Details of the Drug

General Information of Drug (ID: DM0CL4I)

Drug Name
MCS-110
Synonyms Colony stimulating factor-1 inhibiting antibody (cancer), Novartis; Anti-CSF-1 antibody (cancer), Novartis
Indication
Disease Entry ICD 11 Status REF
Bone metastases 2D50 Phase 2 [1]
Tenosynovial giant cell tumour 2F7B Phase 2 [2]
Triple negative breast cancer 2C60-2C65 Phase 2 [2]
Advanced malignancy 2A00-2F9Z Phase 1/2 [2]
Breast cancer 2C60-2C65 Phase 1 [3]
Cross-matching ID
TTD ID
D04EAT
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Colony stimulating factor-1 receptor (CSF-1R) TT731LW E9PEK4_HUMAN Modulator [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01643850) MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCTTS). U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.