Details of the Drug

General Information of Drug (ID: DM1SWOY)

Drug Name
MANUMYCIN A
Synonyms
manumycin; Manumycin A; Ucfi-C; UNII-OIQ298X4XD; AC1O5PHE; OIQ298X4XD; CHEBI:29623; C31H38N2O7; 52665-74-4; 2,4-Decadienamide, N-(5-hydroxy-5-(7-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-7-oxo-1,3,5-heptatrienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-2,4,6-trimethyl-; (2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-cyclopenten-1-yl)amino]-7-oxo-hepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-deca-2,4-dienamide; ( )-Manumycin A; BSPBio_001231; SCHEMBL12519093
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 550.6
Logarithm of the Partition Coefficient (xlogp) 4.1
Rotatable Bond Count (rotbonds) 12
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C31H38N2O7
IUPAC Name
(2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyldeca-2,4-dienamide
Canonical SMILES
CCCC[C@@H](C)/C=C(\\C)/C=C(\\C)/C(=O)NC1=C[C@]([C@H]2[C@@H](C1=O)O2)(/C=C/C=C/C=C/C(=O)NC3=C(CCC3=O)O)O
InChI
InChI=1S/C31H38N2O7/c1-5-6-11-19(2)16-20(3)17-21(4)30(38)32-22-18-31(39,29-28(40-29)27(22)37)15-10-8-7-9-12-25(36)33-26-23(34)13-14-24(26)35/h7-10,12,15-19,28-29,34,39H,5-6,11,13-14H2,1-4H3,(H,32,38)(H,33,36)/b8-7+,12-9+,15-10+,20-16+,21-17+/t19-,28-,29-,31+/m1/s1
InChIKey
TWWQHCKLTXDWBD-MVTGTTCWSA-N
Cross-matching ID
PubChem CID
6438330
ChEBI ID
CHEBI:29623
CAS Number
52665-74-4
TTD ID
D0C2UY

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CAAX farnesyltransferase beta (FNTB) TT7WZIJ FNTB_HUMAN Inhibitor [1]
Farnesyl protein transferase (Ftase) TTXQKM3 FNTA_HUMAN ; FNTB_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [2]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [2]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Gene/Protein Processing [2]
GTPase HRas (HRAS) OTWQN0DP RASH_HUMAN Gene/Protein Processing [3]
GTPase KRas (KRAS) OT78QCN8 RASK_HUMAN Gene/Protein Processing [2]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Post-Translational Modifications [2]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Protein Interaction/Cellular Processes [4]
Mitochondrial enolase superfamily member 1 (ENOSF1) OT65D3ZK ENOF1_HUMAN Gene/Protein Processing [5]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Protein Interaction/Cellular Processes [6]
Signal transducer and activator of transcription 3 (STAT3) OTAAGKYZ STAT3_HUMAN Post-Translational Modifications [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Farnesyl protein transferase (Ftase) DTT FNTB; FNTA 5.43E-01 -0.1 -0.4
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 145 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.7814 1.4422 0.7814 27.516
JK1 CTRP2 1.6219 5.853 1.0252 24.0245
JM1 CTRP2 0.3252 0.985 0.3252 30.5587
KHM-1B CTRP2 -2.603 8.6715 -4.5547 50.0556
NU-DUL-1 CTRP2; CTRP1 -0.9314 1.1936 -0.9359 39.007
KE-37 CTRP2 -0.1825 1.3119 -0.1833 33.9479
PF-382 CTRP2 -0.0941 1.5562 -0.096 33.3619
SU-DHL-5 CTRP1 -0.0647 1.5654 -0.0665 70.5403
NU-DHL-1 CTRP2 -0.0112 1.4881 -0.0122 32.8061
ST486 CTRP2 0.381 1.0513 0.381 30.1866
GA-10 CTRP2 0.385 0.9587 0.385 30.1599
RS4;11 CTRP2 0.3995 1.9005 0.3664 19.5452
Daudi CTRP2 0.4281 0.9786 0.4281 29.8726
Kasumi-2 CTRP2 0.4654 1.3995 0.4654 29.6239
Mino CTRP2 0.4657 0.9218 0.4657 29.622
Peer CTRP2 0.4661 1.6687 0.4657 29.6204
WSU-DLCL2 CTRP2; CTRP1 0.4681 0.9956 0.4681 29.6661
DoHH2 CTRP2 0.5244 1.1368 0.5244 29.2306
KMS-34 CTRP2 0.5795 1.9154 0.5786 28.8658
MV4-11 CTRP2 0.5951 1.6403 0.595 28.7593
Ci-1 CTRP2 0.6074 1.0389 0.6074 28.6764
CML-T1 CTRP2 0.6138 1.5124 0.6138 28.6342
SKM-1 CTRP2; CTRP1 0.6672 1.8737 0.6667 28.3409
JeKo-1 CTRP2 0.6836 1.2565 0.6836 28.1682
RCH-ACV CTRP2 0.7057 2.4732 0.6971 28.05
SET-2 CTRP2 0.7097 1.5085 0.7097 27.9941
OPM-2 CTRP2 0.7406 1.5667 0.7406 27.7885
NCO2 CTRP2 0.7916 1.8452 0.7914 27.4491
P31/FUJ CTRP2 0.8038 1.5796 0.8038 27.3666
ALL-SIL CTRP2 0.8385 1.9411 0.8382 27.1366
RL CTRP2 0.8635 1.6312 0.8635 26.9686
RPMI-8226 CTRP2; CTRP1 0.8767 2.0789 0.8761 26.9451
MOTN-1 CTRP2 0.8947 1.8545 0.8946 26.761
SUP-T11 CTRP2 0.9127 3.5496 0.8296 26.9213
Ri-1 CTRP2 0.9327 3.3101 0.8791 26.6879
MOLT-3 CTRP2 0.9501 1.6085 0.9501 26.3907
GDM-1 CTRP2; CTRP1 0.9503 2.757 0.9372 26.4963
NCI-H929 CTRP2 1.0056 1.9356 1.0055 26.0211
PL21 CTRP2; CTRP1 1.0098 1.8562 1.0098 26.056
SEM CTRP2 1.0109 1.8067 1.0109 25.9856
P12-Ichikawa CTRP2 1.0382 1.8166 1.0381 25.8037
MOLT-16 CTRP2 1.0721 2.51 1.0684 25.5897
AML-193 CTRP2 1.0761 1.967 1.076 25.5509
KMS-20 CTRP2 1.0976 2.9123 1.0814 25.4613
DB CTRP2 1.1389 2.0866 1.1388 25.1322
SUP-T1 CTRP2 1.15 2.5764 1.146 25.0712
U-937 CTRP2; CTRP1 1.1551 2.319 1.1542 25.0906
MM1.S CTRP2 1.1894 2.1627 1.1892 24.7957
HuT 78 CTRP2 1.1985 3.4495 1.145 24.9149
Reh CTRP2 1.2343 2.4503 1.2328 24.5005
DEL CTRP2 1.2454 1.6939 1.2454 24.4214
OCI-AML-3 CTRP2; CTRP1 1.264 2.208 1.2638 24.3626
Ki-JK CTRP2 1.2668 2.2412 1.2666 24.2795
RPMI-8402 CTRP2 1.2757 1.9202 1.2757 24.2193
CA46 CTRP2 1.2877 2.3453 1.2872 24.1407
TALL-1 [Human adult T-ALL] CTRP2 1.2923 3.5951 1.2277 24.3274
SU-DHL-1 CTRP2 1.3087 1.7439 1.3087 23.999
HT CTRP2 1.3091 1.8863 1.3091 23.9963
OCI-M1 CTRP2 1.3108 1.8567 1.3108 23.9851
SUP-M2 CTRP2 1.3176 1.8828 1.3176 23.9397
EHEB CTRP2 1.3212 2.0198 1.3212 23.9157
EM-2 CTRP2 1.3344 2.1209 1.3344 23.8276
KMS-11 CTRP2; CTRP1 1.3371 2.9772 1.3249 23.9156
ME1 CTRP2 1.3525 2.0345 1.3525 23.707
OCI-Ly3 CTRP2 1.3631 2.0931 1.3631 23.6366
SUP-B15 CTRP2 1.3637 2.3688 1.3633 23.6338
HH [Human lymphoma] CTRP2 1.3647 2.7568 1.36 23.6413
KMS-26 CTRP2 1.3855 1.8829 1.3855 23.4871
A4/Fukuda CTRP2 1.3866 2.0634 1.3864 18.0117
Namalwa CTRP2 1.3991 2.0163 1.3991 23.3964
KE-97 CTRP2 1.4155 1.8803 1.4155 23.2866
NALM-6 CTRP2 1.4444 2.0949 1.4444 23.0942
Raji CTRP2 1.4455 1.9975 1.4455 23.0865
KMS-12-BM CTRP2 1.446 2.6093 1.4445 23.0885
TF-1 CTRP2 1.4502 1.9613 1.4502 23.0554
Hs 611.T CTRP2 1.4757 2.4953 1.4752 22.887
EJM CTRP2; CTRP1 1.4819 2.5949 1.4807 22.9139
M-07e CTRP2 1.4844 2.204 1.4843 22.8277
A3/Kawakami CTRP2 1.488 1.8843 1.488 22.8034
Ku812 CTRP2 1.4935 2.5609 1.4926 22.7695
BV-173 CTRP2 1.5137 2.2717 1.5136 22.6323
SK-MM-2 CTRP2 1.5264 3.1361 1.512 22.5953
KO52 CTRP2 1.5288 1.9526 1.5288 22.5309
Karpas-422 CTRP2 1.5505 2.0607 1.5505 22.3867
F-36P CTRP2 1.5658 2.6593 1.5646 22.2885
JVM-3 CTRP2 1.572 2.8183 1.5689 22.2534
BL-70 CTRP2; CTRP1 1.6044 2.0182 1.6044 22.0938
Kasumi-1 CTRP2 1.64 2.6884 1.639 21.7931
HEL 92.1.7 CTRP2 1.6553 2.121 1.6553 16.0906
U266B1 CTRP2 1.6699 2.5955 1.6695 21.5917
SU-DHL-6 CTRP2 1.6979 4.7385 1.4493 22.2675
L-363 CTRP2 1.7214 3.0784 1.7143 21.2703
MHH-CALL-4 CTRP2 1.7234 4.073 1.6196 21.5876
NOMO-1 CTRP2; CTRP1 1.7595 2.6313 1.7592 21.0608
KMS-28BM CTRP2 1.7929 4.6546 1.574 21.5294
SIG-M5 CTRP2 1.8506 2.9068 1.8489 20.3904
THP-1 CTRP2; CTRP1 1.854 3.5501 1.8255 20.5259
SU-DHL-8 CTRP2 1.8809 4.0614 1.791 20.4893
MC116 CTRP2 1.8835 3.814 1.829 20.3498
SU-DHL-10 CTRP2 1.9027 3.7597 1.8557 20.1963
HPB-ALL CTRP2 1.9152 2.7359 1.915 19.9545
KMS-27 CTRP2 1.9159 3.0707 1.9124 19.9611
HuNS1 CTRP2 1.9295 2.8939 1.9199 14.166
CMK CTRP2 1.9631 3.0974 1.9596 19.6461
MOLM-6 CTRP2 2.0253 2.9894 2.0241 19.2234
KMS-18 CTRP2 2.0624 3.1739 2.0587 18.9846
JJN-3 CTRP2 2.1733 2.9024 2.1732 18.2328
SU-DHL-4 CTRP2; CTRP1 2.1966 3.2033 2.1942 18.1552
MOLP-8 CTRP2 2.1973 3.4831 2.186 18.1103
LP-1 CTRP2; CTRP1 2.207 3.6424 2.1868 18.1458
Mono-Mac-1 CTRP2 2.2877 5.4341 1.889 18.8897
KM-H2 CTRP2 2.3125 3.7371 2.2892 17.3826
Granta-519 CTRP2 2.3371 3.8863 2.3012 17.2612
MOLM-16 CTRP2; CTRP1 2.3619 3.7988 2.3362 17.1321
LAMA-84 CTRP2 2.3768 11.9225 -0.8818 28.1338
KCL-22 CTRP2 2.4521 4.3321 2.3601 16.6879
HEL CTRP2 2.456 2.9028 2.456 16.3468
L-428 CTRP2 2.7517 3.945 2.7315 14.4426
RPMI-6666 CTRP2 2.7894 3.8969 2.7745 14.1732
HL-60 CTRP2 2.8572 3.7149 2.8531 13.6846
HD-MY-Z CTRP2 2.9259 4.3215 2.8721 13.3959
MOLP-2 CTRP2 2.9359 5.0284 2.7215 13.9015
L-1236 CTRP2 2.9449 6.6305 2.1347 16.1065
HDLM-2 CTRP2 3.09 4.9535 2.9112 12.746
OCI-Ly19 CTRP2 3.0931 4.4497 3.0309 12.31
AMO1 CTRP2; CTRP1 3.1504 4.4696 3.0904 11.9957
OCI-Ly10 CTRP2; CTRP1 3.265 4.8763 3.1256 11.5136
MHH-CALL-3 CTRP2 3.2884 7.5122 2.0937 15.3763
K-562 CTRP2 3.3099 4.228 3.292 10.7116
KYO-1 CTRP2 3.3637 4.358 3.3348 10.3907
SR CTRP2 3.5199 5.1978 3.3048 10.0185
OCI-AML-5 CTRP2 3.6327 4.1368 3.6309 8.5048
Mono-Mac-6 CTRP2 3.6823 13.5084 -0.4527 23.6956
L-540 CTRP2 3.8797 5.3015 3.6579 7.654
SUP-HD1 CTRP2 4.0026 6.7137 3.1716 9.2607
P3HR-1 CTRP2 4.3576 8.9637 2.4043 11.6289
Toledo CTRP2 4.4611 16.8313 -1.4307 24.8116
Jurkat CTRP2 4.4628 6.577 3.6779 6.099
OCI-AML-2 CTRP2 5.1494 7.934 3.5904 5.0888
BL-41 CTRP2 6.196 17.3702 -0.2857 18.1311
REC-1 CTRP2 6.2895 13.0261 1.934 9.9812
Karpas-620 CTRP2 6.5529 7.9265 4.4515 0.2893
NB4 CTRP2 6.599 7.8536 4.4966 0.1917
KMM-1 CTRP2 6.6315 12.4204 2.4722 7.3227
Karpas-299 CTRP2 6.8831 8.4188 4.4021 0.2679
⏷ Show the Full List of 145 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.4293 4.946 2.1922 17.3564
TE15 CTRP2 3.9712 6.3614 3.3042 8.8011
KYSE-150 CTRP2 2.0545 3.1293 2.0517 19.0343
KYSE-30 CTRP2 2.1258 4.4286 1.9878 19.0248
TE-5 CTRP2 2.4462 5.0476 2.1817 17.3433
KYSE-510 CTRP2 3.9005 5.134 3.7391 7.2891
KYSE-410 CTRP2 3.9963 6.3538 3.3328 8.6229
OE21 CTRP2 4.1294 5.3727 3.8977 6.0369
TE-10 CTRP2 4.6638 8.7371 2.7856 9.4035
COLO 680N CTRP2 4.7351 7.2988 3.5649 5.9883
TE-1 CTRP2 4.7419 8.2336 3.1042 7.9101
TE-14 CTRP2 5.2019 7.5896 3.8028 4.1066
TE-11 CTRP2 5.4422 7.1998 3.2958 0.7826
TE-6 CTRP2 5.6243 7.5016 2.3158 0.2734
EC-GI-10 CTRP2 5.7984 9.8605 3.1281 5.9264
KYSE-180 CTRP2 6.0119 7.7205 4.2792 1.1219
KYSE-140 CTRP2 6.1282 9.0895 3.7247 3.0508
TE-4 CTRP2 6.1504 8.6157 3.9577 2.1349
KYSE-450 CTRP2 6.742 10.6771 3.3699 3.6625
OE19 CTRP2 6.7859 8.1076 4.4769 0.1727
TE-9 CTRP2 6.8575 9.4681 3.9735 1.4028
KYSE-70 CTRP2 7.08 8.8741 4.3129 0.3677
OE33 CTRP2 7.2032 10.6081 3.666 2.116
KYSE-520 CTRP2 8.0523 16.1143 1.6576 8.482
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.2434 9.895 3.4194 4.0985
PK-59 CTRP2 2.2415 5.2646 1.8931 19.0117
BxPC-3 CTRP2 2.6545 4.6902 2.5044 15.5437
HuP-T4 CTRP2 2.8533 5.1507 2.5947 14.6128
KP-3 CTRP2 2.9763 5.8962 2.4663 14.739
PSN1 CTRP2 3.0959 5.1326 2.8645 12.8987
SW1990 CTRP2 3.598 5.969 3.0944 10.6035
Panc 08.13 CTRP2 3.6878 6.1025 3.1311 10.2203
SU.86.86 CTRP2 3.7685 4.7978 3.6926 7.8563
Panc 10.05 CTRP2 3.8597 5.3904 3.6033 7.9178
Panc 03.27 CTRP2 3.9469 4.9416 3.8495 6.7453
HPAF-II CTRP2 3.97 7.7317 2.6539 11.4583
HuP-T3 CTRP2 3.9868 11.9978 0.5682 19.6103
PaTu 8902 CTRP2; CTRP1 4.1164 4.9831 4.0249 5.6758
MIA PaCa-2 CTRP2 4.1356 5.0032 4.037 5.4936
KP-2 CTRP2 4.3513 5.1141 4.2336 4.1313
Panc 04.03 CTRP2 4.6251 5.3327 4.4298 2.6279
AsPC-1 CTRP2 4.693 7.5703 3.393 6.7965
Capan-1 CTRP2 4.7406 5.6506 4.3887 2.5248
HPAC CTRP2 4.8493 6.2838 4.1699 3.2143
DAN-G CTRP2 4.8845 6.1071 4.288 2.6479
Panc 02.03 CTRP2 4.9051 6.7745 3.9716 3.9394
PaTu 8988s CTRP2 4.928 6.2973 4.2292 2.8116
Capan-2 CTRP2 5.0583 6.7488 4.1089 3.0767
SNU-410 CTRP2 5.5469 9.9702 2.8868 7.3361
SNU-213 CTRP2 5.7478 7.6503 4.1566 1.8544
Hs 766T CTRP2 6.1053 8.1423 4.145 1.5001
QGP-1 CTRP2 6.4679 8.5984 4.1424 1.1787
PK-45H CTRP2 6.5906 9.0145 4.0284 1.4472
CFPAC-1 CTRP2 6.6313 8.0079 4.453 0.2583
SUIT-2 CTRP2 6.7215 8.1271 4.445 0.243
PaTu 8988t CTRP2 6.7762 7.7615 4.5926 0.0459
YAPC CTRP2 6.7852 7.9811 4.5211 0.1133
TCC-Pan2 CTRP2 7.2289 8.6388 4.4536 0.1133
Panc 05.04 CTRP2 7.2418 8.9566 4.3466 0.2549
L3.3 CTRP2 7.5948 13.7354 2.481 6.0003
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 10.3389 27.1401 -2.0734 16.9764
MDA-MB-435S CTRP2 1.534 2.78 1.5311 22.5061
WM266-4 CTRP2 1.8614 2.9621 1.8591 20.3202
G-361 CTRP2 2.0301 3.7336 1.993 19.3129
LOX-IMVI CTRP2 2.7189 5.0375 2.4821 15.4273
HMCB CTRP2 2.8037 3.5229 2.8026 14.0314
CJM [Human melanoma] CTRP2 2.9338 3.9078 2.9235 13.1946
WM115 CTRP2 2.9751 4.0986 2.9523 12.9616
MeWo CTRP2 3.3108 4.669 3.2237 10.9463
RPMI-7951 CTRP2 3.4222 4.5876 3.3613 10.1117
HT-144 CTRP2 3.4682 5.5912 3.1084 10.9065
Hs 294T CTRP2 3.5193 4.6982 3.444 9.5151
SK-MEL-24 CTRP2 3.5806 5.2095 3.3668 9.6102
SK-MEL-2 CTRP2 3.5904 6.12 3.0227 10.9052
WM88 CTRP2 3.6302 5.1021 3.4558 9.1347
A-375 CTRP2; CTRP1 3.7081 5.5748 3.3748 9.293
SK-MEL-5 CTRP2; CTRP1 3.718 4.8613 3.6237 8.3368
WT2-iPS CTRP2 3.751 5.6155 3.4 9.0002
Hs 852.T CTRP2; CTRP1 3.8224 4.8098 3.7503 7.5625
COLO 792 CTRP2 3.922 6.9611 2.9762 10.2517
SK-MEL-1 CTRP2; CTRP1 3.9796 5.085 3.8443 6.746
WM1799 CTRP2 4.0423 7.1633 2.9965 9.8818
Hs 944.T CTRP2 4.0888 7.3838 2.9346 10.0281
COLO 741 CTRP2 4.1447 24.843 -5.7032 33.6109
SK-MEL-3 CTRP2 4.2351 5.6424 3.8949 5.764
WM983B CTRP2 4.262 5.0953 4.1439 4.7257
RVH-421 CTRP2 4.3073 4.8394 4.2697 4.1295
UACC-62 CTRP2 4.3231 4.9216 4.2657 4.0951
Mel Ho CTRP2 4.4895 5.5111 4.2124 3.8437
Hs 688(A).T CTRP2 4.5374 5.035 4.4626 2.7343
COLO 800 CTRP2 4.589 7.6565 3.2589 7.5745
SK-MEL-28 CTRP2; CTRP1 4.6043 6.6074 3.8004 5.3529
IGR-37 CTRP2 4.613 5.2554 4.4524 2.5684
UACC-257 CTRP2 4.6751 7.2392 3.5423 6.2064
Hs 895.T CTRP2 4.7709 5.3927 4.5431 1.8157
Hs 940.T CTRP2 4.7986 6.051 4.2422 3.0136
SK-MEL-31 CTRP2 4.8635 5.8478 4.3999 2.219
IPC-298 CTRP2 5.1758 6.3385 4.4009 1.6626
COLO 829 CTRP2 5.1926 8.1054 3.5391 5.2272
Hs 934.T CTRP2 5.4857 9.0761 3.2828 5.7933
IGR-1 CTRP2 6.1155 10.6769 2.9566 6.1396
SK-MEL-30 CTRP2 6.1498 8.3697 4.0688 1.7277
Hs 839.T CTRP2 6.2652 7.3535 4.5479 0.2062
A101D CTRP2 6.3365 8.0685 4.2987 0.7942
WM793 CTRP2 6.3663 10.2404 3.3363 4.263
Hs 936.T CTRP2 6.6546 7.7014 4.5706 0.08
A2058 CTRP2 6.7534 7.6101 4.6349 0.0227
IGR-39 CTRP2 6.975 8.3748 4.453 0.1623
Mel JuSo CTRP2 7.3118 9.0783 4.3297 0.2627
K029AX CTRP2 8.2402 14.1563 2.676 4.5527
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Kelly CTRP2 1.2199 2.4427 1.2184 24.5963
SK-N-SH CTRP2 1.3974 2.5488 1.3961 23.4121
CHP-126 CTRP2 1.605 4.1258 1.4827 22.4416
SK-N-BE(2) CTRP2 2.0628 3.0992 2.0605 18.9774
NB1 CTRP2 2.465 3.8088 2.4428 16.3617
KP-N-SI9s CTRP2 2.6344 4.9401 2.4177 15.9172
CHP-212 CTRP2 2.7482 4.7501 2.5919 14.9418
SK-N-FI CTRP2 2.7741 4.4526 2.4882 9.212
SK-N-DZ CTRP2 3.4843 4.3173 3.4669 9.5472
NH-6 CTRP2 3.8066 5.3014 3.5792 8.16
SK-N-AS CTRP2 4.0441 4.8549 3.9789 5.9817
KP-N-YN CTRP2 4.2037 7.665 2.9054 9.8866
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 1.414 2.0726 1.414 23.2966
HuH-28 CTRP2 3.1118 4.1424 3.0918 12.0402
SNU-869 CTRP2 4.7829 5.5557 4.4741 2.0759
SNU-308 CTRP2 6.175 8.7723 3.9009 2.3197
SNU-1079 CTRP2 6.8946 10.5082 3.5381 2.8658
SNU-1196 CTRP2 6.9252 11.4478 3.1264 4.3692
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CADO-ES1 CTRP2 -11.8407 -10.023 -11.8407 99.3751
SK-N-MC CTRP2 1.4642 1.8019 1.4642 22.9622
HOS CTRP2 1.5536 2.0464 1.5536 22.366
SK-ES-1 CTRP2 2.3839 3.2567 2.3825 16.8325
A-673 CTRP2 2.7083 4.1986 2.6572 14.8377
MG-63 CTRP2 2.8086 4.2766 2.7532 14.1839
SaOS-2 CTRP2 3.0274 3.989 3.0156 12.5756
G-292 clone A141B1 CTRP2 3.0978 4.4837 3.03 12.2983
CAL-78 CTRP2 3.5587 5.4019 3.2759 10.0142
U2OS CTRP2; CTRP1 3.6328 5.0073 3.4904 9.0774
Hs 822.T CTRP2 3.8468 4.8556 3.7636 7.3609
TC71 CTRP2 4.0579 5.1183 3.9151 6.1741
MHH-ES-1 CTRP2 4.6582 5.646 4.314 3.021
Hs 888.T CTRP2 4.7582 5.6143 4.4227 2.3444
SJSA-1 CTRP2 4.9319 7.4103 2.0527 1.3528
SW1353 CTRP2 6.5276 9.5049 3.7769 2.3877
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 578Bst CTRP2 0.2138 10.0541 -7.1294 18.9619
MDA-MB-157 CTRP2 1.5882 4.3186 1.4271 22.6888
AU565 CTRP2 1.9099 14.5543 -8.1488 19.2156
HCC38 CTRP2 2.2085 4.813 1.9872 18.7698
BT-549 CTRP2 2.2469 4.6658 2.0661 18.369
HCC1954 CTRP2 2.3143 4.1814 2.2375 17.554
T-47D CTRP2 2.3427 3.7877 2.3165 17.1908
MDA-MB-361 CTRP2 2.6791 3.7401 2.6696 14.8909
HCC2218 CTRP2 2.8906 4.3917 2.8227 13.6805
MDA-MB-453 CTRP2 2.8987 4.0742 2.8742 13.4769
BT-20 CTRP2 2.9345 4.3364 2.879 13.3447
HCC1143 CTRP2 2.9663 7.0031 1.9963 16.5904
HCC1937 CTRP2 3.4013 6.0464 2.8562 12.0637
MDA-MB-468 CTRP2 3.7054 5.9333 3.2216 9.8176
Hs 578T CTRP2 3.8608 5.8057 3.4374 8.5567
HCC1806 CTRP2 4.0462 4.9477 3.9561 6.0575
HCC1500 CTRP2 4.0656 5.0868 3.934 6.0812
EFM-192A CTRP2 4.0666 6.2263 3.4616 7.928
MDA-MB-231 CTRP2 4.1499 8.6975 2.3489 12.3083
HCC1419 CTRP2 4.3406 5.4342 4.0941 4.6997
CAL-85-1 CTRP2 4.344 5.49 4.0735 4.7721
JIMT-1 CTRP2 4.6457 7.2917 3.4904 6.4855
CAL-120 CTRP2 4.7533 5.5736 4.4383 2.2903
ZR-75-30 CTRP2 4.9344 8.0364 3.365 6.4356
HMC-1-8 CTRP2 4.9834 5.6778 4.5832 1.2215
HCC1428 CTRP2 5.2966 7.4237 3.9567 3.3059
HDQ-P1 CTRP2 5.3409 13.3605 1.0361 15.1168
CAL-51 CTRP2 5.3767 6.984 4.229 2.0626
KPL-1 CTRP2 5.7496 6.4954 4.6577 0.1816
BT-474 CTRP2 5.9843 7.8638 4.2005 1.4252
MCF-7 CTRP2; CTRP1 6.1292 11.357 2.6449 7.4497
CAL-148 CTRP2 6.318 11.341 2.7764 6.5662
CAMA-1 CTRP2 6.595 10.3885 3.4126 3.676
ZR-75-1 CTRP2 6.6462 7.9546 4.4783 0.2085
HCC202 CTRP2 7.0819 10.1788 3.7868 1.8207
HCC1395 CTRP2 7.4648 13.4991 2.5094 6.0539
BT 286 CTRP2 -0.5595 5.5769 -1.2543 38.3157
BT 239 CTRP2 0.3173 1.1267 0.3173 30.6117
BT 112 CTRP2 0.4266 0.8105 0.4266 29.8823
BT 145 CTRP2 0.458 0.9198 0.458 29.6731
BT164 CTRP2 0.507 0.9951 0.507 29.3461
BT 416 CTRP2 0.7142 66.9068 -29.6528 47.2751
BT 231 CTRP2 0.762 2.1864 0.7599 27.6526
BT 228 CTRP2 1.263 2.2203 1.2628 24.3044
BT 248 CTRP2 1.3879 2.9763 1.3769 23.5078
BT 139 CTRP2 1.496 2.2346 1.4959 22.7502
BT 330 CTRP2 1.4993 1.9488 1.4993 22.7282
BT 159 CTRP2 1.6108 2.3373 1.6107 21.9847
BT 245 CTRP2 1.9298 2.8513 1.9291 19.8589
BT 172 CTRP2 2.0541 3.9909 1.9874 19.2544
BT 131 CTRP2 2.0897 2.8707 2.0894 18.791
BT 340 CTRP2 2.1303 2.9551 2.1299 18.5205
BT 428 CTRP2 2.298 3.0487 2.2977 17.4017
BT 482 CTRP2 2.5113 3.2521 2.5108 15.9797
BT 504 CTRP2 2.5977 3.4217 2.5961 15.4071
BT 216 CTRP2 2.6735 5.7736 2.188 16.653
BT 328 CTRP2 2.7112 3.9361 2.6899 14.7166
BT147 CTRP2 2.7419 4.4326 2.6547 14.7392
BT 498 CTRP2 2.8251 4.0061 2.8032 13.9592
BT 422 CTRP2 2.841 3.5827 2.8396 13.7837
BT 179 CTRP2 2.9584 4.9073 2.7804 13.6195
BT 359 CTRP2 3.2419 4.8487 3.1054 11.5815
BT 232 CTRP2 3.3459 4.8457 3.2197 10.8519
BT 333 CTRP2 3.4473 4.0539 3.4445 9.7445
BT 444 CTRP2 3.4641 4.4033 3.4358 9.7193
BT 320 CTRP2 4.1013 5.7044 3.7302 6.7666
BT 440 CTRP2 4.2124 4.8545 4.1626 4.8055
BT 187 CTRP2 4.7907 10.1132 2.2063 11.5564
BT 224 CTRP2 5.1265 9.1443 2.9682 7.7407
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 5.4158 8.6908 3.4205 5.3377
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AM-38 CTRP2 -7.9923 16.8626 -13.5844 61.3288
GB-1 CTRP2 1.4416 2.0474 1.4416 23.1129
SNU-466 CTRP2 1.4635 1.8163 1.4635 22.9666
D283 Med CTRP2 1.5568 2.2306 1.5567 22.3447
TM-31 CTRP2 2.1641 3.7296 2.1344 18.3941
SF539 CTRP2 2.4368 2.9167 2.4368 16.4752
SF268 CTRP2 2.6229 4.1133 2.5776 15.3873
42-MG-BA CTRP2 2.8096 3.7256 2.8042 14.0067
SF126 CTRP2 2.9322 4.2671 2.8868 13.3248
GMS-10 CTRP2 3.4334 5.4074 3.1389 10.8901
Daoy CTRP2 3.5759 5.641 3.204 10.2396
SNU-738 CTRP2 3.6335 6.2878 2.9946 10.9024
8-MG-BA CTRP2 3.6981 5.2105 3.4939 8.7937
KG-1-C CTRP2 3.8473 5.5623 3.5233 8.2592
SNB-75 CTRP2 3.8822 5.0912 3.7333 7.3644
YH-13 CTRP2 3.8868 5.2225 3.6938 7.4982
KNS-60 CTRP2 4.0977 6.3053 2.0841 2.0942
SNU-626 CTRP2 4.1965 5.2222 4.0273 5.3533
KALS-1 CTRP2 4.2082 5.681 3.8504 6.0107
M059K CTRP2 4.3164 6.7386 3.4621 7.3261
SW1088 CTRP2 4.3583 5.633 4.0248 4.929
KNS-42 CTRP2 4.3859 5.1995 4.2383 4.016
ONS-76 CTRP2 4.43 5.1473 4.3055 3.6354
Hs 683 CTRP2 4.5335 5.0219 4.463 2.744
SW1783 CTRP2 4.5349 8.4697 2.8067 9.5809
U-118MG CTRP2 4.5498 5.2141 4.4051 2.9214
SF295 CTRP2 4.6466 6.4939 3.8872 4.8219
U-251MG CTRP2 4.7904 7.8652 3.3296 6.8658
LN-229 CTRP2; CTRP1 4.8185 10.2797 2.1549 11.7804
CAS-1 CTRP2 4.8549 6.9595 3.8369 4.6042
Becker CTRP2 4.8781 6.5243 4.0741 3.5605
DK-MG CTRP2 5.139 6.6788 4.2061 2.5297
SNU-489 CTRP2 5.1872 6.8704 4.1478 2.6919
YKG-1 CTRP2 5.6306 7.7189 4.0487 2.429
CCF-STTG1 CTRP2 5.8614 9.1652 3.5112 4.265
U-87MG ATCC CTRP2 5.8814 9.5975 3.3158 5.0298
KNS-81 CTRP2 6.0865 7.8961 4.2431 1.1761
SNU-201 CTRP2 6.2027 14.5695 1.1084 13.2988
GOS-3 CTRP2 6.4408 10.0202 3.4875 3.5777
LN-18 CTRP2 6.5245 7.7853 4.4923 0.2218
SNU-1105 CTRP2 6.7029 7.793 4.5564 0.0875
GaMG CTRP2; CTRP1 6.8468 8.9696 4.1865 0.8214
DBTRG-05MG CTRP2 7.219 8.5979 4.4641 0.1038
A-172 CTRP2 7.4541 12.2289 3.0878 3.9059
T98G CTRP2 8.4846 15.5214 2.2018 5.9821
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA CTRP2 1.6266 2.5882 1.6262 21.8801
JHUEM-2 CTRP1 1.6427 3.3297 1.6214 46.8823
MFE-296 CTRP2 1.7896 3.6403 1.749 20.9288
HEC-108 CTRP2; CTRP1 2.196 2.6941 2.196 18.1509
HEC-151 CTRP2; CTRP1 2.5136 3.5318 2.5085 16.0517
HEC-6 CTRP2 2.7283 4.1091 2.6903 14.6595
ESS-1 CTRP2 3.0092 4.0629 2.9912 12.7179
KLE CTRP2; CTRP1 3.4986 4.6653 3.4301 9.7059
HEC-1-A CTRP2 3.6255 5.4382 3.3344 9.6024
RL95-2 CTRP2 3.834 6.9172 2.9106 10.7326
JHUEM-3 CTRP2 4.062 7.0258 3.0812 9.4875
JHUEM-1 CTRP2 4.0878 4.7622 4.0479 5.6005
MFE-319 CTRP2 4.5872 5.2016 4.4493 2.6483
EFE-184 CTRP2 4.6361 5.297 4.4572 2.4904
HEC-59 CTRP2; CTRP1 4.8 5.6356 4.4577 2.1868
HEC-50B CTRP2 5.0527 8.6131 3.1739 7.0149
JHUEM-7 CTRP2 5.5768 7.9107 3.92 3.0233
HEC-251 CTRP2 5.9923 8.3544 3.9818 2.2278
HEC-1-B CTRP2 6.723 12.5054 2.4939 7.1053
EN CTRP2 7.0387 9.9707 3.8533 1.6403
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 3.1116 3.6797 3.1111 12.0513
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 2.5964 3.8121 2.5797 15.4666
KMRC-3 CTRP2 3.5288 7.2021 2.476 13.243
RCC10RGB CTRP2; CTRP1 3.9682 5.2681 3.769 7.0604
TUHR14TKB CTRP2 3.9987 6.5453 3.2466 8.9655
TUHR4TKB CTRP2 4.2318 5.2333 4.0609 5.1255
CAL-54 CTRP2 4.4107 5.0818 4.3092 3.676
786-O CTRP2 4.4997 6.6859 2.9751 3.1213
KMRC-2 CTRP2 4.5023 4.8728 4.4742 2.796
769-P CTRP2 4.7271 5.4665 4.4661 2.2345
BFTC-909 CTRP2 4.7983 6.0085 4.2632 2.9264
TUHR10TKB CTRP2 4.8725 18.8367 -2.0868 25.6492
VMRC-RCZ CTRP2 4.9757 7.052 3.8911 4.1433
OS-RC-2 CTRP2 5.1683 7.3349 3.9033 3.7444
VMRC-RCW CTRP2 5.8506 11.4581 2.3807 8.9075
Caki-1 CTRP2 6.1325 8.2245 4.1239 1.5479
SNU-1272 CTRP2 6.1883 8.9886 3.8094 2.6502
A-498 CTRP2 6.6316 8.0801 4.4263 0.3102
KMRC-20 CTRP2 6.7419 8.6054 4.2717 0.6153
Caki-2 CTRP2 6.746 8.1043 4.4628 0.2053
ACHN CTRP2 6.9808 10.2253 3.7124 2.162
KMRC-1 CTRP2 7.3246 8.8011 4.432 0.1211
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW620 CTRP2; CTRP1 1.3433 2.7006 1.3395 23.8465
SW480 CTRP1 1.5951 3.2691 1.576 47.5449
COLO 320 CTRP2; CTRP1 1.6119 4.527 1.4089 22.7447
SW48 CTRP2 1.6893 2.8097 1.6874 21.4671
HCT 116 CTRP2; CTRP1 1.8251 3.5325 1.7966 20.7185
GP2d CTRP2 1.8392 5.1675 1.4844 21.7093
SNU-175 CTRP1 2.01 4.3095 1.8876 42.1705
SNU-C5 CTRP2; CTRP1 2.6881 4.3114 2.6194 15.1059
LS123 CTRP2; CTRP1 3.0601 4.219 3.03 12.4944
SNU-81 CTRP2; CTRP1 3.099 4.555 3.0191 12.4078
CW-2 CTRP2; CTRP1 3.3101 5.6456 2.9226 12.1347
NCI-H747 CTRP2 3.3819 5.0105 3.2132 10.766
LoVo CTRP2; CTRP1 3.3959 5.5655 3.0445 11.4293
RKO CTRP2; CTRP1 3.3972 5.0244 3.2284 10.7405
T84 CTRP2 3.4813 5.7185 3.0731 11.0053
SNU-C1 CTRP2 3.5564 4.8219 3.4554 9.3593
SNU-407 CTRP2 3.5707 5.3741 3.2988 9.8934
SNU-1033 CTRP2 3.6305 5.4349 3.3409 9.5637
LS513 CTRP2 3.7517 4.605 3.7139 7.834
SNU-C4 CTRP2; CTRP1 3.773 4.5696 3.7435 7.742
SNU-C2A CTRP2 3.8458 5.5794 3.5149 8.2956
DLD-1 CTRP2 3.9581 4.9429 3.8614 6.668
COLO 678 CTRP2; CTRP1 4.1278 5.163 3.9787 5.8134
RCM-1 [Human ESC] CTRP2; CTRP1 4.1488 5.8005 3.7423 6.6729
SNU-1040 CTRP1 4.2304 5.8068 3.8228 13.1656
KM12 CTRP2; CTRP1 4.2403 5.1118 4.1181 4.9663
HCT 8 CTRP2; CTRP1 4.28 4.9734 4.2062 4.5236
SW1116 CTRP2 4.33 5.1208 4.2082 4.288
SK-CO-1 CTRP2 4.3719 5.2104 4.2191 4.1284
CL-11 CTRP2 4.3762 5.692 4.0162 4.9179
LS1034 CTRP2 4.3954 5.3679 4.1792 4.2195
NCI-H508 CTRP2; CTRP1 4.4743 5.9265 4.0098 4.7828
SW948 CTRP2; CTRP1 4.5284 5.0605 4.4473 2.9005
CL-34 CTRP1 4.551 5.4726 4.2975 7.348
NCI-H716 CTRP2 4.6193 7.8392 3.1947 7.7807
HT-29 CTRP2; CTRP1 4.628 5.5947 4.3164 3.1625
HCC-56 CTRP2 4.6551 5.1907 4.524 2.1749
SNU-61 CTRP2; CTRP1 4.7633 6.7453 3.8735 4.7104
LS411N CTRP2 4.7739 5.5073 4.4897 2.0308
SNU-503 CTRP2 5.003 6.0953 4.3908 1.9932
HT-55 CTRP2; CTRP1 5.1556 7.4249 3.8579 4.0296
C2BBe1 CTRP2 5.2378 7.3359 3.9559 3.4064
HCT 15 CTRP2 5.2446 7.0236 3.2716 1.0143
SW1417 CTRP2 5.3495 7.9891 3.7174 4.2128
LS180 CTRP2; CTRP1 5.8407 7.8188 4.1468 1.8428
CL-40 CTRP1 6.21 8.0141 4.2694 2.2135
COLO205 CTRP2 6.2113 8.9239 3.8533 2.4568
MDST8 CTRP2; CTRP1 6.2649 9.3585 3.6962 3.0534
COLO201 CTRP2 6.3652 10.6986 3.1177 5.1308
HT115 CTRP2; CTRP1 6.4455 7.651 4.5227 0.2198
CCK-81 CTRP2 6.5663 8.8863 4.0707 1.3291
OUMS-23 CTRP2 6.5677 8.2834 4.3204 0.5866
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 1.6467 3.0814 1.6379 21.7741
JHH-2 CTRP2 2.0532 3.4276 2.0403 19.0768
SNU-398 CTRP1 2.8004 4.1187 2.7664 30.5199
HLF CTRP2 3.2047 4.511 3.1404 11.5733
JHH-5 CTRP2 3.2341 5.1348 3.0143 11.9365
SNU-886 CTRP2 3.3779 5.6138 3.0032 11.5621
SNU-761 CTRP2 3.5068 7.3648 1.1701 7.2994
PLC/PRF/5 CTRP2 3.9957 5.8396 3.5627 7.7056
SNU-449 CTRP2; CTRP1 4.0574 4.9255 3.977 6.0281
SNU-423 CTRP2 4.0749 5.0597 3.953 5.9834
SNU-878 CTRP2 4.3858 5.247 4.2193 4.0896
HuH-6 CTRP2 4.4089 7.0012 3.4204 7.289
SNU-387 CTRP2 4.4314 5.2543 4.2644 3.7899
JHH-6 CTRP2; CTRP1 4.8721 6.7982 3.9405 4.2099
JHH-1 CTRP2 5.7895 7.9203 4.0569 2.1878
SK-HEP-1 CTRP2 6.5071 8.2323 4.3131 0.6414
SNU-475 CTRP2 6.5185 9.702 3.6821 2.7469
Hep 3B2.1-7 CTRP2 6.5482 9.4963 3.7927 2.3085
HuH-1 CTRP2 6.6829 8.0581 4.455 0.2375
JHH-4 CTRP2 6.7553 8.4847 4.3246 0.479
Hep-G2 CTRP2; CTRP1 6.9852 8.3616 4.474 0.1516
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 155 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Calu-3 CTRP2 -1.2085 21.9336 -9.1182 46.8575
NCI-H146 CTRP2 -1.1193 5.2333 -1.7617 41.6059
NCI-H69 CTRP2 -0.8282 5.5893 -5.6951 14.1867
NCI-H2085 CTRP2 -0.1849 11.659 -3.286 40.4551
NCI-H1963 CTRP1 0.0958 2.7735 0.0502 66.5429
NCI-H2106 CTRP2 0.1074 1.3014 0.1072 32.0122
NCI-H1876 CTRP1 0.1443 1.6154 0.1432 67.8892
NCI-H1694 CTRP2; CTRP1 0.3815 1.6698 0.381 30.2448
NCI-H810 CTRP2 0.764 2.3794 0.7587 27.6499
NCI-H1581 CTRP2 0.8177 3.0109 0.785 27.384
NCI-H1836 CTRP1 0.9061 2.5039 0.9003 57.2098
DV-90 CTRP2 1.0663 3.3352 1.0174 25.7805
NCI-H1155 CTRP2 1.1174 2.276 1.1166 25.2775
NCI-H1092 CTRP2 1.3459 2.2489 1.3457 23.7518
NCI-H211 CTRP2 1.4178 2.0533 1.4178 23.2713
DMS 79 CTRP2 1.4454 2.4153 1.4451 23.0884
NCI-H2171 CTRP2 1.4525 2.1464 1.4525 23.0401
NCI-H1568 CTRP2 1.5415 2.6936 1.5301 16.9453
NCI-H526 CTRP2 1.5621 3.0238 1.5535 22.3378
NCI-H1105 CTRP2; CTRP1 1.5684 2.5333 1.568 22.3351
COR-L51 CTRP1 1.6211 6.5635 0.7675 48.1267
COR-L23 CTRP1 1.6406 2.4451 1.6405 46.845
NCI-H1930 CTRP1 1.6704 6.0631 1.0067 47.4766
DMS 53 CTRP2 1.775 24.2426 -7.4807 39.9165
Lu-99 CTRP2 1.7953 4.6974 1.5659 21.5508
NCI-H23 CTRP2 1.8018 3.0409 1.7972 20.7257
NCI-H1341 CTRP2 1.9149 3.0854 1.9111 19.9686
COLO 699 CTRP2; CTRP1 2.1369 3.9141 2.0867 18.7149
NCI-H446 CTRP2 2.1474 3.5317 2.1318 18.4576
NCI-H2087 CTRP2 2.2287 4.2321 2.1368 18.1773
COR-L95 CTRP2 2.2462 3.5687 2.2319 17.7944
NCI-H2141 CTRP2; CTRP1 2.2543 4.5448 2.104 18.2817
NCI-H358 CTRP2 2.2611 5.5972 1.8053 19.2776
NCI-H1385 CTRP2 2.4641 3.5875 2.4555 16.3216
NCI-H596 CTRP1 2.4859 3.3569 2.4842 34.7816
RERF-LC-A1 CTRP2 2.4961 4.186 2.432 16.2977
HCC4006 CTRP2; CTRP1 2.515 3.7186 2.5016 16.07
SHP-77 CTRP2 2.5543 3.9503 2.5238 15.7943
NCI-H1184 CTRP2 2.5633 4.9202 2.3456 16.394
NCI-H841 CTRP2; CTRP1 2.6044 3.9236 2.5795 15.5133
NCI-H2081 CTRP2; CTRP1 2.6173 4.3787 2.5314 15.6376
HCC1359 CTRP1 2.6635 4.679 2.5188 33.2322
NCI-H2029 CTRP2 2.8612 5.2196 2.5818 14.6366
NCI-H1693 CTRP2 2.9334 4.3299 2.8788 13.3487
DMS 454 CTRP2 2.9411 5.683 2.509 14.6764
IA-LM CTRP2 2.9435 5.997 2.3922 15.1146
NCI-H2196 CTRP2 2.9679 4.615 2.8628 13.2956
NCI-H1781 CTRP1 2.9826 4.6687 2.8685 28.5037
COR-L88 CTRP2 2.9892 6.6426 2.1756 15.828
NCI-H2286 CTRP2; CTRP1 3.0113 4.487 2.9372 12.9716
NCI-H1650 CTRP2 3.0358 4.6203 2.9355 12.8259
COLO 668 CTRP2; CTRP1 3.1074 4.5233 3.0343 12.3277
NCI-H1793 CTRP2 3.1187 4.8721 2.9648 12.4651
HCC44 CTRP2 3.1363 4.8813 2.9816 12.3505
NCI-H1703 CTRP2 3.1366 4.1597 2.9858 6.087
EPLC-272H CTRP2 3.2481 6.8827 2.3378 14.5084
Sq-1 CTRP2; CTRP1 3.2573 4.4492 3.2089 11.2432
NCI-H2342 CTRP2; CTRP1 3.2981 5.6442 2.9103 12.2155
HCC2279 CTRP2 3.327 5.0798 3.1326 11.2251
RERF-LC-KJ CTRP1 3.3528 3.9466 3.3512 22.393
HCC1438 CTRP2 3.3799 4.9012 3.242 10.6672
NCI-H1666 CTRP2 3.383 5.2019 3.1548 10.9771
NCI-H1915 CTRP2; CTRP1 3.4558 4.7426 3.3667 10.0641
HOP-62 CTRP2 3.6107 5.7303 3.2057 10.1367
NCI-H889 CTRP2 3.6253 4.681 3.5628 8.7633
NCI-H838 CTRP2 3.6339 4.6893 3.27 3.4918
HCC1195 CTRP2; CTRP1 3.6703 4.699 3.6095 8.5355
SW1271 CTRP2 3.6742 5.3816 3.4076 9.1868
NCI-H650 CTRP2 3.6764 7.0896 2.6747 12.0758
ChaGo-K-1 CTRP2 3.7287 5.4845 3.4274 8.9573
DMS 114 CTRP2 3.7524 4.7047 3.6958 7.8952
EBC-1 CTRP2 3.7694 6.0861 3.2224 9.6448
NCI-H522 CTRP2 3.7716 5.656 3.4056 8.9221
SCLC-21H CTRP1 3.7801 4.9751 3.6605 17.1809
EKVX CTRP2 3.782 5.099 3.622 8.0719
Calu-6 CTRP2 3.7872 6.651 2.9874 10.5379
NCI-H520 CTRP2 3.7956 6.9093 2.8764 10.9656
NCI-H3255 CTRP1 3.8208 5.1194 3.6605 16.9204
NCI-H2009 CTRP2; CTRP1 3.8286 5.1819 3.6483 7.9158
HCC2935 CTRP2; CTRP1 3.8505 5.0052 3.7284 7.5559
NCI-H292 CTRP2 3.8508 5.1759 3.6712 7.6873
DMS 273 CTRP2 3.8684 5.0132 3.7428 7.3707
KNS-62 CTRP2 3.9532 5.1258 3.799 6.912
SBC-5 CTRP2 4.0119 4.8969 3.9329 6.2456
SK-LU-1 CTRP2; CTRP1 4.0139 5.6428 3.6704 7.3126
HCC2108 CTRP2; CTRP1 4.0172 5.4464 3.7538 6.9804
HCC827 CTRP2; CTRP1 4.0278 5.3263 3.8114 6.7305
NCI-H1563 CTRP2 4.0461 5.074 3.9171 6.2009
NCI-H441 CTRP2; CTRP1 4.1128 7.7675 2.7778 10.693
HARA [Human squamous cell lung carcinoma] CTRP2 4.1703 5.0839 4.0486 5.3485
HCC15 CTRP2; CTRP1 4.1999 6.0087 3.7005 6.7098
HCC1833 CTRP2; CTRP1 4.3199 6.3179 3.6742 6.5228
LCLC-97TM1 CTRP2 4.3259 8.2671 2.7211 10.3822
NCI-H2444 CTRP2 4.3435 5.3304 4.1407 4.5096
LK2 CTRP2 4.3616 4.7193 4.3506 3.6745
NCI-H2122 CTRP2; CTRP1 4.3789 5.927 3.9163 5.3944
NCI-H1755 CTRP2; CTRP1 4.3948 6.0786 3.8605 5.5827
NCI-H2030 CTRP2; CTRP1 4.4633 6.9066 3.5243 6.8121
SK-MES-1 CTRP2 4.4651 5.14 4.3458 3.383
HOP-92 CTRP2 4.4774 8.7799 2.6018 10.5558
T3M-10 CTRP2; CTRP1 4.5274 5.5642 4.2319 3.7509
NCI-H196 CTRP2 4.5414 6.9462 3.5687 6.3798
COR-L105 CTRP2 4.5856 5.8557 4.1439 3.8907
NCI-H647 CTRP2 4.5885 5.4279 4.3496 3.0428
NCI-H1734 CTRP2 4.5943 8.216 2.9851 8.7106
NCI-H1355 CTRP2 4.622 5.7201 4.2439 3.3943
NCI-H2170 CTRP2 4.6229 5.703 4.253 3.3547
LUDLU-1 CTRP2 4.6416 5.3496 4.4385 2.5517
VMRC-LCD CTRP2 4.6766 8.8194 2.7556 9.5031
NCI-H2023 CTRP2; CTRP1 4.6908 6.2259 4.0672 4.0525
CAL-12T CTRP2; CTRP1 4.7719 6.5068 3.9998 4.1631
NCI-H2073 CTRP1 4.7889 5.5313 4.4991 4.3697
NCI-H1944 CTRP2 4.8623 6.2847 4.1805 3.1441
LOU-NH91 CTRP2 4.9065 10.7655 1.9773 12.2648
NCI-H1573 CTRP2 4.9213 6.0657 4.3394 2.3603
NCI-H322 CTRP2 4.9775 5.7689 4.5332 1.4413
NCI-H1395 CTRP2 4.9789 7.04 3.8997 4.1013
NCI-H1435 CTRP2; CTRP1 5.006 8.28 3.3109 6.5992
SW1573 CTRP2 5.0122 11.1004 1.8974 12.383
NCI-H1869 CTRP2 5.0425 6.4983 4.2211 2.6342
NCI-H2110 CTRP2; CTRP1 5.1244 7.4963 3.7978 4.3366
NCI-H1339 CTRP2 5.1516 6.1211 4.4897 1.3353
NCI-H1299 CTRP2 5.1798 7.8192 3.6714 4.695
Calu-1 CTRP2 5.1966 7.9669 3.6111 4.9183
A-549 CTRP2 5.4735 6.9076 4.3301 1.5258
HCC366 CTRP2 5.479 7.3368 4.1293 2.3178
NCI-H661 CTRP2 5.5994 9.6549 3.0824 6.4364
RERF-LC-MS CTRP2 5.6272 7.5014 4.1496 2.0339
NCI-H1651 CTRP2 5.6583 10.2826 2.8167 7.4384
NCI-H226 CTRP2 5.7091 8.5788 3.6889 3.7674
BEN CTRP2 5.7257 7.077 4.4043 0.9615
HCC1171 CTRP2 5.7994 8.2254 3.9195 2.7138
HCC95 CTRP2 5.8111 7.625 4.207 1.5886
PC-14 CTRP2 5.9153 8.1025 4.0508 2.0569
MOR/CPR CTRP2 5.989 7.1578 4.5045 0.436
RERF-LC-Ad1 CTRP2 6.0286 7.0195 4.576 0.2401
HCC78 CTRP2 6.0478 8.0449 4.1558 1.5203
NCI-H727 CTRP2 6.3565 8.3766 4.1792 1.1519
NCI-H460 CTRP2; CTRP1 6.3637 7.346 4.6011 0.1156
Lu-65 CTRP2 6.4368 13.0723 2.0184 9.4144
NCI-H2405 CTRP2 6.4885 9.5645 3.7269 2.6141
RERF-LC-Ad2 CTRP2 6.6258 11.1807 3.0608 5.0028
HCC1588 CTRP2 6.6299 8.0582 4.4338 0.2958
LCLC-103H CTRP2 6.6441 7.7524 4.5493 0.1058
LXF 289 CTRP2; CTRP1 6.6668 11.3569 3.0147 5.1923
NCI-H2126 CTRP2 6.7724 8.0344 4.4977 0.146
NCI-H2228 CTRP2 6.9917 10.2726 3.6977 2.2025
NCI-H2291 CTRP2 7.1145 8.8417 4.3387 0.3069
LC-1/sq-SF CTRP2 7.1434 8.4064 4.5026 0.0775
NCI-H2172 CTRP2; CTRP1 7.2106 8.372 4.5499 0.0459
NCI-H1373 CTRP2 7.2522 8.7838 4.4118 0.1581
NCI-H1623 CTRP2 7.3914 9.0712 4.3623 0.194
NCI-H1838 CTRP2 7.3977 27.3896 -4.3321 26.0345
NCI-H1792 CTRP2 12.7383 25.5658 0.143 8.2714
Hs 888.Lu CTRP2 5.8746 9.1959 3.5055 4.2689
⏷ Show the Full List of 155 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 0.6023 1.1373 0.6023 28.7107
P-STS CTRP2 2.4417 4.7265 2.2636 17.0614
SYO-1 CTRP2 7.4897 8.7508 4.5059 0.0423
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.0333 6.1839 3.4476 8.0679
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 6.2546 9.4518 3.6354 3.2381
Yamato-SS CTRP2 6.6898 7.8549 4.5303 0.1204
KYM-1 CTRP2 1.2029 1.962 1.2029 24.7048
Rh41 CTRP2 1.3442 1.8884 1.3442 23.7625
TE 441.T CTRP2 1.5036 2.1316 1.5036 22.6995
Rh18 CTRP2 1.5218 2.0279 1.5218 22.5776
GCT CTRP2 1.7155 3.7215 1.6617 21.4678
G-401 CTRP2 1.7407 3.4457 1.7149 21.2044
A-204 CTRP2 1.9577 3.4966 1.9372 19.7392
RKN CTRP2; CTRP1 1.9848 2.841 1.9844 19.5599
SK-LMS-1 CTRP2 2.4336 3.6583 2.4206 16.5397
G-402 CTRP2 2.6314 4.2654 2.5648 15.4041
HT-1080 CTRP2; CTRP1 2.669 4.4088 2.5817 15.2978
Hs 729.T CTRP2 3.9612 4.8372 3.893 6.5448
TE 617.T CTRP2 3.9778 4.8931 3.8966 6.4809
RD CTRP2 4.2902 7.877 2.8811 9.7951
BT-12 CTRP2 5.688 15.7358 0.1288 17.6941
Tm87-16 CTRP2 5.9155 8.4133 3.9061 2.6146
SW982 CTRP2 6.773 8.4134 4.3593 0.393
BT-16 CTRP2 7.1672 8.3918 4.5158 0.0639
SK-UT-1 CTRP2 7.3775 14.7912 1.8412 8.7085
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVK18 CTRP2; CTRP1 0.4874 2.3781 0.4775 29.5705
OVCAR-8 CTRP2; CTRP1 1.1083 2.4954 1.1052 25.41
HEY A8 CTRP2 1.4169 2.6821 1.4142 23.2867
SNU-119 CTRP2 1.4999 3.5289 1.4549 22.8756
OC 314 CTRP2 1.6028 2.2127 1.6028 22.0377
A2780 CTRP2; CTRP1 1.8461 3.1175 1.8404 20.502
DOV13 CTRP2 2.3081 4.3745 2.1964 17.717
OVCAR-4 CTRP2; CTRP1 2.3674 3.6812 2.3508 17.0646
OVKATE CTRP1 2.3699 3.854 2.3396 36.6311
OV-90 CTRP2; CTRP1 2.4308 3.5351 2.4238 16.6099
COV434 CTRP2; CTRP1 2.5205 4.6024 2.3808 16.4712
RMG-I CTRP2; CTRP1 2.5307 4.7944 2.3456 16.5651
ONCO-DG-1 CTRP2 2.7554 4.456 2.6649 14.6607
ES2 CTRP2 2.9599 4.3314 2.907 13.166
EFO-27 CTRP2; CTRP1 3.1249 4.7313 3.009 12.3625
JHOC-5 CTRP2; CTRP1 3.2039 5.0225 3.0182 12.0879
OVISE CTRP2 3.3296 4.4684 3.2824 10.6811
JHOM-1 CTRP2; CTRP1 3.3456 5.9876 2.8263 12.4056
TYK-nu CTRP2; CTRP1 3.4023 4.3772 3.3742 10.2076
OVCAR-5 CTRP2 3.4397 6.1226 2.8647 11.9272
JHOS-4 CTRP1 3.4421 4.6912 3.3633 21.6884
TOV-112D CTRP2 3.6551 4.8219 3.563 8.6696
OV7 CTRP2; CTRP1 3.6951 5.4342 3.4145 9.1784
Caov-3 CTRP2; CTRP1 3.7003 6.082 3.1579 10.1573
OVTOKO CTRP2 3.7205 5.4578 3.4289 8.9747
IGROV-1 CTRP2; CTRP1 3.7238 5.4182 3.4511 8.9581
SNU-840 CTRP2; CTRP1 3.8931 6.1129 3.3429 8.9212
OVMANA CTRP1 3.9356 5.11 3.7883 15.1812
OV56 CTRP2 3.9689 5.3433 3.738 7.0966
MCAS CTRP2 3.9777 5.6747 3.6145 7.5498
RMUG-S CTRP1 4.0789 5.3534 3.8557 13.758
COV644 CTRP2; CTRP1 4.2457 7.2872 3.1362 8.9102
EFO-21 CTRP2 4.4793 5.9023 4.0196 4.6515
SNU-8 CTRP2 4.5588 6.8598 3.6271 6.0984
OAW42 CTRP2; CTRP1 4.7211 5.1653 4.6081 1.752
OVSAHO CTRP2 4.9168 8.8068 2.9652 8.1495
JHOS-2 CTRP2 5.0077 6.6073 4.1391 3.0413
Kuramochi CTRP2 5.5035 7.8081 3.9184 3.1385
COV318 CTRP1 5.6846 7.944 3.9877 5.7039
COV362 CTRP2; CTRP1 5.685 17.4495 -0.7194 20.4453
FU-OV-1 CTRP2 6.9209 8.9394 4.2202 0.6486
SK-OV-3 CTRP2 7.4801 8.925 4.4445 0.0868
OAW28 CTRP2 7.7637 12.7505 3.0323 3.7786
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 2.3082 5.321 1.9479 18.612
NCI-H28 CTRP2 2.6038 3.9126 2.5794 15.4434
MPP 89 CTRP2 4.404 5.1771 4.2664 3.8577
ACC-MESO-1 CTRP2 5.2129 7.1279 4.04 3.0979
NCI-H2452 CTRP2 5.3802 9.0698 3.2055 6.2948
IST-Mes1 CTRP2 6.093 10.7917 2.8848 6.4653
NCI-H2052 CTRP2 6.3162 14.8784 1.0414 13.3549
JL-1 CTRP2 7.2173 8.6761 4.4365 0.1344
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP2; CTRP1 3.9179 5.0316 3.7939 7.1146
22Rv1 CTRP2 3.9915 5.9616 3.5049 7.9458
LNCaP clone FGC CTRP2 4.2738 5.463 4.0124 5.1984
DU145 CTRP2 4.3883 6.8044 3.4976 7.0153
VCaP CTRP2 5.0933 7.7144 3.6553 4.9175
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 6.1145 8.2256 4.1131 1.6046
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1 CTRP2 1.4659 2.4882 1.4653 22.9528
MKN1 CTRP2 1.6654 3.4083 1.6392 21.7083
ECC10 CTRP2 1.937 3.4791 1.9169 19.8762
HGC-27 CTRP2 1.972 2.8218 1.9716 19.5764
SNU-16 CTRP2 2.4419 3.2394 2.441 16.444
GSS CTRP2 2.6263 3.9924 2.5953 15.3159
SNU-216 CTRP2 2.8251 3.8827 2.8125 13.9276
LMSU CTRP2 3.2763 4.0841 3.2677 10.9047
MKN7 CTRP2 3.3681 5.7685 2.9332 11.8574
MKN74 CTRP2; CTRP1 3.5104 6.5657 2.7515 12.2606
SNU-601 CTRP2 3.5166 5.0151 3.3587 9.8299
Hs 746.T CTRP2 3.8319 4.9903 3.7099 7.6001
HuG1-N CTRP2 3.8913 5.1593 3.7206 7.3848
SH-10-TC CTRP2 4.3242 8.7484 2.4812 11.3818
SNU-620 CTRP2 4.8294 5.9564 4.3162 2.6396
KATO III CTRP2 4.8463 6.1905 4.2139 3.0354
KE-39 CTRP2 4.8531 7.1513 3.7395 5.0173
NCI-N87 CTRP2 5.222 9.1357 3.049 7.2281
AGS CTRP2; CTRP1 5.226 6.2385 4.4948 1.2746
GSU CTRP2 5.6805 6.4027 4.6638 0.199
ECC12 CTRP2 5.7907 7.3492 4.32 1.1959
MKN45 CTRP2 6.1188 7.2822 4.5137 0.3411
SNU-668 CTRP2 6.8412 8.2191 4.4581 0.1871
NUGC-3 CTRP2 6.9466 11.6594 3.0413 4.6684
IM95 CTRP2 7.0054 8.8402 4.2949 0.4339
23132/87 CTRP2 7.1036 8.3334 4.5134 0.073
NUGC-4 CTRP2 7.112 9.1597 4.2182 0.5576
SNU-719 CTRP2 7.156 8.9175 4.3273 0.314
SNU-5 CTRP2 7.1889 15.7156 1.266 11.1336
SNG-M CTRP2; CTRP1 3.4405 4.1978 3.4312 9.8886
SNU-1077 CTRP2 5.1025 8.4296 3.3058 6.3685
SNU-685 CTRP2 6.2218 10.5459 3.0937 5.4291
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
B-CPAP CTRP2 1.4905 1.9768 1.4905 22.7869
FTC-238 CTRP2 2.6819 3.8724 2.6643 14.8993
FTC-133 CTRP2 3.4647 5.4673 3.1509 10.7551
TT2609-C02 CTRP2 4.3531 5.0258 4.2664 4.0032
8305C CTRP2 4.4364 7.6814 3.1104 8.5205
SW579 CTRP2 4.5137 4.8755 4.486 2.7188
CGTH-W-1 CTRP2 5.1731 7.2123 3.9678 3.4663
ML-1 [Human leukemia] CTRP2 6.0075 8.4258 3.9582 2.2996
8505C CTRP2 6.0728 9.8353 3.3336 4.6769
CAL-62 CTRP2 6.5125 7.7794 4.4897 0.2304
BHT-101 CTRP2 6.8731 8.3076 4.4385 0.2092
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-25 CTRP2 1.2388 4.9332 0.8966 25.6512
HSC-4 CTRP2 1.631 3.1863 1.6173 21.8952
HSC-2 CTRP2 1.8367 2.5769 1.8366 20.4778
SCC-4 CTRP2 2.1265 2.9988 2.1258 18.547
HSC-3 CTRP2 2.6911 5.1328 2.4235 15.7248
PE/CA-PJ49 CTRP2 2.8498 4.3953 2.7781 13.9654
PE/CA-PJ34 (clone C12) CTRP2 3.4102 4.9143 3.2715 10.4684
YD-8 CTRP2 3.4261 5.9442 2.9243 11.7319
FaDu CTRP2 3.5629 5.0199 3.4078 9.5118
CAL-33 CTRP2 3.7879 4.9051 3.6862 7.8193
BICR 6 CTRP2 3.9932 5.2555 3.7968 6.8048
PE/CA-PJ15 CTRP2 4.3257 4.9938 4.2469 4.1563
BICR 56 CTRP2 4.4517 5.3168 4.2595 3.7547
PE/CA-PJ41 (clone D2) CTRP2 4.8893 6.257 4.2172 2.9366
SCC-9 CTRP2; CTRP1 4.9259 6.3202 4.2247 2.9104
SNU-1214 CTRP2 5.1283 8.6083 3.2373 6.6089
SNU-1076 CTRP2 5.3842 8.6048 3.4391 5.3133
CAL-27 CTRP2 5.6265 7.9573 3.9317 2.9039
SNU-46 CTRP2 5.6968 7.979 3.9688 2.6569
BICR 22 CTRP2 5.8267 7.3071 4.359 1.0217
BICR 16 CTRP2 5.9996 8.7981 3.7792 3.003
BICR 31 CTRP2 6.0035 8.8877 3.7394 3.1542
BICR 18 CTRP2 6.1994 8.4563 4.0585 1.7133
SNU-1066 CTRP2 6.5316 11.6177 2.7899 6.2034
YD-10B CTRP2 6.7081 8.2773 4.3838 0.3678
SNU-899 CTRP2 6.9202 9.8107 3.8599 1.719
SNU-1041 CTRP2 7.0199 12.6891 2.6045 6.2631
Detroit 562 CTRP2 7.315 9.4434 4.1959 0.5166
BHY CTRP2 9.7761 27.8706 -2.8137 19.4844
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 1.87 3.0226 1.8667 20.2664
KMBC-2 CTRP2 2.3889 3.4645 2.3833 16.8132
HT-1197 CTRP2 2.4349 4.1898 2.3657 16.7235
UM-UC-3 CTRP2 2.6489 4.0106 2.6173 15.1669
HT-1376 CTRP2 2.8949 5.4416 2.5449 14.6746
T24 CTRP2 3.0316 4.4129 2.9709 12.7152
U-BLC1 CTRP2 3.0354 3.96 3.0257 12.5149
VM-CUB-1 CTRP2 3.2745 5.1115 3.0656 11.6275
SW1710 CTRP2 3.4393 5.4888 3.1157 10.961
TCCSUP CTRP2 3.5036 6.0681 2.9543 11.4052
639V CTRP2 3.5512 3.9593 3.551 9.0429
5637 CTRP2 3.7058 6.6081 2.9253 10.9926
SCaBER CTRP2 3.7119 6.2008 3.1132 10.2275
RT-112 CTRP2 3.9175 6.1027 3.3669 8.6863
KU-19-19 CTRP2 4.4108 5.7884 4.0063 4.8718
BC-3C CTRP2 4.5479 5.1284 4.4384 2.7971
UM-UC-1 CTRP2 4.681 5.4027 4.4525 2.3988
253J CTRP2 5.0349 6.8537 4.038 3.4166
CAL-29 CTRP2 5.0401 6.8136 4.0622 3.3055
BFTC-905 CTRP2 5.755 8.3118 3.8489 3.0555
647V CTRP2 6.0959 8.1883 4.1191 1.6023
253J-BV CTRP2 6.1575 7.9307 4.2661 1.0363
J82 CTRP2 7.5115 10.3215 3.9396 1.046
RT-4 CTRP2 7.808 16.5596 1.285 10.1676
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 6.363 7.2707 4.6145 0.08

References

1 A novel metal-chelating inhibitor of protein farnesyltransferase. Bioorg Med Chem Lett. 2003 May 5;13(9):1523-6.
2 Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation. Free Radic Biol Med. 2009 Aug 15;47(4):364-74.
3 Selective cytotoxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells: potential involvement of H-Ras downregulation. Toxicol Lett. 2010 Feb 15;192(3):425-30. doi: 10.1016/j.toxlet.2009.11.021. Epub 2009 Dec 1.
4 Involvement of H-Ras and reactive oxygen species in proinflammatory cytokine-induced matrix metalloproteinase-13 expression in human articular chondrocytes. Arch Biochem Biophys. 2011 Mar 15;507(2):350-5. doi: 10.1016/j.abb.2010.12.032. Epub 2011 Jan 3.
5 Expression of rTSbeta as a 5-fluorouracil resistance marker in patients with primary breast cancer. Oncol Rep. 2008 Apr;19(4):881-8.
6 Proteomic identification of heat shock protein 70 as a candidate target for enhancing apoptosis induced by farnesyl transferase inhibitor. Proteomics. 2003 Oct;3(10):1904-11. doi: 10.1002/pmic.200300547.