Details of the Drug

General Information of Drug (ID: DM0P63W)

• Drug Name: Guanidine Hydrochloride
• Synonyms: Guanidine hydrochloride; 1950/1/1; Guanidinium chloride; Guanidine, monohydrochloride; guanidine HCl; Aminoformamidine hydrochloride; Aminomethanamidine hydrochloride; GUANIDINE MONOHYDROCHLORIDE; Guanidine chloride; Iminourea hydrochloride; Carbamidine hydrochloride; Guanidinium hydrochloride; Guanidine (hydrochloride); UNII-3YQC9ZY4YB; Guanidium chloride; USAF EK-749; Guanidine, hydrochloride (1:1); EINECS 200-002-3; 3YQC9ZY4YB; AI3-19014; MFCD00013026; Guanidine Hydrochloride, ULTROL& Grade; Guanidinehydrochloride

Indication

Disease Entry	ICD 11	Status	REF
Muscle fatigue	FB32.5	Approved	[1]

• Therapeutic Class: Neurology Agents
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 95.53
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 0
  Hydrogen Bond Donor Count; 4
  Hydrogen Bond Acceptor Count; 1
• Chemical Identifiers:
  Formula: CH6ClN3
  IUPAC Name: guanidine;hydrochloride
  Canonical SMILES: C(=N)(N)N.Cl
  InChI: InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
  InChIKey: PJJJBBJSCAKJQF-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 5742
  ChEBI ID: CHEMBL32735
  CAS Number: 50-01-1
  TTD ID: D0F7NZ
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Adrenergic receptor Alpha-2 (ADRA2)	TTQ8AFT	NOUNIPROTAC	Modulator	[2]

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [2] Guanidine-based 2-adrenoceptor ligands: Towards selective antagonist activity.Eur J Med Chem.2014 Jul 23;82:242-54.