Details of the Drug

General Information of Drug (ID: DM0I5LM)

Drug Name
DdRNAi therapy rHIV7-shl-TAR-CCR5RZ, stem cells
Synonyms
BLT-HIV; Lentiviral vector delivered DNA-directed RNAi therapeutic (HIV infection), Benitec; RHIV7-shl-TAR-CCR5RZ; T-cell therapy (HIV infection), Benitec; Lentiviral vector delivered DNA-directed RNAi therapeutic (HIV-associated lymphoma), Benitec; DdRNAi therapy (rHIV7-shl-TAR-CCR5RZ, T-cells, HIV), Benitec; DdRNAi therapy (rHIV7-shl-TAR-CCR5RZ, stem cells, HIV/lymphoma), Benitec
Indication
Disease Entry ICD 11 Status REF
Human immunodeficiency virus infection 1C62 Phase 1/2 [1]
Drug Type
RNAi therapeutics
Cross-matching ID
TTD ID
D0O4RB

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CCR5 messenger RNA (CCR5 mRNA) TTJIH8Q CCR5_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of Benitec Ltd.
2 Progress on RNAi-based molecular medicines. Int J Nanomedicine. 2012; 7: 3971-3980.