Details of the Drug

General Information of Drug (ID: DM00P8M)

Drug Name

BST-236

Synonyms

Aspacytarabine; UNII-JL7V54Z2BR; JL7V54Z2BR; 2098942-53-9; N4-(1-beta-D-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin-4-yl)-; Astarabine; Aspacytarabine [INN]; CHEMBL4297599; L-Asparagine, N-(1-beta-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-; N4-(1-N2-D-Arabinofuranosyl-2-oxo-1,2-dihydropyrimidin-4-yl)- L-asparagine

Indication

Disease Entry	ICD 11	Status	REF
Acute myeloid leukaemia	2A60	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C13H18N4O8
Canonical SMILES: C1=CN(C(=O)N=C1NC(=O)CC(C(=O)O)N)C2C(C(C(O2)CO)O)O
InChI: 1S/C13H18N4O8/c14-5(12(22)23)3-8(19)15-7-1-2-17(13(24)16-7)11-10(21)9(20)6(4-18)25-11/h1-2,5-6,9-11,18,20-21H,3-4,14H2,(H,22,23)(H,15,16,19,24)/t5-,6+,9+,10-,11+/m0/s1
InChIKey: PVPJTBAEAQVTPN-HRAQMCAYSA-N

Cross-matching ID

PubChem CID: 135390942
CAS Number: 2098942-53-9
UNII: JL7V54Z2BR
DrugBank ID: DB17226
TTD ID: DGN26L

References

1	ClinicalTrials.gov (NCT04827719) BST-236 as a Single Agent in Adults With Relapsed or Refractory AML or HR-MDS. U.S. National Institutes of Health.