Details of the Drug

General Information of Drug (ID: DM15ZIB)

Drug Name
Mosunetuzumab
Synonyms RG7828; RO7030816; BTCT4465A
Indication
Disease Entry ICD 11 Status REF
Follicular lymphoma 2A80 Approved [1]
Affected Organisms
Humans and other mammals
Drug Type
Antibody
Cross-matching ID
UNII
LDJ89SS0YG
DrugBank ID
DB15434
TTD ID
D2HDB8

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leukocyte surface antigen Leu-16 (CD20) TTUE541 CD20_HUMAN Inhibitor [2]
T-cell surface glycoprotein CD3 (CD3) TTUN7MC NOUNIPROTAC Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 761263.
2 Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling. NPJ Syst Biol Appl. 2020 Aug 28;6(1):28.