Details of the Drug

General Information of Drug (ID: DM1CZSJ)

Drug Name
(+)-JQ1
Synonyms
1268524-70-4; (+)-JQ-1; JQ1 compound; (+)-JQ1; JQ-1; UNII-1MRH0IMX0W; (S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate; (S)-JQ1; 1MRH0IMX0W; JQ1; CHEMBL1957266; AK109409; (S)-(+)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate; (S)-(+)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate; (S)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3
Indication
Disease Entry ICD 11 Status REF
Testicular cancer 2C80 Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 457
Logarithm of the Partition Coefficient (xlogp) 4.9
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C23H25ClN4O2S
IUPAC Name
tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate
Canonical SMILES
CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
InChI
InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1
InChIKey
DNVXATUJJDPFDM-KRWDZBQOSA-N
Cross-matching ID
PubChem CID
46907787
ChEBI ID
CHEBI:95080
CAS Number
1268524-70-4
UNII
1MRH0IMX0W
DrugBank ID
DB17021
TTD ID
D0ZW4W

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bromodomain and extraterminal domain protein (BET) TTE4BSY NOUNIPROTAC Inhibitor [1]
Bromodomain testis-specific protein (BRDT) TT7CPI5 BRDT_HUMAN Inhibitor [2]
Bromodomain-containing protein 4 (BRD4) TTRA6BO BRD4_HUMAN Inhibitor [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1) OTG2T749 CP24A_HUMAN Gene/Protein Processing [4]
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) OT5I4Y9K PLCB_HUMAN Gene/Protein Processing [5]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (PLCB2) OTPAHDGO PLCB2_HUMAN Gene/Protein Processing [5]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (PLCD1) OT6WFVXZ PLCD1_HUMAN Gene/Protein Processing [4]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (PLCH2) OTYERO80 PLCH2_HUMAN Gene/Protein Processing [6]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) OTGVC9MY PLCG2_HUMAN Gene/Protein Processing [7]
10 kDa heat shock protein, mitochondrial (HSPE1) OT7JSZLB CH10_HUMAN Gene/Protein Processing [8]
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Gene/Protein Processing [4]
15-hydroxyprostaglandin dehydrogenase (HPGD) OTYZI6JB PGDH_HUMAN Gene/Protein Processing [4]
17-beta-hydroxysteroid dehydrogenase type 2 (HSD17B2) OT3K7HY5 DHB2_HUMAN Gene/Protein Processing [7]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Testicular cancer
ICD Disease Classification 2C80
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Bromodomain-containing protein 4 (BRD4) DTT BRD4 3.27E-01 0.02 0.04
Bromodomain testis-specific protein (BRDT) DTT BRDT 2.39E-01 0.02 0.14
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 2.4988 6.7273 0.8926 15.7303
HuO9 GDSC1; GDSC2 -1.4678 2.5722 -1.7213 43.004
SK-N-MC CTRP2 0.16 6.4538 -0.4938 40.7316
EW-13 GDSC1; GDSC2 0.7991 5.0248 -0.0296 26.1595
MHH-ES-1 GDSC1; GDSC2; CTRP2 0.8554 7.1676 0.0392 36.8641
SW1353 CTRP2 1.2677 9.2735 -0.3034 36.1955
NY GDSC1; GDSC2 1.951 8.1469 -0.3105 23.3268
TC71 CTRP2 1.9584 8.6842 0.6638 33.5075
ES7 GDSC1; GDSC2 2.2477 6.7256 0.6588 17.7216
ES4 GDSC1; GDSC2 2.2837 8.5092 -0.1807 21.6938
CAL-78 GDSC1; GDSC2; CTRP2 2.3126 7.2496 1.5889 27.3672
SaOS-2 GDSC1; GDSC2; CTRP2 2.33 7.9883 1.3332 28.1735
SK-PN-DW GDSC1; GDSC2 2.3497 8.0857 0.0882 20.2396
CHSA0108 GDSC1; GDSC2 2.4049 9.4368 -0.5298 22.8582
ES8 GDSC1; GDSC2 2.4435 9.8316 -0.6911 23.4165
EW-16 GDSC1; GDSC2 2.4793 7.9198 0.2878 18.8801
MG-63 GDSC1; GDSC2; CTRP2 2.6255 12.3881 -0.288 33.6168
EW-11 GDSC1; GDSC2 2.9423 9.7267 -0.2021 19.8544
EW-22 GDSC1; GDSC2 3.0499 6.3513 1.575 10.446
A-673 GDSC1; GDSC2; CTRP2 3.0636 6.7943 2.5596 21.6522
EW-3 GDSC1; GDSC2 3.1795 7.7139 1.0061 13.1936
ES5 GDSC1; GDSC2 3.2614 10.3848 -0.2601 19.2423
EW-18 GDSC1; GDSC2 3.2716 7.372 1.2548 11.6092
CHSA0011 GDSC1; GDSC2 3.3149 8.6004 0.6769 14.5662
CADO-ES1 GDSC1; GDSC2 3.4246 7.5376 1.299 10.9761
EW-12 GDSC2 3.511 9.7756 0.2513 18.0977
SK-ES-1 GDSC1; GDSC2; CTRP2 3.6597 10.1999 1.7529 22.9559
NOS-1 [Human HNSCC] GDSC1; GDSC2 3.7586 10.1964 0.2415 15.6172
TC-71 GDSC1; GDSC2 4.2209 8.4298 1.4729 8.1901
SJSA-1 GDSC1; GDSC2; CTRP2 4.4311 14.4097 0.4514 25.2768
U2OS GDSC1; GDSC2; CTRP2 4.4776 15.4005 0.0041 26.4397
ES1 GDSC1; GDSC2 4.5778 8.108 1.8772 5.3417
EW-1 GDSC1; GDSC2 4.5961 8.885 1.5173 7.1987
EW-24 GDSC1; GDSC2 4.8626 6.2033 2.875 0.4152
CHSA8926 GDSC1; GDSC2 4.9702 10.156 1.1618 8.331
HuO-3N1 GDSC1; GDSC2 5.0924 14.1739 -0.7086 16.8107
ES6 GDSC1; GDSC2 5.1768 14.4083 -0.7616 16.8489
EW-7 GDSC1; GDSC2 5.202 10.4097 1.1958 7.7329
CAL-72 GDSC1; GDSC2 5.4566 15.9213 -1.2994 18.3556
U-CH2 GDSC2 5.4772 7.4085 2.6756 0.7287
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 5.4914 11.6675 2.7597 14.8038
Hs 888.T CTRP2 6.2217 11.5892 3.4183 10.6685
H-EMC-SS GDSC1; GDSC2 6.2394 8.8441 2.4507 0.8574
HOS GDSC1; GDSC2; CTRP2 6.7598 18.2967 0.5038 21.2702
Hs 822.T CTRP2 7.2906 16.6891 1.7216 15.2726
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -0.7669 5.57 -1.2649 46.0203
JK1 CTRP2 0.371 5.3381 0.0304 38.7338
JM1 GDSC1; GDSC2; CTRP2 0.4552 4.5808 0.273 40.314
SEM CTRP2 -4.5122 -3.1182 -4.5122 70.3261
KMS-26 CTRP2 -4.1908 -1.8649 -4.1909 68.1118
Kasumi-1 GDSC1; GDSC2; CTRP2 -4.0243 -1.3982 -4.0248 66.9543
SUP-B8 GDSC1; GDSC2 -3.7934 -1.1574 -3.7997 62.5603
OCI-Ly7 GDSC2 -3.7228 -1.8493 -3.7232 70.4223
A3/Kawakami GDSC1; GDSC2; CTRP2 -3.6574 -2.132 -3.6574 64.6326
MV4-11 GDSC1; GDSC2; CTRP2 -3.4241 -2.0417 -3.4241 63.0797
SET-2 CTRP2 -3.4051 1.5734 -3.474 65.8043
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 -3.2628 -2.7306 -3.2628 62.006
HuT 78 CTRP2 -3.2198 1.1033 -3.2549 61.1487
Pfeiffer CTRP2 -3.1686 2.3519 -3.2938 60.2125
MOLT-13 GDSC1; GDSC2; CTRP2 -3.1223 0.541 -3.1469 58.027
KMS-21-BM CTRP2 -3.1197 -0.6359 -3.1204 61.0124
OPM-2 GDSC1; GDSC2; CTRP2 -3.1104 -1.0413 -3.1106 60.9787
KMS-12-BM GDSC1; GDSC2; CTRP2 -3.1082 -0.5673 -3.1091 60.9303
NALM-6 GDSC1; GDSC2; CTRP2 -2.9901 -0.6998 -2.9905 60.168
KMS-34 CTRP2 -2.973 0.5435 -2.9843 59.8637
BC-1 GDSC1; GDSC2 -2.9507 0.4136 -3.0007 55.1342
H9 GDSC1; GDSC2 -2.9319 -1.6221 -2.9319 55.2354
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 -2.927 -0.1854 -2.9289 59.7097
SIG-M5 GDSC1; GDSC2; CTRP2 -2.83 -1.8017 -2.83 59.1222
MOLP-8 GDSC1; GDSC2; CTRP2 -2.7578 0.5395 -2.7662 62.3841
OCI-AML-2 GDSC1; GDSC2; CTRP2 -2.7453 -1.0691 -2.7454 58.5571
HL-60 GDSC1; GDSC2; CTRP2 -2.6407 -0.0991 -2.642 57.8334
SU-DHL-16 GDSC1; GDSC2 -2.6074 -1.3269 -2.6075 52.3703
P30/OHK GDSC1; GDSC2 -2.4444 -0.5971 -2.4462 50.9284
697 GDSC1; GDSC2; CTRP2 -2.2371 -0.6623 -2.2371 55.1722
GA-10 GDSC1; GDSC2; CTRP2 -2.2346 0.3277 -2.2365 55.138
NCI-H929 GDSC1; GDSC2; CTRP2 -2.1721 2.2952 -2.2423 54.5043
Karpas-45 GDSC1; GDSC2 -2.1675 0.0897 -2.1773 48.4976
WIL2 NS GDSC1; GDSC2 -2.1563 0.6018 -2.1879 48.4216
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 -2.0812 -0.0403 -2.0837 47.2629
Ku812 GDSC1; GDSC2; CTRP2 -2.0693 1.6834 -2.0986 53.9536
MOLM-13 GDSC1; GDSC2; CTRP2 -2.0577 0.966 -2.0653 53.9426
ST486 GDSC1; CTRP2 -2.0544 0.5119 -2.0566 57.6225
KE-37 GDSC1; GDSC2; CTRP2 -2.0485 0.3499 -2.0498 53.9074
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 -2.0469 0.5151 -2.0492 53.8924
Ri-1 CTRP2 -1.9283 3.4981 -2.1166 52.829
KMS-11 GDSC1; GDSC2; CTRP2 -1.912 4.245 -2.2218 52.6188
NU-DHL-1 CTRP2 -1.8981 0.7957 -1.9018 52.9009
YT GDSC1; GDSC2 -1.8095 1.7611 -1.9422 45.6062
NB4 GDSC1; GDSC2; CTRP2 -1.7901 -0.3348 -1.7901 48.7821
MOLT-16 GDSC1; GDSC2; CTRP2 -1.7682 0.8078 -1.7712 52.0415
SU-DHL-10 GDSC1; GDSC2; CTRP2 -1.7358 -0.2621 -1.7358 51.8328
MHH-CALL-4 GDSC2; CTRP2 -1.7195 0.9968 -1.7241 51.7164
MOLT-3 CTRP2 -1.6884 2.7046 -1.7703 51.4475
CMK GDSC1; CTRP2 -1.6819 1.7774 -1.705 51.4486
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 -1.6633 1.6075 -1.6959 47.9158
HEL GDSC1; GDSC2; CTRP2 -1.6496 0.4949 -1.6503 51.2572
PF-382 GDSC1; GDSC2; CTRP2 -1.6399 0.9282 -1.6431 51.1899
NCO2 CTRP2 -1.6062 1.5443 -1.62 50.9594
JJN-3 GDSC1; GDSC2; CTRP2 -1.5986 2.0508 -1.6316 50.8991
HAL-01 GDSC1; GDSC2 -1.5552 1.9605 -1.7003 43.4827
EM-2 GDSC1; GDSC2; CTRP2 -1.5444 0.7341 -1.5458 50.5568
A4/Fukuda GDSC1; GDSC2; CTRP2 -1.5347 2.8631 -1.6235 50.4704
SU-DHL-6 GDSC1; GDSC2; CTRP2 -1.5283 1.0385 -1.5318 50.4488
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -1.5248 1.8924 -1.5486 50.4204
P32/ISH GDSC1; GDSC2 -1.5122 2.067 -1.6717 43.1533
M-07e CTRP2 -1.4925 3.7183 -1.6823 50.1948
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 -1.4656 1.6289 -1.493 46.5157
HH [Human lymphoma] GDSC1; GDSC2 -1.452 7.5148 -3.423 45.3091
SU-DHL-5 GDSC1; GDSC2; CTRP1 -1.4284 0.687 -1.4421 42.0085
MEG-01 GDSC1; GDSC2 -1.4269 2.1779 -1.599 42.4624
Kasumi-2 CTRP2 -1.4094 2.0407 -1.4365 49.6643
OCI-M1 GDSC1; GDSC2; CTRP2 -1.4057 0.2462 -1.4058 49.6336
Loucy GDSC1; GDSC2 -1.3868 2.7573 -1.6744 42.4156
EoL-1 GDSC1; GDSC2; CTRP2 -1.3485 1.0133 -1.3507 49.2537
BL-41 GDSC1; GDSC2 -1.3023 1.2585 -1.3456 41.0036
SU-DHL-8 GDSC1; GDSC2; CTRP2 -1.2797 1.6102 -1.2897 48.802
KG-1 GDSC1; GDSC2 -1.2651 2.5612 -1.4987 41.2624
SUP-B15 GDSC1; GDSC2; CTRP2 -1.2464 2.5328 -1.2953 52.0979
SUP-T1 GDSC1; GDSC2; CTRP2 -1.2369 3.9427 -1.4425 48.628
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 -1.2312 2.8143 -1.3006 48.5219
MOTN-1 CTRP2 -1.2282 9.7434 -3.1388 51.2332
CRO-AP2 GDSC1; GDSC2 -1.1666 1.9876 -1.2873 40.0806
KHM-1B CTRP2 -1.1405 2.6822 -1.1956 47.9233
ML-2 GDSC1; GDSC2 -1.1141 1.7563 -1.1989 39.5021
KMOE-2 GDSC1; GDSC2 -1.0944 2.564 -1.314 39.7782
HEL 92.1.7 CTRP2 -1.089 1.0396 -1.0902 47.5256
LC4-1 GDSC1; GDSC2 -1.085 3.1994 -1.4546 40.1438
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 -1.0638 1.1998 -1.0659 47.3594
MM1.S GDSC2; CTRP2 -1.0558 5.8309 -1.647 47.7542
CCRF-CEM GDSC1; GDSC2 -0.9326 3.1923 -1.2865 38.8343
P31/FUJ GDSC1; GDSC2; CTRP2 -0.9316 1.8001 -0.9406 46.4922
F-36P CTRP2 -0.9313 1.9501 -0.9441 46.4967
JSC-1 GDSC1; GDSC2 -0.9299 4.034 -1.5306 44.1389
BV-173 GDSC1; GDSC2; CTRP2 -0.9276 2.86 -0.9869 46.5397
CTB-1 GDSC1; GDSC2 -0.9207 2.4537 -1.1033 38.169
Jiyoye GDSC1; GDSC2 -0.9155 3.1881 -1.2666 38.6828
Peer CTRP2 -0.9153 1.9777 -0.9286 46.3914
GR-ST GDSC1; GDSC2 -0.8556 3.6164 -1.3209 38.5402
NKM-1 GDSC1; GDSC2 -0.8548 2.0559 -0.9634 37.3266
AML-193 CTRP2 -0.8161 1.6211 -0.8207 45.7161
BALL-1 GDSC1; GDSC2 -0.8138 2.3023 -0.9596 37.11
BCP-1 CTRP2 -0.7967 3.4723 -0.9083 45.7619
ALL-SIL GDSC1; GDSC2 -0.7746 2.932 -1.0486 37.2372
KMS-20 CTRP2 -0.7714 6.1647 -1.427 46.1922
KE-97 CTRP2 -0.7349 3.8425 -0.8899 45.4263
BONNA-12 GDSC2 -0.6974 5.3368 -1.742 43.0773
Karpas-422 GDSC1; GDSC2; CTRP2 -0.6722 5.5316 -1.1522 45.4424
RCH-ACV GDSC1; GDSC2; CTRP2 -0.6711 5.0713 -1.0434 45.3102
ARH-77 GDSC1; GDSC2 -0.6583 4.6909 -1.4599 37.956
PL21 CTRP2; CTRP1 -0.6429 4.594 -0.915 45.0077
SK-MM-2 GDSC1; GDSC2; CTRP2 -0.6232 5.9286 -1.2008 45.2625
DND-41 GDSC1; GDSC2; CTRP2 -0.6155 3.8083 -0.7577 44.6407
RPMI-8402 GDSC1; GDSC2; CTRP2 -0.574 3.8523 -0.7194 44.379
P12-Ichikawa GDSC1; CTRP2 -0.5661 2.0461 -0.5752 44.0637
KMS-18 CTRP2 -0.5293 4.6226 -0.7975 44.2921
MHH-PREB-1 GDSC1; GDSC2 -0.4843 3.8188 -0.9775 35.5645
DoHH2 GDSC1; GDSC2; CTRP2 -0.4791 2.1112 -0.4884 43.4854
KMS-27 CTRP2 -0.4783 4.0289 -0.6422 43.7957
OCI-Ly3 CTRP2 -0.4653 2.605 -0.4915 43.4351
CESS GDSC1; GDSC2 -0.4035 4.5735 -1.1431 35.7487
ALL-PO GDSC1; GDSC2 -0.3868 4.4258 -1.0729 35.434
OCI-AML-5 GDSC1; GDSC2; CTRP2 -0.3526 2.5683 -0.3741 42.6759
CTV-1 GDSC1; GDSC2 -0.3425 2.0185 -0.4113 32.6668
AMO1 GDSC1; GDSC2; CTRP2 -0.2874 2.3833 -0.3007 42.2214
PL-21 GDSC1; GDSC2 -0.2362 4.6808 -1.0017 34.4893
LP-1 GDSC1; GDSC2; CTRP2 -0.2348 4.6589 -0.4858 42.4012
MY-M12 GDSC1; GDSC2 -0.1921 2.8768 -0.4013 36.2119
Ki-JK CTRP2 -0.186 3.5269 -0.2686 41.7241
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 -0.1802 3.6515 -0.2758 41.7167
RS4;11 GDSC1; GDSC2; CTRP2 -0.1393 5.6633 -0.604 42.2012
VAL GDSC1; GDSC2 -0.1328 4.5745 -0.8518 33.479
KCL-22 GDSC1; GDSC2; CTRP2 -0.0531 4.2833 -0.2251 41.0648
BC-3 GDSC1; GDSC2 -0.0029 4.0986 -0.5449 35.7519
JURL-MK1 GDSC1; GDSC2; CTRP2 0.0678 2.639 0.0537 39.8607
JeKo-1 GDSC1; GDSC2; CTRP2 0.0682 4.6448 -0.1557 43.0654
MOLM-6 CTRP2 0.0755 5.9407 -0.4416 40.9802
HT GDSC1; GDSC2; CTRP2 0.1301 6.4029 -0.5114 40.8884
Mono-Mac-1 CTRP2 0.1866 9.3832 -1.4921 42.2069
L-428 GDSC1; GDSC2; CTRP2 0.2129 3.5986 0.1444 39.0543
QIMR-WIL GDSC1; GDSC2 0.215 6.7473 -1.3684 33.7483
DB GDSC1; GDSC2; CTRP2 0.2574 5.826 -0.2128 42.2757
L-363 GDSC1; GDSC2; CTRP2 0.3028 5.3133 -0.0381 39.1706
KOPN-8 GDSC1; GDSC2 0.31 5.0611 -0.562 30.4344
Ramos.2G6.4C10 GDSC1; GDSC2 0.3257 4.5815 -0.3614 29.5354
MN-60 GDSC1; GDSC2 0.3455 5.6151 -0.7487 31.0247
LAMA-84 GDSC1; GDSC2; CTRP2 0.3769 3.134 0.3498 37.8436
Daudi GDSC1; GDSC2; CTRP2 0.3827 4.2302 0.2498 40.6915
CML-T1 GDSC1; GDSC2; CTRP2 0.3958 6.2154 -0.1676 39.1006
JVM-3 GDSC1; GDSC2; CTRP2 0.3972 5.062 0.1192 38.4082
Jurkat GDSC1; GDSC2; CTRP2 0.4275 6.5741 -0.2379 39.1308
SUP-M2 GDSC1; GDSC2; CTRP2 0.4652 2.9063 0.4506 37.2166
CA46 GDSC1; GDSC2; CTRP2 0.4751 6.0569 -0.037 38.4883
Karpas-1106P GDSC1; GDSC2 0.5381 5.7859 -0.6193 29.7296
Raji GDSC1; GDSC2; CTRP2 0.5624 7.405 -0.6464 35.7021
RL GDSC1; GDSC2; CTRP2 0.644 3.4779 0.6054 38.5792
SUP-HD1 GDSC1; GDSC2; CTRP2 0.684 4.8487 0.4722 36.3594
Namalwa GDSC1; GDSC2; CTRP2 0.7224 6.4821 0.1111 37.1824
OCI-Ly19 GDSC1; GDSC2; CTRP2 0.7367 6.6327 0.0812 37.2025
Farage GDSC1; GDSC2 0.7425 6.2758 -0.6205 28.9258
KO52 CTRP2 0.7451 11.5808 -1.8218 40.6629
SR GDSC1; GDSC2; CTRP2 0.7664 6.1902 0.2439 36.6792
DG-75 GDSC1; GDSC2 0.7917 4.7822 0.0595 25.7791
DEL GDSC1; GDSC2; CTRP2 0.7984 5.6245 0.4283 36.0638
HC-1 GDSC1; GDSC2 0.8307 6.287 -0.5353 28.2379
TF-1 CTRP2 0.8352 6.1147 0.3401 36.17
L-540 GDSC1; GDSC2; CTRP2 0.842 4.1875 0.7452 34.9703
SUP-T11 CTRP2 0.8497 4.7474 0.6694 35.1771
WSU-NHL GDSC1 0.8739 5.0625 -0.9128 16.6696
HPB-ALL CTRP2 0.8846 4.6946 0.7161 34.911
RPMI-6666 GDSC1; GDSC2; CTRP2 0.8885 8.5808 -0.433 37.8072
VL51 GDSC1; GDSC2 0.926 6.7489 -0.6461 28.3266
MLMA GDSC1; GDSC2 0.9516 7.0536 -0.7596 28.6809
ROS-50 GDSC1; GDSC2 0.9613 6.5804 -0.5342 27.7376
SCC-3 GDSC1; GDSC2 1.0186 3.7963 0.6643 24.9844
ME1 CTRP2 1.0348 5.9249 0.6094 34.6942
OCI-Ly10 CTRP2 1.0758 7.2611 0.2469 35.5429
KYO-1 CTRP2 1.1641 6.6258 0.549 34.4096
KMS-28BM CTRP2 1.2645 7.5661 0.3455 34.6178
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 1.3008 5.7847 0.9361 32.7832
BL-70 CTRP2 1.3305 4.199 1.2617 31.6336
Sc-1 GDSC1 1.3582 7.2246 -1.5764 18.9244
EB1 CTRP2 1.3871 8.0266 0.31 34.2895
Karpas-299 GDSC1; GDSC2; CTRP2 1.4018 6.1897 0.9373 32.4352
RPMI-8866 GDSC1; GDSC2 1.4352 3.7063 1.1465 18.0271
Hs 611.T CTRP2 1.4592 6.8978 0.7839 32.707
NK-92MI GDSC1; GDSC2 1.5706 3.423 1.3821 18.5717
SU-DHL-1 GDSC1; GDSC2; CTRP2 1.5849 7.2472 0.8031 32.2269
ME1 GDSC1; GDSC2 1.5934 8.3781 -0.7597 26.3986
Mono-Mac-6 GDSC1; GDSC2; CTRP2 1.6589 11.1878 -0.712 35.7888
U-937 CTRP2; CTRP1 1.7311 6.4201 1.2295 30.4104
Reh GDSC1; GDSC2; CTRP2 1.7426 6.647 0.9046 26.7062
MHH-CALL-2 GDSC1 1.8333 3.6262 -0.6076 1.0251
IM-9 GDSC1; GDSC2 1.8705 7.8016 -0.2185 23.1791
MOLT-4 GDSC1; GDSC2 1.8949 6.6693 0.3488 20.4207
EHEB GDSC1; CTRP2 2.1017 9.2112 0.5985 31.1569
KM-H2 GDSC1; GDSC2; CTRP2 2.146 7.9032 1.1693 29.277
L-1236 GDSC1; GDSC2; CTRP2 2.1545 9.2172 0.6512 30.8398
RC-K8 GDSC1 2.2308 7.0552 -0.8014 11.8337
HuNS1 CTRP2 2.4889 8.6356 1.2429 27.9884
KY821 GDSC1; GDSC2 2.6134 3.6264 2.4484 7.0517
EJM GDSC1; GDSC2; CTRP2; CTRP1 2.6252 8.1821 1.5705 26.4849
MHH-CALL-3 CTRP2 2.73 12.403 -0.192 31.4113
U-698-M GDSC1; GDSC2 2.8024 6.2639 1.3983 12.1131
TUR GDSC1; GDSC2 2.8629 11.082 -0.9469 23.2273
K-562 GDSC1; GDSC2; CTRP2 2.9576 7.673 2.124 23.5544
EB2 GDSC1; GDSC2 2.9831 9.7423 -0.1748 19.6165
Granta-519 GDSC1; GDSC2; CTRP2 3.0321 7.0279 2.4442 22.168
HD-MY-Z CTRP2 3.1747 6.7722 2.6875 20.8552
U266B1 GDSC1; GDSC2; CTRP2 3.3567 10.6899 1.2252 25.5736
HDLM-2 GDSC1; GDSC2; CTRP2 3.3638 9.4722 1.7882 23.6227
TK [Human B-cell lymphoma] GDSC1; GDSC2 3.6622 9.287 0.618 13.9832
ATN-1 GDSC1; GDSC2 3.8698 8.6338 1.1077 10.9265
JVM-2 GDSC1; GDSC2; CTRP2 3.8956 13.4433 0.4306 26.6373
BE-13 GDSC1; GDSC2 4.3153 9.7553 0.8909 11.0575
MOLP-2 CTRP2 4.4531 12.3691 1.4745 21.946
Hs 445 GDSC1; GDSC2 4.8554 11.5964 0.3827 12.4406
Karpas-231 GDSC1; GDSC2 4.9826 6.4835 2.819 0.5086
P3HR-1 CTRP2 5.3591 12.5626 2.198 17.2663
REC-1 CTRP2 5.8535 7.1664 5.3173 3.4459
Ci-1 CTRP2 5.9187 6.4876 5.711 1.7879
Karpas-620 GDSC1; GDSC2; CTRP2 6.1121 7.2606 5.4918 2.1955
MJ CTRP2 7.0825 18.1113 0.8527 19.6135
MC116 GDSC1; GDSC2; CTRP2 7.2867 8.0883 5.7855 0.0794
⏷ Show the Full List of 219 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 0.8219 17.0489 -4.2456 44.4563
TE8 CTRP2 2.7096 11.7531 0.0906 30.7439
TE-11 GDSC1; GDSC2; CTRP2 0.0951 3.0385 0.0639 39.7291
KYSE-270 GDSC1; GDSC2 1.2954 9.5769 -1.6214 30.5001
TE-15 GDSC1; GDSC2 1.3126 10.4302 -2.0197 31.6488
OE21 GDSC1; GDSC2; CTRP2 1.3817 8.4823 0.1312 34.771
TE-14 CTRP2 1.732 8.7006 0.4177 32.8461
TE-4 GDSC1; GDSC2; CTRP2 2.1146 6.3419 1.6709 27.7038
TE-6 GDSC1; GDSC2; CTRP2 2.2696 8.4042 1.1052 29.0987
TE-10 GDSC1; GDSC2; CTRP2 2.2817 9.0314 0.8618 29.82
TE-5 GDSC1; GDSC2; CTRP2 3.1782 10.4166 1.1732 26.2312
T.T GDSC1; GDSC2 3.6374 14.5275 -2.0201 24.9768
KYSE-410 GDSC1; GDSC2; CTRP2 3.6812 10.9307 1.4321 24.0181
TE-8 GDSC1; GDSC2 3.7457 8.7373 0.9588 12.0099
KYSE-140 GDSC1; GDSC2; CTRP2 3.8005 12.4431 0.8254 25.6892
KYSE-70 GDSC1; GDSC2; CTRP2 4.1909 11.0525 1.8669 21.1921
KYSE-30 CTRP2 5.1805 10.0002 3.3073 13.2654
KYSE-520 GDSC1; GDSC2; CTRP2 6.1935 15.8168 1.2819 18.8308
KYSE-150 GDSC1; GDSC2; CTRP2 6.2046 9.4665 4.4649 6.336
KYSE-510 GDSC1; GDSC2; CTRP2 6.3596 7.6591 5.4823 1.8194
EC-GI-10 GDSC1; GDSC2; CTRP2 6.9377 10.8087 4.3595 5.5318
COLO 680N GDSC1; GDSC2; CTRP2 8.1468 17.5462 1.9376 13.0862
TE-9 GDSC1; GDSC2; CTRP2 8.1729 16.046 2.6872 10.2952
KYSE-180 GDSC1; GDSC2; CTRP2 8.1891 18.7314 1.3874 14.9214
OE33 GDSC1; GDSC2; CTRP2 8.1911 14.5019 3.4432 7.3699
OE19 GDSC1; GDSC2; CTRP2 8.5321 23.7109 -0.811 20.8385
TE-1 GDSC1; GDSC2; CTRP2 9.8591 20.6631 1.6175 11.6999
KYSE-450 GDSC1; GDSC2; CTRP2 12.1535 22.2696 2.2797 6.9067
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 10.1842 20.2338 2.0316 9.8909
Panc 08.13 GDSC1; GDSC2; CTRP2 -0.429 2.6778 -0.4578 43.2007
MIA PaCa-2 GDSC1; GDSC2; CTRP2 -0.3453 2.9187 -0.385 42.6723
MZ-PC-1 GDSC1; GDSC2 0.7308 5.7136 -0.3882 28.0095
HuP-T4 GDSC1; GDSC2; CTRP2 0.8278 6.1197 0.3306 36.2228
KP-1N GDSC1; GDSC2 0.9976 6.332 -0.3856 26.976
BxPC-3 GDSC1; GDSC2; CTRP2 1.082 9.098 -0.4292 37.1115
HuP-T3 GDSC1; GDSC2; CTRP2 2.8446 10.8624 0.6351 28.8379
PANC-1 CTRP2 3.0158 7.2687 2.3394 22.5996
Hs 766T GDSC1; GDSC2; CTRP2 3.3272 10.828 1.132 25.9581
SNU-213 CTRP2 3.3764 10.2131 1.4648 24.7161
TCC-Pan2 CTRP2 3.4773 9.178 2.035 22.4239
CFPAC-1 GDSC1; GDSC2; CTRP2 3.7683 8.7114 2.5389 19.7593
KP-3 GDSC1; GDSC2; CTRP2 3.8446 12.3566 0.909 25.3151
SU.86.86 GDSC1; GDSC2; CTRP2 4.0455 7.7339 3.2481 16.2807
PL4 GDSC1; GDSC2 4.1106 8.8762 1.1716 10.0383
Panc 10.05 GDSC1; GDSC2; CTRP2 4.1973 11.4524 1.6804 21.8454
Capan-1 GDSC1; GDSC2; CTRP2 4.369 10.8583 2.1301 19.7861
HPAC GDSC1; GDSC2; CTRP2 4.4094 10.43 2.3748 18.7624
PK-45H CTRP2 4.4924 11.8888 1.7458 20.8976
Panc 02.03 GDSC1; GDSC2; CTRP2 4.4988 14.1784 0.627 25.9389
KP-4 GDSC1; GDSC2; CTRP2 4.8558 10.5141 2.7554 16.2241
QGP-1 GDSC1; GDSC2; CTRP2 4.8976 14.1477 1.0014 22.4971
PaTu 8988s CTRP2 5.1482 12.6807 1.9526 18.6417
SNU-410 CTRP2 5.498 6.8321 5.1367 5.02
Panc 05.04 CTRP2 5.6226 13.8431 1.7882 18.2216
DAN-G GDSC1; GDSC2; CTRP2 5.8941 12.4237 2.7286 14.0972
SUIT-2 GDSC1; GDSC2; CTRP2 5.9149 14.4008 1.7578 17.7292
PSN1 GDSC1; GDSC2; CTRP2 5.9985 8.5856 4.7354 5.9759
SW1990 GDSC1; GDSC2; CTRP2 6.1017 13.3683 2.4301 15.7899
Capan-2 GDSC1; CTRP2 6.2401 14.1649 2.1461 15.6602
PaTu 8988t GDSC1; GDSC2; CTRP2 7.0227 15.6237 2.0436 15.4597
PK-59 CTRP2 7.119 14.6064 2.6227 12.2361
AsPC-1 GDSC1; GDSC2; CTRP2 7.1882 14.7114 2.6233 12.878
KP-2 GDSC1; GDSC2; CTRP2 7.2455 16.1024 1.978 15.2892
L3.3 CTRP2 7.7056 16.296 2.2285 12.7403
YAPC GDSC1; GDSC2; CTRP2 7.8297 15.3511 2.782 10.4591
Panc 03.27 GDSC1; GDSC2; CTRP2 8.0374 16.1657 2.5332 11.7641
Panc 04.03 GDSC1; GDSC2; CTRP2 8.2031 18.342 1.5887 14.2157
PaTu 8902 GDSC1; GDSC2; CTRP2 8.3167 15.7072 2.9505 9.0868
HPAF-II GDSC1; CTRP2 9.4206 20.4602 1.4192 12.9593
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 4.2431 11.2634 1.8151 22.6885
M14 GDSC1 -1.6492 -0.4107 -1.6546 32.1505
CHL-1 GDSC1; GDSC2 -0.5532 5.7659 -1.757 38.2565
MZ-MEL-7 GDSC1; GDSC2 -0.4744 2.0247 -0.5524 33.8679
Malme-3M CTRP2 -0.3448 11.1819 -2.7832 45.4463
LOX-IMVI GDSC1; GDSC2; CTRP2 0.2877 2.8982 0.2692 38.4106
IST-MEL1 GDSC1; GDSC2 0.3313 8.8317 -2.1988 35.6306
Hs 940.T GDSC1; GDSC2; CTRP2 0.3454 5.9764 -0.1566 39.2761
IGR-1 GDSC1; GDSC2; CTRP2 0.4914 7.336 -0.4119 39.2475
WM35 GDSC1; GDSC2 0.6972 6.8508 -0.9231 30.2751
SH-4 GDSC1; GDSC2 0.7857 6.5296 -0.6892 29.0334
G-361 GDSC1; GDSC2; CTRP2 1.1008 5.9852 0.6654 34.2973
DJM-1 GDSC1; GDSC2 1.1599 7.4793 -0.7507 30.9907
IPC-298 GDSC1; GDSC2; CTRP2 1.2722 8.6226 -0.0399 35.5688
SK-MEL-2 GDSC1; GDSC2 1.491 5.2255 0.6082 20.5146
A-431 GDSC1; GDSC2 1.6 7.8437 -0.4963 25.2947
CP50-MEL-B GDSC1; GDSC2 2.0216 6.4358 0.5824 18.8349
A2058 GDSC1; GDSC2; CTRP2 2.1783 8.0876 1.133 31.3226
WM983B CTRP2 2.1816 9.8113 0.4269 33.3895
Hs 852.T CTRP2 2.1936 9.0984 0.7417 30.4526
WM1552C GDSC1; GDSC2 2.2891 7.4465 0.3463 19.1719
Hs 944.T CTRP2 2.7525 9.2733 1.249 27.1892
COLO 792 GDSC1; GDSC2; CTRP2 2.7846 9.2559 1.2897 28.669
VMRC-MELG GDSC1; GDSC2 2.831 9.6857 -0.2778 20.5099
WM278 GDSC1; GDSC2 2.8743 10.0598 -0.427 21.045
G-mel GDSC1; GDSC2 2.9437 5.6786 1.8153 9.4149
451Lu GDSC1; GDSC2 3.0046 10.8367 -0.703 21.8504
SK-MEL-30 GDSC1; GDSC2; CTRP2 3.0773 10.7818 0.9049 27.3657
HMV-II GDSC1; GDSC2 3.0977 10.6223 -0.5167 20.8109
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 3.2679 8.2771 2.2083 22.3628
WM115 GDSC1; GDSC2; CTRP2 3.3056 7.3372 2.6244 20.7096
A-388 GDSC1; GDSC2 3.4297 10.2453 -0.0504 17.8394
COLO 783 GDSC1; GDSC2 3.443 9.6068 0.2798 16.2294
GAK GDSC1; GDSC2 3.5176 9.4463 0.4212 15.3397
RPMI-7951 GDSC1; GDSC2; CTRP2 3.633 9.7688 1.9252 22.4073
Mel Ho GDSC1; GDSC2; CTRP2 3.7123 10.1622 1.8225 22.5694
MZ-MEL-2 GDSC1; GDSC2 3.7307 11.1374 -0.2506 17.9836
Hs 938.T GDSC1; GDSC2 3.7315 10.3963 0.12 16.2685
HMCB CTRP2 3.8086 8.005 2.8869 19.6616
SK-MEL-24 GDSC1; GDSC2; CTRP2 3.961 11.5257 1.4198 23.342
SK-MEL-31 GDSC1; GDSC2; CTRP2 4.2881 13.2776 0.877 24.3186
COLO 679 GDSC1; GDSC2 4.304 14.4474 -1.4451 21.4131
CP66-MEL GDSC1; GDSC2 4.3085 11.8195 -0.1353 16.0712
LB2518-MEL GDSC1; GDSC2 4.4381 10.3856 0.6716 11.9068
SK-MEL-3 GDSC1; GDSC2; CTRP2 4.4562 9.4035 2.9092 17.6804
Hs 936.T CTRP2 4.51 10.9705 2.2093 19.1494
Hs 294T CTRP2 4.9256 13.5682 1.3138 22.7451
IGR-37 GDSC1; GDSC2; CTRP2 4.9374 12.6229 1.7925 19.6968
COLO 741 CTRP2 4.964 14.3898 0.9404 22.5443
A-375 GDSC1; GDSC2; CTRP2; CTRP1 5.0639 12.3631 2.0349 18.5247
MeWo GDSC1; GDSC2; CTRP2 5.2479 12.0058 2.3764 16.8266
K029AX CTRP2 5.2864 16.3102 0.2669 23.8921
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 5.3092 10.7476 3.0551 14.0084
LB373-MEL-D GDSC1; GDSC2 5.492 14.1556 -0.4102 14.7391
RVH-421 GDSC1; GDSC2; CTRP2 5.5191 11.2358 2.9989 14.7031
WT2-iPS GDSC1; GDSC2; CTRP2 5.6442 8.7058 4.367 8.4033
Hs 934.T CTRP2 5.7051 6.3064 5.5801 2.724
CJM [Human melanoma] CTRP2 5.7174 11.2817 3.1485 13.686
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 5.7775 6.1471 5.7198 1.9866
MMAc-SF GDSC1; GDSC2 5.7878 7.7144 2.6882 0.4518
COLO 800 GDSC1; GDSC2; CTRP2 5.8459 13.9373 1.9314 17.2397
MDA-MB-435S CTRP2 5.8638 13.9225 1.9538 17.121
WM793 GDSC1; GDSC2; CTRP2 6.2243 14.853 1.7891 17.0013
WM88 CTRP2 6.3991 14.2921 2.2123 16.1083
Hs 688(A).T CTRP2 6.4613 10.9736 3.918 8.1576
WM266-4 CTRP2 6.6654 13.3177 2.9114 11.9031
Mel JuSo GDSC1; GDSC2; CTRP2 6.9612 11.8619 3.8599 7.5453
UACC-257 GDSC1; GDSC2; CTRP2 7.127 14.3763 2.7427 11.757
HT-144 GDSC1; GDSC2; CTRP2 7.5661 21.3218 -0.3662 22.2461
IGR-39 CTRP2 7.6202 19.7705 0.4463 19.8816
WM1799 CTRP2 7.8713 15.4761 2.7508 10.5138
Hs 895.T CTRP2 8.0275 19.7772 0.7525 17.2426
UACC-62 GDSC1; GDSC2; CTRP2 8.3114 18.4638 1.6077 13.9793
COLO 829 GDSC1; GDSC2; CTRP2 8.8633 21.4222 0.5594 16.5043
Hs 839.T CTRP2 9.9043 26.5699 -1.2064 20.6113
A101D GDSC1; GDSC2; CTRP2 10.2084 25.6218 -0.5287 18.3721
EquiPSC Line K2 GDSC1; GDSC2 2.6306 8.5331 0.12 19.2457
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC1; GDSC2 0.6665 6.8313 -0.9454 30.4772
ESO-51 GDSC1; GDSC2 2.6092 6.9889 0.8652 15.5447
OACP4 C GDSC1; GDSC2 3.0807 9.5793 -0.01 18.5849
TE-12 GDSC1; GDSC2 3.4936 9.974 0.1379 16.7855
ESO-26 GDSC1; GDSC2 3.5423 6.9065 1.7099 8.4279
KYSE-50 GDSC1; GDSC2 4.3084 12.2012 -0.3247 16.9185
OACM5.1 C GDSC1; GDSC2 4.5072 8.7869 1.5031 7.4468
SK-GT-4 GDSC1; GDSC2 4.9052 12.6734 -0.1089 14.6279
FLO-1 GDSC1; GDSC2 5.1687 12.9285 -0.0428 13.7795
KYAE-1 GDSC1; GDSC2 5.1737 6.8563 2.7578 0.5772
HCE-4 GDSC1; GDSC2 5.3316 12.4626 0.2987 11.8792
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 3.141 12.7744 0.0337 31.2886
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC1; GDSC2 -2.5619 -0.1595 -2.5719 58.8309
CHP-212 GDSC1; GDSC2; CTRP2 -2.1286 1.8918 -2.1701 54.3017
NB(TU)1 GDSC1; GDSC2 -1.837 0.8448 -1.8721 45.6528
IMR-5 GDSC1; GDSC2 -1.4043 2.517 -1.6405 42.4351
SK-N-MC-IXC GDSC1; GDSC2 -1.1443 0.3747 -1.1465 39.4571
KP-N-YS GDSC1; GDSC2 -0.9538 2.8975 -1.2356 43.703
IMR-32 CTRP2 -0.9054 3.334 -1.0078 46.4506
KP-N-SI9s CTRP2 -0.4849 4.5594 -0.7377 43.9885
CHP-126 GDSC1; GDSC2; CTRP2 0.1475 5.9149 -0.3561 40.5091
SK-N-BE(2) CTRP2 0.2605 7.0949 -0.583 40.4923
TGW GDSC1; GDSC2 0.4348 3.6039 0.0898 27.0781
SK-N-BE(2)-M17 GDSC1; GDSC2 0.5325 4.9665 -0.2884 28.3708
SJNB-7 GDSC1; GDSC2 0.6051 7.3892 -1.2601 31.8286
SJNB-17 GDSC1; GDSC2 0.7248 4.9934 -0.0954 30.1724
GOTO GDSC1; GDSC2 1.0586 5.5967 0.0012 25.026
SJNB-14 GDSC1; GDSC2 1.1037 6.1278 -0.1864 25.7098
SJNB-6 GDSC1; GDSC2 1.2274 5.6274 0.1616 23.6498
NH-12 GDSC1; GDSC2 1.2281 4.3089 0.7079 20.9856
SJNB-10 GDSC1; GDSC2 1.9569 6.9714 0.264 20.6329
Kelly GDSC1; GDSC2; CTRP2 2.1724 7.3073 1.4171 28.3821
SK-N-FI GDSC1; GDSC2; CTRP2 2.8843 7.7355 2.0217 24.137
SK-N-DZ GDSC1; GDSC2; CTRP2 3.0205 8.0903 2.0252 23.7307
KP-N-RT-BM-1 GDSC2 3.2784 6.3938 1.7496 10.0695
GI-ME-N GDSC1; GDSC2 3.2859 15.0563 -2.5754 27.5248
LA-N-6 GDSC1; GDSC2 3.3032 8.314 0.8103 13.9032
SJNB-12 GDSC1; GDSC2 3.5429 11.1284 -0.3988 19.1175
SK-N-AS GDSC1; GDSC2; CTRP2 3.5451 11.8459 0.8664 26.2221
SJNB-13 GDSC1; GDSC2 3.7016 7.4466 1.5669 8.8352
SiMa GDSC1; GDSC2; CTRP2 3.7956 12.2578 0.91 25.4369
NB1 GDSC1; GDSC2; CTRP2 4.0418 8.9759 2.6972 18.4357
MHH-NB-11 GDSC1; GDSC2; CTRP2 4.3342 11.0839 1.9882 20.3976
SJNB-5 GDSC1; GDSC2 4.5666 11.1689 0.3813 13.0624
NH-6 CTRP2 5.1699 10.4375 3.0823 14.2042
SK-N-SH GDSC1; GDSC2; CTRP2 5.7938 14.1778 1.767 19.0172
KP-N-YN GDSC1; GDSC2; CTRP2 6.4621 8.449 5.17 3.1461
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -3.9239 0.1616 -3.9413 65.6716
HuH-28 CTRP2 0.9857 8.1151 -0.1536 36.8445
SNU-478 CTRP2 2.6329 10.3282 0.6628 29.3658
SNU-869 CTRP2 5.1509 15.6732 0.4665 24.9372
SNU-1196 CTRP2 5.48 12.212 2.4785 15.933
SNU-308 CTRP2 5.8062 12.8385 2.4469 15.3776
HuCC-T1 GDSC1; GDSC2; CTRP2 6.9254 16.4397 1.5614 16.4846
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC1; GDSC2 -2.1108 1.3995 -2.214 48.0976
Evsa-T GDSC1; GDSC2 -1.0551 0.738 -1.0627 38.6918
MDA-MB-453 GDSC1; GDSC2; CTRP2 -0.6245 1.5469 -0.6268 44.4356
DU4475 GDSC1; GDSC2; CTRP2 -0.552 2.8034 -0.5921 44.0396
CAL-148 GDSC1; GDSC2; CTRP2 -0.0897 2.1632 -0.0949 40.8825
MCF-7 GDSC1; GDSC2; CTRP2; CTRP1 0.8608 7.3333 -0.0105 36.9638
HMC-1-8 CTRP2 1.0434 5.4357 0.74 34.2775
HCC1599 GDSC1; GDSC2 1.2108 6.5138 -0.2529 28.6214
CAL-85-1 GDSC1; GDSC2; CTRP2 1.5363 8.0423 0.4641 35.4344
HCC1569 GDSC1; GDSC2 1.7787 8.0432 -0.4222 24.3784
MDA-MB-361 GDSC1; GDSC2; CTRP2 1.8062 8.8924 0.4191 32.6008
HCC1806 GDSC1; GDSC2; CTRP2 2.0365 6.8379 1.4307 28.7643
HCC38 GDSC1; GDSC2; CTRP2 2.081 8.9162 0.6988 30.9298
HCC1428 GDSC1; GDSC2; CTRP2 2.0847 8.5409 0.8549 30.452
HCC1187 GDSC1; GDSC2 2.3044 6.9314 0.6121 17.7845
SK-BR-3 CTRP2 2.35 7.8819 1.3954 27.9056
COLO 824 GDSC1; GDSC2 2.4574 10.0882 -0.8062 23.8424
OCUB-M GDSC1; GDSC2 2.513 7.8432 0.3562 18.4409
Hs 578T GDSC1; GDSC2; CTRP2 2.5586 9.4776 0.9606 28.681
MRK-nu-1 GDSC1; GDSC2 3.6924 7.6223 1.4722 9.3755
EFM-192A GDSC1; GDSC2; CTRP2 3.8929 10.4436 1.8685 23.3374
BT-474 GDSC1; GDSC2; CTRP2 4.0795 9.4892 0.8446 10.9421
CAMA-1 GDSC1; GDSC2; CTRP2 4.3744 12.8699 1.1564 23.2091
MFM-223 GDSC1; GDSC2 4.3855 7.4629 2.0567 4.7468
MDA-MB-231 GDSC1; GDSC2; CTRP2 4.4285 14.8218 0.2457 25.8795
BT-483 GDSC1; GDSC2 4.453 12.0624 -0.1452 15.785
MDA-MB-175-VII GDSC1; GDSC2 4.5801 12.0654 -0.0506 15.0697
HCC2218 GDSC1; GDSC2; CTRP2 4.6034 10.3732 2.5868 17.4774
HCC70 GDSC1; GDSC2 4.6189 9.3338 1.3162 8.2095
HCC1500 GDSC1; GDSC2; CTRP2 4.7129 12.1559 1.8186 20.1169
AU565 GDSC1; GDSC2; CTRP2 4.7605 9.7735 3.0255 15.3694
YMB-1-E GDSC2 4.804 11.5727 0.357 14.1345
MDA-MB-415 GDSC1; GDSC2 4.8255 13.736 -0.6914 17.3151
MDA-MB-468 GDSC1; GDSC2; CTRP2 4.9519 10.5213 2.8409 15.6642
CAL-51 GDSC1; GDSC2; CTRP2 4.9883 10.1384 3.0622 14.694
MDA-MB-330 GDSC1; GDSC2 5.067 12.4464 0.1196 13.2449
UACC-893 GDSC1; GDSC2 5.103 10.4695 1.1014 8.3898
CAL-120 GDSC1; GDSC2; CTRP2 5.5607 7.8434 4.7157 6.5945
UACC-812 GDSC1; GDSC2 5.7136 7.3414 2.7939 0.2888
HCC1143 GDSC1; GDSC2; CTRP2 5.7448 12.7148 2.4564 15.4665
MDA-MB-157 GDSC1; GDSC2 5.9419 14.8593 -0.4362 13.9755
HCC202 GDSC1; CTRP2 5.9858 14.8501 1.5927 18.173
HCC1395 GDSC1; GDSC2; CTRP2 6.0175 13.6121 2.2381 15.7515
EFM-19 GDSC1; GDSC2 6.0705 15.1251 -0.4758 13.9002
BT-20 GDSC1; GDSC2; CTRP2 6.2007 11.1493 3.6209 9.8712
HCC1954 GDSC1; GDSC2; CTRP2 6.2834 12.5172 3.005 12.2345
HCC1419 GDSC1; GDSC2; CTRP2 6.4458 11.4624 3.6622 9.873
JIMT-1 GDSC1; GDSC2; CTRP2 6.7698 13.2636 3.0201 11.2838
MDA-MB-436 GDSC1; GDSC2 6.8759 18.2279 -1.4175 16.0886
KPL-1 CTRP2 7.2117 8.1527 5.7337 0.181
BT-549 GDSC1; GDSC2; CTRP2 7.3554 19.278 0.4859 19.2106
T-47D GDSC1; GDSC2; CTRP2 8.1355 21.0356 0.2122 18.6941
ZR-75-30 GDSC1; GDSC2; CTRP2 8.3132 16.4251 2.6016 11.0508
HDQ-P1 GDSC1; GDSC2; CTRP2 8.6353 17.0027 2.5452 10.1474
HCC1937 GDSC1; GDSC2; CTRP2 9.035 20.5843 1.0909 14.5871
Hs 578Bst CTRP2 9.0958 34.0538 -5.5057 28.9266
BT 428 CTRP2 0.8302 6.6701 0.1716 36.6286
BT 231 CTRP2 2.0206 10.0436 0.1603 32.6127
BT 416 CTRP2 2.386 6.937 1.7768 26.4931
BT 239 CTRP2 2.7895 13.5411 -0.6712 32.385
BT 271 CTRP2 3.6959 9.64 2.0471 21.7962
BT 139 CTRP2 4.226 12.0271 1.4292 22.651
BT 248 CTRP2 4.3075 11.7243 1.6529 21.6732
BT 245 CTRP2 4.9313 9.7637 3.1916 14.3017
BT 444 CTRP2 5.0047 10.3898 2.9543 15.0908
BT 286 CTRP2 5.1445 9.5396 3.4999 12.5575
BT 359 CTRP2 5.2418 12.3708 2.1897 17.5518
BT 131 CTRP2 5.322 6.5901 5.0609 5.78
BT 145 CTRP2 5.3275 10.3786 3.2542 13.1588
BT 440 CTRP2 5.4368 14.9143 1.0934 21.0124
BT 216 CTRP2 5.6186 6.7191 5.3091 4.0243
BT147 CTRP2 5.6466 11.8212 2.8181 14.2462
BT 228 CTRP2 5.8262 12.3548 2.7056 14.3252
BT 498 CTRP2 5.9522 6.972 5.5017 2.4654
BT 330 CTRP2 6.1496 8.2906 5.0077 4.1585
BT 340 CTRP2 6.3443 7.4894 5.554 1.5495
BT 112 CTRP2 6.4444 13.0853 2.8515 12.5459
BT 422 CTRP2 6.4838 10.4936 4.1746 7.0489
BT 159 CTRP2 6.5317 16.4483 1.2427 18.3073
BT 232 CTRP2 6.6586 14.6308 2.2517 14.4715
BT 172 CTRP2 6.6675 14.3188 2.4143 13.8386
BT 187 CTRP2 6.6735 16.7622 1.2003 18.1811
BT 328 CTRP2 6.7167 8.8954 5.1328 2.7118
BT 333 CTRP2 6.7982 10.8517 4.2364 6.2605
BT 320 CTRP2 6.8929 11.9579 3.7616 8.0612
BT164 CTRP2 6.92 12.4795 3.5242 8.9871
BT 482 CTRP2 6.927 14.3168 2.6187 12.5857
BT 504 CTRP2 7.4904 14.4571 2.9739 10.252
BT 179 CTRP2 8.2076 17.4867 2.0105 12.7307
BT 224 CTRP2 11.2116 23.1321 1.327 10.9266
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 0.7738 6.3661 0.2014 36.7619
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
M059J GDSC1; GDSC2 -1.7205 0.2778 -1.7276 44.5605
SNU-466 CTRP2 -1.4014 0.7242 -1.4022 49.605
H4 GDSC1; GDSC2 -1.2443 3.9391 -1.8426 41.9843
D-566MG GDSC1; GDSC2 -1.0859 3.3222 -1.4886 40.2435
GI-1 GDSC1; GDSC2 -0.9784 3.1984 -1.338 39.2326
Onda 11 GDSC1; GDSC2 -0.8275 4.1196 -1.447 38.7669
MOG-G-UVW GDSC1; GDSC2 -0.238 4.728 -1.0209 34.5643
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -0.1455 6.752 -1.7416 36.3778
LNZTA3WT4 GDSC1; GDSC2 0.318 3.6433 -0.0494 28.1977
D-542MG GDSC1; GDSC2 0.5586 6.4975 -0.9064 30.7572
D-247MG GDSC1; GDSC2 0.576 5.1002 -0.2956 28.2265
KG-1-C CTRP2 0.6924 7.5906 -0.2813 38.2064
D283 Med GDSC1; GDSC2; CTRP2 0.784 4.1768 0.6849 35.3623
D-336MG GDSC1; GDSC2 1.385 9.5231 -1.5108 29.8369
CAS-1 GDSC1; GDSC2; CTRP2 1.5788 10.3001 -0.4071 35.3909
D-423MG GDSC1; GDSC2 1.816 8.3697 -0.5455 24.7793
M059K CTRP2 2.0804 13.5044 -1.3465 37.5473
MOG-G-CCM GDSC1; GDSC2 2.4548 12.1834 -1.8507 27.5995
Hs 683 GDSC1; GDSC2; CTRP2 2.5831 8.2144 1.513 26.8064
Onda 10 GDSC1; GDSC2 2.698 9.329 -0.2162 20.6151
SNU-626 CTRP2 2.7673 7.8681 1.8455 25.1076
PFSK-1 GDSC1 2.8526 6.6422 -0.1681 7.4717
ONS-76 GDSC1; GDSC2; CTRP2 2.9665 11.8803 0.2852 29.4959
KALS-1 GDSC1; GDSC2; CTRP2 3.1031 10.9664 0.8455 27.4783
SF539 GDSC1; GDSC2; CTRP2 3.1377 9.6191 1.4927 25.2764
SF268 GDSC1; GDSC2; CTRP2 3.2689 8.0139 2.318 21.9543
YH-13 GDSC1; GDSC2; CTRP2 3.3045 10.6163 1.2075 27.3515
DK-MG GDSC1; GDSC2; CTRP2 3.4611 11.7576 0.8269 26.5664
SK-MG-1 GDSC1; GDSC2 3.5206 11.9249 -0.8151 20.9285
D-245MG GDSC2 3.5724 9.495 0.4416 16.9172
LN-405 GDSC1; GDSC2 3.7635 11.683 -0.4966 18.9811
D-263MG GDSC1; GDSC2 3.8654 8.7214 1.0607 11.1868
42-MG-BA GDSC1; GDSC2; CTRP2 3.9653 11.5803 1.3977 23.4063
T98G GDSC1; GDSC2; CTRP2 3.9838 8.4441 2.8774 17.8867
D-392MG GDSC1; GDSC2 4.0059 11.8598 -0.3913 17.928
D-502MG GDSC1; GDSC2 4.0967 8.8499 1.174 10.0562
KNS-60 CTRP2 4.1346 11.735 1.4844 22.6861
Daoy GDSC1; GDSC2; CTRP2 4.1463 11.1382 1.7831 21.605
LN-18 GDSC1; GDSC2; CTRP2 4.1885 10.1827 2.2799 19.6662
U-251MG GDSC1; GDSC2; CTRP2 4.2622 16.1315 -0.5519 28.3871
AM-38 GDSC1; GDSC2; CTRP2 4.294 7.6707 3.5334 14.5035
SF295 GDSC1; GDSC2; CTRP2 4.3536 7.5907 3.6295 13.9688
SNU-1105 CTRP2 4.4741 15.4091 -0.0033 26.4678
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 4.6061 13.518 1.0503 23.0083
GB-1 GDSC1; GDSC2; CTRP2 4.8543 12.9483 1.5566 20.7244
Becker GDSC1; GDSC2; CTRP2 4.901 13.2835 1.4328 21.048
SF126 GDSC1; GDSC2; CTRP2 5.2381 10.7672 2.9815 14.4609
SW1783 GDSC1; GDSC2; CTRP2 5.6294 7.1421 5.1204 5.0949
KNS-81-FD GDSC1; GDSC2 5.721 7.752 2.6474 0.5875
U-87MG ATCC GDSC1; CTRP2 5.7391 14.4496 1.5848 18.7039
SNU-489 CTRP2 5.9205 15.9272 0.9994 20.313
SNB-75 GDSC1; GDSC2; CTRP2 5.924 15.9243 1.0037 20.2918
SNU-201 CTRP2 6.009 15.0664 1.5039 18.437
KNS-81 CTRP2 6.0471 10.9723 3.5827 10.3236
SW1088 GDSC1; GDSC2; CTRP2 6.1143 15.7646 1.2424 19.1205
YKG-1 GDSC1; GDSC2; CTRP2 6.3231 13.122 2.7351 13.2347
GaMG GDSC1; GDSC2; CTRP2 6.5047 17.236 0.8274 19.7145
A-172 GDSC1; GDSC2; CTRP2 6.6225 12.3507 3.3591 10.1757
8-MG-BA GDSC1; GDSC2; CTRP2 6.9907 14.3839 2.6347 13.1967
KINGS-1 GDSC1; GDSC2 7.1656 15.5132 0.054 9.7924
U-118MG GDSC1; GDSC2; CTRP2 7.2171 16.2357 1.89 14.8007
NMC-G1 GDSC1; GDSC2; CTRP2 7.2177 9.1205 5.3391 1.324
CCF-STTG1 CTRP2 7.4362 10.8476 4.68 3.539
TM-31 CTRP2 7.8715 19.4078 0.8176 18.2626
GOS-3 CTRP2 10.0106 27.2361 -1.4554 21.0513
GMS-10 CTRP2 10.9981 24.9276 0.3435 14.8635
KNS-42 GDSC1; GDSC2; CTRP2 12.5069 24.1436 1.6444 8.5188
DBTRG-05MG GDSC1; GDSC2; CTRP2 12.5887 26.8128 0.475 11.8671
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 -0.9087 2.5316 -1.1058 38.1158
ETK-1 GDSC1; GDSC2 1.7691 9.3741 -1.079 27.045
TGBC1TKB GDSC1; GDSC2 4.3956 11.9561 -0.1363 15.8756
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-1-B CTRP2 -1.4353 4.6772 -1.7899 49.8524
JHUEM-7 CTRP2 -0.8498 3.7102 -0.9944 46.1457
HEC-251 CTRP2 0.0382 6.3497 -0.5962 41.4284
JHUEM-3 CTRP2 0.6207 8.5806 -0.7192 39.3537
HEC-151 CTRP2 0.6966 3.6722 0.6453 35.7931
ESS-1 GDSC1; GDSC2; CTRP2 1.0879 6.1555 0.6045 36.7863
KLE GDSC1; GDSC2; CTRP2 1.4464 7.7337 0.4814 33.622
JHUEM-2 CTRP2; CTRP1 1.984 8.4393 0.7886 30.9698
HEC-6 CTRP2 2.0373 7.9802 1.0238 30.0807
RL95-2 GDSC1; GDSC2; CTRP2 2.2041 8.386 1.0432 29.4971
HEC-1-A CTRP2 2.2201 8.2959 1.0959 29.281
JHUEM-1 CTRP2 2.3295 5.2978 2.1669 25.3051
HEC-59 CTRP2 4.1219 12.3034 1.1971 23.6893
HEC-265 CTRP2 4.395 12.3148 1.4472 22.1794
EFE-184 CTRP2 5.0476 14.0317 1.1924 21.5331
MFE-296 GDSC1; GDSC2; CTRP2 5.3168 13.7742 1.5576 19.6929
MFE-280 GDSC1; GDSC2 5.7969 16.782 -1.4735 18.3059
MFE-319 GDSC1; GDSC2; CTRP2 6.0595 15.0502 1.5541 19.218
EN GDSC1; GDSC2; CTRP2 6.8143 10.7427 4.3019 5.9637
HEC-108 CTRP2 6.8365 9.1179 5.1071 2.6477
HEC-50B CTRP2 8.1097 13.1827 4.0146 5.2625
AN3-CA GDSC1; GDSC2; CTRP2 10.2675 19.5349 2.4095 8.5004
Ishikawa (Heraklio) 02 ER- CTRP2 7.4029 14.1296 3.0706 10.0128
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 GDSC1; GDSC2; CTRP2 0.5379 7.536 -0.4296 39.1044
TUHR14TKB CTRP2 0.7154 5.2836 0.4174 36.3999
TK-10 GDSC1; GDSC2 1.0747 5.2227 0.1777 24.1404
KTCTL-13 GDSC1; GDSC2 1.1309 6.5592 -0.3539 26.3449
769-P GDSC1; GDSC2; CTRP2 1.4653 7.8697 0.4521 33.6391
VMRC-RCW GDSC1; GDSC2; CTRP2 1.8263 8.566 0.5712 32.1101
KTCTL-26A GDSC1; GDSC2 1.9003 5.9136 0.7104 18.581
KTCTL-21 GDSC1; GDSC2 1.9193 6.418 0.4918 19.6282
LB996-RCC GDSC1; GDSC2 2.264 11.084 -1.4726 26.9067
UO-31 GDSC1; GDSC2; CTRP2 2.2907 10.1281 0.4017 31.1321
LB1047-RCC GDSC1; GDSC2 3.0398 7.9392 0.7741 14.7979
SW156 GDSC1; GDSC2 3.0625 7.7001 0.9131 14.0043
NCC010 GDSC1; GDSC2 3.1294 8.3873 0.6271 15.3164
A-704 GDSC1; GDSC2 3.3775 5.7649 2.1464 6.4097
KTCTL-1M GDSC1; GDSC2 3.4042 6.2116 1.9451 7.4631
BFTC-909 GDSC1; GDSC2; CTRP2 3.4408 10.2339 1.5196 24.3549
HA7-RCC GDSC1; GDSC2 3.5793 13.1814 -1.395 22.9985
SW13 GDSC1; GDSC2 3.7393 13.7404 -1.5437 23.1264
A-498 GDSC1; GDSC2; CTRP2 3.946 9.6161 2.3075 21.5066
KTCTL-140 GDSC1; GDSC2 4.0519 9.211 0.9614 11.2786
VMRC-RCZ GDSC1; GDSC2; CTRP2 4.1827 11.3017 1.7392 23.0268
786-O GDSC1; GDSC2; CTRP2 4.2112 9.856 2.4566 18.936
KMRC-3 CTRP2 4.3466 12.1246 1.4948 22.1317
KTCTL-195 GDSC1; GDSC2 4.4112 7.0513 2.268 3.6002
KMRC-20 GDSC1; GDSC2; CTRP2 4.6606 10.0582 2.7932 16.5304
LB2241-RCC GDSC1; GDSC2 4.7146 14.1561 -0.9828 18.7336
RXF 393L GDSC1; GDSC2 4.961 8.3607 2.0021 4.0646
NCC021 GDSC1; GDSC2 5.0138 8.7251 1.8664 4.6602
TUHR4TKB CTRP2 5.1345 11.4368 2.5568 16.3761
SNU-1272 CTRP2 5.1611 13.9018 1.3573 20.7259
BB65-RCC GDSC1; GDSC2 5.182 13.4344 -0.2804 14.8086
KMRC-2 CTRP2 5.4578 11.1244 3.0004 13.9102
TUHR10TKB CTRP2 5.4598 6.0576 5.4027 4.0949
KMRC-1 GDSC1; GDSC2; CTRP2 5.8203 12.8582 2.449 15.3411
SN12C GDSC1; GDSC2 6.0662 18.3097 -2.0262 19.6794
RCC10RGB GDSC1; GDSC2; CTRP2 7.1823 13.4031 3.2649 9.5992
Caki-2 CTRP2 7.5391 10.7644 4.7832 3.2389
ACHN GDSC1; GDSC2; CTRP2 7.7772 18.5243 1.1832 16.2775
Caki-1 GDSC1; GDSC2; CTRP2 9.4471 23.1562 0.1318 17.679
OS-RC-2 GDSC1; GDSC2; CTRP2 9.4796 20.1007 1.632 12.1693
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-407 GDSC1; GDSC2; CTRP2 -0.7781 5.5487 -1.2719 46.0822
CL-34 CTRP1 -0.4947 6.6451 -2.0581 52.2237
SNU-81 GDSC1; GDSC2; CTRP2; CTRP1 -0.1599 4.3792 -0.3554 41.8078
HCC2998 GDSC1; GDSC2 0.0001 4.3265 -0.6199 31.9961
GP5d GDSC1; GDSC2 0.0062 5.5633 -1.0843 33.6938
SNU-175 GDSC2; CTRP1 0.1604 9.2759 -2.5748 40.2907
CCK-81 GDSC1; GDSC2; CTRP2 0.2183 5.0903 -0.081 39.6119
HCT 15 GDSC1; GDSC2; CTRP2 0.2585 5.0227 -0.0232 39.3118
NCI-H508 GDSC1; GDSC2; CTRP2; CTRP1 0.3977 7.6453 -0.6191 40.0168
NCI-H747 GDSC1; GDSC2; CTRP2 0.4796 6.1377 -0.0544 38.5119
SW48 GDSC1; GDSC2; CTRP2 0.7171 7.6842 -0.2874 38.1272
SNU-C2B GDSC1; GDSC2 1.0669 7.0701 -0.6523 27.8264
COLO 320HSR GDSC1; GDSC2 1.1157 5.8747 -0.0616 25.1014
LoVo GDSC1; GDSC2; CTRP2; CTRP1 1.1206 7.9371 0.0568 35.8639
SW626 GDSC1; GDSC2 1.1917 9.0715 -1.4762 30.3881
SNU-C2A CTRP2 1.2152 9.5756 -0.4821 36.7638
HT115 GDSC1; GDSC2; CTRP2; CTRP1 1.2392 5.55 0.9266 33.024
SNU-C1 GDSC1; GDSC2; CTRP2 1.2973 6.7764 0.6469 35.8452
NCI-H716 GDSC1; GDSC2; CTRP2 1.5707 7.8928 0.5568 32.9919
LS411N GDSC1; GDSC2; CTRP2 1.8478 5.5443 1.5908 28.8291
HCT 8 CTRP2; CTRP1 1.8861 5.37 1.6711 28.4322
CaR-1 GDSC1; GDSC2 1.9412 8.3804 -0.4334 23.8944
SNU-283 GDSC2 2.0501 11.0808 -1.6625 30.7648
CL-11 GDSC1; GDSC2; CTRP2 2.1592 7.5803 1.3043 28.797
SW1417 GDSC1; GDSC2; CTRP2 2.2545 10.094 0.3794 33.1325
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 2.3262 7.6961 1.4404 27.8282
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 2.4461 8.3297 1.3219 27.8576
SW1463 GDSC1; GDSC2 2.5208 10.1087 -0.7602 23.4688
SNU-1033 CTRP2 2.6557 9.2397 1.1633 27.7511
DLD-1 CTRP2 2.754 7.2219 2.0748 24.329
COLO 320 CTRP2; CTRP1 2.8735 8.6475 1.641 25.5153
CL-40 CTRP1 2.877 6.8158 1.1916 20.4728
LS180 GDSC1; GDSC2; CTRP2 2.9064 10.0097 1.0831 27.284
SW948 GDSC1; GDSC2; CTRP2; CTRP1 3.0067 11.5816 0.4644 30.5208
DiFi GDSC1; GDSC2 3.0214 8.2256 0.6153 15.6715
LS513 GDSC1; GDSC2; CTRP2 3.1066 8.9571 1.7515 24.4647
SNU-1040 GDSC1; CTRP1 3.1345 7.9939 0.828 14.2583
SW480 CTRP1 3.2544 12.0229 -1.0849 30.7572
SNU-61 GDSC1; GDSC2; CTRP2; CTRP1 3.2707 10.5978 1.1823 25.9478
SNU-C5 GDSC1; GDSC2; CTRP2; CTRP1 3.2814 9.9105 1.5074 24.8292
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 3.2849 5.9702 3.0528 19.1939
GP2d CTRP2 3.3974 10.8 1.2144 25.4992
T84 GDSC1; GDSC2; CTRP2 3.5514 6.935 3.0374 18.4603
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 3.8759 8.4462 2.766 18.6026
SW1116 GDSC1; GDSC2 3.9888 9.1383 0.9491 11.4877
RKO GDSC1; GDSC2; CTRP2; CTRP1 4.0545 13.0586 0.7667 25.2335
KM12 GDSC1; GDSC2; CTRP2; CTRP1 4.0735 10.3647 2.082 20.6956
COLO201 CTRP2 4.1051 8.6279 2.4201 13.8898
C2BBe1 GDSC1; GDSC2; CTRP2 4.1719 11.851 1.4636 22.6658
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 4.2026 12.4243 1.2141 24.8212
COLO205 GDSC1; GDSC2; CTRP2 4.2593 10.3095 2.2882 19.4591
LS1034 GDSC1; GDSC2; CTRP2 4.9106 11.2781 2.4316 17.3659
SNU-503 CTRP2 4.995 17.5089 -0.5842 28.1673
SW837 GDSC1; GDSC2 5.0514 11.581 0.5299 11.3289
SW620 GDSC1; GDSC2; CTRP2; CTRP1 5.4585 14.1381 1.4995 19.5912
SK-CO-1 GDSC1; GDSC2; CTRP2 5.4594 12.6243 2.2551 16.8351
OUMS-23 CTRP2 5.4813 7.35 4.8785 6.1082
SNU-C4 CTRP2; CTRP1 5.5446 8.4047 4.4256 7.8348
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 6.7959 17.5399 0.9103 18.9013
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 6.9469 10.5279 4.503 4.9303
HCC-56 CTRP2 7.428 8.8655 5.5526 0.5333
LS123 GDSC1; GDSC2; CTRP2; CTRP1 7.9231 19.669 0.7274 17.494
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 3.6172 6.9138 1.7658 7.9394
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-878 CTRP2 -0.9644 2.5873 -1.0062 46.7577
Li-7 CTRP2 -0.287 9.3862 -1.9972 44.6032
SNU-182 CTRP2 0.3679 8.7275 -1.0454 40.8687
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 1.7609 8.3217 0.5975 32.2473
Hep-G2/C3A GDSC1; GDSC2 2.6395 8.9149 -0.0618 20.0776
SNU-387 GDSC1; GDSC2; CTRP2 3.1223 11.142 0.7831 29.2402
SNU-761 CTRP2 3.5795 10.5896 1.4922 24.0793
HLE GDSC1; GDSC2 3.652 8.6986 0.9034 12.5297
JHH-5 CTRP2 4.049 10.1968 2.1375 20.5509
HuH-6 CTRP2 4.4203 17.1275 -0.9027 28.8647
JHH-4 GDSC1; GDSC2; CTRP2 4.647 12.1326 1.7696 20.4473
Hep-G2 CTRP2; CTRP1 4.7246 10.2077 2.7815 16.426
JHH-1 GDSC1; GDSC2; CTRP2 4.7475 11.4159 2.2138 19.7634
SNU-886 CTRP2 4.9629 6.8786 4.5649 8.6811
JHH-2 GDSC1; GDSC2; CTRP2 5.2397 12.2529 2.2464 18.4418
JHH-7 GDSC1; GDSC2 5.6703 7.3172 2.7862 0.2824
SNU-398 GDSC1; GDSC2; CTRP2 5.7873 14.0866 1.8071 17.8119
Huh-7 GDSC1; GDSC2 5.9062 7.6026 2.7733 0.2357
SNU-475 GDSC1; CTRP2 6.4548 12.2535 3.2749 11.5976
PLC/PRF/5 CTRP2 6.4908 10.0151 4.4177 6.4681
HuH-1 GDSC1; GDSC2; CTRP2 6.5287 13.5634 2.6805 13.8997
SNU-423 GDSC1; GDSC2; CTRP2 6.7692 15.9281 1.6928 17.2581
SK-HEP-1 GDSC1; GDSC2; CTRP2 6.9302 13.2629 3.1442 10.5072
JHH-6 GDSC1; GDSC2; CTRP2 7.1512 7.9438 5.786 0.1168
HLF CTRP2 7.3381 11.7222 4.1979 5.9987
SNU-449 GDSC1; GDSC2; CTRP2 9.8475 19.5279 2.1475 9.922
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 225 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SBC-3 GDSC1; GDSC2 -1.6086 3.5044 -2.1098 44.6028
DMS 454 CTRP2 -1.4335 9.516 -3.2713 49.8845
NCI-H64 GDSC1; GDSC2 -1.3823 1.3189 -1.4347 47.3
HCC44 GDSC1; GDSC2; CTRP2 -1.3815 4.5865 -1.7132 49.5349
NCI-H211 GDSC1; GDSC2; CTRP2 -1.2776 1.9373 -1.2971 48.7948
DV-90 CTRP2 -0.734 5.6682 -1.2538 45.8491
Lu-134-A GDSC1; GDSC2 -0.7179 2.0037 -0.8094 36.0621
EBC-1 GDSC1; GDSC2; CTRP2 -0.6283 4.0334 -0.8035 44.7751
IST-SL1 GDSC1; GDSC2 -0.6236 2.3099 -0.7558 35.4001
NCI-H1385 CTRP2 -0.5758 7.1794 -1.5195 45.3703
COR-L311 GDSC2 -0.455 2.3015 -0.5729 38.4168
NCI-H1437 GDSC1; GDSC2 -0.4511 4.7592 -1.2615 36.3576
BEN GDSC1; GDSC2; CTRP2 -0.1855 3.7863 -0.2971 41.7888
IST-SL2 GDSC1; GDSC2 -0.1686 4.2658 -0.7813 33.3761
NCI-H526 GDSC1; GDSC2; CTRP2 -0.1626 5.5216 -0.5942 42.2852
HCC95 CTRP2 -0.1051 8.0053 -1.2887 43.0917
NCI-H748 GDSC1; GDSC2 -0.0871 3.4648 -0.4384 35.7868
Lu-135 GDSC1; GDSC2 -0.0265 2.0558 -0.0803 29.8135
NCI-H1304 GDSC1 0.0503 2.9008 -0.6615 18.2483
LCLC-97TM1 GDSC1; GDSC2; CTRP2 0.0877 7.7074 -0.976 41.8602
NCI-H1184 CTRP2 0.2347 5.5143 -0.1593 39.7271
NCI-H810 GDSC1; GDSC2; CTRP2 0.2466 4.3608 0.0845 39.0868
NCI-H847 GDSC1; GDSC2 0.3554 1.3581 0.3541 26.2075
NCI-H1734 GDSC1; GDSC2; CTRP2 0.3681 4.7476 0.1495 38.4422
Ms-1 GDSC1; GDSC2 0.3753 3.8643 -0.0567 27.9914
LC-2/ad GDSC1; GDSC2 0.3769 5.9566 -0.8593 31.3156
NCI-H2135 GDSC1; GDSC2 0.413 4.5279 -0.2478 28.6829
Lu-139 GDSC1; GDSC2 0.517 3.6741 0.1579 26.4251
LXF 289 GDSC1; GDSC2; CTRP2 0.5833 5.8917 0.1255 37.6735
NCI-H446 GDSC1; GDSC2; CTRP2 0.6683 5.4811 0.3209 36.841
NCI-H2073 CTRP1 0.7039 7.603 -1.2595 43.656
HCC1833 CTRP2; CTRP1 0.7975 8.5091 -0.5029 38.2814
A-427 GDSC1; GDSC2 0.8404 7.3397 -1.0021 30.0184
NCI-H2804 GDSC1; GDSC2 0.9477 5.8581 -0.2266 26.4727
NCI-H1155 GDSC1; GDSC2; CTRP2 0.9983 3.0826 0.9891 33.6482
LUDLU-1 CTRP2 1.0093 7.271 0.1715 38.3808
Calu-3 GDSC1; GDSC2; CTRP2 1.0495 7.6074 0.0987 36.0134
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 1.1509 4.6396 1.0115 33.0578
NCI-H2722 GDSC1; GDSC2 1.1635 5.9614 -0.0513 24.8777
NCI-H146 GDSC1; GDSC2 1.1923 4.5669 0.5698 21.8015
SBC-1 GDSC1; GDSC2 1.1926 5.1496 0.3315 22.9636
LC-1/sq GDSC1; GDSC2 1.2068 7.1529 -0.552 26.9062
LOU-NH91 GDSC1; GDSC2; CTRP2 1.226 6.2206 0.7368 33.6481
NCI-H2731 GDSC1; GDSC2 1.2262 6.5562 -0.2569 25.5737
Lu-99 CTRP2 1.2538 5.9816 0.8333 33.261
Lu-99A GDSC1; GDSC2 1.271 4.5434 0.6626 21.0481
NCI-H23 GDSC1; GDSC2; CTRP2 1.2908 4.7551 1.1433 32.1563
DMS 273 GDSC1; GDSC2; CTRP2 1.4108 8.9839 -0.0355 37.1279
NCI-H2171 GDSC1; GDSC2; CTRP2 1.428 4.1353 1.3711 30.945
NCI-H1341 GDSC1; GDSC2; CTRP2 1.502 4.4085 1.4193 30.5385
NCI-H740 GDSC2 1.5447 5.1042 0.7161 22.4144
DMS 53 GDSC1; GDSC2; CTRP2 1.5629 4.7001 1.4443 30.2537
RERF-LC-KJ GDSC1; GDSC2 1.5631 3.8751 1.2273 17.1342
NCI-H1373 CTRP2 1.6103 9.713 -0.1251 34.6376
NCI-H358 GDSC1; GDSC2; CTRP2 1.704 6.2098 1.2614 30.395
NCI-H2087 GDSC1; GDSC2; CTRP2 1.7254 9.3435 0.1494 33.5808
SK-LU-1 GDSC1; CTRP2; CTRP1 1.7499 7.8896 0.7502 31.8388
NCI-H2347 GDSC1; GDSC2 1.7918 9.4377 -1.089 27.0083
NCI-H522 GDSC1; GDSC2; CTRP2 1.868 9.8776 0.0735 35.2274
HCC1588 CTRP2 1.939 8.7349 0.6229 31.5999
NCI-H1648 GDSC1; GDSC2 1.9776 7.4085 0.073 21.4841
NCI-H510A GDSC1; GDSC2; CTRP2 1.9787 6.4383 1.4939 30.822
NCI-H2803 GDSC1; GDSC2 1.991 9.5474 -0.9593 25.8785
NCI-H3255 GDSC1; GDSC2; CTRP1 2.0183 4.9758 1.2579 15.3334
NCI-H187 GDSC1 2.0234 4.4089 0.3437 5.0157
LB647-SCLC GDSC1; GDSC2 2.0476 6.2418 0.6999 18.1493
SW1271 GDSC1; GDSC2; CTRP2 2.064 8.7567 0.7461 30.8435
NCI-H2081 GDSC1; GDSC2; CTRP1 2.071 7.3908 0.1697 20.7218
COR-L303 GDSC2 2.1155 6.6676 0.5614 21.0324
HCC366 GDSC1; GDSC2; CTRP2 2.1183 8.1103 1.0602 29.7112
COR-L47 CTRP2 2.1331 7.5041 1.3041 28.8792
NCI-H2227 GDSC1; GDSC2 2.1915 4.6556 1.5769 13.065
SHP-77 GDSC1; GDSC2; CTRP2 2.2341 6.9805 1.5974 27.5809
COR-L105 GDSC1; GDSC2; CTRP2 2.2384 10.2878 0.278 33.4543
NCI-H520 GDSC1; GDSC2; CTRP2 2.2492 7.5172 1.4241 28.1201
NCI-H596 GDSC1; GDSC2; CTRP1 2.263 8.0348 0.0337 20.765
NCI-H2795 GDSC1; GDSC2 2.2975 7.1403 0.5038 18.3577
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 2.3591 7.4105 1.5813 27.2505
HCC2279 CTRP2 2.3635 10.5391 0.2947 31.207
NCI-H1963 GDSC1; GDSC2 2.3719 8.7176 -0.2034 23.9934
RERF-LC-A1 CTRP2 2.4045 8.9347 1.0306 28.9232
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 2.4287 7.4583 1.6387 26.8411
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 2.4496 7.5564 1.6249 26.825
VMRC-LCD GDSC1; GDSC2; CTRP2 2.4622 8.0823 1.4371 27.4251
NCI-H2009 GDSC1; GDSC2; CTRP2 2.4707 7.8268 1.5454 27.033
HCC33 GDSC1; GDSC2 2.5854 7.1694 0.7545 18.2808
COR-L51 CTRP2 2.5971 9.4325 1.0198 28.3819
NCI-H69 GDSC1; GDSC2; CTRP2 2.6145 9.5169 1.0012 28.3889
COR-L279 GDSC1; GDSC2 2.6861 7.5825 0.6411 16.488
NCI-H835 GDSC1; GDSC2 2.6957 7.2068 0.8358 15.4459
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 2.7047 9.3122 1.1828 27.5445
NCI-H524 GDSC1; GDSC2 2.7255 6.126 1.3964 12.3475
NCI-H2461 GDSC1; GDSC2 2.7289 9.8055 -0.4264 21.4576
NCI-H290 GDSC1; GDSC2 2.7482 8.04 0.4692 17.185
NCI-H1975 GDSC1; GDSC2 2.8498 9.363 -0.1006 19.6508
NCI-H2373 GDSC1; GDSC2 2.8857 10.7675 -0.7704 22.458
DMS 114 GDSC1; GDSC2; CTRP2 2.9048 8.2816 1.8254 24.7783
EPLC-272H GDSC1; GDSC2; CTRP2 2.9099 6.8354 2.3791 22.7661
Sq-1 CTRP2; CTRP1 2.9561 7.0366 2.3591 22.7024
COR-L23 GDSC1; GDSC2; CTRP1 2.9613 9.0884 0.1329 18.2372
NCI-H1666 GDSC1; GDSC2; CTRP2 3.0364 13.0236 -0.1861 30.5519
NCI-H82 GDSC1; GDSC2 3.0781 5.8613 1.8437 8.8816
NCI-H1435 GDSC1; GDSC2; CTRP2 3.1395 8.4434 2.0044 23.4681
NCI-H209 GDSC1; GDSC2 3.1464 9.2942 0.1883 17.4608
SK-MES-1 GDSC1; GDSC2; CTRP2 3.1473 11.9188 0.4447 28.5492
NCI-H1876 GDSC1; GDSC2; CTRP1 3.1718 6.0852 1.8133 8.7969
CPC-N GDSC1; GDSC2 3.184 7.7932 0.9703 13.3726
NCI-H1703 GDSC1; GDSC2; CTRP2 3.1859 8.6777 1.9536 23.5213
NCI-H647 GDSC1; GDSC2; CTRP2 3.2039 11.4516 0.7195 27.5858
RERF-LC-Sq1 GDSC1; GDSC2 3.2083 7.1601 1.3074 11.4892
NCI-H2810 GDSC1; GDSC2 3.2894 6.94 1.4857 10.2995
ChaGo-K-1 GDSC1; GDSC2; CTRP2 3.3015 7.4761 2.5667 20.9366
NCI-H2141 GDSC1; GDSC2; CTRP2 3.3096 8.1979 2.2848 21.9635
NCI-H1944 GDSC1; GDSC2; CTRP2 3.3493 11.318 0.9249 28.1316
NCI-H1650 GDSC1; GDSC2; CTRP2 3.3771 11.324 0.9494 26.4076
NCI-H1299 GDSC1; GDSC2; CTRP2 3.4199 10.0694 1.5741 24.2227
NCI-H1581 GDSC1; GDSC2; CTRP2 3.435 6.2094 3.1499 18.3868
DMS 79 GDSC1; GDSC2 3.4485 6.5597 1.8073 8.1186
NCI-H1395 CTRP2 3.451 15.1223 -0.8029 32.5298
NCI-H1836 GDSC1; GDSC2; CTRP1 3.4924 6.1519 2.0464 6.6832
NCI-H1568 GDSC1; GDSC2; CTRP2 3.5039 10.7359 1.3494 24.7654
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 3.5277 7.5816 2.7658 19.5508
NCI-H322M GDSC1; GDSC2 3.5731 8.6823 0.8481 13.0152
LK-2 GDSC1; GDSC2 3.585 8.0793 1.1588 11.3352
T3M-10 CTRP2; CTRP1 3.6026 11.0452 1.3013 24.6656
NCI-H2405 GDSC1; GDSC2; CTRP2 3.6154 8.5166 2.4673 20.4408
PC-14 GDSC1; GDSC2; CTRP2 3.6418 8.7697 2.3837 20.6853
NCI-H2591 GDSC1; GDSC2 3.6886 11.2746 -0.3531 18.5451
HCC4006 CTRP2; CTRP1 3.696 8.7626 2.4424 20.3187
NCI-H2029 GDSC1; GDSC2; CTRP2 3.7282 7.9038 2.8455 18.6939
COR-L88 GDSC1; GDSC2; CTRP2 3.7719 7.2611 3.1513 17.4041
NCI-H1693 GDSC1; GDSC2; CTRP2 3.7903 11.467 1.2837 24.2367
COR-L321 GDSC1; GDSC2 3.8153 7.1997 1.7772 7.4189
NCI-H2291 GDSC1; GDSC2; CTRP2 3.8197 9.0253 2.4509 19.9591
NCI-H1869 GDSC1; CTRP2 3.8404 9.5608 2.2278 20.7475
EMC-BAC-2 GDSC1; GDSC2 3.8726 11.1987 -0.1675 17.2563
NCI-H720 GDSC1; GDSC2 3.8935 6.8966 1.9857 6.1034
COLO 668 GDSC1; GDSC2; CTRP2 3.9398 8.2422 2.9208 17.8345
NCI-H1105 GDSC1; GDSC2; CTRP2; CTRP1 3.9563 9.1358 2.5385 20.5585
NCI-H250 GDSC2 3.958 7.3135 1.8282 7.7462
HOP-62 GDSC1; GDSC2; CTRP2 3.9784 14.818 -0.1641 28.0773
NCI-H2066 GDSC1; GDSC2 3.9974 9.4157 0.8181 12.1501
Lu-65 GDSC1; GDSC2; CTRP2 4.0377 8.3364 2.98 17.3459
NCI-H345 GDSC1; GDSC2 4.0645 6.1643 2.4617 3.1931
COR-L32 GDSC1; GDSC2 4.1884 6.8706 2.2074 4.3117
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 4.2239 10.4366 2.1934 21.1968
NCI-H1770 GDSC1; GDSC2 4.2388 8.581 1.4118 8.4798
NCI-H661 GDSC1; GDSC2; CTRP2 4.2974 9.9353 2.5031 18.543
NCI-H1573 GDSC1; GDSC2; CTRP2 4.3431 9.7658 2.6277 17.9475
NCI-H1048 GDSC1; GDSC2 4.4351 9.247 1.2281 9.0434
NCI-H1993 GDSC1; GDSC2 4.4441 11.9879 -0.1151 15.6688
NCI-H1915 GDSC1; GDSC2; CTRP2 4.4512 9.7903 2.7209 18.4757
RERF-LC-MS GDSC1; GDSC2; CTRP2 4.505 10.3249 2.5166 17.9855
NCI-H2106 CTRP2 4.5111 12.4247 1.501 21.7163
HCC2935 CTRP2; CTRP1 4.531 9.5915 2.8927 16.4469
NCI-H1436 GDSC1; GDSC2 4.5323 8.5698 1.6254 6.7515
UMC-11 GDSC1; GDSC2 4.5751 11.6604 0.1454 14.1711
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 4.5853 11.0189 2.2566 18.7912
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 4.6589 12.6371 1.5325 21.2594
EMC-BAC-1 GDSC1; GDSC2 4.7195 9.0366 1.5287 6.9052
NCI-H3122 GDSC1; GDSC2 4.7335 9.0054 1.553 7.6431
HCC2108 CTRP2; CTRP1 4.7432 12.0817 1.8829 19.8128
NCI-H2595 GDSC1; GDSC2 4.7629 12.5175 -0.1372 15.0617
NCI-H1688 GDSC1; GDSC2 4.7751 11.8167 0.2164 13.4031
NCI-H1651 GDSC1; GDSC2; CTRP2 4.7895 12.4885 1.7249 20.2771
NCI-H2369 GDSC1; GDSC2 4.7935 10.2456 0.9966 9.5161
NCI-H513 GDSC1; GDSC2 4.8035 9.9636 1.1401 8.7612
NCI-H2228 GDSC1; GDSC2; CTRP2 4.8077 12.0531 1.956 19.3964
NCI-H650 GDSC1; GDSC2; CTRP2 4.8438 10.3842 2.8076 16.0447
Lu-165 GDSC1; GDSC2 4.8654 11.5904 0.3928 12.3712
NCI-H1838 GDSC1; GDSC2; CTRP2 4.901 9.8183 3.1366 14.5942
NCI-H2126 CTRP2 4.9173 11.0879 2.5311 16.9645
MOR/CPR CTRP2 4.9418 11.2444 2.4767 17.1204
HCC1359 CTRP1 4.943 5.824 3.0405 0.0996
NCI-H226 GDSC1; GDSC2; CTRP2 4.9467 12.2194 2.0003 18.9161
PaCa-3 GDSC1; GDSC2 5.0203 13.3939 -0.3783 15.5729
NCI-H1563 GDSC1; GDSC2; CTRP2 5.0546 6.0382 4.9658 6.9046
LC-1/sq-SF CTRP2 5.0563 14.5137 0.9605 22.2738
NCI-H2444 GDSC1; GDSC2; CTRP2 5.0592 9.5962 3.3929 13.1892
NCI-H1339 CTRP2 5.1131 12.4787 2.0216 19.7051
HCC1195 CTRP2; CTRP1 5.1158 9.7146 3.3877 13.0818
LK2 CTRP2 5.1929 8.7289 3.94 10.6371
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 5.2036 12.3271 2.1775 17.6815
EKVX GDSC1; GDSC2; CTRP2 5.2307 13.544 1.5967 19.7429
HOP-92 GDSC1; GDSC2; CTRP2 5.2487 13.9922 1.3894 20.4242
NCI-H2170 GDSC1; GDSC2; CTRP2 5.2789 10.5209 3.14 13.7302
ABC-1 GDSC1; GDSC2 5.3366 9.1542 1.8645 4.1793
NCI-H889 CTRP2 5.3785 8.3901 4.279 8.8142
NCI-H1092 GDSC1; GDSC2 5.4142 12.2996 0.4345 11.0791
NCI-H1781 GDSC1; GDSC2; CTRP1 5.4256 13.6842 -0.2279 14.0838
COLO 699 CTRP2; CTRP1 5.5026 14.7553 1.2296 20.4199
NCI-H2286 CTRP2 5.5299 9.6424 3.1364 7.6336
SBC-5 GDSC1; GDSC2; CTRP2 5.5503 6.0681 5.4986 3.4733
COR-L95 GDSC1; GDSC2; CTRP2 5.5586 7.7836 4.7429 6.4866
NCI-H2196 GDSC1; GDSC2; CTRP2 5.5754 7.1315 5.0735 5.0868
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 5.6551 13.9262 1.7746 18.2028
NCI-H2818 GDSC1; GDSC2 5.6564 15.2159 -0.8096 16.0629
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 5.6833 14.1256 1.6991 18.4146
NCI-H2869 GDSC1; GDSC2 5.7039 12.1427 0.7037 9.2625
SW1573 GDSC1; GDSC2 5.7514 14.0234 -0.1644 13.17
HCC1438 CTRP2 5.7785 14.6215 1.5323 18.8067
A-549 GDSC1; GDSC2; CTRP2 5.9567 13.4698 2.2584 15.7959
NCI-H838 GDSC1; GDSC2; CTRP2 5.9715 12.3316 2.8398 13.5008
NCI-H2085 GDSC1; GDSC2; CTRP2 5.9923 14.3639 1.8411 17.2729
NCI-H727 GDSC1; GDSC2; CTRP2 6.0052 15.2566 1.4056 18.7842
NCI-H196 GDSC1; GDSC2; CTRP2 6.0263 16.292 0.9055 20.4025
NCI-H1792 GDSC1; GDSC2; CTRP2 6.0825 14.4508 1.8729 16.9776
HCC78 GDSC1; GDSC2; CTRP2 6.2617 14.0562 2.2181 15.3481
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 6.3445 7.4306 5.5827 1.4324
NCI-H322 CTRP2 6.3463 13.9767 2.327 15.7642
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 6.499 11.5026 3.6843 9.0599
NCI-H1355 GDSC1; GDSC2; CTRP2 6.7632 16.2775 1.5139 16.9475
HCC1171 CTRP2 6.7648 18.2508 0.5307 20.1457
NCI-H1623 GDSC1; GDSC2; CTRP2 6.7833 14.1701 2.5797 12.9925
KNS-62 GDSC1; GDSC2; CTRP2 6.9511 14.8689 2.3631 13.5217
IA-LM GDSC1; GDSC2; CTRP2 7.0324 16.9731 1.38 16.9151
Calu-1 CTRP2 7.2007 10.2618 4.8039 3.3588
NCI-H292 GDSC1; GDSC2; CTRP2 7.2134 14.6101 2.6925 11.8051
Calu-6 GDSC1; GDSC2; CTRP2 7.2472 11.7832 4.1051 6.0967
RERF-LC-Ad2 CTRP2 7.8161 13.5135 3.6633 7.0349
LCLC-103H GDSC1; GDSC2; CTRP2 7.8297 9.0364 5.6532 0.1391
NCI-H1793 GDSC1; GDSC2; CTRP2 7.8396 19.8745 0.5625 18.1424
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 8.4711 18.8167 1.5503 13.9262
RERF-LC-Ad1 CTRP2 9.9912 26.7168 -1.2157 19.6521
Hs 888.Lu CTRP2 5.9481 16.7508 0.6107 22.7012
⏷ Show the Full List of 225 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 1.8017 7.4751 -0.1263 22.9893
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 -1.2071 2.9311 -1.2856 48.3725
P-STS CTRP2 0.7196 3.9715 0.6406 35.7271
H-STS CTRP2 6.2612 10.4532 4.0179 8.1045
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -0.7205 4.0809 -0.9098 45.3824
Yamato-SS CTRP2 0.6225 6.9279 -0.1355 38.1476
Hs 633.T GDSC1; GDSC2 -1.2973 2.2864 -1.4789 41.3889
SW872 GDSC1; GDSC2 -0.9677 4.846 -1.8491 40.5195
KYM-1 GDSC1; GDSC2; CTRP2 -0.8163 2.3875 -0.8425 45.7585
Rh41 GDSC1; GDSC2; CTRP2 -0.0978 2.9104 -0.1283 41.0084
G-402 GDSC1; GDSC2; CTRP2 0.1488 5.5133 -0.2528 42.8597
G-401 GDSC1; GDSC2; CTRP2 1.2168 6.8325 0.5414 36.4492
STS-0421 GDSC1; GDSC2 1.3501 7.0078 -0.3429 25.5057
A-204 GDSC1; GDSC2; CTRP2 1.5954 8.44 0.3752 33.4122
RD GDSC1; GDSC2; CTRP2 2.1177 7.7265 1.2056 29.2487
VA-ES-BJ GDSC1; GDSC2 2.221 10.9079 -1.4236 26.8662
MFH-ino GDSC1; GDSC2 2.6814 9.1782 -0.1558 20.3886
TE 617.T CTRP2 2.6936 7.992 1.7185 25.7707
TTC-709 CTRP2 2.7524 9.214 1.2745 27.1058
Rh18 GDSC1; CTRP2 2.8803 9.5448 1.2626 26.7758
SW684 GDSC1; GDSC2 3.6541 11.1703 -0.329 18.526
EW-8 GDSC1; GDSC2 3.7716 5.9328 2.3697 4.2606
SW982 GDSC1; GDSC2; CTRP2 3.9008 14.6692 -0.1629 28.264
Rh30 GDSC1; GDSC2 4.2958 8.0325 1.7207 6.7072
GCT GDSC1; GDSC2; CTRP2 4.6473 13.2987 1.1959 22.4332
TE 441.T GDSC1; GDSC2; CTRP2 4.9854 11.1926 2.5421 17.9463
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 5.3634 16.5215 0.228 23.8396
Hs 729.T CTRP2 5.5932 13.3886 1.9898 17.547
Tm87-16 CTRP2 5.6254 10.2862 3.565 11.2454
SK-LMS-1 GDSC1; GDSC2; CTRP2 5.7721 14.1264 1.7743 19.0383
SK-UT-1 GDSC1; GDSC2; CTRP2 5.8249 12.6512 2.5563 14.9143
BT-16 CTRP2 6.2085 7.4213 5.4875 2.0425
BT-12 CTRP2 6.5926 8.673 5.1542 2.807
RKN GDSC1; GDSC2; CTRP2 6.7131 13.9432 2.6375 12.8949
MES-SA GDSC1; GDSC2; CTRP2 9.0476 25.2348 -1.1774 21.8045
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.3781 6.3124 -0.2146 39.2749
FU-OV-1 GDSC1; GDSC2; CTRP2 -0.6242 6.7969 -1.4518 45.525
OC 314 GDSC1; GDSC2; CTRP2 -0.0804 4.8178 -0.3493 41.4538
A2780 GDSC1; GDSC2; CTRP2 0.026 6.6026 -0.6842 41.6364
JHOS-4 GDSC2 0.6204 9.0771 -2.0306 37.21
JHOC-5 CTRP2; CTRP1 1.1541 6.427 0.5983 34.3041
OVCAR-4 GDSC1; GDSC2; CTRP2 1.4758 7.5584 0.5762 33.256
ONCO-DG-1 CTRP2 1.6509 7.0466 0.9429 31.5826
Caov-3 GDSC1; GDSC2; CTRP2; CTRP1 1.9316 7.7246 1.0066 30.4708
MCAS CTRP2 1.9449 6.1629 1.5376 28.6965
Kuramochi GDSC1; GDSC2; CTRP2 2.1014 10.8847 -0.1261 33.0885
RMUG-S CTRP1 2.1885 10.4419 -1.2217 35.6813
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 2.2249 13.3912 -1.1513 34.9761
COV644 CTRP2; CTRP1 2.4226 9.565 0.7822 29.6334
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 2.5638 8.4701 1.3894 27.28
COV434 CTRP2; CTRP1 2.6706 10.2032 0.7569 28.9755
IGROV-1 GDSC1; GDSC2; CTRP2 2.7009 8.2513 1.6228 26.0811
OVSAHO CTRP2 2.977 12.6702 -0.0761 30.4325
OVCAR-8 GDSC1; GDSC2; CTRP2 3.6103 8.9074 2.2908 21.1188
SNU-119 CTRP2 3.6622 10.3267 1.6964 23.1499
ES-2 GDSC1; GDSC2 3.7518 5.789 2.4257 3.9962
SNU-8 CTRP2 3.8757 10.0112 2.0543 21.3014
OVCAR-5 GDSC1; GDSC2; CTRP2 3.8941 14.2845 0.019 27.7964
OAW28 GDSC1; GDSC2; CTRP2 3.9979 12.1524 1.1531 24.1429
COV362 CTRP2; CTRP1 4.4449 9.8446 2.689 17.4586
OVCAR-3 GDSC1; GDSC2 4.4955 11.4628 0.1833 14.1683
Caov-4 GDSC1; GDSC2 4.5371 11.2294 0.3296 13.3769
OV7 CTRP2; CTRP1 4.6688 13.6579 1.0382 24.3097
OVKATE GDSC1; GDSC2 4.7518 9.4505 1.3519 7.7654
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 5.1211 11.355 2.5852 16.2949
SNU-840 CTRP2; CTRP1 5.1338 16.5476 0.0159 24.9339
HEY A8 CTRP2 5.2278 13.0843 1.8227 18.9414
SK-OV-3 GDSC1; GDSC2; CTRP2 5.2425 13.4656 1.646 19.5428
OVTOKO GDSC1; GDSC2; CTRP2 5.2924 15.855 0.4992 23.1933
OAW42 GDSC1; CTRP2; CTRP1 5.5877 10.5477 3.4017 12.8102
OVK18 GDSC1; GDSC2; CTRP2; CTRP1 5.7271 16.252 0.6738 21.7427
JHOM-1 CTRP2; CTRP1 5.9404 14.4638 1.7477 17.7141
TOV-112D GDSC1; GDSC2; CTRP2 6.0059 15.8826 1.0931 20.934
JHOS-2 GDSC1; GDSC2; CTRP2 6.0462 16.1045 1.0158 20.0062
TOV-21G GDSC1; GDSC2; CTRP2 6.4759 12.4826 3.1774 11.9193
DOV13 GDSC1; GDSC2; CTRP2 7.3052 11.2923 4.3823 4.8936
ES2 CTRP2 7.9641 12.7988 4.1017 5.1123
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 8.1108 17.995 1.6915 14.0081
OV56 GDSC1; GDSC2; CTRP2 8.6546 14.9461 3.5354 6.8267
EFO-21 GDSC1; GDSC2; CTRP2 10.2191 19.9995 2.1633 9.4008
OVISE GDSC1; GDSC2; CTRP2 10.5556 20.0957 2.3276 8.4415
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.9051 9.7045 4.8725 4.0337
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1; GDSC2; CTRP2 0.8908 5.3995 0.5822 35.2891
IST-Mes1 GDSC1; GDSC2; CTRP2 3.5163 13.1566 0.2111 29.7483
MSTO-211H GDSC1; GDSC2; CTRP2 4.0477 5.9645 3.8867 13.8633
NCI-H2052 GDSC1; GDSC2; CTRP2 4.0995 14.6312 0.0391 27.2396
NCI-H2452 GDSC1; GDSC2; CTRP2 4.9769 14.083 1.1041 21.9837
MPP 89 GDSC1; GDSC2; CTRP2 6.7414 17.2339 1.0194 18.6502
JL-1 CTRP2 11.4972 21.7745 2.1248 8.0645
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2; CTRP2 -0.6175 2.4854 -0.6426 47.4705
LNCaP clone FGC GDSC1; GDSC2; CTRP2 0.2381 6.9644 -0.5654 40.5493
22Rv1 GDSC1; GDSC2; CTRP2 3.4991 14.9319 -0.6653 30.5104
NCI-H660 GDSC2 4.6154 6.0684 2.8184 0.8777
PaCa-3 CTRP2 6.3161 7.2214 5.6641 1.144
PC-3 GDSC1; GDSC2 6.544 9.5417 2.3134 1.0851
DU145 GDSC1; GDSC2; CTRP2 7.0698 15.0895 2.3454 13.3794
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 1.1121 8.0373 0.0109 36.0056
A-253 GDSC1; GDSC2; CTRP2 7.3321 16.3802 1.9066 15.3962
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 1.0896 5.3248 0.1501 24.2148
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-620 CTRP2 -1.3857 1.0518 -1.3884 49.5016
ECC10 GDSC1; GDSC2; CTRP2 -1.1509 2.8118 -1.2164 47.9994
GSS CTRP2 -1.1464 0.6051 -1.1466 47.9064
Fu97 GDSC1; GDSC2; CTRP2 -0.9174 2.7365 -0.9672 46.4605
RERF-GC-1B GDSC1; GDSC2 -0.8413 4.1998 -1.4884 38.9545
SNU-16 GDSC1; GDSC2; CTRP2 -0.4565 3.9751 -0.611 46.7323
RF-48 GDSC1; GDSC2 0.416 6.47 -1.0406 31.8183
SNU-719 CTRP2 0.4522 6.1454 -0.0864 38.6936
SNU-1 GDSC1; GDSC2; CTRP2 0.5882 6.0353 0.0924 40.1589
NUGC-4 GDSC1; GDSC2; CTRP2 0.8067 5.4418 0.4809 35.8855
HSC-39 GDSC1; GDSC2 1.368 2.7633 1.312 17.5107
HGC-27 GDSC1; GDSC2; CTRP2 1.8386 8.8533 0.4691 32.3576
MKN28 GDSC1; GDSC2 1.8481 7.3917 -0.0419 25.1478
KE-39 CTRP2 1.9691 10 0.1259 32.8634
MKN74 CTRP2 2.3349 12.1094 -0.4466 33.1549
GCIY GDSC1; GDSC2 2.3943 12.5337 -2.0782 30.8735
SNU-601 CTRP2 2.4029 7.4233 1.6239 26.9705
IM95 GDSC1; GDSC2; CTRP2 2.5027 7.5344 1.6901 26.4391
AGS GDSC1; GDSC2; CTRP2 2.6566 8.9518 1.2868 27.3457
SNU-5 GDSC1; GDSC2; CTRP2 2.7218 8.1361 1.6911 25.7829
TMK-1 GDSC1; GDSC2 2.7461 10.0807 -0.5486 21.9331
SH-10-TC CTRP2 3.0068 7.6554 2.1833 23.1963
MKN1 GDSC1; GDSC2; CTRP2 3.1607 10.5349 1.1015 26.5121
OCUM-1 GDSC1; GDSC2 3.165 12.321 -1.309 25.9829
23132/87 GDSC1; GDSC2; CTRP2 3.1955 6.8129 2.6961 20.7621
SNU-216 CTRP2 3.7771 9.8159 2.0472 21.5829
GSU CTRP2 3.8024 8.6157 2.6161 19.3739
Hs 746.T GDSC1; GDSC2; CTRP2 4.2059 9.1903 2.7626 18.9584
NUGC-3 GDSC1; GDSC2; CTRP2 4.5453 13.3521 1.0767 23.0648
NCI-N87 GDSC1; CTRP2 4.6348 9.116 3.2191 14.8917
KATO III GDSC1; GDSC2; CTRP2 4.6506 9.4195 3.0901 15.3715
SCH GDSC1; GDSC2 4.7915 7.2673 2.3975 2.3894
HuG1-N CTRP2 5.0818 15.4541 0.5151 24.9535
TGBC11TKB GDSC1; GDSC2 5.4058 10.1885 1.4309 6.2059
MKN7 GDSC1; GDSC2; CTRP2 5.4159 10.1624 3.4407 12.2023
ECC12 GDSC1; GDSC2; CTRP2 5.5586 14.1603 1.5748 19.1157
SK-GT-2 GDSC1; GDSC2 5.7261 11.9684 0.8006 8.7584
LMSU CTRP2 7.2431 19.4924 0.2914 21.0521
MKN45 GDSC1; GDSC2; CTRP2 7.4164 8.5223 5.6793 0.2126
SNU-668 CTRP2 7.7108 9.4077 5.4657 0.5628
SNG-M GDSC1; GDSC2; CTRP2 1.5617 6.2311 1.1 31.3862
SNU-1077 CTRP2 1.6769 7.0724 0.9624 31.4363
SNU-685 CTRP2 4.8404 14.0633 0.9921 22.6569
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1; GDSC2 -1.2075 2.3413 -1.3921 40.6332
HTC-C3 GDSC1; GDSC2 -0.1265 4.5434 -0.8337 33.3835
8305C GDSC1; GDSC2; CTRP2 0.0228 4.7604 -0.2264 40.7501
CAL-62 GDSC1; GDSC2; CTRP2 0.1872 8.3346 -1.0924 41.6411
K5 GDSC1; GDSC2 0.6991 5.7159 -0.4222 28.2777
ASH-3 GDSC1; GDSC2 0.9951 4.7309 0.2956 23.8809
BHT-101 GDSC1; GDSC2; CTRP2 1.2307 8.2078 0.0746 35.4333
IHH-4 GDSC1; GDSC2 2.248 6.5372 0.7503 17.2482
SW579 CTRP2 2.6829 8.8622 1.3519 27.0526
8505C GDSC1; GDSC2; CTRP2 2.7016 11.7515 0.0833 30.7859
TT GDSC1; GDSC2; CTRP2 3.3086 8.304 2.2396 22.1337
FTC-238 CTRP2 3.6142 12.2857 0.723 28.1121
CGTH-W-1 GDSC1; GDSC2; CTRP2 3.6788 6.9723 3.1609 17.631
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 4.0504 12.6129 0.9796 24.5742
FTC-133 GDSC1; GDSC2; CTRP2 4.4207 10.0791 2.5537 18.0451
B-CPAP GDSC1; GDSC2; CTRP2 4.5489 10.1976 2.6197 17.4788
TT2609-C02 GDSC1; GDSC2; CTRP2 4.5838 12.13 1.7126 22.0801
WRO GDSC1; GDSC2 5.7152 16.7085 -1.4967 18.5519
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB30-HNC GDSC1; GDSC2 -2.1814 12.6782 -6.4735 51.8404
PCI-06A GDSC1; GDSC2 -1.6829 1.4982 -1.7714 44.4398
KOSC-2 GDSC1; GDSC2 -0.9785 6.3922 -2.4594 41.7941
PCI-04B GDSC1; GDSC2 -0.7751 4.788 -1.6208 38.9786
JHU-011 GDSC1; GDSC2 -0.3004 4.3729 -0.9611 34.6408
KON GDSC1; GDSC2 -0.1943 3.2061 -0.4844 32.3099
YD-10B CTRP2 -0.1727 3.5367 -0.2555 41.6369
Detroit 562 GDSC1; GDSC2; CTRP2 0.3202 5.0197 0.0444 38.8994
SCC-4 GDSC1; GDSC2; CTRP2 1.1124 6.8083 0.4355 34.9087
BICR 18 CTRP2 1.2219 8.6711 -0.1124 38.171
OSC-19 GDSC1; GDSC2 1.3544 6.563 -0.132 24.5542
HO-1-N-1 GDSC1; GDSC2 1.4198 9.5265 -1.4798 29.6164
UPCI-SCC-090 GDSC1; GDSC2 1.5017 8.666 -0.9857 27.5862
Ca9-22 GDSC1; GDSC2 1.5286 6.6756 -0.0118 23.3895
BICR 10 GDSC1 1.6048 16.7601 -6.1396 33.4238
FaDu GDSC1; GDSC2; CTRP2 1.7007 8.3998 0.503 32.712
SNU-1214 CTRP2 1.7015 9.1713 0.1952 33.5402
JHU-029 GDSC1; GDSC2 1.7095 8.3045 -0.6141 25.4181
PCI-38 GDSC1 1.873 7.4555 -1.2742 15.649
BB49-HNC GDSC1 1.9839 8.2726 -1.5939 17.1121
SCC-25 GDSC1; GDSC2; CTRP2 2.6479 9.5966 1.0011 28.2909
PCI-15A GDSC1; GDSC2 2.6854 8.4119 0.2288 18.5597
SAS GDSC1; GDSC2 2.6955 8.6704 0.1093 19.1076
SAT [Human HNSCC] GDSC1; GDSC2 2.7246 8.6227 0.1586 21.0245
HSC-3 GDSC1; GDSC2; CTRP2 2.7307 11.2547 0.3414 30.0042
BICR 31 GDSC1; GDSC2; CTRP2 2.7545 11.1139 0.4298 31.517
DOK GDSC1; GDSC2 3.0586 13.9433 -2.2097 27.0476
BICR 78 GDSC1; GDSC2 3.2959 9.9492 -0.0134 18.0193
HO-1-u-1 GDSC1; GDSC2 3.3946 10.1364 -0.0249 17.8128
BICR 16 CTRP2 3.5747 9.9603 1.7789 23.0879
LB771-HNC GDSC1; GDSC2 3.6492 13.2025 -1.3483 22.6519
BICR 6 CTRP2 4.2218 8.9557 2.8868 17.2361
PE/CA-PJ49 CTRP2 4.2948 12.4143 1.3053 22.9046
SNU-899 CTRP2 4.3328 11.7219 1.6778 21.5235
CAL-33 GDSC1; GDSC2; CTRP2 4.742 8.8721 3.4388 13.7468
NCI-H3118 GDSC1; GDSC2 4.8017 10.3046 0.9737 9.6165
SKN-3 GDSC1; GDSC2 4.8216 13.2789 -0.4687 16.3884
YD-8 CTRP2 4.8307 16.2794 -0.1167 25.9643
CAL-27 GDSC1; GDSC2; CTRP2 4.8973 12.0711 2.0287 20.1114
BHY GDSC1; GDSC2; CTRP2 4.9406 13.3399 1.4403 20.9328
JHU-022 GDSC1; GDSC2 4.981 13.0407 -0.2337 15.0241
BICR 22 GDSC1; GDSC2; CTRP2 4.9962 10.6252 2.8309 16.6407
PE/CA-PJ34 (clone C12) CTRP2 5.0125 15.5829 0.39 25.4915
HSC-2 GDSC1; GDSC2; CTRP2 5.2184 12.9479 1.8822 19.8968
PCI-30 GDSC1; GDSC2 5.2575 8.0727 2.2997 2.2569
OSC-20 GDSC1; GDSC2 5.2627 11.1022 0.9062 9.0717
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 5.2698 13.4791 1.6633 20.5878
SNU-1041 CTRP2 5.56 14.9195 1.197 20.4077
SNU-1076 CTRP2 6.1732 17.4354 0.4558 21.5072
BICR 56 CTRP2 6.1856 15.4806 1.4434 18.295
SCC-15 GDSC1; GDSC2 6.272 17.7463 -1.6041 17.8531
HSC-4 GDSC1; GDSC2; CTRP2 7.3368 15.6903 2.2516 13.2701
PE/CA-PJ41 (clone D2) CTRP2 7.5347 18.0671 1.2254 17.521
SCC-9 GDSC1; GDSC2; CTRP2 8.511 27.1943 -2.5518 25.7035
SNU-46 CTRP2 10.4621 25.4482 -0.2682 16.5635
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC1; GDSC2; CTRP2 -0.5008 5.8857 -1.0558 44.5172
5637 GDSC1; GDSC2; CTRP2 -0.0868 4.3346 -0.2695 41.3077
VM-CUB-1 CTRP2 0.4089 6.1821 -0.144 38.996
JMSU-1 CTRP2 1.7093 10.0841 -0.1793 34.4456
SW780 GDSC1; GDSC2 1.8472 9.9759 -1.3019 27.6011
BC-3C CTRP2 2.3686 10.9158 0.1313 33.5391
647V GDSC1; GDSC2; CTRP2 2.4737 6.4126 2.0411 27.02
SCaBER CTRP2 2.6911 15.8289 -1.8621 36.6254
UM-UC-1 CTRP2 3.0991 14.6733 -0.917 33.7401
253J CTRP2 3.3085 7.8159 2.4401 21.3892
U-BLC1 CTRP2 3.3913 7.7137 2.5687 20.6755
RT-4 GDSC1; GDSC2; CTRP2 3.6093 10.1425 1.7295 23.1718
KU-19-19 GDSC1; GDSC2; CTRP2 3.9342 11.1344 1.5813 22.852
HT-1376 GDSC1; GDSC2; CTRP2 4.2562 10.5639 2.1637 19.936
HT-1197 GDSC1; GDSC2; CTRP2 4.2563 10.993 1.9579 22.0161
KMBC-2 CTRP2 4.6346 7.8724 3.7946 12.5828
SW1710 GDSC1; GDSC2; CTRP2 4.6388 12.1265 1.765 20.4828
TCCSUP GDSC1; GDSC2; CTRP2 5.4369 13.6911 1.7037 18.9176
CAL-29 GDSC1; GDSC2; CTRP2 5.6269 11.6363 2.8933 13.9859
J82 GDSC1; GDSC2; CTRP2 6.1393 19.0592 -0.384 23.9461
UM-UC-3 GDSC1; GDSC2; CTRP2 6.2072 11.806 3.2981 11.1893
RT-112 GDSC1; GDSC2; CTRP2 6.278 14.4339 2.0427 15.9712
639V GDSC1; GDSC2; CTRP2 7.8108 16.2716 2.3178 12.2399
T24 GDSC1; GDSC2; CTRP2 9.8385 23.1863 0.3924 16.3139
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BPH-1 GDSC1; GDSC2 -3.1133 0.5146 -3.1789 56.3943
TC-YIK GDSC1; GDSC2 -2.1899 1.5104 -2.3129 48.7708
OV17R GDSC1; GDSC2 -2.0549 4.6866 -2.9682 48.1762
Ca Ski GDSC1; GDSC2 -1.8919 2.7777 -2.2292 46.5685
KGN GDSC1; GDSC2 -1.6826 8.0771 -3.9021 46.7397
NCC-IT GDSC1; GDSC2 -1.579 2.8641 -1.9089 49.3065
NT2-D1 GDSC1; GDSC2 -1.4891 5.1113 -2.5066 44.4896
PA-1 GDSC1; GDSC2 -1.0501 1.8863 -1.1479 44.1678
NEC8 GDSC1; GDSC2 -0.9988 0.9768 -1.0134 38.2237
OVMIU GDSC1; GDSC2 -0.9967 2.6802 -1.2327 38.9998
MS751 GDSC1; GDSC2 -0.8482 2.953 -1.1338 37.9027
SiSo GDSC1; GDSC2 -0.7747 3.4712 -1.1905 37.7168
HT-3 GDSC1; GDSC2 -0.4895 5.1203 -1.4372 37.0755
DSH1 GDSC1; GDSC2 -0.0425 4.9045 -0.8771 33.1696
OVCA420 GDSC1; GDSC2 0.0301 6.1086 -1.2847 34.2595
C-4-I GDSC1; GDSC2 0.4216 4.7741 -0.3315 29.0092
ME-180 GDSC1; GDSC2 0.6564 10.6544 -2.7484 35.7396
ACC-OV7 GDSC1; GDSC2 0.7981 6.8126 -0.8039 29.4345
CAL-39 GDSC1; GDSC2 1.3069 6.0859 0.0383 23.9413
SW954 GDSC1; GDSC2 1.5975 9.2594 -1.1831 30.8178
HEC-1 GDSC1; GDSC2 1.6179 9.1249 -1.0985 27.6152
SKN GDSC1; GDSC2 2.0414 7.2704 0.2002 20.6694
C-33 A GDSC1; GDSC2 2.1774 11.059 -1.5374 27.3891
SKG-IIIa GDSC1; GDSC2 2.3049 8.5425 -0.1778 21.6154
SiHa GDSC1; GDSC2 2.4624 11.5793 -1.5433 26.5628
PWR-1E GDSC1; GDSC2 2.4793 6.691 0.8923 15.7906
UWB1.289 GDSC1; GDSC2 2.6852 5.4685 1.6808 10.9143
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 2.8583 10.6553 -0.738 22.4032
JEG-3 GDSC1; GDSC2 3.0055 7.4588 0.9842 13.7819
OVCA433 GDSC1; GDSC2 3.2094 9.9349 -0.0788 18.5553
JAR GDSC1; GDSC2 3.2515 4.9884 2.4293 5.1576
JHOS-3 GDSC1; GDSC2 3.3968 7.8363 1.1268 11.9794
HEY GDSC1; GDSC2 3.6645 12.4176 -0.9437 21.075
PEO1 GDSC1; GDSC2 4.5516 10.3403 0.7774 11.1288
DoTc2 4510 GDSC1; GDSC2 4.8207 10.2885 0.9949 9.4709
SW756 GDSC1; GDSC2 5.1825 10.228 1.2691 7.3975
LB831-BLC GDSC1; GDSC2 5.3371 16.141 -1.4955 19.3181
SW962 GDSC1; GDSC2 5.3943 21.483 -4.0946 26.6932
HeLa GDSC1; GDSC2; CTRP2 9.8147 19.2697 2.2479 9.6168
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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