Details of the Drug

General Information of Drug (ID: DM295IJ)

• Drug Name: AR101
• Synonyms: 5-[[(2R)-2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine; (R)-Iclaprim; CHEMBL1236788; 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine; 5-{[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl}pyrimidine-2,4-diamine; SCHEMBL20138534; CHEBI:131752; XCF; ZINC3612862; BDBM50336513; DB08741; UNII-42445HUU0O component HWJPWWYTGBZDEG-AWEZNQCLSA-N

Indication

Disease Entry	ICD 11	Status	REF
Allergy	4A80-4A85	Phase 3	[1]

• Chemical Identifiers:
  Formula: C19H22N4O3
  Canonical SMILES: COC1=C(C2=C(C=CC(O2)C3CC3)C(=C1)CC4=CN=C(N=C4N)N)OC
  InChI: InChI=1S/C19H22N4O3/c1-24-15-8-11(7-12-9-22-19(21)23-18(12)20)13-5-6-14(10-3-4-10)26-16(13)17(15)25-2/h5-6,8-10,14H,3-4,7H2,1-2H3,(H4,20,21,22,23)/t14-/m0/s1
  InChIKey: HWJPWWYTGBZDEG-AWEZNQCLSA-N
• Cross-matching ID:
  PubChem CID: 10247560
  ChEBI ID: CHEMBL131752
  UNII: RG4NWL6NKS
  DrugBank ID: DB08741
  TTD ID: D0O8TJ
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)