Details of the Drug

General Information of Drug (ID: DM065ZH)

Drug Name
CCT-018159
Synonyms
CCT 018159; CCT018159; (6Z)-6-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one; 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethylbenzene-1,3-diol
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Preclinical [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 352.4
Logarithm of the Partition Coefficient (xlogp) 3.7
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C20H20N2O4
IUPAC Name
4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethylbenzene-1,3-diol
Canonical SMILES
CCC1=CC(=C(C=C1O)O)C2=NNC(=C2C3=CC4=C(C=C3)OCCO4)C
InChI
InChI=1S/C20H20N2O4/c1-3-12-8-14(16(24)10-15(12)23)20-19(11(2)21-22-20)13-4-5-17-18(9-13)26-7-6-25-17/h4-5,8-10,23-24H,3,6-7H2,1-2H3,(H,21,22)
InChIKey
OWPMENVYXDJDOW-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
984170
ChEBI ID
CHEBI:41656
CAS Number
171009-07-7
UNII
55H1ZOI1NL
DrugBank ID
DB07594
TTD ID
D00OCB

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heat shock protein 90 alpha (HSP90A) TT78R5H HS90A_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Heat shock protein 90 alpha (HSP90A) DTT HSP90AA1 3.96E-01 0.18 0.48
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 2.8587 4.4943 2.3159 9.7879
HuO9 GDSC1 1.9857 4.8326 1.2882 21.5478
HOS GDSC1 2.4528 3.4605 2.3323 11.6662
ES8 GDSC1 2.6667 4.2647 2.2342 11.2887
ES7 GDSC1 2.7059 5.2769 1.7932 14.4634
NY GDSC1 2.7516 4.4373 2.2388 10.8595
ES4 GDSC1 2.8663 3.9824 2.5633 7.8672
SJSA-1 GDSC1 2.9829 4.5554 2.404 8.5681
CAL-72 GDSC1 3.0728 4.5583 2.4856 7.5573
EW-11 GDSC1 3.099 9.4634 0.0635 24.1275
A-673 GDSC1 3.1187 4.7587 2.4278 7.8234
MG-63 GDSC1 3.1484 5.2752 2.1972 9.5161
H-EMC-SS GDSC1 3.164 5.0631 2.3164 8.5202
NOS-1 [Human HNSCC] GDSC1 3.1864 5.6499 2.0431 10.5746
EW-16 GDSC1 3.3085 5.103 2.4202 7.1599
ES1 GDSC1 3.3455 4.5862 2.7093 4.7467
EW-12 GDSC2 3.346 5.3752 2.3153 6.3036
TC-71 GDSC1 3.3515 4.9834 2.5158 6.2514
ES6 GDSC1 3.4147 6.2781 1.9204 10.6895
MHH-ES-1 GDSC1; GDSC2 3.434 5.4531 2.3483 5.8461
CAL-78 GDSC1 3.4909 4.6597 2.7881 3.6361
CHSA0108 GDSC1; GDSC2 3.5256 6.3028 1.9976 7.8073
SK-ES-1 GDSC1 3.6277 7.0237 1.7193 11.4856
SaOS-2 GDSC1 3.7519 5.6637 2.4871 5.1799
U2OS GDSC1; GDSC2 3.8084 6.8442 1.9479 7.3764
HuO-3N1 GDSC1 3.9525 7.6134 1.6763 10.749
ES5 GDSC1; GDSC2 3.9563 5.9849 2.4748 3.7753
EW-22 GDSC1 4.1322 5.8227 2.6649 2.8779
EW-18 GDSC1 4.3039 6.3765 2.5147 3.5648
G-292 clone A141B1 GDSC1 4.3411 6.9491 2.2711 5.2341
EW-7 GDSC1 4.6224 6.497 2.6424 2.1011
U-CH2 GDSC2 4.6849 7.5491 2.2073 3.938
EW-24 GDSC1 4.8616 6.2523 2.856 0.6659
EW-1 GDSC1 4.9126 7.234 2.4784 2.6451
CHSA8926 GDSC1 5.1953 7.2493 2.613 1.4774
CADO-ES1 GDSC1 5.2233 7.0298 2.7123 0.9701
CHSA0011 GDSC1; GDSC2 5.2831 7.9589 2.3618 2.2256
EW-13 GDSC1 5.7086 7.9258 2.5762 1.132
EW-3 GDSC1 5.8595 8.7922 2.3006 2.3168
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 164 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 4.0406 5.6 2.7115 2.2071
SUP-HD1 GDSC1 -0.5158 7.5367 -2.4645 48.9912
MV4-11 GDSC1 1.059 2.8263 0.9678 28.8645
HAL-01 GDSC1 1.1413 3.1948 0.9756 28.3163
MOLM-16 GDSC1; GDSC2 1.4362 3.0654 1.328 19.4862
Kasumi-1 GDSC1; GDSC2 1.5018 3.2515 1.3544 19.0386
CRO-AP2 GDSC1; GDSC2 1.7007 3.8134 1.3976 17.9078
MOLT-16 GDSC1 1.7723 4.0228 1.3984 21.8958
CCRF-CEM GDSC1 1.8527 3.5551 1.6493 19.7175
Mono-Mac-6 GDSC1 1.8766 4.2044 1.4392 21.0532
OCI-AML-2 GDSC1 1.9464 2.6077 1.9402 17.2334
CTV-1 GDSC1 1.9758 2.8942 1.9437 17.031
TUR GDSC1 2.0574 3.7649 1.7998 17.5474
OCI-Ly7 GDSC1; GDSC2 2.0581 3.0378 2.0085 12.9386
RPMI-8866 GDSC1 2.0704 3.6654 1.849 17.1322
MOLM-13 GDSC1 2.0771 3.8856 1.7765 17.6066
NCI-H929 GDSC1 2.1149 3.3552 1.9954 15.8743
BC-3 GDSC2 2.2033 4.0697 1.8388 13.2486
DG-75 GDSC1 2.2694 4.2999 1.812 16.3591
JVM-3 GDSC1 2.319 4.8194 1.6322 17.4364
SUP-M2 GDSC1 2.3241 3.2933 2.2406 13.0191
BV-173 GDSC1 2.3249 4.4324 1.8118 16.0851
WSU-NHL GDSC1 2.3562 3.7216 2.1371 13.5614
SU-DHL-5 GDSC1 2.3712 3.7242 2.1522 13.3739
DND-41 GDSC1 2.4165 4.02 2.0834 13.6348
NKM-1 GDSC1 2.429 4.6476 1.821 15.514
BL-41 GDSC1 2.435 3.8953 2.1538 13.0284
EoL-1 GDSC1 2.4398 3.6391 2.2572 12.2626
ATN-1 GDSC1 2.4457 3.7984 2.2035 12.6142
U-698-M GDSC1 2.4528 4.0502 2.1088 13.2657
GR-ST GDSC1 2.4705 4.1726 2.0749 13.4262
KE-37 GDSC1 2.5024 4.0755 2.1497 12.7164
MOLT-4 GDSC1 2.5065 3.7599 2.2832 11.7242
NB4 GDSC1; GDSC2 2.5691 4.4353 2.0585 10.4963
SR GDSC1 2.6022 3.8952 2.3298 10.8945
L-540 GDSC1 2.6391 4.067 2.2945 10.9716
Karpas-231 GDSC1 2.6494 3.9992 2.3347 10.6227
H9 GDSC1 2.662 3.457 2.5607 8.9264
Karpas-45 GDSC1 2.6967 4.3701 2.2159 11.2867
DEL GDSC1 2.7133 4.1152 2.3489 10.2064
K-562 GDSC1 2.7295 4.0662 2.3873 9.8411
697 GDSC1 2.7454 4.195 2.345 10.0825
SU-DHL-1 GDSC2 2.7672 3.8586 2.5171 6.9782
RPMI-8226 GDSC1 2.8268 4.0231 2.5051 8.4927
CML-T1 GDSC1 2.8375 4.3306 2.3732 9.4434
NK-92MI GDSC2 2.8586 4.0914 2.5057 6.694
SU-DHL-10 GDSC1 2.8636 4.0186 2.5441 8.0244
RS4;11 GDSC1 2.9106 4.5767 2.3257 9.4852
GA-10 GDSC1 2.9483 4.8902 2.2082 10.2354
EM-2 GDSC1 2.9503 4.3231 2.4858 8.0764
NOMO-1 GDSC1 2.9567 4.6845 2.3166 9.358
L-1236 GDSC1 2.9596 4.1396 2.5824 7.292
CTB-1 GDSC1; GDSC2 2.9772 4.4627 2.4438 6.6501
LAMA-84 GDSC1 3.0009 4.7778 2.3117 9.2105
MHH-PREB-1 GDSC1 3.0089 4.7078 2.3535 8.852
HC-1 GDSC1 3.0471 5.5294 1.9816 11.5951
Daudi GDSC1 3.048 4.414 2.5336 7.2861
BONNA-12 GDSC2 3.0552 6.1957 1.6572 11.3259
Karpas-1106P GDSC1 3.0767 4.5998 2.4687 7.6733
KMOE-2 GDSC1 3.0793 4.2669 2.6346 6.3688
RL GDSC1; GDSC2 3.0824 4.0501 2.743 4.4265
SUP-B8 GDSC1; GDSC2 3.1061 4.4464 2.571 5.4212
JURL-MK1 GDSC1 3.1372 5.0834 2.2829 8.8871
AMO1 GDSC1 3.1492 4.9646 2.3526 8.2936
SKM-1 GDSC1; GDSC2 3.1611 4.5985 2.5452 5.4065
MLMA GDSC1 3.1705 4.8783 2.4142 7.7269
TALL-1 [Human adult T-ALL] GDSC2 3.1722 5.1477 2.2814 7.0366
SU-DHL-6 GDSC1 3.1797 4.8394 2.4417 7.4749
OPM-2 GDSC1 3.271 4.3423 2.7687 4.5508
GDM-1 GDSC1 3.2726 4.8925 2.4952 6.7007
Karpas-299 GDSC1 3.2799 5.2057 2.3448 7.8584
SU-DHL-16 GDSC1; GDSC2 3.2913 4.7346 2.59 4.7242
Loucy GDSC1 3.2987 4.5278 2.6995 4.9934
CMK GDSC1 3.3088 4.0429 2.9505 2.9775
OCI-Ly19 GDSC1; GDSC2 3.3129 5.2151 2.3678 6.0672
A3/Kawakami GDSC1 3.3259 4.3568 2.8078 4.0402
PL-21 GDSC1; GDSC2 3.3429 6.7729 1.6139 10.7272
JVM-2 GDSC1 3.3494 5.106 2.4527 6.7563
TK [Human B-cell lymphoma] GDSC1 3.3584 4.6577 2.6842 4.8992
Ramos.2G6.4C10 GDSC1 3.3666 4.6788 2.6804 4.9001
KCL-22 GDSC1 3.3679 4.922 2.5598 5.8461
HEL GDSC1; GDSC2 3.3749 4.9122 2.5705 4.6059
SIG-M5 GDSC2 3.3822 4.7148 2.6751 3.9236
Jiyoye GDSC1 3.4089 5.6243 2.2425 8.1994
Namalwa GDSC1 3.4153 5.0222 2.5483 5.7718
KMS-11 GDSC1; GDSC2 3.4174 5.0415 2.5404 4.6777
RPMI-8402 GDSC1 3.4302 5.1968 2.4732 6.3115
EJM GDSC1 3.4353 5.0388 2.5561 5.6413
BC-1 GDSC1 3.4578 6.4876 1.8509 11.0719
JeKo-1 GDSC1; GDSC2 3.4769 5.2391 2.4893 4.838
JJN-3 GDSC1 3.5096 5.54 2.3651 6.8916
BE-13 GDSC1 3.5205 5.159 2.5632 5.3025
L-363 GDSC1 3.5422 5.8519 2.2355 7.7978
MEG-01 GDSC1 3.5457 5.0427 2.6401 4.6191
MHH-CALL-2 GDSC1 3.548 5.7989 2.2664 7.5367
JSC-1 GDSC1 3.5493 6.4781 1.9291 10.1537
MY-M12 GDSC1; GDSC2 3.5559 5.173 2.5834 4.0386
MOLP-8 GDSC1 3.5662 5.5698 2.3945 6.4746
MHH-CALL-4 GDSC2 3.5701 7.1776 1.5968 10.1892
DoHH2 GDSC2 3.5957 5.8132 2.2965 5.7386
Ku812 GDSC1 3.6079 5.9802 2.223 7.6791
NU-DUL-1 GDSC1; GDSC2 3.609 5.3472 2.5374 4.1924
Sc-1 GDSC1 3.6215 4.9484 2.7429 3.5895
WSU-DLCL2 GDSC1 3.6258 5.8237 2.3144 6.9087
HDLM-2 GDSC1 3.6305 5.3238 2.5651 4.9402
NALM-6 GDSC1 3.6309 5.6637 2.3975 6.2436
YT GDSC1 3.6571 5.0445 2.7214 3.6513
ALL-PO GDSC1 3.6611 5.9884 2.2597 7.2217
KY821 GDSC1 3.6645 5.1783 2.6615 4.0915
KG-1 GDSC1 3.6755 6.6418 1.9466 9.5972
HL-60 GDSC1 3.6766 5.8447 2.3426 6.528
MC116 GDSC1; GDSC2 3.6998 5.7446 2.4093 4.7683
HT GDSC1; GDSC2 3.7178 5.3969 2.593 3.5836
L-428 GDSC1 3.7193 5.659 2.4658 5.4416
HH [Human lymphoma] GDSC1 3.7405 6.2471 2.1918 7.4985
Farage GDSC1; GDSC2 3.7671 5.7019 2.4795 4.1705
KMS-12-BM GDSC1 3.7771 5.4516 2.6084 4.1767
Karpas-620 GDSC1 3.8111 6.3873 2.1754 7.4071
A4/Fukuda GDSC1 3.8201 6.0107 2.3667 5.9073
SU-DHL-8 GDSC1 3.8237 5.8537 2.446 5.2881
OCI-AML-3 GDSC1 3.8268 6.2119 2.2731 6.6076
CESS GDSC1 3.837 6.0564 2.3566 5.9354
EHEB GDSC1 3.8581 7.4811 1.6705 11.091
Granta-519 GDSC1 3.8675 6.8031 2.0124 8.4843
RCH-ACV GDSC1; GDSC2 3.8689 6.1843 2.3171 4.9368
ST486 GDSC1 3.9263 6.1051 2.3962 5.379
Reh GDSC1 3.9534 6.4833 2.2316 6.5555
BALL-1 GDSC1 3.9559 5.7672 2.5787 3.9234
P30/OHK GDSC1 3.9569 7.0357 1.964 8.5807
WIL2 NS GDSC1 3.9736 6.0766 2.4426 4.8984
PF-382 GDSC1 3.9754 6.1158 2.4249 5.0274
QIMR-WIL GDSC1; GDSC2 3.9988 6.136 2.4312 3.9486
THP-1 GDSC1; GDSC2 4.0341 5.6052 2.7051 2.2557
VAL GDSC1 4.0949 7.0026 2.0792 7.3083
MM1.S GDSC1 4.1666 6.423 2.4062 4.6726
KM-H2 GDSC1 4.2069 6.075 2.5944 3.2136
ALL-SIL GDSC1 4.2576 6.0383 2.6416 2.7756
ML-2 GDSC1 4.3786 6.7394 2.393 4.2643
SUP-B15 GDSC1 4.4929 6.909 2.3849 4.0681
RPMI-6666 GDSC1 4.5092 8.9393 1.4307 10.8623
VL51 GDSC1 4.537 6.4719 2.6072 2.4704
LP-1 GDSC1; GDSC2 4.568 7.1187 2.3341 3.4247
MOLT-13 GDSC1 4.6 6.6674 2.556 2.6904
P31/FUJ GDSC1 4.6398 5.8761 2.9055 0.6453
ME1 GDSC1 4.7664 6.554 2.6918 1.5915
P12-Ichikawa GDSC1 4.7725 6.5569 2.6937 1.5729
Jurkat GDSC1 4.7755 6.5568 2.6952 1.5601
SU-DHL-4 GDSC1; GDSC2 4.8133 6.8485 2.5917 1.6934
CA46 GDSC1 4.9614 9.1556 1.6321 8.2755
ARH-77 GDSC1 5.0515 8.5987 1.9477 5.8957
OCI-M1 GDSC1 5.1002 6.5455 2.8443 0.5329
SUP-T1 GDSC1 5.1343 6.834 2.7494 0.887
IM-9 GDSC1 5.3052 6.9904 2.7619 0.6963
DB GDSC1 5.3643 7.2999 2.669 1.0337
Karpas-422 GDSC1 5.368 6.7367 2.8786 0.2864
RC-K8 GDSC1 5.3942 6.7671 2.8776 0.2783
P32/ISH GDSC1 5.4401 6.5325 2.9738 0.0872
ROS-50 GDSC1; GDSC2 5.4843 7.853 2.5045 1.3654
MN-60 GDSC1 5.5678 7.7925 2.5664 1.307
SK-MM-2 GDSC1 5.6783 7.1934 2.8327 0.2783
Raji GDSC1 5.6914 12.3145 0.6139 12.9571
EB2 GDSC1 5.7497 7.3804 2.7935 0.3457
LC4-1 GDSC1 6.1191 7.9684 2.7235 0.3724
OCI-AML-5 GDSC1 6.3203 14.5543 -0.035 14.9567
⏷ Show the Full List of 164 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC1 2.7906 4.1444 2.4135 9.3535
KYSE-220 GDSC1 2.8028 5.9507 1.5533 15.8532
SK-GT-4 GDSC1 2.9943 6.031 1.6855 14.0766
TE-12 GDSC1; GDSC2 3.4102 6.4958 1.8079 9.3214
KYAE-1 GDSC1 3.4422 5.0104 2.5757 5.4639
FLO-1 GDSC1 3.5017 5.5274 2.3652 6.9177
ESO-26 GDSC1 3.9246 5.9109 2.4888 4.6815
ESO-51 GDSC1 3.9734 6.1564 2.404 5.1906
OACP4 C GDSC1 4.0721 7.5985 1.772 9.6743
HCE-4 GDSC1; GDSC2 4.4719 6.4852 2.5647 2.3059
OACM5.1 C GDSC1 6.1155 8.0257 2.702 0.4286
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 2.6776 4.8337 1.9794 13.1714
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-13 GDSC1 1.8283 4.4758 1.2779 22.4318
SJNB-14 GDSC1 2.6364 5.6438 1.5497 16.5933
Kelly GDSC1 2.678 4.9971 1.9017 13.7611
SK-N-DZ GDSC1 2.6972 5.565 1.6451 15.6186
GI-ME-N GDSC1 2.8344 6.2936 1.4125 16.7568
CHP-212 GDSC1 2.9749 3.985 2.6702 6.5518
CHP-126 GDSC1; GDSC2 2.9804 5.052 2.158 8.4261
NH-12 GDSC1 3.044 5.5811 1.9531 11.828
SK-N-AS GDSC1 3.0661 4.45 2.5327 7.2174
SK-N-SH GDSC1 3.1914 4.9477 2.3979 7.7738
GOTO GDSC1 3.2193 5.3457 2.2233 9.0405
SK-N-MC-IXC GDSC1; GDSC2 3.3418 5.3055 2.3467 6.1168
NB69 GDSC1 3.3794 4.6936 2.6834 4.832
TGW GDSC1 3.4054 5.1294 2.4868 6.2896
SJNB-17 GDSC1; GDSC2 3.4376 5.2753 2.4399 5.2571
SJNB-10 GDSC1 3.5329 5.2851 2.5102 5.6774
KP-N-YS GDSC2 3.5415 6.9051 1.7099 9.5663
SK-N-FI GDSC1 3.5626 6.4248 1.9663 9.8222
SiMa GDSC1 3.5681 5.4473 2.4568 5.9816
SK-N-BE(2)-M17 GDSC1 3.6445 7.4812 1.5046 13.0209
MHH-NB-11 GDSC2 3.706 6.7607 1.9112 7.8675
NB1 GDSC1 3.7562 5.5764 2.5329 4.8151
KP-N-RT-BM-1 GDSC2 4.0884 7.3365 1.912 6.9197
SJNB-12 GDSC1 4.1505 6.4757 2.3706 4.976
LA-N-6 GDSC1; GDSC2 4.1984 6.3984 2.4384 3.5
SJNB-5 GDSC1; GDSC2 4.454 6.3908 2.5967 2.1617
SJNB-6 GDSC1; GDSC2 4.7623 6.4319 2.7402 1.0672
IMR-5 GDSC1 4.8094 6.7524 2.6304 1.8852
SJNB-7 GDSC1 5.2886 12.8016 0.1043 16.8213
NB(TU)1 GDSC1 5.9777 7.9528 2.6757 0.5707
KP-N-YN GDSC1 6.321 8.5035 2.6095 0.5917
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 2.7881 4.2477 2.3633 9.7449
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-231 GDSC1 1.6735 3.7038 1.4059 22.3868
CAL-51 GDSC1 1.9091 3.6069 1.6938 19.097
MDA-MB-330 GDSC2 2.0232 6.655 0.4793 21.8233
HCC2157 GDSC1 2.4521 5.7421 1.3278 19.0295
AU565 GDSC1 2.48 6.1061 1.1782 19.9569
MCF-7 GDSC1 2.4857 3.9416 2.1885 12.5169
HCC2218 GDSC1; GDSC2 2.6068 4.4836 2.0741 10.2591
OCUB-M GDSC1 2.7928 4.7995 2.1063 11.6894
HCC1954 GDSC1 2.8668 5.2597 1.9518 12.5616
Evsa-T GDSC1 3.1085 5.1361 2.2314 9.4037
MDA-MB-453 GDSC1 3.1786 4.7403 2.49 7.0992
BT-549 GDSC1 3.1904 4.7109 2.515 6.8569
HCC1187 GDSC1 3.2503 7.4988 1.1735 16.808
HCC1806 GDSC1 3.2548 4.4827 2.6847 5.2738
CAL-120 GDSC1 3.2739 4.996 2.4445 7.0956
HDQ-P1 GDSC1 3.3088 4.9975 2.4731 6.7416
COLO 824 GDSC1 3.3098 5.0977 2.4239 7.1255
JIMT-1 GDSC1 3.3417 4.246 2.8762 3.4441
HCC1937 GDSC1 3.3774 5.5949 2.2313 8.398
MDA-MB-175-VII GDSC1 3.3791 5.1931 2.4335 6.8015
MDA-MB-361 GDSC1 3.3902 4.9007 2.5887 5.5398
CAL-85-1 GDSC1 3.3929 4.7592 2.6615 4.9571
DU4475 GDSC1 3.4293 5.0604 2.5405 5.7851
BT-474 GDSC1 3.4459 6.0497 2.0599 9.4976
MDA-MB-468 GDSC1 3.5253 4.7523 2.7684 3.6822
HCC1428 GDSC1 3.5714 5.3245 2.5202 5.475
HCC70 GDSC1 3.5813 5.1391 2.6194 4.6689
ZR-75-30 GDSC1 3.662 5.6819 2.412 6.0332
HCC1569 GDSC1; GDSC2 3.6742 7.4432 1.547 10.2128
BT-20 GDSC1 3.7132 6.745 1.9245 9.6438
MDA-MB-157 GDSC1 3.7388 6.7586 1.9374 9.4617
EFM-192A GDSC1 3.7515 5.7925 2.4238 5.6702
HCC38 GDSC1 3.7655 5.6251 2.5158 4.9192
HCC1143 GDSC1 3.8505 5.8393 2.4719 5.0138
Hs 578T GDSC1 3.9203 6.1113 2.389 5.4501
T-47D GDSC1 4.1203 7.5669 1.8224 9.1574
EFM-19 GDSC1 4.1206 5.9395 2.6038 3.3405
UACC-893 GDSC1; GDSC2 4.1966 7.5949 1.8632 6.9676
MFM-223 GDSC1 4.224 6.4898 2.4119 4.4903
CAMA-1 GDSC1 4.2654 6.8312 2.2775 5.3743
HCC1419 GDSC1 4.5487 6.115 2.7667 1.4665
HCC1395 GDSC1 4.6045 6.6565 2.5632 2.6349
HCC1599 GDSC2 4.6793 7.2179 2.3552 3.1201
MDA-MB-436 GDSC1 4.7251 6.6337 2.6375 1.9685
MRK-nu-1 GDSC1 5.0258 9.1196 1.6902 7.7211
BT-483 GDSC1 5.4317 6.7057 2.9124 0.1881
YMB-1-E GDSC2 5.4899 7.5636 2.6214 0.9075
HCC1500 GDSC1 5.5702 7.2712 2.7644 0.5162
HCC202 GDSC1 5.7148 8.0673 2.524 1.3597
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-118MG GDSC1 1.9453 3.5119 1.7637 18.4141
Becker GDSC1 2.2566 3.735 2.0251 14.8868
U-251MG GDSC1 2.2868 3.2467 2.2119 13.4269
Daoy GDSC1 2.3306 3.5493 2.1704 13.4645
KALS-1 GDSC1 2.3399 3.6745 2.1367 13.651
MOG-G-UVW GDSC1 2.3878 3.9692 2.0742 13.8478
D-566MG GDSC1; GDSC2 2.5798 3.85 2.325 8.8657
SF126 GDSC1; GDSC2 2.679 4.5917 2.0951 9.8635
LN-405 GDSC1 2.7105 7.2702 0.8177 21.3547
GaMG GDSC1 2.7561 3.9719 2.4562 9.1978
42-MG-BA GDSC1 2.832 3.5102 2.7261 6.8423
ONS-76 GDSC1 2.8475 5.0584 2.0324 12.0224
D-423MG GDSC1; GDSC2 2.8686 5.6433 1.7647 11.2549
T98G GDSC1 2.8824 3.7119 2.6993 6.7762
D-336MG GDSC1; GDSC2 2.9114 4.9649 2.1374 8.7846
GI-1 GDSC1 2.9188 4.5425 2.35 9.2618
LN-18 GDSC1 2.9301 3.9325 2.6501 6.9121
YKG-1 GDSC1; GDSC2 2.9351 4.8983 2.192 8.3638
GB-1 GDSC1 2.9418 6.8266 1.2436 17.5269
8-MG-BA GDSC1 2.955 3.8137 2.7291 6.1995
SW1783 GDSC1 2.9607 4.3283 2.4932 7.9733
SF539 GDSC1 2.9953 3.9789 2.693 6.2851
SF268 GDSC1 3.0045 5.2828 2.0658 11.1118
SF295 GDSC1; GDSC2 3.0651 4.7791 2.3696 6.8203
SW1088 GDSC1 3.1365 4.2406 2.7002 5.6191
YH-13 GDSC1 3.2644 4.1784 2.8448 3.9765
KS-1 [Human Krukenberg tumour] GDSC1 3.2757 4.9518 2.4681 6.9026
A-172 GDSC1 3.321 5.6255 2.1694 9.0863
Hs 683 GDSC1; GDSC2 3.4051 4.7193 2.6913 3.7578
D-263MG GDSC1 3.4119 4.4582 2.8269 3.5905
PFSK-1 GDSC1 3.4153 5.8985 2.1106 9.2094
AM-38 GDSC1 3.4225 5.5472 2.2919 7.7633
MOG-G-CCM GDSC1 3.4415 4.8328 2.6637 4.7741
M059J GDSC1 3.4567 4.9588 2.6129 5.1221
D-392MG GDSC1 3.4697 5.7211 2.2431 7.9834
LN-229 GDSC1 3.4767 4.6639 2.7751 3.7834
LNZTA3WT4 GDSC1 3.4872 6.1287 2.0538 9.4016
SK-MG-1 GDSC1 3.532 5.9108 2.1981 8.1245
D283 Med GDSC1 3.587 5.7558 2.3182 7.004
Onda 11 GDSC1; GDSC2 3.6256 7.0481 1.7054 9.364
D-542MG GDSC1; GDSC2 3.7626 5.4023 2.6222 3.3011
H4 GDSC1 3.8071 5.6274 2.5442 4.583
CAS-1 GDSC1 3.8616 5.7727 2.5119 4.6776
DK-MG GDSC1 3.9164 5.9042 2.4864 4.7217
U-87MG ATCC GDSC1 4.0292 5.9704 2.5306 4.0959
KNS-81-FD GDSC1; GDSC2 4.0837 7.4746 1.8412 7.3644
DBTRG-05MG GDSC1 4.1597 5.7241 2.7264 2.3915
KINGS-1 GDSC1 4.1807 8.4058 1.4553 11.6493
NMC-G1 GDSC1; GDSC2 4.2013 7.1478 2.083 5.6222
Onda 10 GDSC1; GDSC2 4.2755 6.2752 2.5441 2.7455
D-247MG GDSC1; GDSC2 4.28 6.1144 2.6203 2.3093
KNS-42 GDSC1; GDSC2 4.5233 7.5615 2.1002 4.8559
D-245MG GDSC2 4.6789 9.3546 1.3479 8.9565
D-502MG GDSC1; GDSC2 4.9362 7.5484 2.3541 2.73
SNB-75 GDSC1; GDSC2 4.985 8.1295 2.122 3.9049
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 3.3003 5.0987 2.4154 7.2273
TGBC24TKB GDSC1 3.3937 5.1665 2.4587 6.5519
TGBC1TKB GDSC1 4.4612 7.1941 2.233 5.2228
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC1 3.1073 4.8097 2.3924 8.1467
MFE-319 GDSC1 3.427 5.2206 2.4586 6.437
ESS-1 GDSC1 3.5206 4.8839 2.6997 4.2333
EN GDSC1 3.6486 5.2842 2.598 4.63
MFE-296 GDSC1 3.7638 7.3259 1.6752 11.3621
KLE GDSC1 4.6997 7.5092 2.2346 4.6726
MFE-280 GDSC1 6.4441 8.3958 2.6931 0.3255
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O GDSC1 2.3519 12.4928 -2.0951 34.9914
RXF 393L GDSC1; GDSC2 2.6061 5.2915 1.6915 12.6052
BFTC-909 GDSC1 2.6066 4.8278 1.9132 13.9946
UO-31 GDSC1; GDSC2 2.8909 4.7208 2.2373 8.2323
ACHN GDSC1 3.0724 4.707 2.4118 8.1351
KTCTL-140 GDSC1; GDSC2 3.1099 4.7255 2.4365 6.2546
SN12C GDSC1 3.2984 5.7774 2.0746 9.9109
CAL-54 GDSC1 3.3037 4.9821 2.4766 6.7324
KTCTL-195 GDSC1 3.3505 4.817 2.598 5.6064
KMRC-20 GDSC1 3.3958 4.4771 2.8047 3.8194
TK-10 GDSC1 3.4207 4.9393 2.594 5.3931
NCC010 GDSC1; GDSC2 3.4281 5.465 2.3375 5.931
769-P GDSC1 3.4369 4.5268 2.8124 3.6209
KTCTL-26A GDSC1; GDSC2 3.5692 5.3649 2.4985 4.5376
SW13 GDSC1 3.5755 6.5802 1.899 10.2963
KMRC-1 GDSC1 3.5913 4.9269 2.7314 3.7677
A-498 GDSC1 3.7687 5.5662 2.5468 4.6723
SW156 GDSC1; GDSC2 3.7706 5.4231 2.6177 3.3112
NCC021 GDSC1; GDSC2 3.846 9.1302 0.8422 13.9355
BB65-RCC GDSC1; GDSC2 4.0159 6.4245 2.304 4.6844
LB2241-RCC GDSC1; GDSC2 4.0425 6.3897 2.3391 4.4133
LB1047-RCC GDSC1; GDSC2 4.0585 6.1292 2.4745 3.5638
OS-RC-2 GDSC1 4.3124 6.0311 2.6766 2.4283
KTCTL-13 GDSC1; GDSC2 4.4204 6.1145 2.6999 1.6682
KTCTL-21 GDSC1; GDSC2 4.4835 7.4965 2.1051 4.9051
VMRC-RCW GDSC2 4.6229 7.3391 2.2662 3.7133
RCC10RGB GDSC1 4.6845 7.05 2.4337 3.3415
Caki-1 GDSC1; GDSC2 4.8554 9.7741 1.2671 9.0381
VMRC-RCZ GDSC1 4.9236 8.0346 2.1288 4.9288
HA7-RCC GDSC1; GDSC2 5.6161 7.4729 2.7087 0.5437
KTCTL-1M GDSC1; GDSC2 5.6675 7.7023 2.644 0.7103
LB996-RCC GDSC1 6.0909 8.1588 2.6451 0.6046
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 116 GDSC1 2.2359 3.9943 1.9035 15.865
HCT 15 GDSC1 2.3015 5.6012 1.2503 20.2737
SW48 GDSC1 2.3961 4.8683 1.6868 16.6673
LS513 GDSC1 2.8361 3.8696 2.5832 7.8631
SW620 GDSC1; GDSC2 2.8411 4.7439 2.1791 8.7665
KM12 GDSC1 2.882 5.5745 1.8109 13.58
HT-55 GDSC1 2.9913 5.2698 2.0604 11.2076
MDST8 GDSC1 3.0006 4.4686 2.4628 8.0367
COLO 320HSR GDSC1 3.0224 4.5421 2.4472 8.0655
LoVo GDSC1 3.1037 6.1184 1.738 13.2465
CW-2 GDSC1 3.2042 4.9825 2.3916 7.7743
NCI-H716 GDSC1 3.3734 4.9587 2.546 5.935
CCK-81 GDSC1 3.4349 4.8946 2.6277 5.0796
LS411N GDSC1 3.5 4.6177 2.8158 3.3916
SK-CO-1 GDSC1 3.5322 5.0428 2.6299 4.7421
SNU-C2B GDSC1 3.5397 5.1913 2.562 5.2493
COLO 678 GDSC1 3.675 6.287 2.1224 8.2434
RKO GDSC1 3.7404 6.9515 1.843 10.176
SNU-407 GDSC1 3.82 5.3129 2.7047 3.332
C2BBe1 GDSC1 3.8808 6.117 2.3583 5.7964
NCI-H747 GDSC1 3.8982 5.8275 2.5108 4.5864
SW1417 GDSC1 3.9389 6.4225 2.2508 6.4508
HT115 GDSC1; GDSC2 4.0695 5.8528 2.612 2.7292
CL-11 GDSC1 4.1097 5.8828 2.6233 3.2246
LS180 GDSC1 4.1108 6.2733 2.4406 4.5577
SW626 GDSC1 4.1441 7.2203 2.0082 7.7031
LS1034 GDSC1 4.1765 5.7823 2.7099 2.4706
RCM-1 [Human ESC] GDSC1 4.2069 7.5893 1.8732 8.5314
LS123 GDSC1 4.3983 6.2647 2.6213 2.6342
SNU-283 GDSC2 4.4224 6.2987 2.6198 2.086
CaR-1 GDSC1 4.4327 7.2423 2.1921 5.5867
SW837 GDSC1 4.4805 7.1328 2.2737 4.8848
DiFi GDSC1 4.7517 7.32 2.3513 3.7645
SW1116 GDSC1 4.8127 11.1475 0.5712 15.5383
T84 GDSC1 4.8704 11.5894 0.3969 16.382
HT-29 GDSC1; GDSC2 4.9159 6.3357 2.8472 0.5281
GP5d GDSC1 5.1725 6.8236 2.7697 0.7682
SNU-61 GDSC1 5.3398 7.2349 2.6835 0.9919
COLO205 GDSC1 5.4037 6.7598 2.8836 0.2601
SW1463 GDSC1 5.4594 6.956 2.8352 0.3613
SW948 GDSC1 5.5075 6.8841 2.8782 0.2356
NCI-H508 GDSC1; GDSC2 5.6343 8.2533 2.413 1.6058
SNU-C5 GDSC1 5.7481 7.8696 2.6143 0.9403
SNU-81 GDSC1; GDSC2 5.7781 7.9789 2.5854 0.8303
SNU-C1 GDSC1 5.9655 7.9185 2.6834 0.5535
HCC2998 GDSC1 6.1031 14.3484 -0.0812 15.7017
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 2.3317 4.1655 1.9339 15.1554
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2/C3A GDSC1 2.8519 4.6771 2.2215 10.5444
SNU-398 GDSC1 3.035 4.7356 2.3638 8.6636
JHH-2 GDSC1 3.0478 4.5807 2.4517 7.9252
SNU-423 GDSC1 3.2137 5.0851 2.3486 8.0766
SK-HEP-1 GDSC1 3.3638 5.1787 2.4282 6.8981
HuH-1 GDSC1 3.3906 4.9452 2.5668 5.711
JHH-7 GDSC1 3.4871 5.4302 2.4021 6.6773
Hep 3B2.1-7 GDSC1; GDSC2 3.5378 5.0543 2.6284 3.8017
JHH-6 GDSC1 3.5658 5.5605 2.3989 6.4417
SNU-449 GDSC1 3.5706 5.1687 2.5967 4.8794
Huh-7 GDSC1 3.5934 5.0948 2.6503 4.3914
HLE GDSC1 3.8818 5.7083 2.5569 4.2815
SNU-387 GDSC1 3.9894 5.6288 2.666 3.1964
JHH-1 GDSC1 4.2189 6.4827 2.4119 4.5018
JHH-4 GDSC1 7.0642 15.0915 0.1864 12.21
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 185 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H3122 GDSC1 0.6144 2.8784 0.4753 34.6675
NCI-H1975 GDSC1 1.7366 3.9894 1.3727 22.2673
A-549 GDSC1 2.0694 5.5566 1.0437 22.8049
NCI-H460 GDSC1; GDSC2 2.1451 3.7523 1.8989 13.1485
PC-14 GDSC1; GDSC2 2.1717 4.6492 1.5595 15.0219
NCI-H1341 GDSC1 2.188 4.3454 1.7081 17.5249
NCI-H1755 GDSC1 2.2074 12.5479 -2.2499 35.9025
HCC827 GDSC1 2.2483 4.7306 1.6012 18.0052
NCI-H2023 GDSC1 2.2862 3.7542 2.0499 14.5535
NCI-H2030 GDSC1; GDSC2 2.356 5.9612 1.1307 16.8952
NCI-H1963 GDSC1 2.4324 3.7023 2.226 12.5234
NCI-H1993 GDSC1 2.49 11.3769 -1.4182 32.5746
EBC-1 GDSC1 2.5157 4.3834 2.0281 13.5541
NCI-H1437 GDSC1; GDSC2 2.5673 5.6077 1.5021 13.9035
NCI-H1944 GDSC1 2.5719 4.6085 1.9816 13.6375
SHP-77 GDSC1 2.5825 8.208 0.2382 25.3128
RERF-LC-MS GDSC1; GDSC2 2.6011 5.6282 1.5242 13.6504
NCI-H1155 GDSC1 2.6509 4.3342 2.1867 11.7215
COR-L23 GDSC1 2.6526 4.1306 2.2802 11.0118
NCI-H647 GDSC1; GDSC2 2.6603 4.7826 1.9869 10.5951
NCI-H720 GDSC1 2.6738 3.8911 2.4062 9.9743
NCI-H1915 GDSC1 2.7218 3.7395 2.5196 8.902
Lu-135 GDSC1 2.7818 4.48 2.2483 10.6495
NCI-H1568 GDSC1 2.8066 4.8708 2.085 11.7931
NCI-H2170 GDSC1 2.8069 5.4412 1.8075 13.9207
EPLC-272H GDSC1 2.8234 6.0313 1.5322 15.9236
NCI-H810 GDSC1 2.8753 6.3028 1.4447 16.3533
NCI-H23 GDSC1 2.895 4.7146 2.2442 10.1821
CAL-12T GDSC1; GDSC2 2.9398 6.4033 1.4522 12.9617
Lu-99A GDSC1 2.9655 4.7093 2.3126 9.3517
NCI-H1792 GDSC1 2.9934 6.5634 1.4199 16.0542
Calu-6 GDSC1 3.0013 4.6668 2.3666 8.7813
NCI-H1048 GDSC1 3.0084 5.9522 1.7372 13.6285
A-427 GDSC1; GDSC2 3.0321 4.6953 2.3809 6.858
HARA [Human squamous cell lung carcinoma] GDSC1 3.0706 5.1705 2.1807 9.9503
SK-MES-1 GDSC1 3.0719 4.2996 2.6118 6.5768
NCI-H510A GDSC1; GDSC2 3.072 4.038 2.739 4.4881
NCI-H2461 GDSC1 3.0976 4.6598 2.4579 7.6727
Lu-134-A GDSC1; GDSC2 3.1372 5.2361 2.2068 7.6161
NCI-H2122 GDSC1 3.1399 3.904 2.8681 4.2979
NCI-H2795 GDSC1 3.1923 4.8167 2.464 7.2505
NCI-H596 GDSC1 3.2061 5.2538 2.2579 8.8184
SK-LU-1 GDSC1 3.2105 5.4935 2.1419 9.7112
HOP-62 GDSC1 3.2124 4.3938 2.6921 5.3785
COLO 668 GDSC1 3.2493 8.1527 0.8458 19.005
LOU-NH91 GDSC1 3.2502 5.0156 2.4146 7.419
HCC78 GDSC1 3.2536 4.2452 2.8022 4.3536
HCC44 GDSC1 3.2558 4.8869 2.4837 6.8537
COR-L32 GDSC2 3.2897 5.1843 2.3638 6.1608
LCLC-103H GDSC1 3.3159 4.7303 2.6127 5.6155
NCI-H2110 GDSC1; GDSC2 3.3195 5.6609 2.1504 7.4233
NCI-H2171 GDSC2 3.3353 5.2425 2.3727 5.9709
NCI-H292 GDSC1; GDSC2 3.3517 4.9377 2.5387 4.873
NCI-H2405 GDSC1 3.354 6.4489 1.7851 11.9463
VMRC-LCD GDSC1 3.3647 4.7137 2.6614 5.0568
KNS-62 GDSC1 3.3648 4.2757 2.8803 3.3312
NCI-H2369 GDSC1 3.3744 4.3949 2.8285 3.7059
RERF-LC-KJ GDSC1 3.3858 8.2701 0.9009 18.1347
HCC15 GDSC1 3.3961 4.5177 2.7847 3.9762
NCI-H2373 GDSC1 3.4436 4.7154 2.7238 4.2947
NCI-H522 GDSC1 3.4437 5.5929 2.2863 7.7341
NCI-H2087 GDSC1 3.4442 5.6563 2.255 7.9781
NCI-H1092 GDSC1 3.4487 5.8971 2.1384 8.8751
COR-L105 GDSC1 3.4613 5.2423 2.4753 6.1887
PaCa-3 GDSC1 3.4717 6.3262 1.9427 10.3161
SBC-5 GDSC1 3.4852 5.6143 2.3088 7.4152
NCI-H358 GDSC1 3.4901 5.8418 2.1992 8.2576
NCI-H1355 GDSC1 3.4931 5.9794 2.133 8.7643
NCI-H2731 GDSC1 3.4939 4.9561 2.6434 4.7602
NCI-H661 GDSC1 3.5052 7.4334 1.4168 14.1455
NCI-H1651 GDSC1 3.5156 8.0411 1.1217 16.1859
NCI-H1299 GDSC1 3.5234 5.2305 2.5299 5.5541
SBC-3 GDSC1 3.5329 5.0909 2.6065 4.9227
CPC-N GDSC1 3.5398 5.8332 2.243 7.7473
NCI-H2228 GDSC1 3.5489 5.5789 2.3766 6.6713
NCI-H1869 GDSC1 3.5546 5.031 2.6528 4.4924
NCI-H290 GDSC1; GDSC2 3.5555 5.7977 2.2729 5.9925
NCI-H1666 GDSC1 3.5563 5.8309 2.257 7.583
NCI-H526 GDSC1 3.5591 6.281 2.0351 9.3015
NCI-H838 GDSC1; GDSC2 3.5624 5.4982 2.4272 5.0033
NCI-H2347 GDSC1 3.5719 9.7852 0.2961 21.1122
NCI-H1793 GDSC1 3.5752 7.1548 1.6123 12.4659
NCI-H1703 GDSC1 3.5882 5.3814 2.5048 5.5415
IST-SL1 GDSC1; GDSC2 3.608 5.0407 2.6877 3.2562
COR-L303 GDSC2 3.6175 5.8339 2.3029 5.6415
LC-2/ad GDSC1; GDSC2 3.6189 5.3004 2.568 3.9766
NCI-H1304 GDSC1 3.6251 5.8353 2.3081 6.9599
NCI-H1573 GDSC1 3.6477 5.8568 2.3147 6.8359
NCI-H2196 GDSC2 3.6553 5.5228 2.4854 4.4025
NCI-H520 GDSC1 3.6782 5.4786 2.5242 5.1123
LXF 289 GDSC1 3.6938 5.1241 2.7088 3.6432
NCI-H1781 GDSC1 3.7045 5.1668 2.6956 3.7145
DMS 114 GDSC1 3.7178 5.4609 2.5617 4.7049
IA-LM GDSC1 3.7369 5.3479 2.6305 4.1214
NCI-H441 GDSC1 3.7848 5.5453 2.5684 4.4612
NCI-H1693 GDSC1 3.7867 6.3527 2.1743 7.4905
NCI-H2722 GDSC1 3.7867 6.2392 2.2302 7.0596
BEN GDSC1; GDSC2 3.7888 5.6909 2.5004 3.9908
SW1271 GDSC1 3.792 5.5748 2.5592 4.5112
NCI-H2591 GDSC1 3.7933 6.3845 2.1635 7.5533
DMS 273 GDSC1 3.8127 5.7532 2.4871 5.0046
NCI-H1623 GDSC1 3.8533 7.333 1.7402 10.587
NCI-H650 GDSC1 3.8537 8.9292 0.9482 16.172
NCI-H841 GDSC1 3.8733 5.6738 2.5678 4.2224
NCI-H2595 GDSC1 3.8764 6.1566 2.3359 5.9806
LCLC-97TM1 GDSC1 3.8867 8.0494 1.4108 12.8906
NCI-H146 GDSC1; GDSC2 3.8979 6.4706 2.198 5.6047
Ms-1 GDSC1 3.9027 5.8667 2.495 4.6935
HCC33 GDSC2 3.9027 7.8883 1.5029 9.8811
DMS 53 GDSC1 3.907 6.449 2.2152 6.8156
NCI-H209 GDSC1 3.9234 6.0698 2.4113 5.2723
NCI-H2172 GDSC1; GDSC2 3.9371 5.8887 2.508 3.6152
HOP-92 GDSC1 3.9522 7.0512 1.9529 8.6787
NCI-H69 GDSC1 3.9689 6.1306 2.4134 5.132
NCI-H2009 GDSC1 3.9712 5.8673 2.5412 4.1647
UMC-11 GDSC1 3.9891 6.2245 2.382 5.3142
EMC-BAC-2 GDSC1 4.0021 5.9391 2.5276 4.1868
NCI-H2810 GDSC1; GDSC2 4.012 5.9576 2.5253 3.3548
NCI-H446 GDSC1 4.0123 5.5578 2.7136 2.7985
NCI-H2066 GDSC1 4.0152 5.7686 2.6168 3.4943
NCI-H226 GDSC1 4.0458 6.2037 2.4305 4.7988
NCI-H187 GDSC1 4.0613 5.742 2.6585 3.0823
COR-L321 GDSC1; GDSC2 4.0687 6.2366 2.4302 3.8083
NCI-H1694 GDSC1 4.1053 6.2381 2.4537 4.4746
NCI-H2085 GDSC1 4.1239 6.245 2.4625 4.3629
NCI-H196 GDSC1 4.1545 6.1764 2.5145 3.9075
NCI-H1105 GDSC2 4.1623 6.5221 2.3563 4.0581
SW1573 GDSC1 4.1624 6.3096 2.457 4.3094
NCI-H2081 GDSC1; GDSC2 4.2174 6.7333 2.2924 4.3275
Calu-3 GDSC1 4.2761 9.3974 1.0381 14.2191
NCI-H250 GDSC2 4.2833 7.9869 1.7339 7.5538
NCI-H3255 GDSC1; GDSC2 4.2946 6.7769 2.3222 3.9966
NCI-H1770 GDSC1; GDSC2 4.3181 6.1554 2.6241 2.2262
NCI-H345 GDSC1; GDSC2 4.3319 5.3589 2.9717 0.5117
NCI-H1838 GDSC1 4.3357 6.9067 2.2876 5.1275
SBC-1 GDSC1; GDSC2 4.4099 6.6292 2.4629 2.9709
NCI-H2342 GDSC1 4.4809 7.364 2.1659 5.66
ChaGo-K-1 GDSC1; GDSC2 4.4843 7.2586 2.2174 4.2459
NCI-H2141 GDSC1 4.4875 6.4771 2.5772 2.7588
NCI-H2818 GDSC1 4.5047 7.9995 1.8803 7.6709
NCI-H727 GDSC1 4.5052 7.655 2.0444 6.4802
NCI-H64 GDSC1 4.5242 6.5422 2.569 2.744
NCI-H2444 GDSC1; GDSC2 4.5763 5.8861 2.8735 0.6881
NCI-H2291 GDSC1; GDSC2 4.5853 8.4955 1.6972 7.1092
NCI-H2135 GDSC1; GDSC2 4.6217 7.1571 2.3487 3.2513
EKVX GDSC1; GDSC2 4.6588 7.6243 2.1565 4.2744
NCI-H847 GDSC1 4.6885 6.3336 2.7449 1.3985
LK-2 GDSC1 4.6984 7.0525 2.4404 3.2699
COR-L88 GDSC1 4.7071 7.783 2.1129 5.5099
NCI-H2227 GDSC1; GDSC2 4.7182 10.3166 0.9088 11.3712
Lu-139 GDSC1 4.7212 9.0745 1.5117 9.7196
NCI-H524 GDSC1 4.7796 7.3314 2.3622 3.6367
NCI-H1435 GDSC1 4.79 7.2432 2.4074 3.3164
RERF-LC-Sq1 GDSC1 4.8433 7.5309 2.3094 3.8668
NCI-H1436 GDSC1; GDSC2 4.861 6.4858 2.7646 0.8726
ABC-1 GDSC1; GDSC2 4.9021 7.3081 2.4407 2.3297
IST-SL2 GDSC1; GDSC2 4.9541 7.692 2.3005 2.9863
NCI-H322M GDSC1 4.9663 8.755 1.8229 6.9451
NCI-H740 GDSC2 4.9902 8.5437 1.9357 4.9356
NCI-H1650 GDSC1 5.025 8.0869 2.1645 4.4812
NCI-H1734 GDSC1; GDSC2 5.053 6.821 2.7187 0.8888
Lu-165 GDSC1 5.0567 6.4902 2.8473 0.5518
COR-L95 GDSC1 5.0818 6.8468 2.7215 1.0641
DMS 79 GDSC1; GDSC2 5.1219 10.3194 1.1856 8.9372
NCI-H1876 GDSC1 5.1684 7.2186 2.6128 1.5098
HCC366 GDSC1; GDSC2 5.2165 7.9444 2.3333 2.45
NCI-H1688 GDSC1 5.2491 10.6987 1.0895 11.1667
NCI-H2803 GDSC1; GDSC2 5.2566 7.2109 2.6563 0.9603
NCI-H1563 GDSC1 5.2669 6.8347 2.8044 0.5657
COR-L279 GDSC1 5.2725 11.5637 0.6915 13.5633
Lu-65 GDSC1 5.2794 7.3441 2.6138 1.3785
EMC-BAC-1 GDSC1; GDSC2 5.3037 8.6791 2.059 3.7422
LB647-SCLC GDSC1; GDSC2 5.3806 7.5596 2.5742 1.1759
NCI-H82 GDSC1 5.4031 6.993 2.8003 0.4958
NCI-H2029 GDSC1; GDSC2 5.4878 6.6632 2.9465 0.0928
NCI-H2804 GDSC1; GDSC2 5.5347 7.4672 2.6775 0.6858
NCI-H1836 GDSC1; GDSC2 5.5856 7.0203 2.8592 0.2015
NCI-H1581 GDSC1 5.5857 7.3684 2.735 0.6043
NCI-H835 GDSC1 5.7052 8.0389 2.5308 1.3376
NCI-H748 GDSC2 5.7544 7.7378 2.6663 0.5922
NCI-H513 GDSC1 5.9958 7.6833 2.7778 0.2909
NCI-H211 GDSC1 6.0198 8.1092 2.6353 0.6767
NCI-H1648 GDSC1 6.2536 8.5562 2.5641 0.7747
NCI-H2869 GDSC1; GDSC2 6.2837 7.9884 2.7757 0.1693
LC-1/sq GDSC1 6.7904 8.956 2.6243 0.3596
⏷ Show the Full List of 185 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.7673 10.4926 0.8581 13.9234
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-150 GDSC1 1.7253 3.779 1.4362 21.8915
EC-GI-10 GDSC1 1.9866 4.369 1.4881 20.1328
KYSE-510 GDSC1; GDSC2 2.0566 4.5389 1.4891 15.8941
OE21 GDSC1 2.2896 6.0889 1.006 22.0015
TE-4 GDSC1 2.3676 4.5377 1.8087 15.9006
OE19 GDSC1 2.9719 4.1803 2.5749 7.2948
TE-9 GDSC1 2.974 4.6675 2.341 9.0952
TE-15 GDSC1 2.9855 5.264 2.058 11.2497
TE-8 GDSC1 3.0172 5.8667 1.7874 13.2099
KYSE-520 GDSC1 3.0293 6.0967 1.6837 13.9509
TE-11 GDSC1; GDSC2 3.0357 4.2798 2.5876 5.5541
TE-1 GDSC1 3.0504 6.4903 1.5062 15.1947
KYSE-180 GDSC1 3.191 5.1991 2.2721 8.7639
T.T GDSC1 3.2701 4.4196 2.7293 4.8653
TE-10 GDSC1; GDSC2 3.3375 4.9206 2.5355 4.9343
OE33 GDSC1 3.3712 5.3701 2.3386 7.5769
KYSE-410 GDSC1 3.3847 5.2195 2.4249 6.8496
KYSE-450 GDSC1 3.6285 5.593 2.4307 5.9929
TE-6 GDSC1 3.7979 7.415 1.6573 11.3834
KYSE-270 GDSC1 3.9039 7.9407 1.4779 12.3534
KYSE-140 GDSC1 4.1754 7.7375 1.7787 9.3206
COLO 680N GDSC1 4.3514 8.0416 1.7552 8.9913
TE-5 GDSC1 4.7456 7.8064 2.1259 5.3325
KYSE-70 GDSC1 7.2722 17.1746 -0.654 15.7646
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC1 1.8553 5.3565 0.9216 24.6841
EFO-27 GDSC1; GDSC2 2.1161 4.9228 1.3808 16.3001
OC 314 GDSC1 2.3158 3.508 2.168 13.5628
OVCAR-8 GDSC1 2.3234 3.1217 2.2796 12.7636
DOV13 GDSC1 2.8736 5.0952 2.0386 11.8635
OVTOKO GDSC1 2.9998 4.7619 2.3185 9.1623
Caov-3 GDSC2 3.0618 5.1018 2.2069 7.8541
TOV-112D GDSC1 3.1821 4.4885 2.6184 6.0765
TYK-nu GDSC1 3.2316 4.5722 2.6201 5.8711
OVCAR-5 GDSC1 3.2434 4.8107 2.5111 6.6848
OVCAR-3 GDSC1 3.2529 4.4261 2.7113 5.072
TOV-21G GDSC1 3.3851 5.1175 2.4762 6.444
ES-2 GDSC1 3.4147 4.8469 2.6353 5.0882
OV56 GDSC1 3.5426 6.1194 2.1026 8.833
OVK18 GDSC1; GDSC2 3.5488 5.742 2.2953 5.8692
FU-OV-1 GDSC1 3.6 5.1331 2.6363 4.4796
SK-OV-3 GDSC1 3.6536 5.3812 2.5539 4.9565
Kuramochi GDSC1 3.6764 9.0615 0.7419 18.1031
OAW42 GDSC1 3.6954 6.1577 2.202 7.5606
JHOS-2 GDSC1; GDSC2 3.8926 5.3175 2.7502 2.2582
IGROV-1 GDSC1 4.0585 7.1294 1.9917 8.072
OVCAR-4 GDSC1 4.1087 6.4032 2.3773 5.033
OVISE GDSC1 4.2233 6.3607 2.4719 4.0546
JHOS-4 GDSC1; GDSC2 4.4454 8.6548 1.5238 8.4447
EFO-21 GDSC1 4.4707 6.5536 2.5333 3.0869
Caov-4 GDSC1 4.5631 6.5696 2.5786 2.6093
OVKATE GDSC1 4.5824 6.5326 2.6054 2.4014
OAW28 GDSC1 4.6051 7.4399 2.2087 5.0636
OV-90 GDSC1 4.8686 6.9259 2.5872 2.052
RMG-I GDSC1 6.2426 8.0432 2.7424 0.2861
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PSN1 GDSC1 2.0712 3.6971 1.8388 17.1996
MIA PaCa-2 GDSC1 2.1555 3.8497 1.874 16.4983
HPAF-II GDSC1 2.7013 4.451 2.1829 11.5155
PaTu 8988t GDSC1 2.8785 4.6239 2.2725 10.035
KP-3 GDSC1 3.0426 5.8933 1.7966 13.0388
Panc 02.03 GDSC1 3.1109 5.5994 2.0029 11.1783
KP-4 GDSC1 3.1298 4.3343 2.6479 6.0556
Panc 03.27 GDSC1 3.1634 4.2323 2.7287 5.2865
CFPAC-1 GDSC1 3.2544 5.9397 1.9563 10.994
KP-1N GDSC1 3.2695 5.0073 2.4351 7.1857
SW1990 GDSC1 3.3646 4.6862 2.675 4.9501
SU.86.86 GDSC1 3.4385 4.8845 2.6355 5.0058
YAPC GDSC1 3.5385 4.8518 2.7292 3.9468
Panc 04.03 GDSC1 3.6211 7.2542 1.5992 12.4052
PaTu 8902 GDSC1 3.6282 5.5257 2.4637 5.7365
Panc 10.05 GDSC1 3.6875 5.1479 2.6927 3.7848
HuP-T3 GDSC1 3.7517 7.2851 1.6861 11.3203
PL4 GDSC1 3.8923 5.7014 2.5674 4.1739
MZ-PC-1 GDSC1; GDSC2 4.137 6.2519 2.4678 3.4467
HuP-T4 GDSC1 4.1961 6.2967 2.4847 4.0261
Hs 766T GDSC1 4.2476 5.983 2.6607 2.6638
QGP-1 GDSC1; GDSC2 4.4525 10.4472 0.652 13.4234
DAN-G GDSC1 4.4843 9.3175 1.229 12.3188
AsPC-1 GDSC1 4.5736 6.7382 2.5097 3.0457
HPAC GDSC1 4.6746 10.6323 0.7236 15.0222
Capan-2 GDSC1 4.6896 6.7584 2.5651 2.4739
SUIT-2 GDSC1 4.9347 6.424 2.8214 0.7504
Panc 08.13 GDSC1 5.0103 8.5854 1.9287 6.1156
Capan-1 GDSC1 5.7326 8.1837 2.4862 1.5192
KP-2 GDSC1 5.8074 7.105 2.9082 0.1089
BxPC-3 GDSC1 5.9095 8.1516 2.575 0.9717
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1 2.9144 4.6421 2.2976 9.6863
MPP 89 GDSC1 3.8477 5.5134 2.6274 3.8406
NCI-H2452 GDSC1 3.8886 5.7209 2.5556 4.2734
NCI-H2052 GDSC1 4.0036 5.6788 2.6516 3.2673
IST-Mes1 GDSC1 4.6219 6.332 2.7125 1.6776
MSTO-211H GDSC1 5.8176 7.4397 2.7978 0.3087
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC1 2.9013 4.6403 2.2861 9.8308
PC-3 GDSC1 3.0589 4.5661 2.4691 7.7433
LNCaP clone FGC GDSC1 3.4649 5.9197 2.1402 8.8055
22Rv1 GDSC1 4.5371 9.123 1.3611 11.2651
NCI-H660 GDSC2 4.8357 6.1586 2.8807 0.4701
VCaP GDSC1 5.3762 7.0275 2.777 0.5916
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 3.5933 5.5643 2.4181 6.2032
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-375 GDSC1; GDSC2 1.8452 3.2622 1.7262 15.4434
A2058 GDSC1 2.2054 3.4134 2.0773 14.8037
RPMI-7951 GDSC1 2.5482 3.8478 2.2925 11.4408
IGR-1 GDSC1 2.6146 3.7465 2.4034 10.2961
IST-MEL1 GDSC1 2.732 4.1937 2.3322 10.2424
DJM-1 GDSC1; GDSC2 2.9035 4.432 2.3887 7.2492
LOX-IMVI GDSC1 2.9727 4.95 2.2012 10.1881
CHL-1 GDSC1 2.9817 4.2196 2.5655 7.3243
IGR-37 GDSC1 3.004 4.5402 2.4311 8.268
WM278 GDSC1 3.0271 5.8716 1.7938 13.122
G-mel GDSC1; GDSC2 3.0608 4.613 2.4476 6.3449
MeWo GDSC1 3.0707 4.837 2.3461 8.6563
WT2-iPS GDSC1; GDSC2 3.1807 4.4225 2.6499 4.6839
IPC-298 GDSC1; GDSC2 3.2831 4.6237 2.6385 4.4415
SK-MEL-28 GDSC1; GDSC2 3.3312 4.4736 2.7538 3.5706
WM793 GDSC1 3.3421 5.4216 2.2889 8.0719
Hs 938.T GDSC1; GDSC2 3.4017 4.7165 2.69 3.7752
SK-MEL-30 GDSC1; GDSC2 3.424 4.4142 2.8584 2.6513
A-431 GDSC1; GDSC2 3.4517 5.335 2.4214 5.3357
MZ-MEL-2 GDSC1; GDSC2 3.4698 4.9026 2.6512 3.8357
HT-144 GDSC1 3.4853 4.8345 2.6971 4.3674
COLO 679 GDSC1 3.4857 4.978 2.6261 4.9223
Mel Ho GDSC1; GDSC2 3.4935 4.7675 2.7367 3.2358
UACC-62 GDSC1 3.5219 4.864 2.7106 4.144
Mel JuSo GDSC1 3.543 6.1356 2.0948 8.8921
SK-MEL-2 GDSC1 3.5606 6.2321 2.0606 9.0989
451Lu GDSC1; GDSC2 3.5612 5.6247 2.3634 5.408
CP50-MEL-B GDSC1; GDSC2 3.5786 4.9924 2.6898 3.3152
A101D GDSC1 3.6134 4.793 2.8128 3.0746
COLO 829 GDSC1 3.6201 6.0035 2.2209 7.6555
SH-4 GDSC1 3.6483 5.3862 2.5476 5.0217
WM115 GDSC1 3.7332 5.7635 2.4247 5.7177
WM1552C GDSC1 3.7374 5.1602 2.7218 3.4233
HMV-II GDSC1 3.7415 6.1044 2.263 6.9441
RVH-421 GDSC1; GDSC2 3.8364 5.8401 2.4615 4.1212
MZ-MEL-7 GDSC1; GDSC2 3.8435 5.4925 2.6345 3.049
G-361 GDSC1 3.8639 6.0245 2.3914 5.5914
LB2518-MEL GDSC1; GDSC2 3.935 5.3393 2.7669 2.0802
SK-MEL-24 GDSC1 3.9403 5.4812 2.7039 3.0369
A-388 GDSC1; GDSC2 4.0178 6.8346 2.1063 5.8908
COLO 800 GDSC1; GDSC2 4.0911 6.746 2.2008 5.1479
COLO 792 GDSC1 4.1377 5.8808 2.6415 3.0315
SK-MEL-31 GDSC1; GDSC2 4.1651 5.7794 2.7045 2.0324
MMAc-SF GDSC1; GDSC2 4.5062 6.2753 2.6763 1.6707
VMRC-MELG GDSC1; GDSC2 4.5919 6.3615 2.6845 1.518
WM35 GDSC1 4.5955 6.419 2.6617 2.0247
CP66-MEL GDSC1; GDSC2 4.5975 6.3216 2.7044 1.4147
GAK GDSC1 4.7399 7.2637 2.3697 3.6633
M14 GDSC1 4.7678 6.6547 2.6504 1.8283
SK-MEL-5 GDSC1; GDSC2 4.9695 6.3124 2.878 0.4006
COLO 783 GDSC2 5.0177 7.4356 2.4472 2.1427
LB373-MEL-D GDSC1; GDSC2 5.0619 6.2793 2.926 0.2355
SK-MEL-3 GDSC1; GDSC2 5.219 9.0632 1.8359 5.0941
Hs 940.T GDSC1; GDSC2 5.2256 6.7615 2.8148 0.4461
SK-MEL-1 GDSC1 5.3932 7.094 2.7592 0.6443
UACC-257 GDSC1 5.5559 8.7682 2.158 3.5717
EquiPSC Line K2 GDSC1; GDSC2 5.5606 7.436 2.6999 0.6002
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 3.0202 4.3949 2.5171 6.0465
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1080 GDSC1 1.6186 3.3566 1.4535 22.3738
SK-UT-1 GDSC1 2.2383 4.5833 1.6567 17.6488
SK-LMS-1 GDSC1 2.3221 4.3991 1.8236 16.0126
Hs 633.T GDSC1 2.3991 3.8455 2.1356 13.3454
GCT GDSC1 2.841 3.733 2.6472 7.3663
MFH-ino GDSC1 2.9306 4.205 2.5232 7.8762
SW872 GDSC1 2.9357 3.8572 2.6901 6.5841
G-402 GDSC1 3.0414 4.5176 2.4768 7.7563
SW982 GDSC1 3.1886 4.8238 2.4571 7.3189
Rh30 GDSC1 3.2062 5.0107 2.3793 7.8638
VA-ES-BJ GDSC1 3.2727 4.7047 2.5891 5.9603
G-401 GDSC1 3.2731 5.4559 2.214 8.9124
RD GDSC1 3.2975 5.1086 2.4081 7.2952
A-204 GDSC1 3.3129 4.6063 2.6722 5.1565
KYM-1 GDSC1 3.3151 4.442 2.7562 4.4867
Rh18 GDSC1 3.3692 5.9303 2.057 9.7917
STS-0421 GDSC1; GDSC2 3.4655 6.2883 1.9566 8.2311
EW-8 GDSC1 3.4729 4.7176 2.7456 4.0273
MES-SA GDSC1 3.502 6.0414 2.1092 8.9194
RKN GDSC1 3.7183 4.8825 2.8421 2.5665
TE 441.T GDSC2 3.8429 5.7162 2.5263 3.7096
Rh41 GDSC1 4.2031 6.4121 2.435 4.3718
SW684 GDSC1 4.2682 10.0126 0.7287 16.2203
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUM-1 GDSC1 1.5815 3.4129 1.397 22.9666
AGS GDSC1 2.2044 4.2567 1.7628 17.0447
HGC-27 GDSC1 2.2635 5.2968 1.3564 19.7022
SNU-5 GDSC1 2.69 4.0879 2.3373 10.4049
HSC-39 GDSC1 2.8388 4.3577 2.3616 9.5261
23132/87 GDSC1 2.8437 4.3192 2.3846 9.3284
NUGC-3 GDSC1 2.8607 7.9609 0.6077 22.0312
SK-GT-2 GDSC1 2.9279 5.0053 2.1329 10.9058
NCI-N87 GDSC1 3.1702 4.8211 2.4425 7.5053
Fu97 GDSC1 3.2635 4.8305 2.5184 6.5521
GCIY GDSC1 3.2674 5.0458 2.4141 7.3589
MKN45 GDSC1 3.3221 4.4421 2.762 4.4156
ECC12 GDSC2 3.3304 5.502 2.239 6.8314
Hs 746.T GDSC1 3.3504 5.536 2.2385 8.4379
IM95 GDSC1 3.454 4.8237 2.6781 4.6188
MKN1 GDSC1 3.5856 6.4535 1.9701 9.7152
TMK-1 GDSC1; GDSC2 3.7376 7.2559 1.6897 9.1626
RF-48 GDSC1 3.8458 7.0452 1.8768 9.5825
KATO III GDSC1 4.0858 6.1049 2.5039 4.152
TGBC11TKB GDSC1 4.1735 6.8385 2.2127 6.0922
SCH GDSC1; GDSC2 4.2196 7.5565 1.8981 6.7038
ECC10 GDSC1 4.3484 6.3213 2.5668 3.1052
MKN28 GDSC1 4.7839 8.9428 1.6167 8.8254
SNU-16 GDSC1 4.9973 6.4486 2.8384 0.629
MKN7 GDSC1; GDSC2 5.1911 10.6796 1.06 9.493
NUGC-4 GDSC1 5.2185 7.473 2.5329 1.8751
RERF-GC-1B GDSC1 5.3516 8.2013 2.294 3.071
SNU-1 GDSC1 5.608 7.5762 2.6668 0.8402
SNG-M GDSC1 2.161 5.0604 1.3637 20.1441
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 2.3097 3.3487 2.2099 13.3096
CGTH-W-1 GDSC1 2.3234 3.2226 2.2576 12.9096
ASH-3 GDSC1 2.6153 4.3876 2.1266 12.3415
B-CPAP GDSC1 2.6883 3.9009 2.4171 9.8215
K5 GDSC1 2.6999 3.7116 2.5077 9.1008
CAL-62 GDSC1 2.7742 5.0042 1.9899 12.665
BHT-101 GDSC1 2.805 3.8512 2.5593 8.1933
FTC-133 GDSC1 2.8754 6.1058 1.5424 15.6325
8305C GDSC1 3.2239 6.428 1.6865 13.177
WRO GDSC1 3.3031 5.0221 2.4561 6.8962
8505C GDSC1 3.3189 4.8567 2.552 6.0826
TT2609-C02 GDSC1 3.5011 5.3631 2.4466 6.2808
KMH-2 GDSC1; GDSC2 3.7293 5.0986 2.7459 2.6191
ML-1 [Human leukemia] GDSC1; GDSC2 3.7495 5.0148 2.7998 2.2496
HTC-C3 GDSC1 3.8194 6.0957 2.3246 6.2332
TT GDSC1 3.9991 6.9835 2.0202 8.0299
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FaDu GDSC1 1.7461 4.2226 1.2935 22.7614
BB30-HNC GDSC1; GDSC2 1.9796 3.6799 1.7457 14.7323
Ca9-22 GDSC1 2.1648 4.2301 1.7325 17.4661
HSC-4 GDSC1 2.2321 5.0659 1.4323 19.3088
CAL-33 GDSC1 2.3111 5.3294 1.388 19.2508
SAS GDSC1 2.3801 5.1541 1.5379 17.8399
HSC-2 GDSC1 2.447 7.8211 0.3072 25.5297
PCI-04B GDSC1; GDSC2 2.4568 4.7661 1.7944 12.5184
PCI-38 GDSC1 2.5158 4.3418 2.0469 13.413
Detroit 562 GDSC1 2.5203 4.5524 1.9561 14.0716
OSC-19 GDSC1; GDSC2 2.5704 4.3972 2.0771 10.3787
CAL-27 GDSC1 2.5848 4.0492 2.2463 11.5956
PE/CA-PJ15 GDSC1; GDSC2 2.7777 3.9821 2.4738 7.1953
PCI-15A GDSC1; GDSC2 2.8749 4.3368 2.4066 7.2411
SAT [Human HNSCC] GDSC1 2.8787 5.8584 1.6677 14.6813
BB49-HNC GDSC1 2.8962 5.2032 2.0066 12.0163
JHU-022 GDSC1 2.9032 5.1487 2.0397 11.7306
DOK GDSC1 2.9382 4.9217 2.1834 10.4702
BICR 78 GDSC1 2.9571 5.0614 2.1321 10.7898
NCI-H3118 GDSC1 2.9647 5.2363 2.0529 11.3741
SCC-4 GDSC1 2.9796 7.3402 1.0209 18.9086
KON GDSC1; GDSC2 2.9822 5.6974 1.8405 10.4114
PCI-30 GDSC1 3.0555 7.762 0.8761 19.5619
BICR 31 GDSC2 3.1094 4.4169 2.5886 5.3007
HSC-3 GDSC1 3.145 5.1437 2.2597 9.0385
JHU-011 GDSC1; GDSC2 3.1789 6.0105 1.8567 9.695
BICR 10 GDSC1 3.18 4.359 2.6808 5.5948
HO-1-u-1 GDSC1 3.1839 4.8148 2.4576 7.3331
SCC-9 GDSC1 3.196 6.072 1.8406 12.1068
JHU-029 GDSC1; GDSC2 3.2334 5.7619 2.0274 8.4552
KOSC-2 GDSC1; GDSC2 3.2415 5.4523 2.1889 7.4103
HO-1-N-1 GDSC1 3.2529 5.866 1.9919 10.7237
BICR 22 GDSC1 3.3421 4.2881 2.8555 3.6059
OSC-20 GDSC1 3.4139 5.9946 2.0615 9.5977
LB771-HNC GDSC1 3.5663 5.6256 2.3668 6.691
SCC-15 GDSC1 3.5973 7.6247 1.3955 13.9753
UPCI-SCC-090 GDSC1 3.6822 5.7299 2.4034 6.038
SKN-3 GDSC1 3.7812 5.7387 2.4716 5.2139
SCC-25 GDSC1; GDSC2 3.9196 6.2583 2.3171 4.8197
PCI-06A GDSC1; GDSC2 4.0614 5.8102 2.6268 2.6581
BHY GDSC1; GDSC2 4.394 7.088 2.2398 4.2879
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC1 2.0614 3.6628 1.8401 17.2436
UM-UC-3 GDSC1 2.4975 4.4764 1.9678 14.0924
RT-112 GDSC1 2.6931 4.8741 1.975 13.1354
5637 GDSC1 2.7742 5.3814 1.8064 14.0677
639V GDSC1 2.7935 3.7259 2.6006 7.9468
SW780 GDSC1 2.8235 4.02 2.5031 8.5232
T24 GDSC1; GDSC2 3.286 4.5105 2.6974 4.0599
CAL-29 GDSC1 3.2891 5.173 2.3689 7.6351
TCCSUP GDSC1 3.3058 5.2186 2.3601 7.6429
J82 GDSC1 3.3903 4.7703 2.6539 5.0256
SW1710 GDSC1 3.4994 6.0799 2.0879 9.0949
647V GDSC1 3.6537 4.759 2.8575 2.6211
BFTC-905 GDSC1 3.761 6.1298 2.265 6.8685
HT-1376 GDSC1 4.4863 8.9696 1.3998 11.1423
HT-1197 GDSC1 5.3869 14.1837 -0.4989 19.5329
RT-4 GDSC1 5.7083 7.5326 2.7233 0.5699
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC1 1.9795 3.0768 1.9158 17.1916
DSH1 GDSC1 2.1557 5.8568 0.9874 22.76
HEY GDSC1 2.2022 4.2249 1.7738 16.9765
SW954 GDSC1; GDSC2 2.3738 4.9877 1.6094 13.9499
PWR-1E GDSC1 2.5824 3.827 2.3371 10.9415
NT2-D1 GDSC1 2.6412 4.7176 1.999 13.1869
Ca Ski GDSC1 2.6505 4.5521 2.0856 12.4872
SKG-IIIa GDSC1 2.6674 5.3561 1.7185 15.1962
BPH-1 GDSC1 2.742 4.7496 2.0815 12.104
JAR GDSC1; GDSC2 2.8072 4.1555 2.4249 7.3774
DoTc2 4510 GDSC1 2.8893 4.4558 2.3637 9.2845
OVMIU GDSC1 2.8941 4.6306 2.2841 9.878
C-33 A GDSC1 2.9463 4.2923 2.4966 8.0104
SKN GDSC1 2.9984 4.4378 2.4758 7.9447
MS751 GDSC1 3.0241 5.7768 1.8382 12.7931
SW756 GDSC1 3.076 4.3173 2.6069 6.5981
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 3.0901 5.1929 2.1869 7.8899
C-4-I GDSC1 3.1123 4.5514 2.5248 7.0898
NEC8 GDSC1 3.1588 4.7004 2.4924 7.1581
SiSo GDSC1 3.1815 5.6089 2.0595 10.4657
KGN GDSC1 3.3101 5.0815 2.4323 7.0586
CAL-39 GDSC1 3.3676 7.3282 1.3567 15.0761
OVCA433 GDSC1; GDSC2 3.4475 5.9503 2.1108 7.309
TC-YIK GDSC1 3.5142 5.3644 2.4561 6.1624
HT-3 GDSC1 3.5555 5.5304 2.4058 6.421
ACC-OV7 GDSC1; GDSC2 3.6314 5.2736 2.5905 3.8055
HEC-1 GDSC1 3.6556 7.6328 1.4379 13.4679
SiHa GDSC1 3.6869 5.5032 2.5185 5.13
PEO1 GDSC1 3.7186 6.5334 2.0336 8.7893
SW962 GDSC1; GDSC2 3.7267 7.3707 1.6242 9.5962
JEG-3 GDSC1; GDSC2 3.7659 9.0415 0.8232 14.2628
LB831-BLC GDSC1 3.9003 5.5892 2.6265 3.7091
ME-180 GDSC1 3.9072 9.5522 0.6801 17.6935
HeLa GDSC1 3.9308 5.4914 2.6929 3.1405
OVCA420 GDSC1 4.6455 6.7398 2.5492 2.6523
UWB1.289 GDSC1; GDSC2 5.129 9.3837 1.6321 6.4005
JHOS-3 GDSC1; GDSC2 5.4745 8.348 2.2951 2.3128
OV17R GDSC1; GDSC2 5.5208 7.4786 2.6673 0.7276
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018517)
2 Recent advances in Hsp90 inhibitors as antitumor agents. Anticancer Agents Med Chem. 2008 Oct;8(7):761-82.