Details of the Drug

General Information of Drug (ID: DM1RWMY)

Drug Name
Plasma derived factor VIII PEGylated liposomal
Synonyms LongAte; NecLip-pdFVIII; Plasma derived factor VIII (PEGylated liposomal (NecLip), hemophilia A), Recoly
Indication
Disease Entry ICD 11 Status REF
Factor VIII deficiency 3B10 Phase 3 [1]
Cross-matching ID
TTD ID
D09APA

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor VIII (F8) TT1290U FA8_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Factor VIII deficiency
ICD Disease Classification 3B10
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor VIII (F8) DTT F8 1.08E-22 0.89 1.82
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Recombinant factor VIII in the management of hemophilia A: current use and future promise. Ther Clin Risk Manag. 2009; 5: 391-402.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2607).