Details of the Drug

General Information of Drug (ID: DM0AEDT)

Drug Name
Tofersen
Synonyms BIIB067; IONIS-SOD1RX; Tofersen
Indication
Disease Entry ICD 11 Status REF
Amyotrophic lateral sclerosis 8B60.0 Approved [1]
Drug Type
Antisense oligonucleotide
Sequence
CAGGATACATTTCTACAGCU
Cross-matching ID
UNII
2NU6F9601K
DrugBank ID
DB14782
TTD ID
D0I1CQ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SOD1 messenger RNA (SOD1 mRNA) TTP9K3Q SODC_HUMAN Inhibitor [2]
Superoxide dismutase Cu-Zn (SOD Cu-Zn) TT6RVLG SODC_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 215887.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)