Details of the Drug

General Information of Drug (ID: DM1Z5W8)

Drug Name
ISIS 147788
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Antisense drug
Sequence
TTTCTGTTGCCACATTGCCC
Cross-matching ID
TTD ID
D09YRP

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
APOB messenger RNA (APOB mRNA) TTN1IE2 APOB_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
APOB messenger RNA (APOB mRNA) DTT APOB 9.53E-01 0.03 0.18
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 US patent application no. 7,407,943, Antisense modulation of apolipoprotein B expression.