Details of the Drug

General Information of Drug (ID: DM2AYUX)

• Drug Name: CC-100
• Synonyms: Fendosal; 53597-27-6; 5-(4,5-Dihydro-2-phenyl-3H-benz[e]indol-3-yl)salicylic acid; Alnovin; Fendosalum; HP 129; Fendosalum [INN-Latin]; UNII-9Z709558TZ; P 71-0129; C25H19NO3; NSC 351522; BRN 1665211; 2-hydroxy-5-(2-phenyl-4,5-dihydrobenzo[e]indol-3-yl)benzoic acid; 2-Hydroxy-5-(2-phenyl-4,5-dihydro-3H-benzo[e]indol-3-yl)benzoic acid; 3-(3-Carboxy-4-hydroxyphenyl)-2-phenyl-4,5-dihydro-3H-benz(e)indole; 5-(4,5-Dihydro-2-phenyl-3H-benz(e)indol-3-yl)-2-hydroxybenzoic acid; NSC351522; HP-129; 9Z709558TZ

Indication

Disease Entry	ICD 11	Status	REF
Amyotrophic lateral sclerosis	8B60.0	Phase 1	[1]
Motor neurone disease	8B60	Phase 1	[2]

• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C25H19NO3
  Canonical SMILES: C1CC2=C(C=C(N2C3=CC(=C(C=C3)O)C(=O)O)C4=CC=CC=C4)C5=CC=CC=C51
  InChI: InChI=1S/C25H19NO3/c27-24-13-11-18(14-21(24)25(28)29)26-22-12-10-16-6-4-5-9-19(16)20(22)15-23(26)17-7-2-1-3-8-17/h1-9,11,13-15,27H,10,12H2,(H,28,29)
  InChIKey: HAWWPSYXSLJRBO-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 40821
  ChEBI ID: CHEMBL135595
  CAS Number: 53597-27-6
  TTD ID: D0UU1E
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] ClinicalTrials.gov (NCT02050334) CC100: Safety and Tolerability of Single Doses. U.S. National Institutes of Health.