Details of the Drug

General Information of Drug (ID: DM10MKG)

Drug Name

F-991

Synonyms

Asthma therapeutic, Fornix; Immunoglobulin light chain antagonist, Fornix; Inflammatory bowel disease therapeutic, Fornix; Multiple sclerosis therapeutic, Fornix

Indication

Disease Entry	ICD 11	Status	REF
Allergic skin disorder	4A82	Discontinued in Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C43H60N14O11S2
Canonical SMILES: CC(C)CC(C(=O)O)NC(=O)C(CS)NC(=O)C(CS)NC(=O)C(CC1=CN=CN1)NC(=O)CNC(=O)C(CO)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CN=CN4)NC(=O)C(C)N
InChI: 1S/C43H60N14O11S2/c1-21(2)8-31(43(67)68)54-41(65)33(17-69)57-42(66)34(18-70)56-39(63)29(10-24-13-45-19-49-24)51-35(59)15-48-37(61)32(16-58)55-38(62)28(9-23-12-47-27-7-5-4-6-26(23)27)53-40(64)30(52-36(60)22(3)44)11-25-14-46-20-50-25/h4-7,12-14,19-22,28-34,47,58,69-70H,8-11,15-18,44H2,1-3H3,(H,45,49)(H,46,50)(H,48,61)(H,51,59)(H,52,60)(H,53,64)(H,54,65)(H,55,62)(H,56,63)(H,57,66)(H,67,68)/t22-,28-,29-,30-,31-,32-,33-,34-/m0/s1
InChIKey: BWCARSGBKSFOCL-OSTURJEUSA-N

Cross-matching ID

PubChem CID: 10290602
CAS Number: 188193-59-1
TTD ID: D02ZLM

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022093)