaceuticals
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

5 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Glossopharyngeal neuralgia	DISBUXSM	N.A.	Approved	[1]
Focal epilepsy	DIS4LY5L	N.A.	Approved	[1]
Epilepsy with generalized tonic-clonic seizures	DISMG0FL	N.A.	Approved	[1]
Epilepsy	DISBB28L	8A60-8A68	Approved	[2]
Trigeminal neuralgia	DIS31ZY6	8B82.0	Approved	[1]

1 NDA filed Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Type-1 diabetes	DIS7HLUB	5A10	NDA filed	[3]

1 Phase 3 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Gastric adenocarcinoma	DISWWLTC	2B72	Phase 3	[4]

1 Discontinued in Phase 2 Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
LennoxGastaut syndrome	DISOTGO5	8A62.1	Discontinued in Phase 2	[5]

References

• [1] Carbamazepine FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5339).
• [3] Clinical pipeline report, company report or official report of Lundbeck.
• [4] ClinicalTrials.gov (NCT01128959) Study to Assess the Safety and Tolerability of Intravenous Carbamazepine in Adults With Epilepsy. U.S. National Institutes of Health.
• [5] A Study of Sunitinib in Combination With Bevacizumab, Carboplatin, and Paclitaxel in Patients With Advanced Non-Small Cell Lung Cancer (SABRE-L)