Details of the Drug

General Information of Drug (ID: DM1V78I)

Drug Name
MK-6096
Synonyms
FILOREXANT; MK-6096; 1088991-73-4; UNII-E6BTT8VA5Z; MK6096; MK 6096; E6BTT8VA5Z; ((2R,5R)-5-(((5-Fluoropyridin-2-yl)oxy)methyl)-2-methylpiperidin-1-yl)(5-methyl-2-(pyrimidin-2-yl)phenyl)methanone; Methanone, [(2R,5R)-5-[[(5-fluoro-2-pyridinyl)oxy]methyl]-2-methyl-1-piperidinyl][5-methyl-2-(2-pyrimidinyl)phenyl]-; Methanone, ((2R,5R)-5-(((5-fluoro-2-pyridinyl)oxy)methyl)-2-methyl-1-piperidinyl)(5-methyl-2-(2-pyrimidinyl)phenyl)-; Filorexant [USAN:INN]; Filorexant (USAN); Filorexant(mk-6096); MK-6096; Filorexant; GTPL4460
Indication
Disease Entry ICD 11 Status REF
Diabetic neuropathy 8C0Z Phase 2 [1]
Insomnia 7A00-7A0Z Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C24H25FN4O2
Canonical SMILES
CC1CCC(CN1C(=O)C2=C(C=CC(=C2)C)C3=NC=CC=N3)COC4=NC=C(C=C4)F
InChI
InChI=1S/C24H25FN4O2/c1-16-4-8-20(23-26-10-3-11-27-23)21(12-16)24(30)29-14-18(6-5-17(29)2)15-31-22-9-7-19(25)13-28-22/h3-4,7-13,17-18H,5-6,14-15H2,1-2H3/t17-,18-/m1/s1
InChIKey
NPFDWHQSDBWQLH-QZTJIDSGSA-N
Cross-matching ID
PubChem CID
25128145
ChEBI ID
CHEMBL2107822
CAS Number
1088991-73-4
UNII
E6BTT8VA5Z
DrugBank ID
DB12158
TTD ID
D0NN5A
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References

1 ClinicalTrials.gov (NCT01021852) Polysomnography Study of MK6096 in Patients With Primary Insomnia (6096-011). U.S. National Institutes of Health.