Details of the Drug

General Information of Drug (ID: DM2V45Z)

Drug Name
3-fluoro-5-(2-methylquinolin-7-yl)benzonitrile
Synonyms 3-Fluoro-5-(2-methylquinolin-7-yl)benzonitrile; CHEMBL232188; GTPL6444; SCHEMBL4303163; BDBM50216746; compound 23 [PMID:; compound 23
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 262.28
Logarithm of the Partition Coefficient (xlogp) 4
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C17H11FN2
IUPAC Name
3-fluoro-5-(2-methylquinolin-7-yl)benzonitrile
Canonical SMILES
CC1=NC2=C(C=C1)C=CC(=C2)C3=CC(=CC(=C3)C#N)F
InChI
InChI=1S/C17H11FN2/c1-11-2-3-13-4-5-14(9-17(13)20-11)15-6-12(10-19)7-16(18)8-15/h2-9H,1H3
InChIKey
SDOLISUYGVMVBK-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
23661671
TTD ID
D0S1CS

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Metabotropic glutamate receptor 5 (mGluR5) TTHS256 GRM5_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Metabotropic glutamate receptor 5 (mGluR5) DTT GRM5 9.81E-07 -0.26 -0.54
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 139 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 1.5193 4.0791 1.4114 23.8519
MEC1 CTRP2 2.3076 4.0596 2.2576 18.4022
HuT 78 CTRP2 -1.0855 11.7291 -4.1773 44.8196
MV4-11 CTRP2 0.0651 1.9315 0.0603 33.1885
NALM-6 CTRP2 0.2547 2.2909 0.2442 31.9446
EoL-1 CTRP2 0.2797 1.0825 0.2797 31.7433
MOLM-13 CTRP2 0.4675 1.9169 0.4662 30.4962
SUP-M2 CTRP2 0.6991 1.2417 0.6991 28.9491
Ki-JK CTRP2 0.7691 2.2495 0.7667 28.4905
697 CTRP2 0.8046 1.7248 0.8046 28.2461
Peer CTRP2 1.0103 2.5179 1.0065 26.8885
NU-DUL-1 CTRP2; CTRP1 1.0252 2.4445 1.0227 26.8551
MOLT-3 CTRP2 1.1605 1.8915 1.1605 25.8753
OCI-AML-3 CTRP2; CTRP1 1.2656 2.7022 1.2616 25.2604
SEM CTRP2 1.2785 2.2515 1.2784 25.0893
Kasumi-2 CTRP2 1.2885 2.0019 1.2885 25.0225
Pfeiffer CTRP2 1.3135 2.4253 1.3128 24.8582
CML-T1 CTRP2 1.3783 2.5223 1.3774 24.4273
GA-10 CTRP2 1.4095 2.9909 1.4004 24.2466
KM-H2 CTRP2 1.433 2.3129 1.4329 24.0601
Ku812 CTRP2; CTRP1 1.4649 3.5171 1.4259 24.0517
PF-382 CTRP2 1.4956 4.0089 1.3972 23.9771
KMS-34 CTRP2 1.5135 2.0978 1.5135 23.5236
RPMI-8402 CTRP2 1.5162 2.4311 1.516 23.506
JVM-3 CTRP2 1.5236 3.6148 1.4777 23.6108
MOLT-16 CTRP2 1.5537 2.0622 1.5537 23.2554
ALL-SIL CTRP2 1.5557 2.4243 1.5555 23.2429
KE-37 CTRP2 1.5596 2.9006 1.5555 23.2299
OCI-AML-2 CTRP2 1.5792 1.9809 1.5792 23.0856
KMS-12-BM CTRP2 1.5896 2.1835 1.5896 23.0162
P12-Ichikawa CTRP2 1.5979 2.8983 1.5944 22.9729
Granta-519 CTRP2 1.5982 4.052 1.5005 23.2912
MOLT-13 CTRP2 1.6132 3.3106 1.5953 22.919
AML-193 CTRP2 1.6182 3.5031 1.5872 22.9299
NCI-H929 CTRP2 1.6188 4.6585 1.4038 23.5635
RS4;11 CTRP2 1.6277 2.3841 1.6277 22.7626
KO52 CTRP2 1.6357 3.6273 1.5945 22.8478
SU-DHL-10 CTRP2 1.6477 2.2339 1.6477 22.6292
NU-DHL-1 CTRP2 1.6492 2.45 1.6491 22.6198
HDLM-2 CTRP2 1.6523 4.7302 1.4234 23.39
OCI-Ly3 CTRP2 1.6601 3.5606 1.6262 22.6605
JJN-3 CTRP2 1.7095 3.2624 1.697 22.2594
SU-DHL-1 CTRP2 1.7098 2.1312 1.7098 22.2156
A4/Fukuda CTRP2 1.7293 3.187 1.7204 22.1151
EB1 CTRP2 1.7511 3.5363 1.7234 22.0333
BV-173 CTRP2 1.7595 4.334 1.6255 22.3433
Jurkat CTRP2 1.7665 3.263 1.7555 21.8746
KHM-1B CTRP2 1.7891 3.3375 1.7753 21.7335
KMS-26 CTRP2 1.8364 3.289 1.8262 21.4061
KMS-21-BM CTRP2 1.8489 3.6009 1.8204 21.3845
Karpas-299 CTRP2 1.8545 4.0883 1.7699 21.5393
NB4 CTRP2 1.8598 4.0011 1.7883 21.4586
JURL-MK1 CTRP2 1.8603 3.756 1.8183 21.3543
SU-DHL-8 CTRP2 1.8651 5.6476 1.3931 22.8487
SIG-M5 CTRP2 1.8658 3.1098 1.8617 21.19
HuNS1 CTRP2 1.9038 4.4913 1.7505 21.45
SUP-T1 CTRP2 2.0423 4.1803 1.9572 20.29
MHH-CALL-4 CTRP2 2.0552 8.6106 0.4124 25.7803
NOMO-1 CTRP1 2.078 4.7036 1.8954 43.3573
M-07e CTRP2 2.0836 4.3321 1.976 20.0931
AMO1 CTRP2; CTRP1 2.0841 3.514 2.0707 19.8441
LAMA-84 CTRP2 2.2035 4.3458 2.103 19.2698
SUP-HD1 CTRP2 2.2441 4.6139 2.0942 19.1725
TALL-1 [Human adult T-ALL] CTRP2 2.2445 4.0571 2.1909 18.8348
Ri-1 CTRP2 2.2859 4.775 2.103 19.011
WSU-DLCL2 CTRP2; CTRP1 2.3189 3.2832 2.3172 18.2424
EHEB CTRP2 2.3543 4.7547 2.1824 18.5166
SK-MM-2 CTRP2 2.3571 5.4668 1.9863 19.2176
GDM-1 CTRP2; CTRP1 2.3621 4.2641 2.2885 18.1989
F-36P CTRP2 2.375 5.2786 2.064 18.8798
HEL CTRP2 2.4126 4.5256 2.2954 17.9359
PL21 CTRP2; CTRP1 2.4773 4.6226 2.3475 17.6284
KMS-28BM CTRP2 2.4828 4.9027 2.2862 17.7499
U266B1 CTRP2 2.5117 5.1075 2.2629 17.7454
KMS-11 CTRP2; CTRP1 2.5209 4.6514 2.3888 17.3468
THP-1 CTRP2; CTRP1 2.5658 4.1112 2.5263 16.7263
BL-70 CTRP2; CTRP1 2.5747 3.97 2.5498 16.6178
RCH-ACV CTRP2 2.661 4.8534 2.4929 16.4621
SR CTRP2 2.6682 5.2591 2.3895 16.8133
KE-97 CTRP2; CTRP1 2.6827 3.9017 2.6676 15.8661
SU-DHL-6 CTRP2 2.6829 4.9484 2.4927 16.3953
P31/FUJ CTRP2 2.7214 4.9536 2.5335 16.1308
Hs 611.T CTRP2 2.7423 4.4044 2.6734 15.5714
ME1 CTRP2 2.7455 4.5607 2.6491 15.6458
EM-2 CTRP2 2.7631 4.5587 2.6686 15.5222
SKM-1 CTRP2; CTRP1 2.773 4.5585 2.6809 15.5292
Mono-Mac-6 CTRP2 2.8122 7.385 1.7272 18.9214
KCL-22 CTRP2 2.8213 5.0172 2.6256 15.4944
MOLM-6 CTRP2 2.8282 5.4189 2.5141 15.88
KMS-20 CTRP2 2.8598 4.2797 2.8173 14.6978
LP-1 CTRP2; CTRP1 2.8885 4.1225 2.8654 14.523
CA46 CTRP2 2.9375 5.1156 2.7253 14.7809
HT CTRP2; CTRP1 2.9448 3.6952 2.9435 14.075
Mono-Mac-1 CTRP2 2.9982 5.3643 2.7164 14.632
OCI-AML-5 CTRP2 3.0142 4.7169 2.9088 13.8885
L-540 CTRP2 3.0157 4.5042 2.9511 13.7358
MC116 CTRP2; CTRP1 3.0202 4.4147 2.971 13.7358
OPM-2 CTRP2 3.0631 4.9863 2.8977 13.7764
SUP-T11 CTRP2 3.1248 4.6528 3.042 13.0727
K-562 CTRP2 3.1534 4.8719 3.0251 13.043
L-363 CTRP2 3.158 6.287 2.5508 14.8032
SU-DHL-5 CTRP1 3.1597 4.1074 3.1492 27.2068
U-937 CTRP2; CTRP1 3.1625 5.1691 2.9582 13.3395
JVM-2 CTRP2 3.163 5.0055 3.0017 13.0973
Namalwa CTRP2 3.205 5.2956 2.9632 13.1109
Kasumi-1 CTRP2 3.2541 4.9343 3.1195 12.3952
SU-DHL-4 CTRP2; CTRP1 3.26 5.502 2.9591 13.0478
L-428 CTRP2 3.2877 4.9684 3.1475 12.1919
MM1.S CTRP2 3.313 5.1187 3.134 12.1634
RPMI-8226 CTRP2; CTRP1 3.377 4.4366 3.3484 11.2905
HPB-ALL CTRP2 3.4117 6.0174 2.9271 12.6553
OCI-Ly19 CTRP2 3.4133 6.28 2.8223 13.056
MOLP-8 CTRP2 3.4195 5.3016 3.1948 11.6226
KMS-27 CTRP2 3.4313 5.1768 3.2461 11.3997
DEL CTRP2 3.5007 4.5174 3.4689 10.3924
KMS-18 CTRP2 3.6853 6.3717 3.067 11.3716
MOLP-2 CTRP2 3.7811 7.6702 2.5723 13.1125
MOLM-16 CTRP2; CTRP1 3.7827 5.8558 3.3894 9.9382
DND-41 CTRP2 3.9444 5.8769 3.5462 8.8033
A3/Kawakami CTRP2 4.0619 4.9676 3.9921 6.7879
MHH-CALL-3 CTRP2 4.0674 9.1703 2.1197 14.2824
RPMI-6666 CTRP2 4.1261 5.1695 4.0054 6.5453
TF-1 CTRP2 4.1716 5.1432 4.0632 6.1977
KYO-1 CTRP2 4.1744 5.6215 3.8927 6.8338
HL-60 CTRP2 4.1748 6.0107 3.7283 7.4769
HEL 92.1.7 CTRP2 4.1783 7.2998 3.133 9.8781
EJM CTRP2; CTRP1 4.2226 6.2136 3.6926 7.5843
HD-MY-Z CTRP2 4.2484 5.0815 4.1653 5.5948
OCI-M1 CTRP2 4.2689 5.1392 4.1704 5.5146
CMK CTRP2 4.3442 4.8896 4.3163 4.7604
Karpas-422 CTRP2 4.3744 4.9001 4.3469 4.5578
P3HR-1 CTRP2; CTRP1 4.5039 8.9453 2.6358 11.2881
Reh CTRP2 4.5128 10.6065 1.8088 14.563
Raji CTRP2 4.569 5.0629 4.5204 3.3376
REC-1 CTRP2 4.6414 5.5901 4.3908 3.639
OCI-Ly10 CTRP2; CTRP1 4.6862 8.2192 3.1583 8.7288
RL CTRP2 4.7671 8.774 2.9437 9.3764
Karpas-620 CTRP2 4.9589 5.9075 4.5397 2.2925
Toledo CTRP2 6.8784 18.7256 -0.3344 17.7606
⏷ Show the Full List of 139 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 3.404 11.3229 0.4515 22.1428
TE15 CTRP2 3.9953 6.6262 3.2699 9.7662
OE21 CTRP2 1.8262 4.0859 1.74 21.7331
KYSE-140 CTRP2; CTRP1 3.0401 4.5129 2.9771 13.651
TE-5 CTRP2 3.2408 5.7263 2.8552 13.4091
TE-10 CTRP2 3.2762 5.7999 2.8662 13.2665
KYSE-450 CTRP2; CTRP1 3.2979 3.9463 3.2964 11.7254
KYSE-180 CTRP2 3.369 5.6794 3.0103 12.4578
KYSE-410 CTRP2; CTRP1 3.3868 4.9091 3.2727 11.5245
OE33 CTRP2 3.4715 6.2602 2.8916 12.6293
KYSE-70 CTRP2 3.5533 5.576 3.2463 11.0415
TE-4 CTRP2 3.6444 6.5128 2.9637 11.8864
TE-14 CTRP2 3.6748 7.2201 2.6771 12.9514
TE-1 CTRP2 3.7415 7.3167 2.6988 12.6982
TE-9 CTRP2 3.9115 5.0787 3.7985 7.9439
KYSE-510 CTRP2 4.0137 6.5163 3.3384 9.4446
KYSE-520 CTRP2 4.1193 6.9932 3.2219 9.6553
COLO 680N CTRP2 4.1466 5.4564 3.9278 6.7766
TE-11 CTRP2 4.3673 5.1915 4.2607 4.8911
EC-GI-10 CTRP2 4.4915 5.6687 4.2033 4.7712
KYSE-150 CTRP2 4.7569 5.2698 4.6495 2.3138
KYSE-30 CTRP2 4.8758 9.077 2.886 9.3978
OE19 CTRP2 4.9214 6.0531 4.4342 2.8125
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.1824 6.2318 3.6374 7.8197
BxPC-3 CTRP2 2.2537 4.8398 2.0521 19.292
Capan-2 CTRP2; CTRP1 2.5406 4.1842 2.4907 16.93
PaTu 8902 CTRP2; CTRP1 2.7151 3.9469 2.6982 15.6564
PK-59 CTRP2 2.8357 5.868 2.3678 16.4039
QGP-1 CTRP2; CTRP1 3.1233 4.45 3.0762 13.0426
KP-3 CTRP2; CTRP1 3.17 5.8453 2.7397 14.1292
PaTu 8988s CTRP2 3.2871 5.9646 2.8152 13.4302
SUIT-2 CTRP2; CTRP1 3.2988 5.3435 3.0534 12.5849
HuP-T4 CTRP2; CTRP1 3.3169 4.5108 3.2746 11.7378
SNU-213 CTRP2 3.4568 5.4624 3.182 11.5608
Panc 05.04 CTRP2 3.4807 5.4759 3.2032 11.4125
Panc 10.05 CTRP1 3.5154 4.9919 3.3922 22.9652
HPAC CTRP2; CTRP1 3.5252 4.9541 3.4125 10.5992
Panc 03.27 CTRP2; CTRP1 3.5471 4.24 3.5419 10.0793
Capan-1 CTRP2 3.6995 8.3592 2.1661 14.9492
CFPAC-1 CTRP2; CTRP1 3.7457 5.5291 3.4746 9.7175
TCC-Pan2 CTRP2 3.7507 6.0806 3.2587 10.4459
MIA PaCa-2 CTRP2 3.7718 5.8058 3.3929 9.8684
Hs 766T CTRP2 3.8251 5.8792 3.4198 9.6183
PK-45H CTRP2 3.8294 6.7827 3.032 11.1385
Panc 08.13 CTRP2 3.8842 6.3078 3.2999 9.9306
AsPC-1 CTRP2 3.9053 5.8443 3.5185 9.0176
HPAF-II CTRP2 4.0039 7.0508 3.0818 10.5046
YAPC CTRP2 4.1591 6.4503 3.5144 8.3723
KP-4 CTRP2 4.186 5.834 3.8165 7.0999
SW1990 CTRP2 4.3022 6.5417 3.6133 7.6198
PSN1 CTRP2 4.3623 8.7703 2.5864 11.7179
SU.86.86 CTRP2 4.3702 19.6491 -2.8271 28.8626
HuP-T3 CTRP2 4.3886 5.1933 4.2831 4.7455
DAN-G CTRP2 4.4592 5.2125 4.3531 4.2795
Panc 04.03 CTRP2 4.5086 5.0957 4.4449 3.7944
Panc 02.03 CTRP2 4.5364 5.1098 4.4709 3.616
L3.3 CTRP2 4.5379 4.9199 4.52 3.4353
KP-2 CTRP2 4.5437 4.9345 4.5236 3.4045
PaTu 8988t CTRP2 4.6119 4.9812 4.588 2.964
SNU-410 CTRP2 6.5918 20.0804 -1.2261 20.8504
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 1.61 3.0281 1.6038 22.9011
LOX-IMVI CTRP2 1.8399 6.0715 1.2213 23.5465
A101D CTRP2 2.0321 3.5965 2.0117 20.137
UACC-257 CTRP2 2.2516 3.8185 2.2238 18.6995
Mel Ho CTRP2 2.31 3.8712 2.2803 18.317
G-361 CTRP2; CTRP1 2.8601 4.19 2.829 14.7393
Hs 852.T CTRP2; CTRP1 2.8972 3.946 2.887 14.4214
RPMI-7951 CTRP2 3.2252 4.8705 3.1036 12.5412
A-375 CTRP2; CTRP1 3.2891 4.5224 3.243 11.9356
Hs 936.T CTRP2; CTRP1 3.2955 3.8245 3.2952 11.7376
COLO 800 CTRP2 3.4935 5.8141 3.0934 11.7903
Hs 944.T CTRP2; CTRP1 3.4938 4.4494 3.4706 10.495
COLO 741 CTRP2; CTRP1 3.5769 4.9748 3.4637 10.257
SK-MEL-24 CTRP2 3.596 4.373 3.5844 9.6883
WM793 CTRP2 4.0093 5.5219 3.756 7.8168
COLO 792 CTRP2 4.0544 5.4428 3.8339 7.3938
MeWo CTRP2 4.0565 4.9866 3.9815 6.8425
IGR-37 CTRP2 4.0728 5.0274 3.9886 6.7668
SK-MEL-5 CTRP2; CTRP1 4.0961 4.878 4.0515 6.561
Hs 294T CTRP2 4.1421 5.0907 4.0466 6.3469
SK-MEL-3 CTRP2 4.1762 6.0052 3.7322 7.458
K029AX CTRP2 4.2113 6.9707 3.322 9.0261
Mel JuSo CTRP2 4.2177 8.6781 2.4997 12.3941
SK-MEL-30 CTRP2 4.2335 5.0714 4.1519 5.6888
WM983B CTRP2 4.2733 8.0566 2.8557 10.8021
SK-MEL-2 CTRP2 4.2825 5.3703 4.1057 5.7171
Hs 688(A).T CTRP2 4.3106 5.3084 4.1586 5.4371
SK-MEL-1 CTRP2; CTRP1 4.3175 4.9218 4.2827 5.0541
IGR-1 CTRP2 4.3341 5.6638 4.0428 5.8182
UACC-62 CTRP2 4.3425 4.8139 4.3268 4.7295
WM1799 CTRP2 4.3566 4.9105 4.3256 4.6887
HT-144 CTRP2 4.3627 4.9866 4.3154 4.7055
MDA-MB-435S CTRP2 4.3744 5.0025 4.3242 4.638
WM88 CTRP2 4.3819 5.3542 4.2182 5.0091
IGR-39 CTRP2 4.3824 4.9219 4.3513 4.5172
IPC-298 CTRP2 4.3936 4.951 4.3574 4.4606
A2058 CTRP2 4.4153 4.9308 4.3852 4.2948
WM115 CTRP2 4.4579 4.8919 4.4386 3.9733
Hs 895.T CTRP2 4.4599 4.9123 4.4371 3.972
WM266-4 CTRP2 4.4727 4.8328 4.463 3.8414
COLO 829 CTRP2 4.4814 5.1629 4.394 4.0623
RVH-421 CTRP2 4.5374 4.96 4.5116 3.4666
HMCB CTRP2 4.5426 4.8661 4.5332 3.3747
Hs 839.T CTRP2 4.5543 5.1838 4.4659 3.5823
SK-MEL-31 CTRP2 4.7496 5.3498 4.608 2.4961
SK-MEL-28 CTRP2; CTRP1 4.7703 6.0616 4.3006 3.7884
WT2-iPS CTRP2 4.7706 5.3347 4.6361 2.33
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 3.5035 5.598 3.1847 11.4162
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 CTRP2 1.3739 2.4786 1.3732 24.4559
IMR-32 CTRP2 1.8789 3.3573 1.8668 21.1292
SK-N-FI CTRP2 2.7751 5.0841 2.5569 15.8827
SK-N-SH CTRP2 2.9599 4.8381 2.8224 14.3638
KP-N-SI9s CTRP2 3.1756 4.7472 3.0777 12.7876
Kelly CTRP2 3.2023 4.6856 3.1194 12.5567
SK-N-BE(2) CTRP2 3.3398 5.9285 2.8853 13.0152
NH-6 CTRP2 3.4459 6.6977 2.6788 13.5309
CHP-212 CTRP2 3.4556 4.7251 3.386 10.8235
NB1 CTRP2 3.8954 6.3815 3.2788 9.9852
SK-N-AS CTRP2 3.9986 5.4056 3.7875 7.728
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 1.7321 3.3071 1.7181 22.1137
SNU-478 CTRP2 2.2657 4.3969 2.161 18.8699
SNU-308 CTRP2 3.4718 5.7069 3.1107 11.7859
HuH-28 CTRP2 3.6726 5.3432 3.4562 9.9111
SNU-1196 CTRP2 3.7075 5.4973 3.4407 9.8676
HuCC-T1 CTRP2 3.7994 5.409 3.5711 9.1137
SNU-869 CTRP2 4.2704 6.4117 3.6429 7.5775
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-MC CTRP2 1.8268 2.3076 1.8268 21.4363
MHH-ES-1 CTRP2 2.1118 3.7967 2.079 19.6476
Hs 888.T CTRP2 2.3983 16.079 -2.8081 33.1601
A-673 CTRP2 3.1936 4.5919 3.1277 12.5553
SK-ES-1 CTRP2 3.3301 5.4452 3.0505 12.4196
SW1353 CTRP2 3.7996 7.7938 2.5319 13.2314
SJSA-1 CTRP2 3.8599 12.363 0.3565 21.4032
U2OS CTRP2; CTRP1 3.891 6.136 3.387 9.6551
Hs 822.T CTRP2 4.2338 5.9189 3.8291 6.924
MG-63 CTRP2 4.2839 5.4236 4.087 5.7845
HOS CTRP2 4.394 4.8858 4.3708 4.4123
SaOS-2 CTRP2 4.4179 5.2742 4.2865 4.6482
G-292 clone A141B1 CTRP2 4.6428 6.8055 3.8102 6.0188
CAL-78 CTRP2 7.6659 18.7872 0.2163 14.7396
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 1.4376 2.1911 1.4376 24.0292
CAL-148 CTRP2 1.953 4.365 1.8289 21.0204
AU565 CTRP2 2.4631 4.2471 2.3982 17.4175
MCF-7 CTRP2; CTRP1 2.5173 5.6089 2.1177 18.3387
HCC1954 CTRP2 2.9153 4.9713 2.7404 14.7941
CAL-51 CTRP2 3.0111 5.4508 2.7024 14.6455
ZR-75-1 CTRP2 3.0531 5.701 2.6621 14.6738
HCC1806 CTRP2 3.1399 5.0758 2.9573 13.3279
EFM-192A CTRP2 3.2914 6.4088 2.6412 14.0897
HMC-1-8 CTRP2 3.4326 4.8941 3.324 11.1143
MDA-MB-453 CTRP2 3.618 6.0414 3.1356 11.2841
KPL-1 CTRP2 3.6523 12.9809 -0.1363 23.4994
HCC1143 CTRP2 3.7388 6.1664 3.2102 10.6675
JIMT-1 CTRP2 3.7692 4.9107 3.6868 8.7808
T-47D CTRP2 3.8491 7.5889 2.6771 12.523
MDA-MB-231 CTRP2 3.8812 6.4727 3.2239 10.2399
HCC1395 CTRP2 3.8889 6.1862 3.3576 9.6903
HCC2218 CTRP2 3.8892 7.6304 2.6964 12.3482
BT-474 CTRP2 4.1049 5.6981 3.7883 7.4277
MDA-MB-468 CTRP2 4.1344 5.8886 3.7395 7.5389
HCC1500 CTRP2 4.1389 5.8272 3.7704 7.4059
BT-20 CTRP2 4.3029 5.1574 4.2017 5.2989
CAMA-1 CTRP2 4.3043 5.8764 3.9201 6.38
HCC1428 CTRP2 4.3791 4.9078 4.3506 4.53
HCC202 CTRP2 4.4045 5.7457 4.0803 5.4848
HCC1937 CTRP2 4.4285 6.2513 3.8737 6.2546
MDA-MB-361 CTRP2 4.4376 5.2165 4.3283 4.4348
CAL-85-1 CTRP2 4.4503 6.4438 3.8039 6.487
BT-549 CTRP2 4.5198 6.0473 4.0589 5.28
HCC1419 CTRP2 4.5224 5.8603 4.1482 4.9125
ZR-75-30 CTRP2 4.8343 7.5345 3.6202 6.4046
HCC38 CTRP2 5.2667 9.8235 2.8375 8.8472
BT 416 CTRP2 1.1949 4.1945 1.0412 26.1697
BT 145 CTRP2 1.315 3.5273 1.2666 25.0085
BT 286 CTRP2 1.4645 2.2856 1.4644 23.85
BT147 CTRP2 1.814 4.4835 1.6548 22.0686
BT 239 CTRP2 1.8555 3.3298 1.8441 21.2831
BT 231 CTRP2 2.0706 4.7935 1.8639 20.5288
BT164 CTRP2 2.2105 4.7282 2.0319 19.4977
BT 440 CTRP2 2.6172 4.281 2.5582 16.3708
BT 248 CTRP2 2.7398 5.2518 2.4698 16.3059
BT 428 CTRP2 3.2257 5.2853 2.9889 12.955
BT 216 CTRP2 3.2612 5.1875 3.0575 12.5977
BT 228 CTRP2 3.4317 5.8255 3.023 12.2324
BT 172 CTRP2 3.4947 4.6418 3.4436 10.4985
BT 159 CTRP2 3.4973 5.1996 3.3112 10.9643
BT 359 CTRP2 3.5704 5.6769 3.2276 11.0634
BT 340 CTRP2 3.5878 5.5684 3.2861 10.7927
BT 139 CTRP2 3.6301 4.5408 3.6037 9.5115
BT 422 CTRP2 3.6759 5.5918 3.3724 10.2154
BT 245 CTRP2 3.7618 5.8004 3.3844 9.9288
BT 112 CTRP2 3.8413 6.984 2.9518 11.4311
BT 482 CTRP2 4.2239 5.1262 4.1253 5.8142
BT 224 CTRP2 4.2448 5.662 3.9502 6.4192
BT 179 CTRP2 4.2931 7.3851 3.2012 9.3306
BT 498 CTRP2 4.3527 4.9259 4.3183 4.7267
BT 328 CTRP2 4.4466 4.9668 4.4115 4.1038
BT 444 CTRP2 4.4495 4.9846 4.4105 4.0983
BT 320 CTRP2 4.7177 6.4159 4.0704 4.7713
BT 232 CTRP2 4.7748 6.8019 3.932 5.2234
BT 504 CTRP2 5.0619 10.8857 2.1383 12.1205
BT 333 CTRP2 5.2071 8.8885 3.2562 7.2069
BT 330 CTRP2 5.9304 9.7611 3.3774 5.4694
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.0544 4.7716 2.9406 13.6506
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 1.5734 2.5865 1.5729 23.1262
CAS-1 CTRP2 3.1856 5.6509 2.823 13.6886
LN-18 CTRP2 3.2534 4.1715 3.2421 11.9699
SF539 CTRP2 3.2843 4.9937 3.1371 12.2394
KNS-60 CTRP2 3.3327 13.8446 -0.8526 26.3825
GaMG CTRP2; CTRP1 3.3329 4.699 3.2599 11.7376
AM-38 CTRP2 3.5515 5.6378 3.2218 11.1389
A-172 CTRP2 3.5748 7.8518 2.2848 14.7749
ONS-76 CTRP2 3.607 5.4471 3.3498 10.4983
LN-229 CTRP2; CTRP1 3.6876 7.011 2.792 12.541
DBTRG-05MG CTRP2 3.7857 13.4157 -0.2315 23.492
SF268 CTRP2 3.811 5.5363 3.538 9.2052
SNU-466 CTRP2 3.9578 4.8281 3.9098 7.4039
NMC-G1 CTRP2 4.1069 4.9174 4.0529 6.432
SF295 CTRP2; CTRP1 4.1886 4.832 4.1601 5.8895
Hs 683 CTRP2 4.2114 5.1006 4.1194 5.8731
GOS-3 CTRP2 4.2408 7.5052 3.0935 9.8948
KG-1-C CTRP2 4.2917 5.1076 4.2049 5.3205
42-MG-BA CTRP2 4.3242 4.9685 4.2778 4.9586
GB-1 CTRP2 4.3515 5.2878 4.2101 5.1263
TM-31 CTRP2 4.3588 8.2993 2.8154 10.778
SW1088 CTRP2 4.3621 5.921 3.9593 6.0752
SNU-1105 CTRP2 4.3657 4.9426 4.3289 4.6485
M059K CTRP2 4.3836 6.0563 3.9196 6.1799
KNS-42 CTRP2 4.4059 7.744 3.1315 9.3632
U-251MG CTRP2 4.4295 4.9954 4.3861 4.2473
SNU-201 CTRP2 4.4449 5.1529 4.3575 4.3046
DK-MG CTRP2 4.4494 4.9313 4.4221 4.0577
GMS-10 CTRP2 4.4532 4.8507 4.4399 3.9837
U-118MG CTRP2 4.456 5.7443 4.1336 5.1398
SNB-75 CTRP2 4.4929 5.1678 4.4048 3.9888
YKG-1 CTRP2 4.501 4.9551 4.4732 3.7161
T98G CTRP2 4.5028 9.5567 2.3224 12.5034
U-87MG ATCC CTRP2 4.5049 7.169 3.5047 7.5944
SNU-626 CTRP2 4.513 5.0744 4.456 3.7404
SNU-489 CTRP2 4.5468 5.0488 4.5001 3.4784
Becker CTRP2 4.565 4.9665 4.5402 3.2794
YH-13 CTRP2 4.5716 5.8828 4.1868 4.6345
SW1783 CTRP2 4.656 5.573 4.4134 3.5115
SNU-738 CTRP2 5.0194 6.8064 4.1425 3.8393
SF126 CTRP2 5.0247 6.3586 4.3708 2.8695
8-MG-BA CTRP2 5.0715 6.1877 4.4951 2.257
Daoy CTRP2 5.6712 10.7068 2.7171 8.621
KNS-81 CTRP2 5.87 19.7021 -1.6083 23.151
KALS-1 CTRP2 6.3647 14.6554 1.2899 13.0798
CCF-STTG1 CTRP2 6.8415 13.0167 2.4383 7.8858
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP2; CTRP1 1.1694 3.5709 1.1088 26.0914
JHUEM-2 CTRP2; CTRP1 1.8579 3.6842 1.8233 21.4213
RL95-2 CTRP2 2.3444 4.4777 2.2309 18.3769
HEC-108 CTRP2; CTRP1 2.954 4.2019 2.9268 14.1012
HEC-265 CTRP2; CTRP1 3.0081 3.8823 3.0035 13.6646
HEC-6 CTRP2; CTRP1 3.2755 4.8123 3.174 12.2198
HEC-251 CTRP2; CTRP1 3.2935 4.3604 3.2685 11.8342
KLE CTRP2; CTRP1 3.3316 4.9804 3.1947 11.9726
MFE-319 CTRP2; CTRP1 3.362 4.144 3.356 11.3141
JHUEM-7 CTRP2 3.4625 6.2147 2.901 12.6171
HEC-1-B CTRP2 3.4878 5.4897 3.2062 11.3805
HEC-50B CTRP2 3.838 8.1711 2.3892 13.7185
JHUEM-1 CTRP2 4.1917 5.0713 4.1063 5.9803
JHUEM-3 CTRP2 4.2136 5.2867 4.0617 6.08
HEC-59 CTRP2; CTRP1 4.2381 4.9066 4.1997 5.5947
AN3-CA CTRP2 4.3126 5.1584 4.212 5.2323
MFE-296 CTRP2 4.3547 5.9066 3.9581 6.0991
ESS-1 CTRP2 4.3807 4.9327 4.3472 4.5371
HEC-1-A CTRP2 4.3892 5.6947 4.0866 5.4998
EN CTRP2 4.4443 4.9337 4.4161 4.0948
EFE-184 CTRP2 4.6255 6.5285 3.9297 5.5619
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 3.8995 5.2262 3.7443 8.266
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMRC-3 CTRP2 2.6032 4.734 2.4582 16.7647
CAL-54 CTRP2 2.9883 5.2961 2.727 14.6225
UO-31 CTRP2 3.0202 4.9539 2.8594 14.0456
VMRC-RCW CTRP2; CTRP1 3.5935 4.7195 3.5379 9.9431
KMRC-20 CTRP2 3.6571 6.5538 2.9589 11.8722
BFTC-909 CTRP2 4.1917 5.628 3.9083 6.7261
769-P CTRP2 4.2747 7.0252 3.3571 8.7325
OS-RC-2 CTRP2 4.3377 5.9635 3.9154 6.3126
KMRC-2 CTRP2 4.3618 4.8686 4.339 4.6254
TUHR14TKB CTRP2 4.4017 8.2096 2.8988 10.3382
TUHR4TKB CTRP2 4.4045 5.1552 4.3129 4.5887
RCC10RGB CTRP2; CTRP1 4.4378 5.3283 4.2923 4.6609
SNU-1272 CTRP2 4.4823 5.0237 4.4365 3.9047
ACHN CTRP2 4.4987 5.3594 4.3407 4.2146
Caki-1 CTRP2 4.515 8.2261 2.9933 9.6987
KMRC-1 CTRP2 4.5298 4.9091 4.5131 3.4852
786-O CTRP2 4.5388 5.0909 4.4793 3.5781
Caki-2 CTRP2 4.541 4.9073 4.5255 3.4064
VMRC-RCZ CTRP2 4.5467 5.2283 4.4419 3.694
TUHR10TKB CTRP2 4.5727 5.0759 4.5207 3.3253
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW48 CTRP2; CTRP1 0.9761 2.5873 0.9705 27.1923
SNU-175 CTRP1 1.0925 3.8734 0.9868 55.8594
LS180 CTRP2; CTRP1 1.1613 3.3126 1.1254 26.062
HT115 CTRP2; CTRP1 1.2726 2.7187 1.2685 25.2141
T84 CTRP2 1.3242 2.7797 1.3194 24.8005
HCT 15 CTRP2 1.4473 2.9938 1.4389 23.9924
LS513 CTRP2; CTRP1 1.5297 2.5416 1.5292 23.4909
SNU-C4 CTRP2; CTRP1 1.6862 4.0633 1.5944 22.7595
CCK-81 CTRP2 1.7883 3.3361 1.7746 21.7382
OUMS-23 CTRP2 1.9983 3.6262 1.9744 20.374
CW-2 CTRP2; CTRP1 2.0269 5.2444 1.6975 21.3351
SNU-81 CTRP1 2.1183 5.8086 1.6176 43.8005
SNU-C5 CTRP2; CTRP1 2.3542 5.1598 2.079 18.9661
GP2d CTRP2; CTRP1 2.3707 4.1455 2.3147 18.0814
SNU-1033 CTRP2 2.4757 5.1646 2.2074 18.0551
CL-40 CTRP1 2.5093 5.0588 2.2765 37.8145
CL-34 CTRP1 2.5412 4.5493 2.4318 36.6754
LS411N CTRP2; CTRP1 2.5438 3.9224 2.5214 16.8147
LS1034 CTRP2 2.6059 5.274 2.3171 17.2643
DLD-1 CTRP2; CTRP1 2.7043 4.068 2.677 15.7631
NCI-H508 CTRP2; CTRP1 2.8132 4.5673 2.7226 15.2567
C2BBe1 CTRP2; CTRP1 2.9964 4.8188 2.8688 14.1683
SK-CO-1 CTRP2; CTRP1 3.0321 4.4575 2.9774 13.6756
SNU-407 CTRP2 3.052 4.8805 2.9125 13.7575
NCI-H747 CTRP2 3.1397 5.284 2.8957 13.553
SNU-C1 CTRP2 3.1408 4.9688 2.9871 13.2178
COLO 320 CTRP1 3.1426 9.2255 1.2223 37.5746
LoVo CTRP2; CTRP1 3.1428 4.8944 3.0103 13.2119
COLO205 CTRP2; CTRP1 3.179 4.5645 3.1181 12.7193
HCT 116 CTRP2; CTRP1 3.3009 4.4801 3.2618 11.8329
SNU-C2A CTRP2; CTRP1 3.3013 4.7336 3.2187 11.9815
SW948 CTRP1 3.334 5.4987 3.0403 26.8288
KM12 CTRP2; CTRP1 3.3628 5.4516 3.0876 12.2705
CL-11 CTRP2 3.4129 6.8775 2.5663 14.0611
RKO CTRP2; CTRP1 3.466 4.8997 3.3612 10.9646
SNU-61 CTRP2; CTRP1 3.5017 5.8848 3.0795 11.9052
HT-55 CTRP2; CTRP1 3.5813 4.8463 3.499 10.1183
SW1463 CTRP2 3.6131 5.5453 3.3218 10.5858
NCI-H716 CTRP2 3.6609 6.3156 3.0658 11.4409
SW1417 CTRP2 3.6874 5.6403 3.3667 10.2045
HCT 8 CTRP2; CTRP1 3.8396 5.1015 3.7164 8.5473
SW620 CTRP2; CTRP1 3.8494 5.4149 3.627 8.8477
SNU-1040 CTRP1 4.0918 5.0061 4.0175 14.37
HT-29 CTRP2; CTRP1 4.1821 5.0977 4.0911 6.155
COLO201 CTRP2 4.2497 6.8254 3.4282 8.5005
HCC-56 CTRP2 4.267 4.9388 4.2223 5.3335
RCM-1 [Human ESC] CTRP2; CTRP1 4.2724 5.0654 4.1987 5.4923
SW403 CTRP1 4.2924 4.9308 4.2535 11.2362
COLO 678 CTRP2; CTRP1 4.3009 5.2848 4.1606 5.5482
MDST8 CTRP2; CTRP1 4.3494 4.8566 4.329 4.7916
SNU-503 CTRP2 4.3819 8.9339 2.5232 11.936
LS123 CTRP2; CTRP1 4.499 5.6417 4.2287 4.7412
SW480 CTRP1 4.4998 6.609 3.7798 14.0554
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 CTRP2 1.9296 3.5365 1.9092 20.8197
SNU-182 CTRP2 2.1721 5.3191 1.8307 20.3386
HuH-6 CTRP2 2.3217 4.615 2.1783 18.633
Li-7 CTRP2 2.5312 4.2812 2.4661 16.9647
SNU-398 CTRP2; CTRP1 3.0618 5.0345 2.886 13.9058
SNU-878 CTRP2 3.1467 4.5499 3.0844 12.8553
SNU-449 CTRP2; CTRP1 3.6103 4.6909 3.5611 9.8091
Hep-G2 CTRP2; CTRP1 3.6443 5.224 3.467 10.0412
HuH-1 CTRP2 3.7421 5.5674 3.4525 9.7245
JHH-6 CTRP2; CTRP1 3.8385 4.2397 3.838 8.1243
HLF CTRP2 3.9886 6.1596 3.4719 8.9777
Hep 3B2.1-7 CTRP2 4.1303 5.4441 3.9149 6.8716
JHH-5 CTRP2 4.3407 6.9648 3.4492 8.1992
PLC/PRF/5 CTRP2 4.3629 4.9137 4.3318 4.6471
JHH-4 CTRP2 4.3638 6.5805 3.6551 7.3013
SNU-475 CTRP2 4.3885 8.1342 2.9238 10.2632
JHH-2 CTRP2 4.4355 5.4441 4.2401 4.7763
SNU-423 CTRP2 4.5314 5.1452 4.4541 3.6931
SNU-886 CTRP2 4.6719 5.7128 4.3651 4.2417
SK-HEP-1 CTRP2 4.6734 5.2357 4.5749 2.8309
SNU-387 CTRP2 7.5787 10.1029 4.1865 0.7997
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 158 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCLC-21H CTRP1 -0.3221 0.7005 -0.3221 76.6698
NCI-H2444 CTRP2 -0.2241 17.2421 -5.8557 43.4803
COR-L51 CTRP1 -0.1031 1.9407 -0.1103 72.0689
HCC1588 CTRP2 1.6777 3.1453 1.6691 22.4579
NCI-H2081 CTRP2; CTRP1 1.7376 3.7311 1.6921 22.2587
NCI-H810 CTRP2; CTRP1 1.7926 3.1254 1.7871 21.7579
DMS 53 CTRP2 1.8175 3.4693 1.7973 21.5658
NCI-H211 CTRP2 1.8331 4.0515 1.7525 21.6677
NCI-H1341 CTRP2 1.8367 3.1708 1.8306 21.3906
MOR/CPR CTRP2 1.8739 3.1134 1.8698 21.1358
DMS 454 CTRP2 1.8741 4.6715 1.6788 21.7958
NCI-H69 CTRP2 1.9769 4.8939 1.7366 21.2715
NCI-H2087 CTRP2 2.142 6.1056 1.5348 21.5135
DMS 273 CTRP2; CTRP1 2.2943 3.1561 2.2936 18.4026
BEN CTRP2; CTRP1 2.3056 4.1923 2.2387 18.5522
NCI-H1734 CTRP2 2.3638 4.3934 2.2675 18.1875
NCI-H82 CTRP1 2.5158 3.0492 2.5158 36.3277
SHP-77 CTRP2; CTRP1 2.5236 4.3589 2.4469 17.1353
NCI-H1568 CTRP2; CTRP1 2.5251 3.6928 2.5162 16.8938
COLO 668 CTRP2; CTRP1 2.5267 4.7783 2.3666 17.407
NCI-H1694 CTRP2; CTRP1 2.5387 3.941 2.5145 16.8548
NCI-H2106 CTRP2 2.5534 5.0941 2.3121 17.4408
NCI-H1693 CTRP2 2.5761 5.1391 2.3243 17.328
NCI-H1930 CTRP1 2.5882 3.936 2.5667 35.4429
LXF 289 CTRP2; CTRP1 2.6581 3.9905 2.6354 16.0552
Calu-6 CTRP2; CTRP1 2.6663 4.4125 2.5917 16.1785
A-549 CTRP2; CTRP1 2.6691 3.8366 2.6574 15.9449
NCI-H2029 CTRP2; CTRP1 2.6713 4.5685 2.5689 16.2417
NCI-H1184 CTRP2 2.6741 6.2084 2.0674 17.9974
NCI-H1963 CTRP1 2.697 4.1944 2.6557 34.0295
NCI-H1048 CTRP1 2.7053 3.4747 2.7044 33.6267
VMRC-LCD CTRP2; CTRP1 2.7267 4.3103 2.6721 15.7075
NCI-H23 CTRP2; CTRP1 2.7286 4.499 2.6439 15.799
HCC1833 CTRP2; CTRP1 2.7319 5.4809 2.3927 16.6924
ChaGo-K-1 CTRP2; CTRP1 2.7462 3.8912 2.734 15.4334
HCC95 CTRP2 2.7576 4.3637 2.6962 15.4437
Calu-3 CTRP2; CTRP1 2.7731 3.9746 2.7566 15.269
NCI-H1299 CTRP2; CTRP1 2.8126 3.8332 2.8053 14.9752
DV-90 CTRP2; CTRP1 2.8436 4.4029 2.7837 14.9478
NCI-H727 CTRP2; CTRP1 2.8438 4.6542 2.7387 15.104
NCI-H1836 CTRP1 2.8457 6.2016 2.2576 35.2895
NCI-H1373 CTRP2; CTRP1 2.8646 4.5554 2.7805 14.892
NCI-H520 CTRP2 2.8776 4.7075 2.7624 14.8323
NCI-H1792 CTRP2; CTRP1 2.9184 4.1687 2.8926 14.3333
NCI-H1437 CTRP1 2.934 3.9856 2.9228 30.4339
NCI-H596 CTRP1 2.9698 4.0907 2.9531 29.964
COR-L279 CTRP1 2.9729 3.7542 2.9709 29.8118
NCI-H2122 CTRP2; CTRP1 2.9833 4.8993 2.8352 14.3284
Lu-99 CTRP2; CTRP1 2.9876 4.6308 2.8993 14.0884
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 2.9886 4.0019 2.9784 13.8132
NCI-H1944 CTRP1 2.9935 4.7807 2.8742 30.3598
HCC44 CTRP2; CTRP1 2.9955 4.4178 2.9442 13.9073
NCI-H1105 CTRP2; CTRP1 3.0293 5.5517 2.6921 14.7127
NCI-H1975 CTRP2; CTRP1 3.0401 4.8691 2.9045 13.9057
COR-L88 CTRP1 3.0536 4.2003 3.0317 28.8028
EBC-1 CTRP2; CTRP1 3.0728 4.5331 3.0091 13.4359
LCLC-97TM1 CTRP2; CTRP1 3.0941 4.5212 3.0339 13.282
KNS-62 CTRP2; CTRP1 3.1081 4.2747 3.0818 13.0725
HCC78 CTRP2; CTRP1 3.1619 4.7194 3.0704 12.94
LCLC-103H CTRP2; CTRP1 3.1691 4.3256 3.1408 12.6735
NCI-H1573 CTRP2; CTRP1 3.1795 4.528 3.1245 12.6957
NCI-H1666 CTRP2; CTRP1 3.1812 4.6119 3.1121 12.7335
NCI-H2291 CTRP2 3.208 7.6523 2.0115 16.7808
NCI-H2405 CTRP2; CTRP1 3.2153 4.3859 3.1829 12.3799
DMS 79 CTRP2 3.2315 5.0622 3.0611 12.6743
NCI-H1915 CTRP2; CTRP1 3.2918 4.18 3.2817 11.7949
NCI-H1581 CTRP2 3.2994 4.9905 3.1544 12.1311
HCC33 CTRP1 3.31 4.7238 3.2302 25.5673
NCI-H358 CTRP2; CTRP1 3.31 5.0065 3.1644 12.1474
LC-1/sq-SF CTRP2; CTRP1 3.3134 4.576 3.2608 11.7963
NCI-H1155 CTRP2 3.3146 4.6365 3.2503 11.744
NCI-H2196 CTRP2 3.3655 6.9101 2.5034 14.433
NCI-H2141 CTRP2; CTRP1 3.3891 5.808 2.9886 12.5668
NCI-H3255 CTRP1 3.3934 8.7295 1.701 34.2879
NCI-H1355 CTRP2; CTRP1 3.4034 4.8841 3.2967 11.3874
NCI-H1838 CTRP2 3.4644 5.6349 3.1292 11.7369
NCI-H522 CTRP1 3.4722 5.0609 3.3267 23.7508
NCI-H292 CTRP2 3.4726 5.6673 3.1262 11.7251
NCI-H1793 CTRP2; CTRP1 3.4973 4.5031 3.4681 10.4921
NCI-H2342 CTRP2; CTRP1 3.4985 5.1411 3.3329 10.9669
NCI-H1435 CTRP2; CTRP1 3.5235 4.5437 3.4907 10.33
COR-L95 CTRP2 3.5276 7.6715 2.3222 14.7412
COR-L23 CTRP1 3.5371 5.9563 3.0891 25.1549
SW1271 CTRP2 3.5872 6.3014 2.9952 11.9138
SK-MES-1 CTRP2 3.5982 5.7794 3.2185 11.0196
EPLC-272H CTRP2; CTRP1 3.6096 5.1584 3.4489 10.2113
LK2 CTRP2 3.6287 4.7979 3.559 9.6714
NCI-H2023 CTRP2; CTRP1 3.6375 4.8056 3.5687 9.6967
NCI-H1876 CTRP1 3.642 6.3287 3.0463 24.8291
T3M-10 CTRP2; CTRP1 3.6501 5.0007 3.537 9.7702
NCI-H2286 CTRP2; CTRP1 3.6651 4.8252 3.5946 9.5192
RERF-LC-KJ CTRP1 3.6824 4.9264 3.5906 20.3445
NCI-H650 CTRP2; CTRP1 3.6875 5.1644 3.5321 9.6744
NCI-H441 CTRP2; CTRP1 3.6988 5.1797 3.5399 9.6125
COLO 699 CTRP2; CTRP1 3.7135 5.414 3.4803 9.7888
NCI-H2009 CTRP2; CTRP1 3.7464 5.4924 3.4885 9.6629
NCI-H446 CTRP2 3.7543 5.9524 3.3154 10.2159
NCI-H661 CTRP2; CTRP1 3.7709 5.4719 3.5222 9.4665
CAL-12T CTRP2; CTRP1 3.7812 7.5503 2.636 12.9358
NCI-H1755 CTRP2; CTRP1 3.7847 5.2965 3.5968 9.1484
NCI-H2126 CTRP2; CTRP1 3.8362 4.9898 3.7428 8.4625
Lu-65 CTRP2; CTRP1 3.8798 4.8916 3.8137 8.0754
RERF-LC-A1 CTRP2 3.891 6.2672 3.3245 9.8154
HCC15 CTRP2; CTRP1 3.897 5.456 3.6639 8.5725
NCI-H841 CTRP2; CTRP1 3.9158 5.3996 3.7042 8.367
Sq-1 CTRP2; CTRP1 3.9749 5.3606 3.7817 7.9066
HCC4006 CTRP2; CTRP1 4.023 5.1633 3.8982 7.3348
NCI-H2073 CTRP1 4.0576 5.2237 3.917 15.3742
SW1573 CTRP2 4.0688 5.8332 3.6946 7.8899
HCC2935 CTRP1 4.0851 6.957 3.2126 20.98
NCI-H1092 CTRP2 4.1552 6.0343 3.6979 7.6485
HCC1359 CTRP1 4.1674 4.7591 4.1484 12.8733
SK-LU-1 CTRP2; CTRP1 4.1707 5.5041 3.9399 6.7523
RERF-LC-Ad2 CTRP2 4.2462 7.6424 3.0323 10.1346
NCI-H1395 CTRP2 4.2635 6.317 3.6798 7.4456
LUDLU-1 CTRP2 4.2659 5.6527 3.9762 6.2612
NCI-H322 CTRP2 4.269 5.6034 3.9998 6.1611
NCI-H1703 CTRP2 4.2714 5.8109 3.9148 6.4872
HCC2279 CTRP2 4.2869 5.3582 4.1149 5.67
NCI-H2085 CTRP2 4.2921 8.6373 2.588 11.8653
HCC2108 CTRP2; CTRP1 4.3054 5.643 4.0269 6.0469
NCI-H647 CTRP2 4.3072 5.3184 4.1513 5.4743
NCI-H526 CTRP2 4.3302 6.1004 3.8458 6.6105
NCI-H1781 CTRP1 4.345 6.2925 3.779 14.8657
DMS 114 CTRP2 4.3542 8.497 2.7138 11.2089
HCC366 CTRP2 4.3686 5.8135 4.0136 5.8424
NCI-H1651 CTRP2 4.3716 6.313 3.7888 6.738
NCI-H460 CTRP2; CTRP1 4.3879 4.9389 4.3555 4.5772
NCI-H2170 CTRP2 4.3891 6.8287 3.5609 7.6274
NCI-H1869 CTRP2 4.3946 6.0759 3.9216 6.1444
RERF-LC-MS CTRP2 4.3982 5.0662 4.3331 4.5335
LOU-NH91 CTRP2 4.4023 5.4202 4.2145 4.9663
NCI-H838 CTRP2 4.4135 4.9217 4.385 4.3009
NCI-H1650 CTRP2 4.4244 6.7796 3.6182 7.3097
HOP-62 CTRP2 4.4332 5.253 4.3107 4.5133
SBC-5 CTRP2 4.447 4.9305 4.4196 4.0739
COR-L105 CTRP2 4.4571 6.8979 3.592 7.3418
NCI-H2110 CTRP2; CTRP1 4.464 7.6654 3.2318 8.9015
NCI-H1623 CTRP2 4.4855 5.1393 4.4061 4.0055
NCI-H889 CTRP2 4.5095 6.0315 4.0562 5.3163
HCC827 CTRP2; CTRP1 4.5294 6.5641 3.8296 6.2826
HOP-92 CTRP2 4.5348 5.3815 4.3702 4.0016
PC-14 CTRP2 4.5535 11.2655 1.5159 15.6323
NCI-H1339 CTRP2 4.5739 5.0467 4.5303 3.287
NCI-H1563 CTRP2 4.5849 5.1498 4.5107 3.3262
EKVX CTRP2 4.5861 6.1453 4.0773 5.0458
RERF-LC-Ad1 CTRP2 4.6044 4.9581 4.5847 2.999
NCI-H196 CTRP2 4.6101 5.3532 4.461 3.4442
IA-LM CTRP2 4.616 5.3961 4.4494 3.4734
Calu-1 CTRP2 4.6338 5.081 4.5858 2.905
NCI-H2172 CTRP2; CTRP1 4.6594 5.2613 4.5547 3.0406
HCC1438 CTRP2 4.6826 5.1164 4.6278 2.6058
NCI-H2228 CTRP2 4.7561 14.4436 0.1024 20.3121
NCI-H2030 CTRP2; CTRP1 5.4931 8.6059 3.6329 5.201
HCC1195 CTRP2; CTRP1 5.7691 7.7419 4.2531 2.2344
HCC1171 CTRP2 5.8258 14.6889 0.8569 15.6196
NCI-H226 CTRP2 11.8528 31.7355 -3.1424 18.0973
Hs 888.Lu CTRP2 4.743 5.529 4.5208 2.861
⏷ Show the Full List of 158 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 1.9226 5.2026 1.593 21.9526
COV434 CTRP2; CTRP1 1.293 3.5812 1.2384 25.2486
OVK18 CTRP2; CTRP1 1.9949 4.7655 1.7904 21.1004
OVKATE CTRP1 2.2632 4.3939 2.1603 40.5129
RMG-I CTRP2; CTRP1 2.5433 5.2725 2.2524 17.7672
A2780 CTRP2; CTRP1 2.7212 4.5371 2.6289 15.8745
HEY A8 CTRP2; CTRP1 2.8061 3.9688 2.7914 15.0431
SNU-119 CTRP2 2.8256 4.9319 2.6528 15.3833
OVCAR-4 CTRP2; CTRP1 2.8515 5.1049 2.6372 15.4417
RMUG-S CTRP1 2.9447 4.9072 2.7912 31.2922
OVCAR-8 CTRP2; CTRP1 2.9463 3.9463 2.9376 14.0898
COV644 CTRP2; CTRP1 2.9614 5.0812 2.7637 14.6517
OAW28 CTRP2 3.0061 5.1842 2.7803 14.3742
JHOS-4 CTRP1 3.238 4.2903 3.2171 26.1614
TYK-nu CTRP2; CTRP1 3.2494 4.4633 3.2091 12.18
OVMANA CTRP1 3.2978 4.6673 3.228 25.6667
ONCO-DG-1 CTRP2 3.529 5.418 3.2753 11.0028
SNU-8 CTRP2 3.556 5.0869 3.4083 10.434
OVCAR-5 CTRP2 3.7065 5.5432 3.4231 9.9372
OV-90 CTRP2; CTRP1 3.9425 5.1611 3.8112 7.8932
OVTOKO CTRP2 3.9919 6.7037 3.231 9.9309
IGROV-1 CTRP2; CTRP1 4.0119 5.6915 3.6977 8.1205
COV318 CTRP1 4.0384 5.0015 3.9604 15.1592
OC 314 CTRP2 4.1046 4.7703 4.0785 6.3501
DOV13 CTRP2 4.1461 5.9628 3.7197 7.5858
Kuramochi CTRP2 4.1981 5.9195 3.792 7.1641
MCAS CTRP2 4.2044 6.4751 3.5481 8.1237
COV362 CTRP2; CTRP1 4.2094 4.9429 4.1607 5.8218
Caov-3 CTRP2; CTRP1 4.2344 4.9159 4.1937 5.6276
ES2 CTRP2 4.2548 5.0512 4.1808 5.5195
SNU-840 CTRP2; CTRP1 4.2628 5.5488 4.0204 6.1883
OAW42 CTRP2; CTRP1 4.3409 4.8621 4.3189 4.8537
OV56 CTRP2 4.3792 4.8489 4.361 4.4936
TOV-21G CTRP2 4.4166 5.1699 4.3213 4.5217
SK-OV-3 CTRP2; CTRP1 4.4425 4.9493 4.4127 4.2049
OV7 CTRP2; CTRP1 4.4963 4.9823 4.464 3.8557
JHOS-2 CTRP2 4.5203 4.9753 4.4897 3.5971
OVISE CTRP2 4.5253 4.8873 4.5117 3.5045
FU-OV-1 CTRP2 4.6038 16.0209 -0.8152 23.458
OVSAHO CTRP2 4.7219 10.4216 2.0825 13.0268
JHOC-5 CTRP2; CTRP1 4.8166 7.0055 3.877 5.4508
EFO-21 CTRP2; CTRP1 4.8748 5.938 4.4578 2.9032
EFO-27 CTRP2; CTRP1 6.1732 9.2137 3.8206 3.4029
JHOM-1 CTRP2; CTRP1 6.4517 10.3657 3.4572 4.4655
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 2.9102 4.8182 2.7729 14.6936
P-STS CTRP2 2.9427 6.0634 2.4096 15.9421
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 3.0767 5.3461 2.8076 14.0634
Yamato-SS CTRP2 4.4313 5.0194 4.3819 4.2567
TE 441.T CTRP2 1.6367 3.7635 1.581 22.8908
TE 617.T CTRP2 2.5739 4.4678 2.481 16.7765
G-401 CTRP1 2.6005 4.0919 2.5651 35.3615
TTC-709 CTRP2 2.8592 4.9767 2.6777 15.191
Tm87-16 CTRP2 3.0125 5.2504 2.7674 14.4024
A-204 CTRP2 3.1905 5.1138 3.0018 13.0134
Rh41 CTRP2 3.2468 4.8856 3.1236 12.4034
G-402 CTRP2 3.615 5.7141 3.2614 10.8091
BT-16 CTRP2 3.6382 5.6626 3.3056 10.5758
KYM-1 CTRP2 3.649 5.3792 3.4186 10.1198
RKN CTRP2; CTRP1 3.6915 6.4627 3.0399 11.5461
RD CTRP2 3.7337 6.3434 3.1293 10.9985
GCT CTRP2 3.9048 5.8471 3.5169 9.0248
Rh18 CTRP2 4.0528 10.0261 1.6856 16.0521
BT-12 CTRP2 4.1091 6.5211 3.432 8.8289
SW982 CTRP2 4.3177 5.3596 4.1474 5.4591
HT-1080 CTRP2; CTRP1 4.4017 4.8717 4.3827 4.4387
Hs 729.T CTRP2 4.4072 7.8206 3.095 9.5117
SK-UT-1 CTRP2 4.4537 7.6666 3.2135 8.9168
SK-LMS-1 CTRP2 4.4992 5.3943 4.3274 4.2642
MES-SA CTRP2 6.5086 7.6687 4.6622 0.2131
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.2893 7.4873 3.148 9.5587
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 2.7074 4.2044 2.6655 15.7922
NCI-H28 CTRP2; CTRP1 3.1384 5.0092 2.9764 13.3471
NCI-H2452 CTRP2 3.2147 8.8184 1.4777 18.846
NCI-H2052 CTRP2; CTRP1 4.2834 6.0729 3.8176 6.9303
MPP 89 CTRP2 4.3257 6.4827 3.6641 7.3562
IST-Mes1 CTRP2 4.445 5.4056 4.2655 4.652
JL-1 CTRP2 4.7119 5.4171 4.5398 2.8643
ACC-MESO-1 CTRP2 5.2223 8.4704 3.4773 6.2511
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP2; CTRP1 3.0435 3.988 3.0356 13.4403
22Rv1 CTRP2 3.2893 5.7008 2.9168 13.0381
VCaP CTRP2 3.9506 6.4881 3.2875 9.8089
LNCaP clone FGC CTRP2 4.221 6.476 3.5641 8.018
DU145 CTRP2 4.5404 5.2146 4.4401 3.7189
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.601 4.9983 2.3903 17.0138
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS CTRP2; CTRP1 0.7983 3.307 0.7449 28.5366
SNU-620 CTRP2 1.0086 2.691 1.0007 26.9134
GSS CTRP2 1.5338 2.1996 1.5338 23.3884
HGC-27 CTRP2 2.3269 4.1571 2.2654 18.3131
SNU-5 CTRP2 2.5307 4.7596 2.3733 17.2912
ECC10 CTRP2 2.594 4.2351 2.5398 16.5088
Fu97 CTRP2; CTRP1 2.7687 3.9564 2.7533 15.2942
SNU-719 CTRP2 2.8853 6.623 2.1266 17.185
SNU-1 CTRP2 2.9405 6.1342 2.3801 16.0607
SNU-601 CTRP2 3.1607 4.9613 3.0107 13.0718
KE-39 CTRP2 3.2205 5.608 2.8758 13.3897
23132/87 CTRP2 3.2869 5.2924 3.0533 12.5364
NUGC-3 CTRP2 3.3796 5.1309 3.2032 11.7113
MKN74 CTRP2; CTRP1 3.4695 5.0399 3.3295 11.067
IM95 CTRP2 3.4841 5.4246 3.2245 11.3231
NUGC-4 CTRP2; CTRP1 3.5004 4.5022 3.4714 10.4709
MKN1 CTRP2 3.7297 5.8852 3.3166 10.2788
KATO III CTRP2 3.8699 6.155 3.3513 9.7656
HuG1-N CTRP2 3.8854 6.3224 3.2947 9.9481
MKN7 CTRP2; CTRP1 3.9644 5.021 3.8746 7.5972
GSU CTRP2 4.1437 4.8519 4.1065 6.128
SNU-668 CTRP2 4.1871 5.4631 3.9686 6.5074
Hs 746.T CTRP2 4.2233 5.5723 3.9642 6.4234
SNU-216 CTRP2 4.2532 5.5703 3.9965 6.217
SH-10-TC CTRP2; CTRP1 4.4584 4.8999 4.4392 4.062
ECC12 CTRP2 4.4885 4.9504 4.4606 3.7994
LMSU CTRP2 4.6561 5.1276 4.5953 2.8039
MKN45 CTRP2 6.428 20.7397 -1.6821 22.3458
SNU-685 CTRP2 4.2417 4.9446 4.1935 5.5144
SNG-M CTRP2; CTRP1 4.307 5.1766 4.2034 5.3719
SNU-1077 CTRP2 4.3765 5.5594 4.1308 5.3607
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8505C CTRP2 2.7357 5.0803 2.515 16.1539
TT CTRP2 3.5883 5.6424 3.2597 10.891
8305C CTRP2 3.8756 5.2224 3.7161 8.3522
ML-1 [Human leukemia] CTRP2 4.1135 13.5814 -0.0227 22.0927
BHT-101 CTRP2 4.156 5.7266 3.8303 7.1261
FTC-238 CTRP2 4.3053 6.7282 3.5283 7.9589
CAL-62 CTRP2 4.3219 5.2468 4.1926 5.2771
CGTH-W-1 CTRP2 4.3329 5.3455 4.169 5.3342
SW579 CTRP2 4.3693 4.8868 4.3439 4.5844
B-CPAP CTRP2 4.3836 5.1118 4.3037 4.6845
TT2609-C02 CTRP2 4.5926 7.373 3.4851 7.4818
FTC-133 CTRP2 4.9025 5.6618 4.6107 2.1169
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1214 CTRP2 1.5379 3.9952 1.4446 23.6777
Detroit 562 CTRP2 1.5779 3.1825 1.5653 23.1366
YD-10B CTRP2 1.5791 3.952 1.4952 23.3712
BHY CTRP2 2.5128 4.5502 2.3991 17.2561
SCC-25 CTRP2 2.5872 4.9575 2.386 17.0718
HSC-3 CTRP2 2.9932 4.6824 2.8933 14.0089
BICR 18 CTRP2 3.0185 5.9136 2.5474 15.2049
CAL-33 CTRP2 3.1455 5.7124 2.7578 14.0488
HSC-2 CTRP2; CTRP1 3.2285 4.2175 3.2133 12.2335
YD-8 CTRP2 3.5405 6.3793 2.9137 12.3578
SNU-899 CTRP2 3.6509 5.3078 3.4444 10.0184
SNU-1076 CTRP2 4.1464 5.5109 3.9067 6.8577
BICR 16 CTRP2 4.2331 8.3738 2.6632 11.6869
BICR 6 CTRP2 4.2372 4.7783 4.2193 5.4383
SCC-9 CTRP2; CTRP1 4.2759 5.2506 4.1453 5.6778
PE/CA-PJ49 CTRP2 4.3148 4.9656 4.2683 5.0216
SNU-46 CTRP2 4.3401 5.2982 4.1941 5.2192
BICR 31 CTRP2 4.4056 5.4549 4.2041 4.997
HSC-4 CTRP2 4.4193 4.9228 4.3911 4.2614
SCC-4 CTRP2 4.4732 5.1043 4.4037 4.0507
FaDu CTRP2 4.5019 4.9585 4.4734 3.7124
CAL-27 CTRP2 4.5554 5.0315 4.5142 3.4016
SNU-1066 CTRP2 4.6356 5.9308 4.2271 4.3152
PE/CA-PJ41 (clone D2) CTRP2 4.6698 5.2103 4.5808 2.8189
SNU-1041 CTRP2 6.6652 13.5361 2.0618 9.6314
BICR 56 CTRP2 7.023 8.3931 4.5993 0.1704
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 1.742 2.4004 1.742 22.0011
HT-1376 CTRP2; CTRP1 2.7776 3.991 2.7601 15.2422
CAL-29 CTRP2 2.982 4.78 2.8599 14.1619
U-BLC1 CTRP2 2.9847 4.5428 2.911 13.9737
RT-112 CTRP2 3.1541 5.7118 2.7672 13.989
5637 CTRP2; CTRP1 3.1562 4.6043 3.0866 12.9014
RT-4 CTRP2; CTRP1 3.2138 4.3262 3.1881 12.367
JMSU-1 CTRP2 3.2718 5.2771 3.0416 12.6243
VM-CUB-1 CTRP2 3.6058 6.1861 3.063 11.5992
TCCSUP CTRP2 3.62 4.9173 3.5227 9.8272
KMBC-2 CTRP2; CTRP1 3.6916 4.9141 3.6037 9.4044
647V CTRP2 4.2124 5.6635 3.9156 6.6418
HT-1197 CTRP2 4.2642 5.2073 4.1435 5.6281
SCaBER CTRP2 4.4227 4.8735 4.4037 4.2066
UM-UC-3 CTRP2; CTRP1 4.4673 5.4107 4.292 4.5798
J82 CTRP2 4.4767 5.6662 4.1891 4.8658
T24 CTRP2 4.5137 6.6402 3.7703 6.4763
639V CTRP2 4.5666 4.9707 4.5411 3.2712
BC-3C CTRP2 4.5699 5.0023 4.5374 3.2736
KU-19-19 CTRP2 4.8272 8.365 3.1998 8.1821
SW1710 CTRP2 5.9523 14.3338 1.133 14.3817
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 4.5104 4.8862 4.4959 3.6069

References

1 Rational design of 7-arylquinolines as non-competitive metabotropic glutamate receptor subtype 5 antagonists. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4415-8.